𝕏

Task 55462694

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_2000-conf_2_2
Workunit 26140144
Created 1 Jul 2024, 6:05:21 UTC
Sent 1 Jul 2024, 6:05:24 UTC
Report deadline 4 Jul 2024, 6:05:24 UTC
Received 3 Jul 2024, 9:56:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 2 hours 50 min 18 sec
CPU time 2 hours 17 min 42 sec
Validate state Valid
Credit 43.08
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_2000-conf_2.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_2000-conf_2_2_r791432826_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Drouin_MID_2000-conf_2_2_r791432826_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 111.166892
     * GNaL_b in INaL: 0.005760
     * Gto_b in Ito: 0.079305
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033728
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.154034
     * Gncx_b in INaCa_i: 0.000977
     * Pnak_b in INaK: 71.105132
     * GKb_b in IKb: 0.003693
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022246
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8742950, states[0] = -94.228327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16903556, states[0] = -94.207952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 25045490, states[0] = 33.783887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34225574, states[0] = -45.212697, states[40]= 0.001456
Saving checkpoint... 
Iteration: 41767432, states[0] = -94.241859, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50204247, states[0] = -35.620965, states[40]= 0.004351
Saving checkpoint... 
Iteration: 57604464, states[0] = -94.251212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 65378807, states[0] = -94.057404, states[40]= 0.000001
Saving checkpoint... 
Iteration: 71935950, states[0] = -94.270644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 81134291, states[0] = -1.127731, states[40]= 0.000684
Saving checkpoint... 
Iteration: 89639091, states[0] = -94.283850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 98560573, states[0] = -94.270919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 106167769, states[0] = -21.770912, states[40]= 0.003876
Saving checkpoint... 
Iteration: 114103219, states[0] = 11.892268, states[40]= 0.000067
Saving checkpoint... 
Iteration: 121746994, states[0] = -94.300851, states[40]= 0.000001
Saving checkpoint... 
Iteration: 129525591, states[0] = -94.265435, states[40]= 0.000001
Saving checkpoint... 
Iteration: 138586143, states[0] = -94.288317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 146524719, states[0] = -94.267199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 153563206, states[0] = -94.283223, states[40]= 0.000001
Saving checkpoint... 
Iteration: 161488640, states[0] = -94.246730, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169020865, states[0] = 33.958055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176918906, states[0] = -94.299431, states[40]= 0.000001
Saving checkpoint... 
Iteration: 184922505, states[0] = -94.299326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192797775, states[0] = -94.305167, states[40]= 0.000001
Saving checkpoint... 
Iteration: 200959128, states[0] = -94.297144, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208263515, states[0] = -93.544662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216249456, states[0] = -90.662966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225628005, states[0] = -94.298580, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234196732, states[0] = -38.488765, states[40]= 0.003256
Saving checkpoint... 
Iteration: 242155487, states[0] = -15.897790, states[40]= 0.001337
Saving checkpoint... 
Iteration: 250556124, states[0] = -94.281110, states[40]= 0.000001
Saving checkpoint... 
Iteration: 257915375, states[0] = -94.298634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 265170399, states[0] = -23.949745, states[40]= 0.005160
Saving checkpoint... 
Iteration: 273391946, states[0] = -94.126513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 281810930, states[0] = -94.302950, states[40]= 0.000001
Saving checkpoint... 
Iteration: 290974626, states[0] = -94.294131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298907138, states[0] = -94.297912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 305345532, states[0] = -94.006505, states[40]= 0.000001
Saving checkpoint... 
Iteration: 313141242, states[0] = -6.611989, states[40]= 0.000970
Saving checkpoint... 
Iteration: 322385615, states[0] = -94.112116, states[40]= 0.000001
Saving checkpoint... 
Iteration: 331022452, states[0] = 34.116964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338394516, states[0] = -94.129516, states[40]= 0.000001
Saving checkpoint... 
Iteration: 346733949, states[0] = -94.302108, states[40]= 0.000001
Saving checkpoint... 
Iteration: 354765239, states[0] = -94.301770, states[40]= 0.000001
Saving checkpoint... 
Iteration: 363077970, states[0] = 21.794970, states[40]= 0.000005
Saving checkpoint... 
Iteration: 371125827, states[0] = 1.663670, states[40]= 0.000471
Saving checkpoint... 
Iteration: 377763750, states[0] = -94.301047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 385285297, states[0] = -93.722467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392971756, states[0] = -94.291079, states[40]= 0.000001
Saving checkpoint... 
Iteration: 400690200, states[0] = -94.299162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 408999098, states[0] = -94.288856, states[40]= 0.000001
Saving checkpoint... 
Iteration: 416830306, states[0] = -94.297958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 424298162, states[0] = -93.797834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432045593, states[0] = 32.174965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439878166, states[0] = -94.294983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 448020738, states[0] = 33.928782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456646294, states[0] = -94.293914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 464708949, states[0] = -94.297839, states[40]= 0.000001
Saving checkpoint... 
Iteration: 472707816, states[0] = -94.297544, states[40]= 0.000001
Saving checkpoint... 
Iteration: 482935341, states[0] = -94.290383, states[40]= 0.000001
Saving checkpoint... 
Iteration: 490894633, states[0] = -94.292458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 497832514, states[0] = -94.295251, states[40]= 0.000001
Saving checkpoint... 
Iteration: 506403338, states[0] = -94.140183, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514281880, states[0] = -93.695987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521961146, states[0] = -94.287565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 529798771, states[0] = -94.295411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 537508170, states[0] = -94.250174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 545180491, states[0] = -28.862548, states[40]= 0.006262
Saving checkpoint... 
Iteration: 552899767, states[0] = -94.290170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 560458427, states[0] = -94.211392, states[40]= 0.000001
Saving checkpoint... 
Iteration: 568313072, states[0] = -93.869507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575905711, states[0] = -94.289096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 583606219, states[0] = -94.283821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 591641491, states[0] = -94.288999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 600065534, states[0] = 26.352391, states[40]= 0.000001
Saving checkpoint... 
Iteration: 607862890, states[0] = -94.290329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 615472821, states[0] = -94.222700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 623458412, states[0] = -94.209326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 631835833, states[0] = -94.290789, states[40]= 0.000001
Saving checkpoint... 
Iteration: 640543989, states[0] = -94.264211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 648740105, states[0] = -94.292400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 656253500, states[0] = -92.684047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 664347033, states[0] = -93.999604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 671219029, states[0] = -55.375544, states[40]= 0.000404
Saving checkpoint... 
Iteration: 678768418, states[0] = -94.291274, states[40]= 0.000001
Saving checkpoint... 
Iteration: 686050874, states[0] = 30.894800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693260850, states[0] = -93.468529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700709630, states[0] = -94.290255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 707336563, states[0] = -93.962411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 714705251, states[0] = -94.289664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 722415771, states[0] = -94.153513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 729314338, states[0] = -93.870145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736836805, states[0] = -94.287374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744294908, states[0] = -93.768780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752665575, states[0] = -94.286214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 759355487, states[0] = -94.022554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 766257671, states[0] = -93.307759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773571858, states[0] = -94.269460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 780395048, states[0] = -94.116129, states[40]= 0.000001
Saving checkpoint... 
Iteration: 788233164, states[0] = -68.273995, states[40]= 0.000059
Saving checkpoint... 
Iteration: 795408638, states[0] = -94.139781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 803102180, states[0] = 12.037270, states[40]= 0.000066
Saving checkpoint... 
Iteration: 810884630, states[0] = -94.282678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819580702, states[0] = -94.270422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 827480550, states[0] = -94.222107, states[40]= 0.000001
Saving checkpoint... 
Iteration: 834412893, states[0] = -94.145380, states[40]= 0.000001
Saving checkpoint... 
Iteration: 843658464, states[0] = -94.282658, states[40]= 0.000001
Saving checkpoint... 
Iteration: 852108609, states[0] = 9.323401, states[40]= 0.000119
Saving checkpoint... 
Iteration: 859298786, states[0] = -93.786814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865951627, states[0] = -94.277050, states[40]= 0.000001
Saving checkpoint... 
Iteration: 876292244, states[0] = -93.748803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886825212, states[0] = -94.282997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897747983, states[0] = -94.284382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 908761117, states[0] = -94.283950, states[40]= 0.000001
Saving checkpoint... 
Iteration: 919496523, states[0] = -94.230581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930203936, states[0] = -43.598056, states[40]= 0.001871
Saving checkpoint... 
Iteration: 941043300, states[0] = 32.661199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951571199, states[0] = -94.263514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 962728084, states[0] = -94.282176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 973588740, states[0] = -94.267464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 983956642, states[0] = -94.272936, states[40]= 0.000001
Saving checkpoint... 
Iteration: 994636096, states[0] = -94.275325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1005064300, states[0] = 26.782058, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1015194268, states[0] = -36.856958, states[40]= 0.003797
Saving checkpoint... 
Iteration: 1026087156, states[0] = 18.204471, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1036749262, states[0] = -94.279913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1047741502, states[0] = -94.279555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1058631613, states[0] = -94.272677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1069955976, states[0] = -94.270214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1080857165, states[0] = -94.275364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1091710378, states[0] = -94.277661, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1101875975, states[0] = -94.273752, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1112624133, states[0] = -94.269842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1123489530, states[0] = -94.219207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1134326130, states[0] = -93.908174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145124531, states[0] = 2.293182, states[40]= 0.000428
Saving checkpoint... 
Iteration: 1155752548, states[0] = -94.276053, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166983206, states[0] = -94.265397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1178134068, states[0] = -2.449182, states[40]= 0.000759
Saving checkpoint... 
Iteration: 1188462295, states[0] = -94.194747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1198978267, states[0] = -94.264674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1209167185, states[0] = -22.393176, states[40]= 0.004137
Saving checkpoint... 
Iteration: 1219415023, states[0] = -94.136185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1230359818, states[0] = -94.019519, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1241167224, states[0] = -22.410772, states[40]= 0.004148
Saving checkpoint... 
Iteration: 1251544617, states[0] = -94.244720, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1261874831, states[0] = -94.268640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273007423, states[0] = 28.205712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284112949, states[0] = 7.469109, states[40]= 0.000173
Saving checkpoint... 
Iteration: 1295105265, states[0] = 10.749292, states[40]= 0.000088
Saving checkpoint... 
Iteration: 1306034167, states[0] = 34.023723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316367121, states[0] = -94.036377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1326987588, states[0] = -94.259973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1337855789, states[0] = -94.267149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1348113657, states[0] = 7.163738, states[40]= 0.000183
Saving checkpoint... 
Iteration: 1358542868, states[0] = -94.240582, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1369175393, states[0] = -26.286661, states[40]= 0.006116
Saving checkpoint... 
Iteration: 1379909120, states[0] = -94.262990, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1391136025, states[0] = -3.511538, states[40]= 0.000825
Saving checkpoint... 
Iteration: 1401374900, states[0] = -94.052900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1411751044, states[0] = -94.267809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422390463, states[0] = -94.086233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1432886551, states[0] = -94.262521, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1443697948, states[0] = -94.265880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1454528413, states[0] = -94.231161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1465266642, states[0] = -93.546220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476077842, states[0] = 21.858802, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1486962840, states[0] = -94.256341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1497840533, states[0] = -94.262670, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.129545
 - CaMKt in component CaMK (millimolar): 0.009357
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 8.108212
 - nass in component intracellular_ions (millimolar): 8.108387
 - ki in component intracellular_ions (millimolar): 143.467035
 - kss in component intracellular_ions (millimolar): 143.467011
 - cansr in component intracellular_ions (millimolar): 2.086529
 - cajsr in component intracellular_ions (millimolar): 2.088914
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003912
 - hf in component INa (dimensionless): 0.865940
 - hs in component INa (dimensionless): 0.865943
 - j in component INa (dimensionless): 0.865957
 - hsp in component INa (dimensionless): 0.699910
 - jp in component INa (dimensionless): 0.865965
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708085
 - hLp in component INaL (dimensionless): 0.490099
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.872221
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.914125
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.959862
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005141
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.124449
 - xs1 in component IKs (dimensionless): 0.167961
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997533
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
11:56:18 (12376): called boinc_finish(0)

</stderr_txt>
]]>