𝕏

Task 55462693

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-BASE_MID-conf_404_2
Workunit 26239728
Created 1 Jul 2024, 6:04:01 UTC
Sent 1 Jul 2024, 6:04:04 UTC
Report deadline 4 Jul 2024, 6:04:04 UTC
Received 3 Jul 2024, 9:37:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 2 hours 47 min 4 sec
CPU time 2 hours 17 min 7 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.22 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-BASE_MID-conf_404.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-BASE_MID-conf_404_2_r1655739432_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-BASE_MID-conf_404_2_r1655739432_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 101.966277
     * GNaL_b in INaL: 0.005297
     * Gto_b in Ito: 0.072711
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030418
     * GKs_b in IKs: 0.002126
     * GK1_b in IK1: 0.169613
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 72.704348
     * GKb_b in IKb: 0.003732
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036062
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7471498, states[0] = -86.807163, states[40]= 0.000001
Saving checkpoint... 
Iteration: 16579476, states[0] = 18.298829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 24829816, states[0] = -86.692076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 34497558, states[0] = -86.867335, states[40]= 0.000002
Saving checkpoint... 
Iteration: 42828035, states[0] = -86.719106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 51345878, states[0] = -86.765210, states[40]= 0.000001
Saving checkpoint... 
Iteration: 59283411, states[0] = -86.613243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67362353, states[0] = -86.807376, states[40]= 0.000002
Saving checkpoint... 
Iteration: 75622339, states[0] = -5.817713, states[40]= 0.000110
Saving checkpoint... 
Iteration: 83861785, states[0] = -86.817095, states[40]= 0.000002
Saving checkpoint... 
Iteration: 92201810, states[0] = -84.284293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99909748, states[0] = -86.876656, states[40]= 0.000002
Saving checkpoint... 
Iteration: 107961740, states[0] = -86.911908, states[40]= 0.000002
Saving checkpoint... 
Iteration: 116363955, states[0] = -86.830083, states[40]= 0.000002
Saving checkpoint... 
Iteration: 125493524, states[0] = -86.927290, states[40]= 0.000002
Saving checkpoint... 
Iteration: 133372231, states[0] = -86.843181, states[40]= 0.000002
Saving checkpoint... 
Iteration: 141359093, states[0] = -86.825597, states[40]= 0.000002
Saving checkpoint... 
Iteration: 149243075, states[0] = -86.455195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158215584, states[0] = -86.256665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165632156, states[0] = -15.191760, states[40]= 0.000130
Saving checkpoint... 
Iteration: 173627773, states[0] = -11.575730, states[40]= 0.000126
Saving checkpoint... 
Iteration: 180777563, states[0] = -86.622965, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188565569, states[0] = 21.505442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196560370, states[0] = 23.521365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204532514, states[0] = 31.689497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213472365, states[0] = -86.920093, states[40]= 0.000002
Saving checkpoint... 
Iteration: 220942369, states[0] = -86.904914, states[40]= 0.000002
Saving checkpoint... 
Iteration: 229006354, states[0] = 24.647260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238198534, states[0] = -83.222238, states[40]= 0.000001
Saving checkpoint... 
Iteration: 246529952, states[0] = 32.080522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253954183, states[0] = -86.909961, states[40]= 0.000002
Saving checkpoint... 
Iteration: 261391194, states[0] = -86.862898, states[40]= 0.000002
Saving checkpoint... 
Iteration: 269212452, states[0] = -86.211469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276638357, states[0] = -20.338894, states[40]= 0.000187
Saving checkpoint... 
Iteration: 285738233, states[0] = -86.421573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293636159, states[0] = -18.592425, states[40]= 0.000156
Saving checkpoint... 
Iteration: 301589881, states[0] = 10.906535, states[40]= 0.000010
Saving checkpoint... 
Iteration: 310134146, states[0] = -16.954063, states[40]= 0.000139
Saving checkpoint... 
Iteration: 318738515, states[0] = -86.421701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327186967, states[0] = -66.328646, states[40]= 0.000009
Saving checkpoint... 
Iteration: 334478998, states[0] = -86.917225, states[40]= 0.000002
Saving checkpoint... 
Iteration: 342965201, states[0] = -86.911028, states[40]= 0.000002
Saving checkpoint... 
Iteration: 350062298, states[0] = 22.777823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358191639, states[0] = -73.658057, states[40]= 0.000003
Saving checkpoint... 
Iteration: 368157498, states[0] = -35.448230, states[40]= 0.000311
Saving checkpoint... 
Iteration: 376729520, states[0] = -86.359630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384617382, states[0] = -3.801625, states[40]= 0.000102
Saving checkpoint... 
Iteration: 392927056, states[0] = -86.887048, states[40]= 0.000002
Saving checkpoint... 
Iteration: 401040781, states[0] = 29.891909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408541295, states[0] = 29.758220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415916283, states[0] = -86.877997, states[40]= 0.000002
Saving checkpoint... 
Iteration: 423602822, states[0] = 4.588005, states[40]= 0.000035
Saving checkpoint... 
Iteration: 431955093, states[0] = -86.901850, states[40]= 0.000002
Saving checkpoint... 
Iteration: 441640689, states[0] = -22.137599, states[40]= 0.000232
Saving checkpoint... 
Iteration: 451182350, states[0] = -60.192834, states[40]= 0.000021
Saving checkpoint... 
Iteration: 459216453, states[0] = -86.253097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467477483, states[0] = -86.910153, states[40]= 0.000002
Saving checkpoint... 
Iteration: 476884457, states[0] = -86.845205, states[40]= 0.000002
Saving checkpoint... 
Iteration: 486015523, states[0] = 31.685653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494758287, states[0] = -86.523280, states[40]= 0.000001
Saving checkpoint... 
Iteration: 502600645, states[0] = 5.698260, states[40]= 0.000029
Saving checkpoint... 
Iteration: 511019515, states[0] = 32.443437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520372579, states[0] = -86.828933, states[40]= 0.000002
Saving checkpoint... 
Iteration: 529976331, states[0] = -86.906659, states[40]= 0.000002
Saving checkpoint... 
Iteration: 537457828, states[0] = -86.898068, states[40]= 0.000002
Saving checkpoint... 
Iteration: 546037641, states[0] = 30.660292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554874937, states[0] = -86.830198, states[40]= 0.000002
Saving checkpoint... 
Iteration: 562649698, states[0] = -29.022822, states[40]= 0.000380
Saving checkpoint... 
Iteration: 569967312, states[0] = -86.900904, states[40]= 0.000002
Saving checkpoint... 
Iteration: 577968189, states[0] = -86.900901, states[40]= 0.000002
Saving checkpoint... 
Iteration: 586619102, states[0] = -4.965763, states[40]= 0.000110
Saving checkpoint... 
Iteration: 595502967, states[0] = 20.285760, states[40]= 1.206070
Saving checkpoint... 
Iteration: 604288721, states[0] = -86.643840, states[40]= 0.000001
Saving checkpoint... 
Iteration: 612960625, states[0] = -86.895745, states[40]= 0.000002
Saving checkpoint... 
Iteration: 621724367, states[0] = -86.310448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629907360, states[0] = -86.860224, states[40]= 0.000002
Saving checkpoint... 
Iteration: 637103711, states[0] = 4.136437, states[40]= 0.000038
Saving checkpoint... 
Iteration: 643766030, states[0] = -86.552471, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651689771, states[0] = -70.530568, states[40]= 0.000005
Saving checkpoint... 
Iteration: 660944802, states[0] = -86.885134, states[40]= 0.000002
Saving checkpoint... 
Iteration: 668271386, states[0] = -86.574638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676986152, states[0] = -86.903193, states[40]= 0.000002
Saving checkpoint... 
Iteration: 685345217, states[0] = -86.779934, states[40]= 0.000002
Saving checkpoint... 
Iteration: 694175054, states[0] = -52.004403, states[40]= 0.000059
Saving checkpoint... 
Iteration: 702255492, states[0] = -86.498827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 711587491, states[0] = 12.027231, states[40]= 0.000008
Saving checkpoint... 
Iteration: 719832291, states[0] = -86.753929, states[40]= 0.000002
Saving checkpoint... 
Iteration: 728993330, states[0] = -86.903128, states[40]= 0.000002
Saving checkpoint... 
Iteration: 737520424, states[0] = 32.527472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745713289, states[0] = -86.200057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753379198, states[0] = -86.825630, states[40]= 0.000002
Saving checkpoint... 
Iteration: 761239107, states[0] = -86.403127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769535980, states[0] = 31.030711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777447117, states[0] = -86.880762, states[40]= 0.000002
Saving checkpoint... 
Iteration: 786608810, states[0] = 1.411320, states[40]= 0.000058
Saving checkpoint... 
Iteration: 795075582, states[0] = 17.350353, states[40]= 0.000002
Saving checkpoint... 
Iteration: 802979583, states[0] = -86.894630, states[40]= 0.000002
Saving checkpoint... 
Iteration: 810859101, states[0] = -86.796142, states[40]= 0.000002
Saving checkpoint... 
Iteration: 819484965, states[0] = -86.895833, states[40]= 0.000002
Saving checkpoint... 
Iteration: 827468533, states[0] = -86.888896, states[40]= 0.000002
Saving checkpoint... 
Iteration: 835009743, states[0] = 28.699235, states[40]= -0.000000
Saving checkpoint... 
Iteration: 842050301, states[0] = 27.092221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850309325, states[0] = -86.693982, states[40]= 0.000001
Saving checkpoint... 
Iteration: 857900618, states[0] = -86.843030, states[40]= 0.000002
Saving checkpoint... 
Iteration: 865506325, states[0] = 24.598379, states[40]= -0.000000
Saving checkpoint... 
Iteration: 873401589, states[0] = -86.843186, states[40]= 0.000002
Saving checkpoint... 
Iteration: 881585792, states[0] = 12.812290, states[40]= 0.000006
Saving checkpoint... 
Iteration: 889537852, states[0] = 30.618811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898693018, states[0] = -75.802488, states[40]= 0.000002
Saving checkpoint... 
Iteration: 907475932, states[0] = -86.888100, states[40]= 0.000002
Saving checkpoint... 
Iteration: 915008876, states[0] = 27.932201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922701823, states[0] = -85.042570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931573305, states[0] = 18.325555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 941113706, states[0] = -1.425058, states[40]= 0.000083
Saving checkpoint... 
Iteration: 951317624, states[0] = -86.710052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 961379778, states[0] = -86.816148, states[40]= 0.000002
Saving checkpoint... 
Iteration: 971812024, states[0] = -86.695075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982127297, states[0] = -11.218475, states[40]= 0.000125
Saving checkpoint... 
Iteration: 993047876, states[0] = 27.871333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003344516, states[0] = -86.763094, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1014125452, states[0] = -9.718833, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1024117405, states[0] = -3.780713, states[40]= 0.000101
Saving checkpoint... 
Iteration: 1035177102, states[0] = -54.129222, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1045871819, states[0] = -86.802222, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1056415945, states[0] = -86.846468, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1067383215, states[0] = -86.814924, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1078522566, states[0] = 32.618221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089386418, states[0] = -86.817401, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1100204462, states[0] = -85.682472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111179013, states[0] = -56.211228, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1121630316, states[0] = -13.710318, states[40]= 0.000126
Saving checkpoint... 
Iteration: 1133017452, states[0] = 32.157268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144239112, states[0] = -86.383918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155228711, states[0] = -86.314719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166030024, states[0] = 32.088214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176965549, states[0] = -86.870547, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1187214373, states[0] = -86.192179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197522735, states[0] = 32.621686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208496886, states[0] = -86.880929, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1219339629, states[0] = -86.743644, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1230251499, states[0] = -86.451430, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1241519237, states[0] = 32.427653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252876792, states[0] = -86.798314, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1263802038, states[0] = -86.653268, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1274786083, states[0] = -86.601432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1285299185, states[0] = -86.643743, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1295932608, states[0] = -86.846726, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1307013319, states[0] = 30.899154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317838445, states[0] = -86.736593, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1328699581, states[0] = -83.851725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339552024, states[0] = 26.528984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351079922, states[0] = 15.467523, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1361706445, states[0] = -85.903556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372081872, states[0] = 14.599403, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1382597411, states[0] = 7.332085, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1392773613, states[0] = -86.547900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1403782351, states[0] = -86.581535, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1414602698, states[0] = 4.685818, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1425612704, states[0] = -0.797363, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1435851564, states[0] = -86.753797, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1446787997, states[0] = -86.599613, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1458100590, states[0] = 5.757043, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1469044532, states[0] = 28.886539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480183420, states[0] = -61.349420, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1490993424, states[0] = -86.866090, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.743611
 - CaMKt in component CaMK (millimolar): 0.024237
 - cass in component intracellular_ions (millimolar): 0.000091
 - nai in component intracellular_ions (millimolar): 7.942760
 - nass in component intracellular_ions (millimolar): 7.942904
 - ki in component intracellular_ions (millimolar): 143.520643
 - kss in component intracellular_ions (millimolar): 143.520608
 - cansr in component intracellular_ions (millimolar): 1.979848
 - cajsr in component intracellular_ions (millimolar): 1.909484
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.008231
 - hf in component INa (dimensionless): 0.657448
 - hs in component INa (dimensionless): 0.657419
 - j in component INa (dimensionless): 0.657250
 - hsp in component INa (dimensionless): 0.409215
 - jp in component INa (dimensionless): 0.657130
 - mL in component INaL (dimensionless): 0.000234
 - hL in component INaL (dimensionless): 0.453441
 - hLp in component INaL (dimensionless): 0.219734
 - a in component Ito (dimensionless): 0.001081
 - iF in component Ito (dimensionless): 0.999456
 - iS in component Ito (dimensionless): 0.530380
 - ap in component Ito (dimensionless): 0.000551
 - iFp in component Ito (dimensionless): 0.999456
 - iSp in component Ito (dimensionless): 0.573421
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.874536
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999586
 - jca in component ICaL (dimensionless): 0.999936
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003576
 - xrf in component IKr (dimensionless): 0.000011
 - xrs in component IKr (dimensionless): 0.513912
 - xs1 in component IKs (dimensionless): 0.337185
 - xs2 in component IKs (dimensionless): 0.000219
 - xk1 in component IK1 (dimensionless): 0.997045
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
11:37:38 (6068): called boinc_finish(0)

</stderr_txt>
]]>


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