𝕏

Task 55473664

Name HuVeMOp_20240701162112100363_ORdGradInc_k_26-Pieske_333-conf_393_0
Workunit 26337977
Created 1 Jul 2024, 14:25:24 UTC
Sent 1 Jul 2024, 14:25:30 UTC
Report deadline 4 Jul 2024, 14:25:30 UTC
Received 1 Jul 2024, 23:04:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226666
Run time 2 hours 48 min 57 sec
CPU time 2 hours 40 min 41 sec
Validate state Valid
Credit 42.68
Device peak FLOPS 2.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
aarch64-unknown-linux-gnu
Peak working set size 2.20 MB
Peak swap size 10.95 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-Pieske_333-conf_393.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-Pieske_333-conf_393_0_r1753215444_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-Pieske_333-conf_393_0_r1753215444_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.793632
     * GNaL_b in INaL: 0.006008
     * Gto_b in Ito: 0.084383
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031468
     * GKs_b in IKs: 0.001893
     * GK1_b in IK1: 0.161575
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.655673
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031089
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10162583, states[0] = -87.820806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20039675, states[0] = 5.342982, states[40]= 0.006792
Saving checkpoint... 
Iteration: 30047961, states[0] = -3.019117, states[40]= 0.005244
Saving checkpoint... 
Iteration: 40152197, states[0] = -87.787360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49727186, states[0] = -22.249717, states[40]= 0.001035
Saving checkpoint... 
Iteration: 59899421, states[0] = -31.433298, states[40]= 0.000453
Saving checkpoint... 
Iteration: 69858421, states[0] = 12.021236, states[40]= 0.007855
Saving checkpoint... 
Iteration: 79920923, states[0] = -64.876916, states[40]= 0.000004
Saving checkpoint... 
Iteration: 90003250, states[0] = 21.726671, states[40]= 0.029925
Saving checkpoint... 
Iteration: 100014598, states[0] = 16.335996, states[40]= 0.009133
Saving checkpoint... 
Iteration: 109968149, states[0] = -87.761262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119946782, states[0] = -87.659955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129941744, states[0] = -87.595612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139900169, states[0] = -43.547355, states[40]= 0.000099
Saving checkpoint... 
Iteration: 150040837, states[0] = -9.104771, states[40]= 0.003544
Saving checkpoint... 
Iteration: 159976098, states[0] = -87.804320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170159190, states[0] = 22.880588, states[40]= 0.051543
Saving checkpoint... 
Iteration: 180215872, states[0] = -24.915394, states[40]= 0.000828
Saving checkpoint... 
Iteration: 190086699, states[0] = -81.600620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199913767, states[0] = -73.159649, states[40]= 0.000001
Saving checkpoint... 
Iteration: 209856978, states[0] = 2.825182, states[40]= 0.006554
Saving checkpoint... 
Iteration: 219560690, states[0] = -46.071734, states[40]= 0.000069
Saving checkpoint... 
Iteration: 228655775, states[0] = 21.824166, states[40]= 0.031504
Saving checkpoint... 
Iteration: 237885146, states[0] = -36.420998, states[40]= 0.000257
Saving checkpoint... 
Iteration: 247131300, states[0] = -87.795895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256169071, states[0] = 14.433095, states[40]= 0.008388
Saving checkpoint... 
Iteration: 265374163, states[0] = -25.107134, states[40]= 0.000815
Saving checkpoint... 
Iteration: 274353627, states[0] = 0.033672, states[40]= 0.006035
Saving checkpoint... 
Iteration: 283638407, states[0] = -74.764739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293105663, states[0] = -87.719454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302284902, states[0] = -87.771323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311442563, states[0] = -87.741747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320725367, states[0] = -57.636737, states[40]= 0.000012
Saving checkpoint... 
Iteration: 329692240, states[0] = -12.749191, states[40]= 0.002554
Saving checkpoint... 
Iteration: 338710202, states[0] = -38.884652, states[40]= 0.000188
Saving checkpoint... 
Iteration: 348672968, states[0] = 5.635459, states[40]= 0.006972
Saving checkpoint... 
Iteration: 358254922, states[0] = -87.644631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368173189, states[0] = 3.905853, states[40]= 0.006724
Saving checkpoint... 
Iteration: 378161602, states[0] = 11.553785, states[40]= 0.007780
Saving checkpoint... 
Iteration: 388132670, states[0] = 27.971201, states[40]= 0.121057
Saving checkpoint... 
Iteration: 398069582, states[0] = -85.198926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408152961, states[0] = 14.953042, states[40]= 0.008548
Saving checkpoint... 
Iteration: 418036813, states[0] = -40.535929, states[40]= 0.000151
Saving checkpoint... 
Iteration: 427513408, states[0] = -9.528581, states[40]= 0.003420
Saving checkpoint... 
Iteration: 436769457, states[0] = -87.764056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446069365, states[0] = -86.991909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455407946, states[0] = -87.559845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465682270, states[0] = -17.824045, states[40]= 0.001555
Saving checkpoint... 
Iteration: 475019137, states[0] = -24.098670, states[40]= 0.000887


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-Pieske_333-conf_393.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-Pieske_333-conf_393_0_r1753215444_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-Pieske_333-conf_393_0_r1753215444_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.793632
     * GNaL_b in INaL: 0.006008
     * Gto_b in Ito: 0.084383
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031468
     * GKs_b in IKs: 0.001893
     * GK1_b in IK1: 0.161575
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.655673
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031089
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 475019137
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -24.098670 (After loading)
 - states[40]: 0.000887 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 485854738, states[0] = -28.747782, states[40]= 0.000591
Saving checkpoint... 
Iteration: 496868681, states[0] = -49.406588, states[40]= 0.000042
Saving checkpoint... 
Iteration: 507680036, states[0] = -20.592140, states[40]= 0.001202
Saving checkpoint... 
Iteration: 518380307, states[0] = -70.376947, states[40]= 0.000002
Saving checkpoint... 
Iteration: 528599640, states[0] = -87.784413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538665420, states[0] = -5.123104, states[40]= 0.004727
Saving checkpoint... 
Iteration: 548568433, states[0] = -87.633019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558801013, states[0] = 16.865334, states[40]= 0.009455
Saving checkpoint... 
Iteration: 568997431, states[0] = -7.185925, states[40]= 0.004115
Saving checkpoint... 
Iteration: 578982604, states[0] = 6.147170, states[40]= 0.007040
Saving checkpoint... 
Iteration: 589232748, states[0] = -87.655629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599565460, states[0] = -87.659984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609822298, states[0] = -2.177746, states[40]= 0.005527
Saving checkpoint... 
Iteration: 620036157, states[0] = -69.278190, states[40]= 0.000002
Saving checkpoint... 
Iteration: 630285711, states[0] = 20.517373, states[40]= 0.017883
Saving checkpoint... 
Iteration: 640823575, states[0] = -7.182733, states[40]= 0.004116
Saving checkpoint... 
Iteration: 650614798, states[0] = 21.358020, states[40]= 0.025218
Saving checkpoint... 
Iteration: 660547655, states[0] = -86.939705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670507512, states[0] = -35.017381, states[40]= 0.000305
Saving checkpoint... 
Iteration: 680420314, states[0] = -87.792418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690354493, states[0] = -56.791591, states[40]= 0.000014
Saving checkpoint... 
Iteration: 700540149, states[0] = -85.689939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710594891, states[0] = -87.824060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720724307, states[0] = -87.692506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730911883, states[0] = -87.781351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740947197, states[0] = 17.986327, states[40]= 0.010466
Saving checkpoint... 
Iteration: 751081083, states[0] = -87.795805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761030444, states[0] = -82.636870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770996599, states[0] = -33.837428, states[40]= 0.000349
Saving checkpoint... 
Iteration: 780980003, states[0] = -12.145446, states[40]= 0.002704
Saving checkpoint... 
Iteration: 790963703, states[0] = 4.343061, states[40]= 0.006789
Saving checkpoint... 
Iteration: 800998013, states[0] = -39.852265, states[40]= 0.000165
Saving checkpoint... 
Iteration: 810844448, states[0] = -59.763657, states[40]= 0.000009
Saving checkpoint... 
Iteration: 820912722, states[0] = -87.811433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830865036, states[0] = -87.135431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840926698, states[0] = 22.300259, states[40]= 0.039727
Saving checkpoint... 
Iteration: 851033168, states[0] = -87.476026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861060433, states[0] = -87.763751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871033658, states[0] = -87.578395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881215542, states[0] = -87.727255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891397964, states[0] = -87.788008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901477337, states[0] = -25.282237, states[40]= 0.000803
Saving checkpoint... 
Iteration: 911469246, states[0] = -15.330364, states[40]= 0.001985
Saving checkpoint... 
Iteration: 921572480, states[0] = -87.820156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931544688, states[0] = -87.730697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941471505, states[0] = -22.725297, states[40]= 0.000997
Saving checkpoint... 
Iteration: 951570625, states[0] = -87.823232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961594863, states[0] = 16.450687, states[40]= 0.009198
Saving checkpoint... 
Iteration: 971549784, states[0] = -87.765020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981630644, states[0] = -17.789123, states[40]= 0.001561
Saving checkpoint... 
Iteration: 991654933, states[0] = -52.805757, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1001735125, states[0] = 39.209752, states[40]= 0.082699
Saving checkpoint... 
Iteration: 1011902086, states[0] = 32.782549, states[40]= 0.121353
Saving checkpoint... 
Iteration: 1021866540, states[0] = -87.720238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031881231, states[0] = -87.779095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042027282, states[0] = -87.701792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052066110, states[0] = 28.347422, states[40]= 0.122687
Saving checkpoint... 
Iteration: 1062085985, states[0] = 15.826040, states[40]= 0.008883
Saving checkpoint... 
Iteration: 1072064538, states[0] = 27.398160, states[40]= 0.117838
Saving checkpoint... 
Iteration: 1081756038, states[0] = 12.723316, states[40]= 0.007988
Saving checkpoint... 
Iteration: 1091436326, states[0] = 2.090491, states[40]= 0.006430
Saving checkpoint... 
Iteration: 1101026299, states[0] = -87.724607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110571920, states[0] = 20.160127, states[40]= 0.015908
Saving checkpoint... 
Iteration: 1119991762, states[0] = -78.799841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129447855, states[0] = -15.906557, states[40]= 0.001876
Saving checkpoint... 
Iteration: 1139107166, states[0] = -7.295231, states[40]= 0.004082
Saving checkpoint... 
Iteration: 1148732943, states[0] = 20.869945, states[40]= 0.020420
Saving checkpoint... 
Iteration: 1158343281, states[0] = -87.662942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167797029, states[0] = -43.093086, states[40]= 0.000106
Saving checkpoint... 
Iteration: 1177413318, states[0] = 12.610754, states[40]= 0.007967
Saving checkpoint... 
Iteration: 1187003260, states[0] = -87.608033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196521667, states[0] = -87.744278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206070590, states[0] = 16.356775, states[40]= 0.009145
Saving checkpoint... 
Iteration: 1215611930, states[0] = -24.369517, states[40]= 0.000867
Saving checkpoint... 
Iteration: 1225206513, states[0] = -87.813600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234682886, states[0] = -87.737879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244144365, states[0] = -76.091378, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1253559565, states[0] = 19.356855, states[40]= 0.012965
Saving checkpoint... 
Iteration: 1263120280, states[0] = -42.339493, states[40]= 0.000118
Saving checkpoint... 
Iteration: 1272448631, states[0] = -36.816035, states[40]= 0.000245
Saving checkpoint... 
Iteration: 1281988401, states[0] = -87.354227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291546005, states[0] = 23.466347, states[40]= 0.064057
Saving checkpoint... 
Iteration: 1301007155, states[0] = -87.727962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310657393, states[0] = -87.604234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320116883, states[0] = -45.511677, states[40]= 0.000075
Saving checkpoint... 
Iteration: 1329559030, states[0] = 15.936163, states[40]= 0.008933
Saving checkpoint... 
Iteration: 1339131861, states[0] = -70.904366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1348751359, states[0] = -5.461890, states[40]= 0.004628
Saving checkpoint... 
Iteration: 1358295248, states[0] = -68.585130, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1368034534, states[0] = 28.286759, states[40]= 0.122466
Saving checkpoint... 
Iteration: 1377496978, states[0] = -87.716954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387015029, states[0] = -87.787317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396526399, states[0] = -87.823427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406122126, states[0] = -65.815170, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1415707947, states[0] = 20.209935, states[40]= 0.016152
Saving checkpoint... 
Iteration: 1425192159, states[0] = 41.440274, states[40]= 0.050324
Saving checkpoint... 
Iteration: 1434704570, states[0] = 20.784058, states[40]= 0.019733
Saving checkpoint... 
Iteration: 1444010101, states[0] = -87.789618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453298101, states[0] = -85.633725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462823646, states[0] = -87.724827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472611564, states[0] = -59.706798, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1482288687, states[0] = -78.509212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492148106, states[0] = -87.696804, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.700479
 - CaMKt in component CaMK (millimolar): 0.042710
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 6.988941
 - nass in component intracellular_ions (millimolar): 6.989090
 - ki in component intracellular_ions (millimolar): 144.930937
 - kss in component intracellular_ions (millimolar): 144.930904
 - cansr in component intracellular_ions (millimolar): 1.622288
 - cajsr in component intracellular_ions (millimolar): 1.188702
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007476
 - hf in component INa (dimensionless): 0.691938
 - hs in component INa (dimensionless): 0.691695
 - j in component INa (dimensionless): 0.680468
 - hsp in component INa (dimensionless): 0.446689
 - jp in component INa (dimensionless): 0.652924
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.289594
 - hLp in component INaL (dimensionless): 0.134131
 - a in component Ito (dimensionless): 0.001013
 - iF in component Ito (dimensionless): 0.999539
 - iS in component Ito (dimensionless): 0.173880
 - ap in component Ito (dimensionless): 0.000516
 - iFp in component Ito (dimensionless): 0.999539
 - iSp in component Ito (dimensionless): 0.210008
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.801592
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966131
 - jca in component ICaL (dimensionless): 0.947035
 - ffp in component ICaL (dimensionless): 0.999851
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009504
 - xrf in component IKr (dimensionless): 0.030031
 - xrs in component IKr (dimensionless): 0.789801
 - xs1 in component IKs (dimensionless): 0.461674
 - xs2 in component IKs (dimensionless): 0.001262
 - xk1 in component IK1 (dimensionless): 0.996812
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:04:28 (884): called boinc_finish(0)

</stderr_txt>
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