𝕏

Task 55498661

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_503_0
Workunit 26350452
Created 1 Jul 2024, 14:44:34 UTC
Sent 1 Jul 2024, 15:16:48 UTC
Report deadline 4 Jul 2024, 15:16:48 UTC
Received 2 Jul 2024, 1:33:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233433
Run time 2 hours 16 min 24 sec
CPU time 2 hours 3 min 59 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.67 MB
Peak swap size 32.60 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_503.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_503_0_r1036213888_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_503_0_r1036213888_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 102.104359
     * GNaL_b in INaL: 0.006123
     * Gto_b in Ito: 0.085913
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031926
     * GKs_b in IKs: 0.001961
     * GK1_b in IK1: 0.161227
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.780492
     * GKb_b in IKb: 0.003817
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036008
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11886067, states[0] = -86.791230, states[40]= 0.000001
Saving checkpoint... 
Iteration: 16908747, states[0] = -86.821991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 26810457, states[0] = -86.675444, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_503.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_503_0_r1036213888_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-BASE_MID-conf_503_0_r1036213888_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 102.104359
     * GNaL_b in INaL: 0.006123
     * Gto_b in Ito: 0.085913
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031926
     * GKs_b in IKs: 0.001961
     * GK1_b in IK1: 0.161227
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.780492
     * GKb_b in IKb: 0.003817
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036008
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 26810457
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.675444 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 40402470, states[0] = -86.863701, states[40]= 0.000002
Saving checkpoint... 
Iteration: 49873349, states[0] = -86.846445, states[40]= 0.000002
Saving checkpoint... 
Iteration: 61204366, states[0] = -85.268045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73343230, states[0] = -86.825733, states[40]= 0.000002
Saving checkpoint... 
Iteration: 83118065, states[0] = -4.083644, states[40]= 0.000152
Saving checkpoint... 
Iteration: 95563655, states[0] = 22.273184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 105965372, states[0] = -86.968436, states[40]= 0.000002
Saving checkpoint... 
Iteration: 115283658, states[0] = -86.680788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 124839205, states[0] = -86.839609, states[40]= 0.000002
Saving checkpoint... 
Iteration: 133981012, states[0] = -86.980262, states[40]= 0.000002
Saving checkpoint... 
Iteration: 142737132, states[0] = -86.440224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 152895999, states[0] = -86.924663, states[40]= 0.000002
Saving checkpoint... 
Iteration: 164692113, states[0] = -79.289473, states[40]= 0.000002
Saving checkpoint... 
Iteration: 175022892, states[0] = 31.565568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186770217, states[0] = -86.628011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 197910637, states[0] = -86.938144, states[40]= 0.000002
Saving checkpoint... 
Iteration: 208355035, states[0] = -86.869715, states[40]= 0.000002
Saving checkpoint... 
Iteration: 219896887, states[0] = -86.924139, states[40]= 0.000002
Saving checkpoint... 
Iteration: 231896476, states[0] = -86.923131, states[40]= 0.000002
Saving checkpoint... 
Iteration: 242969711, states[0] = -86.973954, states[40]= 0.000002
Saving checkpoint... 
Iteration: 254312831, states[0] = -86.777098, states[40]= 0.000002
Saving checkpoint... 
Iteration: 264784111, states[0] = -86.682926, states[40]= 0.000001
Saving checkpoint... 
Iteration: 275334931, states[0] = -86.828772, states[40]= 0.000002
Saving checkpoint... 
Iteration: 286656171, states[0] = -36.779710, states[40]= 0.000410
Saving checkpoint... 
Iteration: 297982552, states[0] = -86.976218, states[40]= 0.000002
Saving checkpoint... 
Iteration: 309060243, states[0] = 23.318379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320226135, states[0] = -86.353195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331369994, states[0] = -86.885644, states[40]= 0.000002
Saving checkpoint... 
Iteration: 342717223, states[0] = -86.277301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353943953, states[0] = -86.954050, states[40]= 0.000002
Saving checkpoint... 
Iteration: 364702625, states[0] = -85.835561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376090668, states[0] = 10.282686, states[40]= 0.000019
Saving checkpoint... 
Iteration: 386981699, states[0] = -86.970634, states[40]= 0.000002
Saving checkpoint... 
Iteration: 396952630, states[0] = -86.956499, states[40]= 0.000002
Saving checkpoint... 
Iteration: 408192202, states[0] = -79.642144, states[40]= 0.000002
Saving checkpoint... 
Iteration: 417934687, states[0] = -86.944351, states[40]= 0.000002
Saving checkpoint... 
Iteration: 429086792, states[0] = 12.120856, states[40]= 0.000012
Saving checkpoint... 
Iteration: 439662461, states[0] = -42.678217, states[40]= 0.000247
Saving checkpoint... 
Iteration: 450595935, states[0] = 7.702210, states[40]= 0.000032
Saving checkpoint... 
Iteration: 461808618, states[0] = -86.753035, states[40]= 0.000002
Saving checkpoint... 
Iteration: 472439460, states[0] = -86.944263, states[40]= 0.000002
Saving checkpoint... 
Iteration: 483798414, states[0] = -86.720566, states[40]= 0.000001
Saving checkpoint... 
Iteration: 495652907, states[0] = -33.864024, states[40]= 0.000488
Saving checkpoint... 
Iteration: 507305968, states[0] = -86.742575, states[40]= 0.000002
Saving checkpoint... 
Iteration: 518730861, states[0] = -86.376817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529269188, states[0] = -86.603618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 539908851, states[0] = -86.917008, states[40]= 0.000002
Saving checkpoint... 
Iteration: 550947454, states[0] = -86.944466, states[40]= 0.000002
Saving checkpoint... 
Iteration: 564051456, states[0] = 26.357150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575000218, states[0] = -60.179642, states[40]= 0.000003
Saving checkpoint... 
Iteration: 584047751, states[0] = 27.495758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593679204, states[0] = -60.674968, states[40]= 0.000028
Saving checkpoint... 
Iteration: 603934397, states[0] = -86.933166, states[40]= 0.000002
Saving checkpoint... 
Iteration: 614261778, states[0] = -86.562354, states[40]= 0.000001
Saving checkpoint... 
Iteration: 623061428, states[0] = 22.885548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633253412, states[0] = -86.516213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642422584, states[0] = -86.922367, states[40]= 0.000002
Saving checkpoint... 
Iteration: 652442991, states[0] = -86.935801, states[40]= 0.000002
Saving checkpoint... 
Iteration: 662407125, states[0] = -86.908185, states[40]= 0.000002
Saving checkpoint... 
Iteration: 675141792, states[0] = -24.712000, states[40]= 0.000431
Saving checkpoint... 
Iteration: 687356286, states[0] = -86.843786, states[40]= 0.000002
Saving checkpoint... 
Iteration: 699920048, states[0] = -86.917001, states[40]= 0.000002
Saving checkpoint... 
Iteration: 713056509, states[0] = 24.668480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726431486, states[0] = -86.923924, states[40]= 0.000002
Saving checkpoint... 
Iteration: 739798944, states[0] = -86.706913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 753165425, states[0] = -45.577508, states[40]= 0.000182
Saving checkpoint... 
Iteration: 766855383, states[0] = -86.837583, states[40]= 0.000002
Saving checkpoint... 
Iteration: 780646849, states[0] = -28.737028, states[40]= 0.000535
Saving checkpoint... 
Iteration: 789864854, states[0] = -86.851006, states[40]= 0.000002
Saving checkpoint... 
Iteration: 799157176, states[0] = -37.645501, states[40]= 0.000382
Saving checkpoint... 
Iteration: 809421218, states[0] = -86.911414, states[40]= 0.000002
Saving checkpoint... 
Iteration: 820494980, states[0] = -86.949881, states[40]= 0.000002
Saving checkpoint... 
Iteration: 831987367, states[0] = -86.946527, states[40]= 0.000002
Saving checkpoint... 
Iteration: 846715663, states[0] = -86.231151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861696493, states[0] = -83.847186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 876698381, states[0] = -84.816900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891723185, states[0] = -86.294598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906542555, states[0] = 28.927279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921187694, states[0] = -72.586617, states[40]= 0.000005
Saving checkpoint... 
Iteration: 935622584, states[0] = -8.759471, states[40]= 0.000184
Saving checkpoint... 
Iteration: 950216757, states[0] = -86.235381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965101333, states[0] = 4.949240, states[40]= 0.000053
Saving checkpoint... 
Iteration: 979877067, states[0] = -86.856603, states[40]= 0.000002
Saving checkpoint... 
Iteration: 994636912, states[0] = -20.808151, states[40]= 0.000279
Saving checkpoint... 
Iteration: 1009333961, states[0] = -86.782986, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1024136696, states[0] = -20.630803, states[40]= 0.000273
Saving checkpoint... 
Iteration: 1038373057, states[0] = -86.847834, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1051330673, states[0] = -86.773356, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1063671221, states[0] = -51.543556, states[40]= 0.000091
Saving checkpoint... 
Iteration: 1074390677, states[0] = -86.867246, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1085594624, states[0] = 8.376730, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1096892921, states[0] = -86.868351, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1108060303, states[0] = 23.315089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119147787, states[0] = -29.473020, states[40]= 0.000537
Saving checkpoint... 
Iteration: 1129876956, states[0] = -86.847554, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1140770592, states[0] = -86.573160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1151730645, states[0] = -86.336425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162684314, states[0] = -67.371912, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1173105430, states[0] = 2.741340, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1184316727, states[0] = -86.731979, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1195381888, states[0] = -86.849874, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1206472524, states[0] = -86.918462, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1217532721, states[0] = 30.931462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228627597, states[0] = -12.940749, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1239630923, states[0] = -15.793737, states[40]= 0.000190
Saving checkpoint... 
Iteration: 1250812874, states[0] = -86.717706, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1262056363, states[0] = 24.732570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272882850, states[0] = -86.846420, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1283162897, states[0] = -43.006317, states[40]= 0.000236
Saving checkpoint... 
Iteration: 1294133802, states[0] = -18.225646, states[40]= 0.000216
Saving checkpoint... 
Iteration: 1305203186, states[0] = -85.818478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316294773, states[0] = -86.658505, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1327203482, states[0] = -85.845187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338116649, states[0] = -4.214338, states[40]= 0.000158
Saving checkpoint... 
Iteration: 1349045694, states[0] = 28.103673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360125791, states[0] = -11.388819, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1371061898, states[0] = 22.727160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381170774, states[0] = -51.024145, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1392103172, states[0] = 3.986338, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1402939392, states[0] = -86.889199, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1413874062, states[0] = -86.826915, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1424963660, states[0] = -86.901494, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1435934063, states[0] = -86.883767, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1446947691, states[0] = -86.891688, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1457964321, states[0] = -86.899856, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1468873159, states[0] = -86.822446, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1479969993, states[0] = -86.901193, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1490671698, states[0] = -51.994447, states[40]= 0.000086
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.787306
 - CaMKt in component CaMK (millimolar): 0.025406
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.070799
 - nass in component intracellular_ions (millimolar): 8.070954
 - ki in component intracellular_ions (millimolar): 143.289108
 - kss in component intracellular_ions (millimolar): 143.289069
 - cansr in component intracellular_ions (millimolar): 2.073840
 - cajsr in component intracellular_ions (millimolar): 2.010517
 - cai in component intracellular_ions (millimolar): 0.000097
 - m in component INa (dimensionless): 0.008195
 - hf in component INa (dimensionless): 0.659063
 - hs in component INa (dimensionless): 0.659033
 - j in component INa (dimensionless): 0.658857
 - hsp in component INa (dimensionless): 0.410947
 - jp in component INa (dimensionless): 0.658731
 - mL in component INaL (dimensionless): 0.000232
 - hL in component INaL (dimensionless): 0.455343
 - hLp in component INaL (dimensionless): 0.221667
 - a in component Ito (dimensionless): 0.001077
 - iF in component Ito (dimensionless): 0.999460
 - iS in component Ito (dimensionless): 0.533963
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999460
 - iSp in component Ito (dimensionless): 0.577519
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.877338
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999618
 - jca in component ICaL (dimensionless): 0.999940
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003942
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.508738
 - xs1 in component IKs (dimensionless): 0.333510
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997034
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
20:47:18 (93366): called boinc_finish(0)

</stderr_txt>
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