Task 55495001

Name	HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_70-conf_2_0
Workunit	26348626
Created	1 Jul 2024, 14:42:46 UTC
Sent	1 Jul 2024, 14:59:26 UTC
Report deadline	4 Jul 2024, 14:59:26 UTC
Received	3 Jul 2024, 7:32:58 UTC
Server state	Over
Outcome	Success
Client state	Done
Exit status	0 (0x00000000)
Computer ID	237903
Run time	1 hours 46 min 59 sec
CPU time	43 min 50 sec
Validate state	Valid
Credit	44.66
Device peak FLOPS	5.42 GFLOPS
Application version	Human ventricular cell models optimization v0.02 windows_x86_64
Peak working set size	10.16 MB
Peak swap size	5.32 MB
Peak disk usage	0.02 MB
Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_70-conf_2.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_70-conf_2_0_r1472688380_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_70-conf_2_0_r1472688380_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.224249
     * GNaL_b in INaL: 0.005816
     * Gto_b in Ito: 0.083357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009696
     * GKs_b in IKs: 0.001913
     * GK1_b in IK1: 0.161300
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.592112
     * GKb_b in IKb: 0.003775
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030098
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13411093, states[0] = -94.861551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26167192, states[0] = -22.543247, states[40]= 0.004840
Saving checkpoint... 
Iteration: 35795258, states[0] = -93.712553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69173759, states[0] = -22.421536, states[40]= 0.005095
Saving checkpoint... 
Iteration: 84566586, states[0] = 18.286515, states[40]= 0.004558
Saving checkpoint... 
Iteration: 101883656, states[0] = -94.706422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114864282, states[0] = -94.680600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129550149, states[0] = 23.388931, states[40]= 0.003712
Saving checkpoint... 
Iteration: 144273868, states[0] = -59.468715, states[40]= 0.000045
Saving checkpoint... 
Iteration: 160469784, states[0] = -94.757996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176995281, states[0] = -94.766981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194868868, states[0] = -94.678813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207939426, states[0] = -94.740386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229620812, states[0] = -0.321396, states[40]= 0.004686
Saving checkpoint... 
Iteration: 243795881, states[0] = -77.913522, states[40]= 0.000002
Saving checkpoint... 
Iteration: 257722840, states[0] = -36.640944, states[40]= 0.001597
Saving checkpoint... 
Iteration: 271282295, states[0] = -64.273923, states[40]= 0.000020
Saving checkpoint... 
Iteration: 285843932, states[0] = -94.642470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299197304, states[0] = -28.267027, states[40]= 0.003973
Saving checkpoint... 
Iteration: 313264564, states[0] = -53.964014, states[40]= 0.000117
Saving checkpoint... 
Iteration: 329768347, states[0] = -55.865519, states[40]= 0.000084
Saving checkpoint... 
Iteration: 344685162, states[0] = -24.688474, states[40]= 0.004897
Saving checkpoint... 
Iteration: 358125016, states[0] = -1.974658, states[40]= 0.004432
Saving checkpoint... 
Iteration: 372202573, states[0] = -29.875696, states[40]= 0.003452
Saving checkpoint... 
Iteration: 387066774, states[0] = 18.501669, states[40]= 0.004598
Saving checkpoint... 
Iteration: 398843584, states[0] = -94.641513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414862676, states[0] = -94.669151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428243018, states[0] = -44.347467, states[40]= 0.000550
Saving checkpoint... 
Iteration: 443956751, states[0] = -94.748481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457196673, states[0] = -28.071623, states[40]= 0.004034
Saving checkpoint... 
Iteration: 471142632, states[0] = -9.503112, states[40]= 0.002933
Saving checkpoint... 
Iteration: 485746906, states[0] = -45.966530, states[40]= 0.000430
Saving checkpoint... 
Iteration: 501967376, states[0] = -94.753411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517969413, states[0] = -94.754285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532694933, states[0] = -27.550730, states[40]= 0.004194
Saving checkpoint... 
Iteration: 549680751, states[0] = -23.402822, states[40]= 0.005063
Saving checkpoint... 
Iteration: 562152482, states[0] = -13.782519, states[40]= 0.002662
Saving checkpoint... 
Iteration: 576218092, states[0] = -34.956239, states[40]= 0.001971
Saving checkpoint... 
Iteration: 594398675, states[0] = -94.708330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611653463, states[0] = -14.190866, states[40]= 0.002702
Saving checkpoint... 
Iteration: 625791908, states[0] = -72.831977, states[40]= 0.000005
Saving checkpoint... 
Iteration: 641832368, states[0] = -94.620649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656781571, states[0] = -63.716221, states[40]= 0.000022
Saving checkpoint... 
Iteration: 669063422, states[0] = 19.530334, states[40]= 0.004449
Saving checkpoint... 
Iteration: 684168476, states[0] = -19.684171, states[40]= 0.004600
Saving checkpoint... 
Iteration: 698040278, states[0] = 26.320704, states[40]= 0.003236
Saving checkpoint... 
Iteration: 711965390, states[0] = -94.752010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721587957, states[0] = 11.593538, states[40]= 0.005146
Saving checkpoint... 
Iteration: 736843046, states[0] = -94.639840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750395438, states[0] = -94.704971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756435028, states[0] = -94.735524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764932601, states[0] = -94.733965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781764915, states[0] = -54.126489, states[40]= 0.000114
Saving checkpoint... 
Iteration: 795523110, states[0] = 30.479016, states[40]= 0.003314
Saving checkpoint... 
Iteration: 809032199, states[0] = 28.520968, states[40]= 0.002965
Saving checkpoint... 
Iteration: 827265822, states[0] = -54.576069, states[40]= 0.000105


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_70-conf_2.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_70-conf_2_0_r1472688380_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_70-conf_2_0_r1472688380_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.224249
     * GNaL_b in INaL: 0.005816
     * Gto_b in Ito: 0.083357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009696
     * GKs_b in IKs: 0.001913
     * GK1_b in IK1: 0.161300
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.592112
     * GKb_b in IKb: 0.003775
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030098
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 827265822
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -54.576069 (After loading)
 - states[40]: 0.000105 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 860849113, states[0] = -94.648986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875433717, states[0] = -94.734418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888797825, states[0] = -80.524028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 902206629, states[0] = -31.152029, states[40]= 0.003041
Saving checkpoint... 
Iteration: 916214413, states[0] = -33.702748, states[40]= 0.002290
Saving checkpoint... 
Iteration: 930212389, states[0] = -33.026606, states[40]= 0.002477
Saving checkpoint... 
Iteration: 944554525, states[0] = 22.188656, states[40]= 0.003987
Saving checkpoint... 
Iteration: 961786197, states[0] = -67.281251, states[40]= 0.000012
Saving checkpoint... 
Iteration: 975430868, states[0] = -94.732347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989869452, states[0] = -94.676401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002294381, states[0] = -75.782620, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1017476061, states[0] = -94.755960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030895513, states[0] = -94.704381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044508158, states[0] = 30.992179, states[40]= 0.082646
Saving checkpoint... 
Iteration: 1060009001, states[0] = 30.895253, states[40]= 0.063332
Saving checkpoint... 
Iteration: 1076767494, states[0] = -55.418632, states[40]= 0.000091
Saving checkpoint... 
Iteration: 1091011085, states[0] = 30.937195, states[40]= 0.033140
Saving checkpoint... 
Iteration: 1102913225, states[0] = -94.719414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117684395, states[0] = -24.463194, states[40]= 0.004934
Saving checkpoint... 
Iteration: 1134077276, states[0] = 15.162973, states[40]= 0.004951
Saving checkpoint... 
Iteration: 1147594629, states[0] = 9.292031, states[40]= 0.005195
Saving checkpoint... 
Iteration: 1161269484, states[0] = -56.449298, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1179028795, states[0] = 29.349440, states[40]= 0.002937
Saving checkpoint... 
Iteration: 1193678851, states[0] = -22.845145, states[40]= 0.005096
Saving checkpoint... 
Iteration: 1210355448, states[0] = -94.657406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215420288, states[0] = -94.724481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230720473, states[0] = -35.783066, states[40]= 0.001779
Saving checkpoint... 
Iteration: 1242767304, states[0] = -55.321258, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1255189959, states[0] = -26.082622, states[40]= 0.004601
Saving checkpoint... 
Iteration: 1271449999, states[0] = -94.743017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284060851, states[0] = 20.308393, states[40]= 0.004324
Saving checkpoint... 
Iteration: 1298867042, states[0] = -94.672676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317297034, states[0] = -79.372468, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1332469086, states[0] = -94.752225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346927174, states[0] = -94.729013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359277633, states[0] = -61.098086, states[40]= 0.000034


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_70-conf_2.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_70-conf_2_0_r1472688380_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-TESZT_Block_Kr_70-conf_2_0_r1472688380_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.224249
     * GNaL_b in INaL: 0.005816
     * Gto_b in Ito: 0.083357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009696
     * GKs_b in IKs: 0.001913
     * GK1_b in IK1: 0.161300
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.592112
     * GKb_b in IKb: 0.003775
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030098
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1359277633
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -61.098086 (After loading)
 - states[40]: 0.000034 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1389213289, states[0] = -33.325462, states[40]= 0.002393
Saving checkpoint... 
Iteration: 1401083845, states[0] = 12.986075, states[40]= 0.005089
Saving checkpoint... 
Iteration: 1413377937, states[0] = -94.685382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424518527, states[0] = 31.028002, states[40]= 0.005274
Saving checkpoint... 
Iteration: 1441049253, states[0] = 23.732150, states[40]= 0.003692
Saving checkpoint... 
Iteration: 1455660227, states[0] = -16.848615, states[40]= 0.003381
Saving checkpoint... 
Iteration: 1464454255, states[0] = -94.744807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480755217, states[0] = -49.579084, states[40]= 0.000243
Saving checkpoint... 
Iteration: 1495100098, states[0] = 7.367862, states[40]= 0.005193
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.639520
 - CaMKt in component CaMK (millimolar): 0.015293
 - cass in component intracellular_ions (millimolar): 0.000084
 - nai in component intracellular_ions (millimolar): 6.264256
 - nass in component intracellular_ions (millimolar): 6.264335
 - ki in component intracellular_ions (millimolar): 145.651445
 - kss in component intracellular_ions (millimolar): 145.651436
 - cansr in component intracellular_ions (millimolar): 1.563914
 - cajsr in component intracellular_ions (millimolar): 1.495380
 - cai in component intracellular_ions (millimolar): 0.000085
 - m in component INa (dimensionless): 0.003716
 - hf in component INa (dimensionless): 0.875374
 - hs in component INa (dimensionless): 0.875360
 - j in component INa (dimensionless): 0.875274
 - hsp in component INa (dimensionless): 0.717118
 - jp in component INa (dimensionless): 0.875154
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.629204
 - hLp in component INaL (dimensionless): 0.317263
 - a in component Ito (dimensionless): 0.000635
 - iF in component Ito (dimensionless): 0.999863
 - iS in component Ito (dimensionless): 0.465524
 - ap in component Ito (dimensionless): 0.000323
 - iFp in component Ito (dimensionless): 0.999864
 - iSp in component Ito (dimensionless): 0.517522
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.848093
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999000
 - jca in component ICaL (dimensionless): 0.999828
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002602
 - xrf in component IKr (dimensionless): 0.000007
 - xrs in component IKr (dimensionless): 0.527991
 - xs1 in component IKs (dimensionless): 0.367444
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997406
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:14:38 (15764): called boinc_finish(0)

</stderr_txt>
]]>