𝕏

Task 55462564

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_6000-conf_507_3
Workunit 25881983
Created 1 Jul 2024, 5:48:12 UTC
Sent 1 Jul 2024, 5:48:14 UTC
Report deadline 4 Jul 2024, 5:48:14 UTC
Received 1 Jul 2024, 10:08:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232855
Run time 2 hours 35 min 26 sec
CPU time 37 min 5 sec
Validate state Valid
Credit 43.70
Device peak FLOPS 6.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.50 MB
Peak swap size 5.31 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_6000-conf_507.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_6000-conf_507_3_r1155017459_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_MID_6000-conf_507_3_r1155017459_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 119.117371
     * GNaL_b in INaL: 0.007704
     * Gto_b in Ito: 0.090030
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033636
     * GKs_b in IKs: 0.001816
     * GK1_b in IK1: 0.143123
     * Gncx_b in INaCa_i: 0.000946
     * Pnak_b in INaK: 62.947911
     * GKb_b in IKb: 0.003873
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041350
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15701232, states[0] = -93.788259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24195126, states[0] = -17.087023, states[40]= 0.002893
Saving checkpoint... 
Iteration: 32507804, states[0] = -93.803181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 40812548, states[0] = -93.828809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 49178900, states[0] = -93.861286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 57795796, states[0] = -93.882349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66178964, states[0] = -15.253379, states[40]= 0.001199
Saving checkpoint... 
Iteration: 74911040, states[0] = -93.859522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 82813829, states[0] = -93.876413, states[40]= 0.000001
Saving checkpoint... 
Iteration: 91435893, states[0] = -93.891733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 99610845, states[0] = -93.891737, states[40]= 0.000001
Saving checkpoint... 
Iteration: 108225811, states[0] = -34.865179, states[40]= 0.004097
Saving checkpoint... 
Iteration: 116639204, states[0] = -93.885005, states[40]= 0.000001
Saving checkpoint... 
Iteration: 125142434, states[0] = -93.891751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 133403096, states[0] = -93.909271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 141758200, states[0] = -93.928222, states[40]= 0.000001
Saving checkpoint... 
Iteration: 150634292, states[0] = -93.913936, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158790788, states[0] = -93.893710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 167175039, states[0] = -93.898890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 175395364, states[0] = -93.915525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 183934715, states[0] = -93.933101, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192459072, states[0] = -93.806930, states[40]= 0.000001
Saving checkpoint... 
Iteration: 200934789, states[0] = -93.896490, states[40]= 0.000001
Saving checkpoint... 
Iteration: 209146204, states[0] = -93.901734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 217851119, states[0] = -93.906266, states[40]= 0.000001
Saving checkpoint... 
Iteration: 226279191, states[0] = -93.921674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234485295, states[0] = -93.838794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 242794829, states[0] = -93.897821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 251755902, states[0] = -93.898029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 260415802, states[0] = -93.899933, states[40]= 0.000001
Saving checkpoint... 
Iteration: 268716936, states[0] = -93.909413, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276845289, states[0] = -93.936554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285166087, states[0] = -11.986725, states[40]= 0.000705
Saving checkpoint... 
Iteration: 293148302, states[0] = -93.902439, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301818379, states[0] = -93.907324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 310081388, states[0] = -93.929599, states[40]= 0.000001
Saving checkpoint... 
Iteration: 319069900, states[0] = -93.930010, states[40]= 0.000001
Saving checkpoint... 
Iteration: 327994997, states[0] = -93.932805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 336436119, states[0] = -93.774850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 344473410, states[0] = -93.899272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 353013060, states[0] = -93.903867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 361456576, states[0] = -93.915701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 369991720, states[0] = -93.932653, states[40]= 0.000001
Saving checkpoint... 
Iteration: 378108270, states[0] = 12.942976, states[40]= 0.000024
Saving checkpoint... 
Iteration: 386384563, states[0] = -93.899632, states[40]= 0.000001
Saving checkpoint... 
Iteration: 393987210, states[0] = -93.932641, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401815125, states[0] = -93.897212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 410305018, states[0] = -93.900127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 418560360, states[0] = -93.912358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 426773161, states[0] = -93.934696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 435641370, states[0] = -93.920030, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444179670, states[0] = -18.915753, states[40]= 0.002048
Saving checkpoint... 
Iteration: 452870885, states[0] = -93.896663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 461580878, states[0] = -93.897774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470538099, states[0] = -93.897950, states[40]= 0.000001
Saving checkpoint... 
Iteration: 479209404, states[0] = -93.900538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 487986632, states[0] = -93.903258, states[40]= 0.000001
Saving checkpoint... 
Iteration: 496297807, states[0] = -93.919946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 504232806, states[0] = -42.370357, states[40]= 0.001679
Saving checkpoint... 
Iteration: 513120211, states[0] = 8.493148, states[40]= 0.000067
Saving checkpoint... 
Iteration: 521598674, states[0] = -93.897222, states[40]= 0.000001
Saving checkpoint... 
Iteration: 529764874, states[0] = -93.906777, states[40]= 0.000001
Saving checkpoint... 
Iteration: 537999672, states[0] = -93.931115, states[40]= 0.000001
Saving checkpoint... 
Iteration: 546346224, states[0] = -93.531913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554506216, states[0] = -93.897506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 563296150, states[0] = -93.899049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571121507, states[0] = -93.926135, states[40]= 0.000001
Saving checkpoint... 
Iteration: 579591304, states[0] = -93.904584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587906623, states[0] = -93.895540, states[40]= 0.000001
Saving checkpoint... 
Iteration: 596057847, states[0] = -93.901440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 604007781, states[0] = -93.930318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 612594597, states[0] = -93.905514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 620544968, states[0] = -93.896766, states[40]= 0.000001
Saving checkpoint... 
Iteration: 629504258, states[0] = -93.896945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637187246, states[0] = -93.923028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 645936165, states[0] = -93.932376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 654418157, states[0] = -93.740156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662888836, states[0] = -93.895011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 671096046, states[0] = -93.900374, states[40]= 0.000001
Saving checkpoint... 
Iteration: 679262693, states[0] = -93.919831, states[40]= 0.000001
Saving checkpoint... 
Iteration: 687692685, states[0] = -93.926713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 696256973, states[0] = -60.364174, states[40]= 0.000124
Saving checkpoint... 
Iteration: 704449103, states[0] = -93.896740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 712779878, states[0] = -93.905080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 720893845, states[0] = -93.932843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 729318269, states[0] = -93.398917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737603298, states[0] = -93.895547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 746251220, states[0] = -93.898075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 755430576, states[0] = -93.896483, states[40]= 0.000001
Saving checkpoint... 
Iteration: 763937836, states[0] = -93.901895, states[40]= 0.000001
Saving checkpoint... 
Iteration: 772475699, states[0] = -93.912029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 781192163, states[0] = -93.921738, states[40]= 0.000001
Saving checkpoint... 
Iteration: 789343434, states[0] = -93.518379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797584428, states[0] = -93.895188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806208722, states[0] = -93.898047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 813977655, states[0] = -93.929784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 822180068, states[0] = -19.074033, states[40]= 0.002136
Saving checkpoint... 
Iteration: 830664512, states[0] = -93.894533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 839360534, states[0] = -93.896380, states[40]= 0.000001
Saving checkpoint... 
Iteration: 847728666, states[0] = -93.905095, states[40]= 0.000001
Saving checkpoint... 
Iteration: 855951458, states[0] = -93.930318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864073362, states[0] = 25.504487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 872580283, states[0] = -93.894637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 880990419, states[0] = -93.900199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 889430888, states[0] = -93.912489, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897284618, states[0] = -90.686701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 905878847, states[0] = -93.893179, states[40]= 0.000001
Saving checkpoint... 
Iteration: 914472491, states[0] = -93.894973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 923170421, states[0] = -93.897568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931761001, states[0] = -93.903784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940161248, states[0] = -93.921739, states[40]= 0.000001
Saving checkpoint... 
Iteration: 948282080, states[0] = -88.541012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 957130655, states[0] = 4.558747, states[40]= 0.000150
Saving checkpoint... 
Iteration: 965607722, states[0] = -93.893779, states[40]= 0.000001
Saving checkpoint... 
Iteration: 974015640, states[0] = -93.899125, states[40]= 0.000001
Saving checkpoint... 
Iteration: 982553864, states[0] = -93.908231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 990888589, states[0] = -93.930884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 999162606, states[0] = -10.021440, states[40]= 0.000655
Saving checkpoint... 
Iteration: 1007890656, states[0] = -93.892366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1016243360, states[0] = -93.896086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024742318, states[0] = -93.903455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033312386, states[0] = -93.915327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1041715472, states[0] = -93.926451, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1050089762, states[0] = 19.770925, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1058208615, states[0] = -93.896120, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1067228133, states[0] = -93.895850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1075558564, states[0] = -93.907396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1084110882, states[0] = -93.922645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1092787657, states[0] = -93.930073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1101426931, states[0] = -93.753216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1109530276, states[0] = -93.893112, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1117105192, states[0] = -93.922620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1125680844, states[0] = -93.921806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1134229972, states[0] = -40.419983, states[40]= 0.002128
Saving checkpoint... 
Iteration: 1142789005, states[0] = -93.891644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1151430830, states[0] = -93.893450, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1159990455, states[0] = -93.898065, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1168520191, states[0] = -93.907728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1176964519, states[0] = -93.927454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1185385091, states[0] = -93.658709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193948537, states[0] = -93.890801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1202233332, states[0] = -93.894764, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1210811809, states[0] = -93.900656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1219536881, states[0] = -93.906878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1228419682, states[0] = -93.910250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1237052785, states[0] = -93.923778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246037050, states[0] = -93.924318, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1254946621, states[0] = -93.927423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1263466514, states[0] = -93.810929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1271705375, states[0] = -93.890979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1279997246, states[0] = -93.897049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1288787760, states[0] = -93.900522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1296777100, states[0] = -93.928205, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1305446464, states[0] = -93.783609, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1314015877, states[0] = 31.406319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322760157, states[0] = -93.890370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1331639697, states[0] = -93.890817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1339997042, states[0] = -93.896592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1348824560, states[0] = -93.899362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1357378468, states[0] = -93.910592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1365921006, states[0] = -93.927297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1374627876, states[0] = -93.909689, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1383600202, states[0] = -93.901547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1391967888, states[0] = -93.889244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1400631948, states[0] = -93.890327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408818765, states[0] = -93.899012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1416921569, states[0] = -93.926895, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1425258790, states[0] = -61.794478, states[40]= 0.000099
Saving checkpoint... 
Iteration: 1433698412, states[0] = -93.889769, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1442291685, states[0] = -93.892366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450449450, states[0] = -93.907634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459177785, states[0] = -93.917125, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1468010218, states[0] = -93.923637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1476739821, states[0] = -93.925036, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1485871924, states[0] = -93.927379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1494631109, states[0] = -93.909578, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.764334
 - CaMKt in component CaMK (millimolar): 0.001447
 - cass in component intracellular_ions (millimolar): 0.000098
 - nai in component intracellular_ions (millimolar): 8.031790
 - nass in component intracellular_ions (millimolar): 8.031946
 - ki in component intracellular_ions (millimolar): 143.788022
 - kss in component intracellular_ions (millimolar): 143.788009
 - cansr in component intracellular_ions (millimolar): 1.825563
 - cajsr in component intracellular_ions (millimolar): 1.826926
 - cai in component intracellular_ions (millimolar): 0.000103
 - m in component INa (dimensionless): 0.004059
 - hf in component INa (dimensionless): 0.858819
 - hs in component INa (dimensionless): 0.858819
 - j in component INa (dimensionless): 0.858819
 - hsp in component INa (dimensionless): 0.687140
 - jp in component INa (dimensionless): 0.858820
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.698147
 - hLp in component INaL (dimensionless): 0.502628
 - a in component Ito (dimensionless): 0.000673
 - iF in component Ito (dimensionless): 0.999841
 - iS in component Ito (dimensionless): 0.999106
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999841
 - iSp in component Ito (dimensionless): 0.999662
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999288
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004794
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000703
 - xs1 in component IKs (dimensionless): 0.019463
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997620
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
03:06:07 (14808): called boinc_finish(0)

</stderr_txt>
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