𝕏

Task 55504044

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_308_0
Workunit 26353141
Created 1 Jul 2024, 14:47:09 UTC
Sent 1 Jul 2024, 15:39:50 UTC
Report deadline 5 Jul 2024, 1:15:50 UTC
Received 3 Jul 2024, 6:40:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 225520
Run time 2 hours 30 min 46 sec
CPU time 2 hours 4 min 29 sec
Validate state Valid
Credit 61.91
Device peak FLOPS 4.27 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.93 MB
Peak swap size 6.41 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_308.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_308_0_r1391607247_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_308_0_r1391607247_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.547620
     * GNaL_b in INaL: 0.006012
     * Gto_b in Ito: 0.082879
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031319
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.166140
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.436659
     * GKb_b in IKb: 0.003788
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030313
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7498237, states[0] = -95.129999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16997741, states[0] = -95.098004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26216353, states[0] = -94.912364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33580513, states[0] = -3.771522, states[40]= 0.003664
Saving checkpoint... 
Iteration: 45308997, states[0] = -94.994468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59048054, states[0] = 12.359652, states[40]= 0.005048
Saving checkpoint... 
Iteration: 71879826, states[0] = -95.015320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84593912, states[0] = -13.239352, states[40]= 0.001734
Saving checkpoint... 
Iteration: 98310119, states[0] = -94.973562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110208777, states[0] = -94.849529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122636550, states[0] = -54.452456, states[40]= 0.000014
Saving checkpoint... 
Iteration: 136045329, states[0] = 13.656193, states[40]= 0.005104
Saving checkpoint... 
Iteration: 147893392, states[0] = -95.009075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159702537, states[0] = -94.834486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173052124, states[0] = 11.075764, states[40]= 0.004978
Saving checkpoint... 
Iteration: 185367114, states[0] = -94.998872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197212285, states[0] = -94.852347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206003627, states[0] = 33.952830, states[40]= 0.148369
Saving checkpoint... 
Iteration: 219376335, states[0] = -95.002126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230873275, states[0] = -95.000933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242708977, states[0] = -94.845968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254124973, states[0] = -42.042784, states[40]= 0.000097
Saving checkpoint... 
Iteration: 266265303, states[0] = -94.928569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278157708, states[0] = -83.235653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291704303, states[0] = -94.836957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304448184, states[0] = -95.021171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317258681, states[0] = -94.921002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330062829, states[0] = 6.689812, states[40]= 0.004819
Saving checkpoint... 
Iteration: 342510987, states[0] = 23.189209, states[40]= 0.042224
Saving checkpoint... 
Iteration: 352410498, states[0] = -95.012638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365226036, states[0] = -94.875664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378395553, states[0] = -95.008337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389922893, states[0] = -95.015740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402503923, states[0] = 32.563228, states[40]= 0.151669
Saving checkpoint... 
Iteration: 414079346, states[0] = -1.668918, states[40]= 0.004008
Saving checkpoint... 
Iteration: 426920629, states[0] = -95.015171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439794650, states[0] = -94.956204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452107672, states[0] = -25.537745, states[40]= 0.000693
Saving checkpoint... 
Iteration: 465403622, states[0] = -95.010668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479751410, states[0] = -94.912045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492392269, states[0] = -95.007241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505540525, states[0] = 15.449374, states[40]= 0.005268
Saving checkpoint... 
Iteration: 518058596, states[0] = 8.485130, states[40]= 0.004891
Saving checkpoint... 
Iteration: 529341839, states[0] = -94.986775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541316190, states[0] = -94.971892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553430240, states[0] = -95.017327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566388115, states[0] = -95.005854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578666287, states[0] = -93.231524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591364058, states[0] = -94.996954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603727026, states[0] = -94.877110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614931256, states[0] = -95.017514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627520174, states[0] = 21.456294, states[40]= 0.009687
Saving checkpoint... 
Iteration: 639882206, states[0] = -95.003808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652529496, states[0] = 19.101506, states[40]= 0.006223
Saving checkpoint... 
Iteration: 663925404, states[0] = -95.016159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675361884, states[0] = -94.995995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688360111, states[0] = -94.995233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701849810, states[0] = -94.990585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713766677, states[0] = -94.929744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724961405, states[0] = -95.023238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736644833, states[0] = -63.745901, states[40]= 0.000003
Saving checkpoint... 
Iteration: 748814351, states[0] = -94.970545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759358197, states[0] = -94.994361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772778807, states[0] = -94.942028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785381250, states[0] = -95.003383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798324493, states[0] = -94.976960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810924643, states[0] = -95.015889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823534326, states[0] = 17.589147, states[40]= 0.005662
Saving checkpoint... 
Iteration: 831181696, states[0] = -94.778814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843325921, states[0] = -94.977789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855513697, states[0] = 22.627654, states[40]= 0.023774
Saving checkpoint... 
Iteration: 867840329, states[0] = -94.985786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879212952, states[0] = -94.852830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889900432, states[0] = -95.009481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901807453, states[0] = -94.965681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913916065, states[0] = -95.013734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926633728, states[0] = -51.169361, states[40]= 0.000023
Saving checkpoint... 
Iteration: 939471362, states[0] = -95.024686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951006479, states[0] = 25.989012, states[40]= 0.116376
Saving checkpoint... 
Iteration: 962668472, states[0] = -93.975969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976094249, states[0] = -13.093392, states[40]= 0.001754
Saving checkpoint... 
Iteration: 987017699, states[0] = 21.935295, states[40]= 0.012555
Saving checkpoint... 
Iteration: 999769336, states[0] = -94.932397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013008026, states[0] = 24.462364, states[40]= 0.083701
Saving checkpoint... 
Iteration: 1025746277, states[0] = -94.905052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038671875, states[0] = -94.499340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050944967, states[0] = -95.020078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064340097, states[0] = -94.985543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076906775, states[0] = -95.011171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089091262, states[0] = -10.452268, states[40]= 0.002240
Saving checkpoint... 
Iteration: 1100265555, states[0] = -94.928282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112374873, states[0] = -95.000872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125203035, states[0] = -94.833942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137962337, states[0] = -95.023135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148923123, states[0] = -95.015320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161427342, states[0] = -95.016295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174830886, states[0] = -94.980471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187058132, states[0] = 8.676973, states[40]= 0.004898
Saving checkpoint... 
Iteration: 1198135938, states[0] = -53.567585, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1210651701, states[0] = -73.083750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1223486453, states[0] = -95.026642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236013253, states[0] = 22.706943, states[40]= 0.025949
Saving checkpoint... 
Iteration: 1249224549, states[0] = -94.872679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263052950, states[0] = 10.762691, states[40]= 0.004966
Saving checkpoint... 
Iteration: 1275443153, states[0] = -95.019583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289125435, states[0] = -42.502839, states[40]= 0.000091
Saving checkpoint... 
Iteration: 1298527035, states[0] = 19.803463, states[40]= 0.006673
Saving checkpoint... 
Iteration: 1312041348, states[0] = 15.152790, states[40]= 0.005233
Saving checkpoint... 
Iteration: 1324560001, states[0] = 7.899105, states[40]= 0.004870
Saving checkpoint... 
Iteration: 1336094674, states[0] = -13.477880, states[40]= 0.001692
Saving checkpoint... 
Iteration: 1349617766, states[0] = -35.013557, states[40]= 0.000264
Saving checkpoint... 
Iteration: 1361508113, states[0] = 24.402420, states[40]= 0.082064
Saving checkpoint... 
Iteration: 1373914096, states[0] = -95.012942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387812220, states[0] = -94.968707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398996402, states[0] = -95.027781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411149307, states[0] = -69.578886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1423383844, states[0] = -95.003885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434897101, states[0] = -95.008148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446755612, states[0] = -94.916631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458880140, states[0] = -95.002571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471894317, states[0] = -95.007272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483871643, states[0] = -94.999418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497662214, states[0] = -90.068672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509597442, states[0] = -95.251855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522030804, states[0] = -72.811720, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1530839669, states[0] = -95.221311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542701316, states[0] = -37.060446, states[40]= 0.000201
Saving checkpoint... 
Iteration: 1555862912, states[0] = 0.426816, states[40]= 0.004857
Saving checkpoint... 
Iteration: 1568469210, states[0] = -4.356341, states[40]= 0.003971
Saving checkpoint... 
Iteration: 1580517883, states[0] = -57.317343, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1592450243, states[0] = 7.723579, states[40]= 0.005608
Saving checkpoint... 
Iteration: 1603362114, states[0] = -95.096778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615604821, states[0] = -41.949867, states[40]= 0.000101
Saving checkpoint... 
Iteration: 1628467980, states[0] = -3.596269, states[40]= 0.004141
Saving checkpoint... 
Iteration: 1640232089, states[0] = -78.846390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651825784, states[0] = 19.075433, states[40]= 0.008088
Saving checkpoint... 
Iteration: 1663993070, states[0] = -95.174240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673100573, states[0] = 23.898437, states[40]= 0.000819
Saving checkpoint... 
Iteration: 1684325040, states[0] = -67.282013, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1696064731, states[0] = -95.107772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1707590182, states[0] = -95.294426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720084903, states[0] = -95.157397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732738516, states[0] = -95.246408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1745426090, states[0] = 18.953509, states[40]= 0.007999
Saving checkpoint... 
Iteration: 1758401385, states[0] = -38.215536, states[40]= 0.000172
Saving checkpoint... 
Iteration: 1772548166, states[0] = -94.797317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1781693855, states[0] = -95.296951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794501185, states[0] = -95.190094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807460978, states[0] = -95.072399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820761188, states[0] = -94.958692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833420139, states[0] = -95.039258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846468675, states[0] = -95.040776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857831327, states[0] = -94.992521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869755252, states[0] = -94.924616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880708511, states[0] = -94.850283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892484095, states[0] = -95.030234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903420596, states[0] = -95.017358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915591508, states[0] = -10.780020, states[40]= 0.002177
Saving checkpoint... 
Iteration: 1928209580, states[0] = -94.847467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939796482, states[0] = -94.957782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950098614, states[0] = -17.151440, states[40]= 0.001211
Saving checkpoint... 
Iteration: 1963606101, states[0] = -24.107418, states[40]= 0.000759
Saving checkpoint... 
Iteration: 1976358059, states[0] = -94.993857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990575818, states[0] = 0.376207, states[40]= 0.004302
Saving checkpoint... 
Iteration: 2003457590, states[0] = -95.021907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016210864, states[0] = -94.848349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029954770, states[0] = -95.021307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041750325, states[0] = -94.909689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052740921, states[0] = -94.897076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065697497, states[0] = -94.822267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078275815, states[0] = -94.938276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090127391, states[0] = -44.492759, states[40]= 0.000067
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.903598
 - CaMKt in component CaMK (millimolar): 0.006980
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.583611
 - nass in component intracellular_ions (millimolar): 6.583671
 - ki in component intracellular_ions (millimolar): 145.394165
 - kss in component intracellular_ions (millimolar): 145.394146
 - cansr in component intracellular_ions (millimolar): 1.311768
 - cajsr in component intracellular_ions (millimolar): 1.273669
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003618
 - hf in component INa (dimensionless): 0.880031
 - hs in component INa (dimensionless): 0.880026
 - j in component INa (dimensionless): 0.879998
 - hsp in component INa (dimensionless): 0.725887
 - jp in component INa (dimensionless): 0.879978
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709632
 - hLp in component INaL (dimensionless): 0.451076
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.619688
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.694200
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933973
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001603
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335270
 - xs1 in component IKs (dimensionless): 0.244017
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:40:01 (7788): called boinc_finish(0)

</stderr_txt>
]]>


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