𝕏

Task 55462563

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_ENDO_6000-conf_207_3
Workunit 25881854
Created 1 Jul 2024, 5:48:12 UTC
Sent 1 Jul 2024, 5:48:14 UTC
Report deadline 4 Jul 2024, 5:48:14 UTC
Received 1 Jul 2024, 10:08:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232855
Run time 2 hours 34 min 33 sec
CPU time 37 min
Validate state Valid
Credit 42.36
Device peak FLOPS 6.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.53 MB
Peak swap size 5.33 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_ENDO_6000-conf_207.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_ENDO_6000-conf_207_3_r855450067_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Drouin_ENDO_6000-conf_207_3_r855450067_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.748038
     * GNaL_b in INaL: 0.008736
     * Gto_b in Ito: 0.072482
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032925
     * GKs_b in IKs: 0.001779
     * GK1_b in IK1: 0.159750
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 63.144613
     * GKb_b in IKb: 0.003948
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051494
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15208293, states[0] = -83.009046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 23708499, states[0] = -94.009789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32437415, states[0] = -93.987476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41035873, states[0] = -93.980323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49493594, states[0] = -93.985376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58467279, states[0] = -93.983758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67115570, states[0] = -93.994381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75089048, states[0] = 11.361422, states[40]= 0.002567
Saving checkpoint... 
Iteration: 83398897, states[0] = -93.967367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92108346, states[0] = -93.970837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100217376, states[0] = -93.990988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108491658, states[0] = -93.959736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116906441, states[0] = -93.964150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125475593, states[0] = -93.967527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134074207, states[0] = -93.972118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142359972, states[0] = -93.987037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150424462, states[0] = -93.912485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158885855, states[0] = -93.964774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167144792, states[0] = -93.971467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175760828, states[0] = -93.977491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184378655, states[0] = -93.986714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192690839, states[0] = -94.003915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201317888, states[0] = -93.732093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209779014, states[0] = -93.965620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217984311, states[0] = -93.973773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226416048, states[0] = -93.985665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234878735, states[0] = -94.004218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243140149, states[0] = -19.683651, states[40]= 0.002195
Saving checkpoint... 
Iteration: 252332513, states[0] = -93.769442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260567548, states[0] = -93.967202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269153874, states[0] = -93.971425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277848646, states[0] = -93.975917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286711706, states[0] = -93.978473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295584678, states[0] = -93.981231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304348109, states[0] = -93.987604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313258501, states[0] = -93.990486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321696042, states[0] = -94.004097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330231759, states[0] = -93.084658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338266439, states[0] = -93.970003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346479933, states[0] = -93.983770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354672424, states[0] = -94.002669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363301786, states[0] = -93.684032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372422149, states[0] = -93.910263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380873080, states[0] = -93.964813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389220300, states[0] = -93.970451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397580442, states[0] = -93.981177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405774609, states[0] = -94.005654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414412699, states[0] = -93.900448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422977271, states[0] = -93.964115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431222506, states[0] = -93.970359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439466808, states[0] = -93.983975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448325065, states[0] = -93.988101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456539814, states[0] = -93.979819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464873320, states[0] = -93.964678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473847919, states[0] = -93.964826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482515685, states[0] = -93.967315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490552482, states[0] = -93.981700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498910037, states[0] = -94.002907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507811398, states[0] = -94.005250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516425844, states[0] = -93.913613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525186785, states[0] = -53.848735, states[40]= 0.000161
Saving checkpoint... 
Iteration: 533252763, states[0] = -93.969849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542599909, states[0] = -93.966512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551209394, states[0] = -93.970321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559982028, states[0] = -93.973333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568961419, states[0] = -93.973631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577793719, states[0] = -93.976437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586854102, states[0] = -93.975346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595283517, states[0] = -93.989209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604332349, states[0] = -93.987624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612541830, states[0] = -93.980207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620795063, states[0] = -93.964942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629512901, states[0] = -93.967105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637715366, states[0] = -93.977852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646297933, states[0] = -93.988656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654717582, states[0] = -94.004423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663297717, states[0] = -93.670198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671901631, states[0] = -93.964171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680194010, states[0] = -93.970299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688404689, states[0] = -93.985313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696784144, states[0] = -94.005177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705269521, states[0] = -93.562763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713790202, states[0] = -93.964827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722006274, states[0] = -93.972717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730428848, states[0] = -93.984557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739089460, states[0] = -93.995941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747693824, states[0] = -94.003318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756279093, states[0] = -93.602056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764924791, states[0] = -93.963881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772865018, states[0] = -93.974863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782357570, states[0] = -93.968329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790903365, states[0] = -93.974195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798761822, states[0] = -94.004990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806982229, states[0] = -93.963475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815657218, states[0] = -93.965626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824205338, states[0] = -93.969934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832595335, states[0] = -93.980138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840791996, states[0] = -94.004910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848858518, states[0] = -93.964161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857438936, states[0] = -93.967413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866046089, states[0] = -93.971919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873857870, states[0] = -94.003791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882590802, states[0] = -93.991840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891825672, states[0] = -94.004428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899742641, states[0] = -93.964861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907695839, states[0] = -93.977821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915919438, states[0] = -94.001941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924524069, states[0] = -93.973648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932620235, states[0] = -93.965727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940780134, states[0] = -93.976112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949186151, states[0] = -93.992010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957660288, states[0] = -94.000792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966187397, states[0] = -54.345962, states[40]= 0.000149
Saving checkpoint... 
Iteration: 974448804, states[0] = -93.967135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983589370, states[0] = -93.965894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991728260, states[0] = -93.977031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999964487, states[0] = -94.000246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008463077, states[0] = -93.942652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016818449, states[0] = -93.964154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025485335, states[0] = -93.966719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033932472, states[0] = -93.973341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042287340, states[0] = -93.988372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051123030, states[0] = -93.994174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059886235, states[0] = -94.002741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068372377, states[0] = -93.846181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077012298, states[0] = 32.687885, states[40]= 0.026347
Saving checkpoint... 
Iteration: 1085589069, states[0] = -93.965734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093912711, states[0] = -93.973561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102502011, states[0] = -93.981992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111161633, states[0] = -93.992645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119583048, states[0] = -93.989937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128636980, states[0] = -93.998270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136999241, states[0] = -93.962851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145706279, states[0] = -93.964732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154339203, states[0] = -93.967925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162681784, states[0] = -93.977707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171190931, states[0] = -93.991485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179821907, states[0] = -94.004033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188702015, states[0] = -94.002997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197363107, states[0] = -93.830481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206033283, states[0] = 30.687898, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1214214377, states[0] = -93.969207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222931245, states[0] = -93.973059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231384717, states[0] = -93.985033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239915997, states[0] = -94.001539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248157894, states[0] = -31.949168, states[40]= 0.002552
Saving checkpoint... 
Iteration: 1256999113, states[0] = -93.962661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265344300, states[0] = -93.967695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273737154, states[0] = -93.976406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281937265, states[0] = -94.000760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290237404, states[0] = -93.347209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299125472, states[0] = -8.631813, states[40]= 0.003022
Saving checkpoint... 
Iteration: 1307630202, states[0] = -93.965051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316391413, states[0] = -93.967139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325114988, states[0] = -93.970258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333756939, states[0] = -93.975926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342239302, states[0] = -93.989511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350669690, states[0] = -94.000896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359384001, states[0] = -93.863253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367942673, states[0] = -93.962813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376374485, states[0] = -93.967212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384633697, states[0] = -93.978390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393579274, states[0] = -93.979620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402073496, states[0] = -93.995496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410347537, states[0] = -93.800695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418218406, states[0] = -93.968835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426781573, states[0] = -93.975311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434618389, states[0] = -93.995461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443354391, states[0] = -93.814166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451647085, states[0] = -93.964690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460298465, states[0] = -93.967868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468515071, states[0] = -93.981075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477166527, states[0] = -93.991884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485669830, states[0] = -94.000692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494579614, states[0] = -93.988624, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.838248
 - CaMKt in component CaMK (millimolar): 0.001337
 - cass in component intracellular_ions (millimolar): 0.000103
 - nai in component intracellular_ions (millimolar): 6.808936
 - nass in component intracellular_ions (millimolar): 6.809063
 - ki in component intracellular_ions (millimolar): 145.053185
 - kss in component intracellular_ions (millimolar): 145.053175
 - cansr in component intracellular_ions (millimolar): 1.844200
 - cajsr in component intracellular_ions (millimolar): 1.844009
 - cai in component intracellular_ions (millimolar): 0.000107
 - m in component INa (dimensionless): 0.004029
 - hf in component INa (dimensionless): 0.860285
 - hs in component INa (dimensionless): 0.860285
 - j in component INa (dimensionless): 0.860287
 - hsp in component INa (dimensionless): 0.689746
 - jp in component INa (dimensionless): 0.860287
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.700233
 - hLp in component INaL (dimensionless): 0.505136
 - a in component Ito (dimensionless): 0.000670
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.999222
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.999699
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999496
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005620
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000588
 - xs1 in component IKs (dimensionless): 0.015234
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997603
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:04:41 (36192): called boinc_finish(0)

</stderr_txt>
]]>


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