𝕏

Task 55462560

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_EPI_4000-conf_390_3
Workunit 25872753
Created 1 Jul 2024, 5:48:12 UTC
Sent 1 Jul 2024, 5:48:14 UTC
Report deadline 4 Jul 2024, 5:48:14 UTC
Received 1 Jul 2024, 10:08:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232855
Run time 2 hours 36 min 54 sec
CPU time 37 min 16 sec
Validate state Valid
Credit 44.18
Device peak FLOPS 6.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.52 MB
Peak swap size 5.32 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_EPI_4000-conf_390.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_EPI_4000-conf_390_3_r1952007537_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_EPI_4000-conf_390_3_r1952007537_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.844207
     * GNaL_b in INaL: 0.005657
     * Gto_b in Ito: 0.075886
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033740
     * GKs_b in IKs: 0.001755
     * GK1_b in IK1: 0.142718
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 61.586352
     * GKb_b in IKb: 0.004032
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033360
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16229699, states[0] = -93.467712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24210845, states[0] = -93.253574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32050559, states[0] = 25.214167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39821117, states[0] = -93.926685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47901705, states[0] = -93.926116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56311230, states[0] = -93.746953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64471276, states[0] = -93.953012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72523949, states[0] = -93.975054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80789367, states[0] = -93.988355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89116434, states[0] = -93.975022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97091058, states[0] = -93.980020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105006487, states[0] = -93.987635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113122185, states[0] = -93.984280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121401723, states[0] = -93.974809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130417291, states[0] = -93.948727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138568606, states[0] = -94.006954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147472552, states[0] = -93.977073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156243186, states[0] = -93.492084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164814475, states[0] = -94.009558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173542425, states[0] = -93.977167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182194014, states[0] = -92.990311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190803302, states[0] = -94.011436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199487809, states[0] = -93.979830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208251258, states[0] = -93.542974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216772166, states[0] = -94.013440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225020442, states[0] = -93.999990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233088568, states[0] = -93.996450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241345520, states[0] = -93.985135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249912146, states[0] = -93.969645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258456464, states[0] = -93.980391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266907155, states[0] = -94.006265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275430801, states[0] = -93.981939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283681082, states[0] = -93.974546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292211477, states[0] = -93.260664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300597876, states[0] = -94.014031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308889652, states[0] = -94.006903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316827240, states[0] = -94.010275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325024652, states[0] = -93.999193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333842446, states[0] = -93.970351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342529150, states[0] = -94.004587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351340728, states[0] = -93.984418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359494637, states[0] = -93.979010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367435394, states[0] = -93.980848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375563797, states[0] = -93.976741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383725238, states[0] = -93.972401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392057229, states[0] = 22.480076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400259703, states[0] = -93.587548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408358692, states[0] = -93.885743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416505820, states[0] = -93.998013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425441576, states[0] = -93.979958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433419978, states[0] = -93.980597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441130313, states[0] = -93.992435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449292387, states[0] = -93.985156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457768638, states[0] = -93.970513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466215021, states[0] = -93.288369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474763357, states[0] = -94.011584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482598028, states[0] = -94.011966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490939026, states[0] = -94.002008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498899791, states[0] = -94.004139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507436679, states[0] = -93.979147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515893041, states[0] = -93.967189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524816099, states[0] = -94.008446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533134026, states[0] = -93.991160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541113571, states[0] = -93.992066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549505711, states[0] = -93.976414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558085355, states[0] = 10.417447, states[40]= 0.000023
Saving checkpoint... 
Iteration: 566247350, states[0] = -93.516911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573960583, states[0] = -93.965216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582753802, states[0] = -94.010704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590674227, states[0] = -94.012689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598788036, states[0] = -94.008980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607174563, states[0] = -93.988362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615689257, states[0] = -93.970520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623630274, states[0] = -93.971947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632889704, states[0] = -94.003120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641205334, states[0] = -93.986561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649922141, states[0] = -93.965028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658789382, states[0] = -94.008204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667102012, states[0] = -93.991144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675627409, states[0] = -93.971404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683722570, states[0] = -93.968895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692329931, states[0] = -93.828224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700553932, states[0] = -94.004746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708636122, states[0] = -94.010993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716988899, states[0] = -93.996527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725453662, states[0] = -93.975983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733731057, states[0] = -93.968096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742125165, states[0] = -23.237947, states[40]= 0.000222
Saving checkpoint... 
Iteration: 750483436, states[0] = -93.986719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759192804, states[0] = -93.985717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767948878, states[0] = -93.963116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776451488, states[0] = -93.971852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785080630, states[0] = -93.990819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793802686, states[0] = -93.965746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802078646, states[0] = 13.860137, states[40]= 0.000010
Saving checkpoint... 
Iteration: 810592247, states[0] = -94.007648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819429483, states[0] = -93.975671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827551756, states[0] = -93.971709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835482438, states[0] = -93.973735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843628743, states[0] = -93.969360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851758890, states[0] = -93.966034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860363011, states[0] = -93.887011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868788778, states[0] = -94.005733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876819028, states[0] = -94.004107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885092055, states[0] = -93.989047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893352624, states[0] = -93.977530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901611365, states[0] = -93.969140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910029653, states[0] = 26.468193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918268687, states[0] = -93.625166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926877676, states[0] = -94.000301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934846674, states[0] = -94.001932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943706507, states[0] = -93.966180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952305226, states[0] = -93.761449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961042153, states[0] = -93.990732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969819059, states[0] = -93.963292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978533040, states[0] = -93.997848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986982590, states[0] = -93.993662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995517192, states[0] = -93.970742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003491425, states[0] = -93.971447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011778559, states[0] = -93.963679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020626965, states[0] = -94.007023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029171985, states[0] = -93.983453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037703634, states[0] = -93.965126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045706898, states[0] = -93.964950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053965167, states[0] = -93.959399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061999324, states[0] = -93.958694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070346532, states[0] = -93.857121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078456865, states[0] = -93.971103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086446678, states[0] = -93.965454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094624716, states[0] = -94.006062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102722798, states[0] = -94.005642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110909936, states[0] = -93.996279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119334331, states[0] = -93.975523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127323809, states[0] = -93.975832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135616650, states[0] = -93.966199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144012689, states[0] = 22.740589, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1152246788, states[0] = -93.506354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160729515, states[0] = -94.004736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169264747, states[0] = -93.977702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177894421, states[0] = -93.959256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186396940, states[0] = -93.925482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194479807, states[0] = -93.980043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203136861, states[0] = -93.983040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211433768, states[0] = -93.970848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220007483, states[0] = 19.097227, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1228006526, states[0] = 17.793985, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1236450086, states[0] = -93.965600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244603179, states[0] = -94.003246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252885263, states[0] = -93.995992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261056929, states[0] = -93.986378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269861982, states[0] = -93.958811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277954020, states[0] = -93.956931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286737631, states[0] = -94.002959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295195237, states[0] = -93.979219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303204042, states[0] = -93.978727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311629489, states[0] = -93.963756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320017540, states[0] = 24.494755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328257781, states[0] = -93.566180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336744021, states[0] = -94.002127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345573412, states[0] = -93.964902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354427491, states[0] = -93.949847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362712561, states[0] = -94.002850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370777917, states[0] = -94.000279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379041950, states[0] = -93.985763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387641846, states[0] = -93.962520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395966055, states[0] = -93.955300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404406837, states[0] = -93.932447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412984461, states[0] = -93.988482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421706071, states[0] = -93.960482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430389862, states[0] = -93.915033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438801125, states[0] = -93.998343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446898124, states[0] = -93.992953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455273599, states[0] = -93.973927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464044250, states[0] = 25.591867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472530166, states[0] = -93.991388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481465234, states[0] = -93.966581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489976319, states[0] = -93.953990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498099477, states[0] = 1.819989, states[40]= 0.000103
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.829420
 - CaMKt in component CaMK (millimolar): 0.002356
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 7.423728
 - nass in component intracellular_ions (millimolar): 7.423867
 - ki in component intracellular_ions (millimolar): 144.250349
 - kss in component intracellular_ions (millimolar): 144.250334
 - cansr in component intracellular_ions (millimolar): 2.434070
 - cajsr in component intracellular_ions (millimolar): 2.434485
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004032
 - hf in component INa (dimensionless): 0.860111
 - hs in component INa (dimensionless): 0.860111
 - j in component INa (dimensionless): 0.860116
 - hsp in component INa (dimensionless): 0.689439
 - jp in component INa (dimensionless): 0.860118
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.700024
 - hLp in component INaL (dimensionless): 0.504488
 - a in component Ito (dimensionless): 0.000670
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.999843
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.999843
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996883
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005450
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.006958
 - xs1 in component IKs (dimensionless): 0.038297
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997605
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:07:15 (26420): called boinc_finish(0)

</stderr_txt>
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