𝕏

Task 55462562

Name HuVeMOp_20240624185102527553_ORdGradInc_k_24-Schmidt_400-conf_406_3
Workunit 25881604
Created 1 Jul 2024, 5:48:12 UTC
Sent 1 Jul 2024, 5:48:14 UTC
Report deadline 4 Jul 2024, 5:48:14 UTC
Received 1 Jul 2024, 10:08:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232855
Run time 2 hours 34 min 34 sec
CPU time 37 min
Validate state Valid
Credit 44.31
Device peak FLOPS 6.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.52 MB
Peak swap size 5.32 MB
Peak disk usage 0.14 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Schmidt_400-conf_406.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Schmidt_400-conf_406_3_r1238161533_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624185102527553_ORdGradInc_k_24-Schmidt_400-conf_406_3_r1238161533_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 117.500670
     * GNaL_b in INaL: 0.005795
     * Gto_b in Ito: 0.070761
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032150
     * GKs_b in IKs: 0.001912
     * GK1_b in IK1: 0.144871
     * Gncx_b in INaCa_i: 0.000953
     * Pnak_b in INaK: 63.306065
     * GKb_b in IKb: 0.003957
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032742
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 7500.000000
     * CL_0 in membrane: 400.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499800000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 14881768, states[0] = -11.310655, states[40]= 0.001370
Saving checkpoint... 
Iteration: 23829488, states[0] = 26.768843, states[40]= 0.000066
Saving checkpoint... 
Iteration: 32210859, states[0] = 31.337666, states[40]= 0.049265
Saving checkpoint... 
Iteration: 40439302, states[0] = 21.507418, states[40]= 0.000007
Saving checkpoint... 
Iteration: 49104211, states[0] = -42.858929, states[40]= 0.000160
Saving checkpoint... 
Iteration: 57920570, states[0] = -63.527255, states[40]= 0.000017
Saving checkpoint... 
Iteration: 66243176, states[0] = 18.993045, states[40]= 0.000007
Saving checkpoint... 
Iteration: 74652249, states[0] = 13.297773, states[40]= 0.000026
Saving checkpoint... 
Iteration: 82730854, states[0] = -77.746183, states[40]= 0.000002
Saving checkpoint... 
Iteration: 90718645, states[0] = -62.239417, states[40]= 0.000018
Saving checkpoint... 
Iteration: 98883683, states[0] = -18.084406, states[40]= 0.000232
Saving checkpoint... 
Iteration: 107961021, states[0] = -84.607786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 116060358, states[0] = 7.392196, states[40]= 0.000076
Saving checkpoint... 
Iteration: 124912222, states[0] = -54.558291, states[40]= 0.000042
Saving checkpoint... 
Iteration: 133071056, states[0] = -2.096354, states[40]= 0.000239
Saving checkpoint... 
Iteration: 141614876, states[0] = 31.083884, states[40]= 0.011599
Saving checkpoint... 
Iteration: 149871947, states[0] = -3.087321, states[40]= 0.000251
Saving checkpoint... 
Iteration: 158317539, states[0] = -61.341074, states[40]= 0.000020
Saving checkpoint... 
Iteration: 166681458, states[0] = -15.324883, states[40]= 0.000238
Saving checkpoint... 
Iteration: 175130782, states[0] = -78.298703, states[40]= 0.000002
Saving checkpoint... 
Iteration: 183549668, states[0] = -84.391276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192083806, states[0] = -18.589614, states[40]= 0.000218
Saving checkpoint... 
Iteration: 200883181, states[0] = -17.731574, states[40]= 0.000221
Saving checkpoint... 
Iteration: 209229693, states[0] = 26.090665, states[40]= 0.000055
Saving checkpoint... 
Iteration: 217463742, states[0] = 4.640247, states[40]= 0.000114
Saving checkpoint... 
Iteration: 226224191, states[0] = 28.580265, states[40]= 0.000392
Saving checkpoint... 
Iteration: 234720487, states[0] = -65.225984, states[40]= 0.000012
Saving checkpoint... 
Iteration: 243042887, states[0] = 18.915313, states[40]= 0.000005
Saving checkpoint... 
Iteration: 251293674, states[0] = -31.692634, states[40]= 0.000226
Saving checkpoint... 
Iteration: 259093065, states[0] = -30.909665, states[40]= 0.000229
Saving checkpoint... 
Iteration: 268085474, states[0] = -20.879240, states[40]= 0.000213
Saving checkpoint... 
Iteration: 276628532, states[0] = 26.651238, states[40]= 0.000083
Saving checkpoint... 
Iteration: 284969510, states[0] = -84.710701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 293716945, states[0] = -60.624379, states[40]= 0.000021
Saving checkpoint... 
Iteration: 302212568, states[0] = 31.085202, states[40]= 0.027178
Saving checkpoint... 
Iteration: 310914980, states[0] = -58.139094, states[40]= 0.000028
Saving checkpoint... 
Iteration: 319672125, states[0] = -3.317211, states[40]= 0.000252
Saving checkpoint... 
Iteration: 328316352, states[0] = -59.867204, states[40]= 0.000023
Saving checkpoint... 
Iteration: 336850861, states[0] = 13.983513, states[40]= 0.000019
Saving checkpoint... 
Iteration: 345401637, states[0] = 38.450259, states[40]= 1.190748
Saving checkpoint... 
Iteration: 354187459, states[0] = -84.879125, states[40]= 0.000001
Saving checkpoint... 
Iteration: 362628256, states[0] = 26.783740, states[40]= 0.000092
Saving checkpoint... 
Iteration: 371355157, states[0] = -84.513729, states[40]= 0.000001
Saving checkpoint... 
Iteration: 380310918, states[0] = -53.097490, states[40]= 0.000049
Saving checkpoint... 
Iteration: 388503395, states[0] = -43.864546, states[40]= 0.000116
Saving checkpoint... 
Iteration: 397225687, states[0] = 27.952301, states[40]= 0.000229
Saving checkpoint... 
Iteration: 405384348, states[0] = -84.850091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413622592, states[0] = 29.207029, states[40]= 0.000698
Saving checkpoint... 
Iteration: 422481511, states[0] = -15.414985, states[40]= 0.000235
Saving checkpoint... 
Iteration: 430931172, states[0] = -78.677660, states[40]= 0.000002
Saving checkpoint... 
Iteration: 439763492, states[0] = -84.631942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 448021312, states[0] = 29.662684, states[40]= 0.001108
Saving checkpoint... 
Iteration: 456818165, states[0] = 30.567493, states[40]= 0.003473
Saving checkpoint... 
Iteration: 465568152, states[0] = -84.686007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 474222461, states[0] = 29.256719, states[40]= 0.000731
Saving checkpoint... 
Iteration: 482365516, states[0] = -84.654440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 490779899, states[0] = -84.805545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 499289340, states[0] = -26.039996, states[40]= 0.000226
Saving checkpoint... 
Iteration: 507701590, states[0] = -41.628163, states[40]= 0.000138
Saving checkpoint... 
Iteration: 516529253, states[0] = -76.621496, states[40]= 0.000002
Saving checkpoint... 
Iteration: 525159700, states[0] = -84.577234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 533628967, states[0] = 26.448118, states[40]= 0.000071
Saving checkpoint... 
Iteration: 542679163, states[0] = -12.163968, states[40]= 0.000261
Saving checkpoint... 
Iteration: 550941107, states[0] = -83.684014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 559553446, states[0] = -84.470319, states[40]= 0.000001
Saving checkpoint... 
Iteration: 567903782, states[0] = -44.327139, states[40]= 0.000112
Saving checkpoint... 
Iteration: 576572071, states[0] = -84.723140, states[40]= 0.000001
Saving checkpoint... 
Iteration: 584930230, states[0] = -77.694467, states[40]= 0.000002
Saving checkpoint... 
Iteration: 593638786, states[0] = 21.284360, states[40]= 0.000004
Saving checkpoint... 
Iteration: 602140306, states[0] = -83.531612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610938040, states[0] = -82.945573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 619044317, states[0] = 18.072801, states[40]= 0.000006
Saving checkpoint... 
Iteration: 627672261, states[0] = -3.453418, states[40]= 0.000253
Saving checkpoint... 
Iteration: 636323929, states[0] = -69.783714, states[40]= 0.000007
Saving checkpoint... 
Iteration: 645149316, states[0] = -84.354458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 653978879, states[0] = -84.787408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 662804328, states[0] = 32.020389, states[40]= 0.542926
Saving checkpoint... 
Iteration: 670930770, states[0] = -78.244212, states[40]= 0.000002
Saving checkpoint... 
Iteration: 679490346, states[0] = -27.349854, states[40]= 0.000229
Saving checkpoint... 
Iteration: 687593504, states[0] = -84.909396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 695593850, states[0] = -84.911567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703662542, states[0] = 5.629133, states[40]= 0.000098
Saving checkpoint... 
Iteration: 712562429, states[0] = -84.604013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 721338058, states[0] = -82.941620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 730032223, states[0] = 24.828812, states[40]= 0.000023
Saving checkpoint... 
Iteration: 738023092, states[0] = 29.024497, states[40]= 0.000582
Saving checkpoint... 
Iteration: 746973323, states[0] = -84.727339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 755878907, states[0] = -11.799729, states[40]= 0.000264
Saving checkpoint... 
Iteration: 764328746, states[0] = -75.992901, states[40]= 0.000003
Saving checkpoint... 
Iteration: 772887849, states[0] = -24.042807, states[40]= 0.000219
Saving checkpoint... 
Iteration: 781144777, states[0] = -84.104195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789223712, states[0] = 28.783363, states[40]= 0.000466
Saving checkpoint... 
Iteration: 797686273, states[0] = -21.925664, states[40]= 0.000214
Saving checkpoint... 
Iteration: 806281471, states[0] = -15.332971, states[40]= 0.000236
Saving checkpoint... 
Iteration: 814887762, states[0] = -23.923748, states[40]= 0.000219
Saving checkpoint... 
Iteration: 823370856, states[0] = -84.697160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831878393, states[0] = -11.095543, states[40]= 0.000269
Saving checkpoint... 
Iteration: 840712455, states[0] = -54.949871, states[40]= 0.000040
Saving checkpoint... 
Iteration: 849329943, states[0] = -77.346624, states[40]= 0.000002
Saving checkpoint... 
Iteration: 857721527, states[0] = -66.534669, states[40]= 0.000010
Saving checkpoint... 
Iteration: 865886728, states[0] = -22.534300, states[40]= 0.000215
Saving checkpoint... 
Iteration: 874022407, states[0] = 29.284408, states[40]= 0.000745
Saving checkpoint... 
Iteration: 881890642, states[0] = -27.722938, states[40]= 0.000230
Saving checkpoint... 
Iteration: 891138752, states[0] = -83.136265, states[40]= 0.000001
Saving checkpoint... 
Iteration: 899337117, states[0] = -82.590522, states[40]= 0.000001
Saving checkpoint... 
Iteration: 907664331, states[0] = 4.169799, states[40]= 0.000122
Saving checkpoint... 
Iteration: 916017920, states[0] = 30.630990, states[40]= 0.003795
Saving checkpoint... 
Iteration: 924267788, states[0] = 1.116707, states[40]= 0.000177
Saving checkpoint... 
Iteration: 932499160, states[0] = -38.579541, states[40]= 0.000170
Saving checkpoint... 
Iteration: 940830650, states[0] = 25.630750, states[40]= 0.000039
Saving checkpoint... 
Iteration: 949228122, states[0] = 26.858862, states[40]= 0.000096
Saving checkpoint... 
Iteration: 958158461, states[0] = -84.536249, states[40]= 0.000001
Saving checkpoint... 
Iteration: 966805280, states[0] = 30.815920, states[40]= 0.388631
Saving checkpoint... 
Iteration: 975160632, states[0] = -84.566271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 983461679, states[0] = 6.321854, states[40]= 0.000088
Saving checkpoint... 
Iteration: 991775840, states[0] = -84.740137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 999823649, states[0] = 28.812522, states[40]= 0.000476
Saving checkpoint... 
Iteration: 1007853085, states[0] = 12.529957, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1016483260, states[0] = -17.794239, states[40]= 0.000220
Saving checkpoint... 
Iteration: 1024656646, states[0] = 10.073520, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1033297900, states[0] = -36.996668, states[40]= 0.000186
Saving checkpoint... 
Iteration: 1042220840, states[0] = 29.830478, states[40]= 0.001313
Saving checkpoint... 
Iteration: 1050343431, states[0] = -83.963536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059050369, states[0] = 14.319254, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1067618479, states[0] = 30.504443, states[40]= 0.003095
Saving checkpoint... 
Iteration: 1076203937, states[0] = 32.802127, states[40]= 0.621563
Saving checkpoint... 
Iteration: 1084693641, states[0] = -31.592718, states[40]= 0.000226
Saving checkpoint... 
Iteration: 1093070150, states[0] = -1.180421, states[40]= 0.000219
Saving checkpoint... 
Iteration: 1101485891, states[0] = -21.387488, states[40]= 0.000213
Saving checkpoint... 
Iteration: 1109851795, states[0] = 13.390045, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1117922648, states[0] = -67.999323, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1126791798, states[0] = -84.873599, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1135480018, states[0] = -13.299612, states[40]= 0.000252
Saving checkpoint... 
Iteration: 1143711017, states[0] = -53.152297, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1152296908, states[0] = -35.741164, states[40]= 0.000198
Saving checkpoint... 
Iteration: 1160885807, states[0] = -21.269457, states[40]= 0.000213
Saving checkpoint... 
Iteration: 1169778595, states[0] = -84.757723, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1178191954, states[0] = -84.872130, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1186717240, states[0] = -60.907447, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1195340244, states[0] = -83.473613, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1204317277, states[0] = -60.952785, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1213041906, states[0] = 19.510474, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1221797808, states[0] = -84.912860, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1230245740, states[0] = 17.226237, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1239087265, states[0] = -23.229088, states[40]= 0.000216
Saving checkpoint... 
Iteration: 1247602569, states[0] = 36.611679, states[40]= 0.993081
Saving checkpoint... 
Iteration: 1256272164, states[0] = -3.314703, states[40]= 0.000251
Saving checkpoint... 
Iteration: 1265042529, states[0] = 19.147147, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1273344972, states[0] = -84.088980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282164428, states[0] = -84.599044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1290165813, states[0] = -84.615375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1298944216, states[0] = -84.024151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307016076, states[0] = 30.967084, states[40]= 0.007448
Saving checkpoint... 
Iteration: 1315864447, states[0] = 4.085870, states[40]= 0.000123
Saving checkpoint... 
Iteration: 1324791535, states[0] = -84.861270, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1333009086, states[0] = 30.565332, states[40]= 0.098243
Saving checkpoint... 
Iteration: 1341574931, states[0] = -84.712660, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349549754, states[0] = -84.329864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1358087121, states[0] = -23.027609, states[40]= 0.000216
Saving checkpoint... 
Iteration: 1366154340, states[0] = -84.444747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1374614071, states[0] = 31.130588, states[40]= 0.015571
Saving checkpoint... 
Iteration: 1382767558, states[0] = -84.630923, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1391493404, states[0] = -31.266446, states[40]= 0.000227
Saving checkpoint... 
Iteration: 1399977857, states[0] = -84.738581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408466982, states[0] = 1.876865, states[40]= 0.000163
Saving checkpoint... 
Iteration: 1416510443, states[0] = -52.424083, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1425571923, states[0] = -84.676986, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1434229876, states[0] = 26.024384, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1442825171, states[0] = 28.195354, states[40]= 0.000276
Saving checkpoint... 
Iteration: 1451443505, states[0] = 18.575018, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1459858755, states[0] = 8.558801, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1468343414, states[0] = -83.934408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477460907, states[0] = 6.936870, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1486155067, states[0] = -84.452078, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1494410898, states[0] = 30.913180, states[40]= 0.050319
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.789212
 - CaMKt in component CaMK (millimolar): 0.152196
 - cass in component intracellular_ions (millimolar): 0.000144
 - nai in component intracellular_ions (millimolar): 7.347987
 - nass in component intracellular_ions (millimolar): 7.348255
 - ki in component intracellular_ions (millimolar): 143.906325
 - kss in component intracellular_ions (millimolar): 143.906291
 - cansr in component intracellular_ions (millimolar): 3.004725
 - cajsr in component intracellular_ions (millimolar): 2.025445
 - cai in component intracellular_ions (millimolar): 0.000139
 - m in component INa (dimensionless): 0.010015
 - hf in component INa (dimensionless): 0.581950
 - hs in component INa (dimensionless): 0.581218
 - j in component INa (dimensionless): 0.572835
 - hsp in component INa (dimensionless): 0.332179
 - jp in component INa (dimensionless): 0.555524
 - mL in component INaL (dimensionless): 0.000338
 - hL in component INaL (dimensionless): 0.234850
 - hLp in component INaL (dimensionless): 0.096252
 - a in component Ito (dimensionless): 0.001233
 - iF in component Ito (dimensionless): 0.999231
 - iS in component Ito (dimensionless): 0.181441
 - ap in component Ito (dimensionless): 0.000628
 - iFp in component Ito (dimensionless): 0.999232
 - iSp in component Ito (dimensionless): 0.201785
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.728938
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.957850
 - jca in component ICaL (dimensionless): 0.958165
 - ffp in component ICaL (dimensionless): 0.999941
 - fcafp in component ICaL (dimensionless): 0.999998
 - nca in component ICaL (dimensionless): 0.021271
 - xrf in component IKr (dimensionless): 0.036174
 - xrs in component IKr (dimensionless): 0.835545
 - xs1 in component IKs (dimensionless): 0.520799
 - xs2 in component IKs (dimensionless): 0.001490
 - xk1 in component IK1 (dimensionless): 0.996740
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
03:04:42 (34152): called boinc_finish(0)

</stderr_txt>
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