𝕏

Task 55462559

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_431_4
Workunit 25841285
Created 1 Jul 2024, 5:48:12 UTC
Sent 1 Jul 2024, 5:48:14 UTC
Report deadline 4 Jul 2024, 5:48:14 UTC
Received 1 Jul 2024, 10:08:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232855
Run time 2 hours 31 min 49 sec
CPU time 36 min 26 sec
Validate state Valid
Credit 42.80
Device peak FLOPS 6.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.48 MB
Peak swap size 5.25 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_431.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_431_4_r133487118_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-BASE_MID-conf_431_4_r133487118_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 113.742254
     * GNaL_b in INaL: 0.007115
     * Gto_b in Ito: 0.076954
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033599
     * GKs_b in IKs: 0.001819
     * GK1_b in IK1: 0.172011
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 67.826938
     * GKb_b in IKb: 0.003919
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.053789
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 15518202, states[0] = 32.874875, states[40]= 0.000113
Saving checkpoint... 
Iteration: 23983453, states[0] = -86.979767, states[40]= 0.000002
Saving checkpoint... 
Iteration: 32170104, states[0] = -42.520753, states[40]= 0.000118
Saving checkpoint... 
Iteration: 41202341, states[0] = -85.287397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49288919, states[0] = -86.773706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 57237633, states[0] = -86.553537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65960569, states[0] = -87.029440, states[40]= 0.000002
Saving checkpoint... 
Iteration: 74741304, states[0] = -86.591346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83382425, states[0] = -86.985635, states[40]= 0.000002
Saving checkpoint... 
Iteration: 91402914, states[0] = -87.009020, states[40]= 0.000002
Saving checkpoint... 
Iteration: 100042036, states[0] = 29.284783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109050295, states[0] = 26.796535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117284467, states[0] = -86.801797, states[40]= 0.000001
Saving checkpoint... 
Iteration: 125857075, states[0] = -86.966752, states[40]= 0.000002
Saving checkpoint... 
Iteration: 134680105, states[0] = -67.231972, states[40]= 0.000007
Saving checkpoint... 
Iteration: 143115902, states[0] = -4.649581, states[40]= 0.000110
Saving checkpoint... 
Iteration: 151976091, states[0] = -87.061887, states[40]= 0.000002
Saving checkpoint... 
Iteration: 160392813, states[0] = -87.010640, states[40]= 0.000002
Saving checkpoint... 
Iteration: 169104700, states[0] = 2.439099, states[40]= 0.000054
Saving checkpoint... 
Iteration: 178062441, states[0] = 22.289610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186659427, states[0] = -42.737517, states[40]= 0.000153
Saving checkpoint... 
Iteration: 195416322, states[0] = -87.029870, states[40]= 0.000002
Saving checkpoint... 
Iteration: 203802825, states[0] = -86.860337, states[40]= 0.000001
Saving checkpoint... 
Iteration: 212291643, states[0] = -86.827670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 220867890, states[0] = -86.982067, states[40]= 0.000002
Saving checkpoint... 
Iteration: 229109554, states[0] = -0.523092, states[40]= 0.000079
Saving checkpoint... 
Iteration: 237795528, states[0] = -86.838361, states[40]= 0.000001
Saving checkpoint... 
Iteration: 246307113, states[0] = -86.869884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 255197651, states[0] = -86.070312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264052886, states[0] = 25.782669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273056398, states[0] = 24.544846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281706584, states[0] = -86.356277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290806730, states[0] = -86.866741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 299053502, states[0] = 25.570213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307313075, states[0] = -86.881655, states[40]= 0.000001
Saving checkpoint... 
Iteration: 315373775, states[0] = -86.984754, states[40]= 0.000002
Saving checkpoint... 
Iteration: 324421767, states[0] = -87.027916, states[40]= 0.000002
Saving checkpoint... 
Iteration: 333149967, states[0] = -33.768838, states[40]= 0.000303
Saving checkpoint... 
Iteration: 342000945, states[0] = 37.715909, states[40]= 1.291336
Saving checkpoint... 
Iteration: 350674649, states[0] = -60.168870, states[40]= 0.000019
Saving checkpoint... 
Iteration: 359447725, states[0] = -87.041619, states[40]= 0.000002
Saving checkpoint... 
Iteration: 367992552, states[0] = -87.059252, states[40]= 0.000002
Saving checkpoint... 
Iteration: 376697592, states[0] = -86.058348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385220150, states[0] = -86.465139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393464117, states[0] = -87.047585, states[40]= 0.000002
Saving checkpoint... 
Iteration: 402115549, states[0] = -4.600856, states[40]= 0.000110
Saving checkpoint... 
Iteration: 410801805, states[0] = -86.847518, states[40]= 0.000001
Saving checkpoint... 
Iteration: 419335900, states[0] = -86.923639, states[40]= 0.000002
Saving checkpoint... 
Iteration: 428260922, states[0] = -86.701272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 436669928, states[0] = -54.305115, states[40]= 0.000041
Saving checkpoint... 
Iteration: 445125846, states[0] = -13.097536, states[40]= 0.000124
Saving checkpoint... 
Iteration: 454040207, states[0] = 29.588578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462665444, states[0] = -49.204619, states[40]= 0.000076
Saving checkpoint... 
Iteration: 470800713, states[0] = -86.841435, states[40]= 0.000001
Saving checkpoint... 
Iteration: 479698040, states[0] = -86.089189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487820032, states[0] = -86.888351, states[40]= 0.000002
Saving checkpoint... 
Iteration: 496424365, states[0] = -87.020938, states[40]= 0.000002
Saving checkpoint... 
Iteration: 504466991, states[0] = -87.043161, states[40]= 0.000002
Saving checkpoint... 
Iteration: 513223487, states[0] = -86.482414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522178137, states[0] = -65.014093, states[40]= 0.000010
Saving checkpoint... 
Iteration: 531592131, states[0] = 9.044147, states[40]= 0.000017
Saving checkpoint... 
Iteration: 540450509, states[0] = -87.033852, states[40]= 0.000002
Saving checkpoint... 
Iteration: 549032793, states[0] = 31.165088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557940469, states[0] = -87.027663, states[40]= 0.000002
Saving checkpoint... 
Iteration: 566554367, states[0] = 25.273364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574802135, states[0] = -86.840003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 583079880, states[0] = 14.876000, states[40]= 0.000004
Saving checkpoint... 
Iteration: 591839624, states[0] = -86.921461, states[40]= 0.000002
Saving checkpoint... 
Iteration: 600831333, states[0] = -86.905807, states[40]= 0.000002
Saving checkpoint... 
Iteration: 609928077, states[0] = -87.017595, states[40]= 0.000002
Saving checkpoint... 
Iteration: 618437066, states[0] = -87.022640, states[40]= 0.000002
Saving checkpoint... 
Iteration: 627350692, states[0] = -86.937768, states[40]= 0.000002
Saving checkpoint... 
Iteration: 635651380, states[0] = -35.032378, states[40]= 0.000283
Saving checkpoint... 
Iteration: 644287821, states[0] = -86.793770, states[40]= 0.000001
Saving checkpoint... 
Iteration: 652984009, states[0] = -87.042043, states[40]= 0.000002
Saving checkpoint... 
Iteration: 661691916, states[0] = -84.572358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670884733, states[0] = -86.978783, states[40]= 0.000002
Saving checkpoint... 
Iteration: 679499175, states[0] = -87.045421, states[40]= 0.000002
Saving checkpoint... 
Iteration: 687911112, states[0] = -87.001669, states[40]= 0.000002
Saving checkpoint... 
Iteration: 696536885, states[0] = 30.371563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704749701, states[0] = -86.632394, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713808702, states[0] = -86.850068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 722425418, states[0] = -87.010163, states[40]= 0.000002
Saving checkpoint... 
Iteration: 731276548, states[0] = -86.749975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 740047998, states[0] = 27.392857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748262700, states[0] = -86.692655, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756585052, states[0] = 12.479018, states[40]= 0.000008
Saving checkpoint... 
Iteration: 765135548, states[0] = -21.517491, states[40]= 0.000190
Saving checkpoint... 
Iteration: 773637062, states[0] = -22.775174, states[40]= 0.000218
Saving checkpoint... 
Iteration: 782432106, states[0] = -87.011365, states[40]= 0.000002
Saving checkpoint... 
Iteration: 790746601, states[0] = -86.611477, states[40]= 0.000001
Saving checkpoint... 
Iteration: 799417036, states[0] = -87.000439, states[40]= 0.000002
Saving checkpoint... 
Iteration: 807865725, states[0] = -86.949724, states[40]= 0.000002
Saving checkpoint... 
Iteration: 816321645, states[0] = -86.875041, states[40]= 0.000002
Saving checkpoint... 
Iteration: 824973560, states[0] = -87.029543, states[40]= 0.000002
Saving checkpoint... 
Iteration: 833289239, states[0] = -86.788604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841685609, states[0] = -77.344691, states[40]= 0.000002
Saving checkpoint... 
Iteration: 850086700, states[0] = 11.698816, states[40]= 0.000009
Saving checkpoint... 
Iteration: 858687083, states[0] = -79.672120, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867499180, states[0] = -87.035899, states[40]= 0.000002
Saving checkpoint... 
Iteration: 875851932, states[0] = -86.926970, states[40]= 0.000002
Saving checkpoint... 
Iteration: 884291654, states[0] = -86.793569, states[40]= 0.000001
Saving checkpoint... 
Iteration: 893096581, states[0] = 6.797840, states[40]= 0.000026
Saving checkpoint... 
Iteration: 901490536, states[0] = -87.031575, states[40]= 0.000002
Saving checkpoint... 
Iteration: 910741098, states[0] = -86.574474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919270580, states[0] = -86.717114, states[40]= 0.000001
Saving checkpoint... 
Iteration: 927463545, states[0] = -87.020269, states[40]= 0.000002
Saving checkpoint... 
Iteration: 936081975, states[0] = 13.921432, states[40]= 0.000005
Saving checkpoint... 
Iteration: 944785594, states[0] = -86.770942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 953391573, states[0] = -86.971263, states[40]= 0.000002
Saving checkpoint... 
Iteration: 962141930, states[0] = -26.776337, states[40]= 0.000305
Saving checkpoint... 
Iteration: 970382007, states[0] = -86.960655, states[40]= 0.000002
Saving checkpoint... 
Iteration: 978439003, states[0] = -87.005486, states[40]= 0.000002
Saving checkpoint... 
Iteration: 987251551, states[0] = -86.627224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 996033725, states[0] = 31.010178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004452263, states[0] = -87.011177, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1012833623, states[0] = -86.889103, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1021474987, states[0] = -87.020130, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1030658692, states[0] = -42.028086, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1039261029, states[0] = -86.670088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1047858050, states[0] = -86.927144, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1056775449, states[0] = -86.729023, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065270016, states[0] = -86.707280, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1074068674, states[0] = 19.772228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1082816195, states[0] = -86.849223, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1091337072, states[0] = -86.891407, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1099921893, states[0] = -86.988624, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1108419767, states[0] = -86.986716, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1117246072, states[0] = -86.591621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126432066, states[0] = -86.993894, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1135137127, states[0] = -22.802433, states[40]= 0.000218
Saving checkpoint... 
Iteration: 1143164888, states[0] = -48.519632, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1151968664, states[0] = -87.011027, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1161207534, states[0] = -86.319802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170224549, states[0] = -86.455378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178889030, states[0] = -86.957299, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1187773787, states[0] = -86.715885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1196744172, states[0] = -86.577017, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1205381724, states[0] = -86.948406, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1214522173, states[0] = 32.087364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223160407, states[0] = -43.757002, states[40]= 0.000137
Saving checkpoint... 
Iteration: 1231952419, states[0] = -86.999720, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1240941978, states[0] = -86.993843, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1249523153, states[0] = 32.098944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258348220, states[0] = -86.901713, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1266960194, states[0] = -87.001581, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1276013371, states[0] = 30.371857, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1284991085, states[0] = -87.012342, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1293749037, states[0] = -86.598306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1303125989, states[0] = -13.159228, states[40]= 0.000122
Saving checkpoint... 
Iteration: 1312173621, states[0] = -58.697019, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1321031151, states[0] = 31.443119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329638107, states[0] = -23.596725, states[40]= 0.000236
Saving checkpoint... 
Iteration: 1338318638, states[0] = -86.841701, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1346861584, states[0] = -86.916795, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1355614162, states[0] = -3.548698, states[40]= 0.000102
Saving checkpoint... 
Iteration: 1364398799, states[0] = -86.957066, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1373251505, states[0] = -86.606928, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1382113057, states[0] = -2.779607, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1390883098, states[0] = -86.940446, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1399931335, states[0] = -86.979574, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1408719733, states[0] = -86.408262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417325736, states[0] = -86.852920, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1426106025, states[0] = 1.652712, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1434696909, states[0] = -85.915378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443096609, states[0] = 6.799987, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1451431080, states[0] = -86.976792, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1460029891, states[0] = 31.621834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468779802, states[0] = -86.723842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1477602773, states[0] = 3.505428, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1486506266, states[0] = 24.109926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495449821, states[0] = -86.985084, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.880007
 - CaMKt in component CaMK (millimolar): 0.024905
 - cass in component intracellular_ions (millimolar): 0.000092
 - nai in component intracellular_ions (millimolar): 8.126134
 - nass in component intracellular_ions (millimolar): 8.126284
 - ki in component intracellular_ions (millimolar): 143.308098
 - kss in component intracellular_ions (millimolar): 143.308059
 - cansr in component intracellular_ions (millimolar): 2.030672
 - cajsr in component intracellular_ions (millimolar): 1.964258
 - cai in component intracellular_ions (millimolar): 0.000095
 - m in component INa (dimensionless): 0.008119
 - hf in component INa (dimensionless): 0.662477
 - hs in component INa (dimensionless): 0.662450
 - j in component INa (dimensionless): 0.662294
 - hsp in component INa (dimensionless): 0.414651
 - jp in component INa (dimensionless): 0.662183
 - mL in component INaL (dimensionless): 0.000228
 - hL in component INaL (dimensionless): 0.459655
 - hLp in component INaL (dimensionless): 0.226056
 - a in component Ito (dimensionless): 0.001071
 - iF in component Ito (dimensionless): 0.999469
 - iS in component Ito (dimensionless): 0.538788
 - ap in component Ito (dimensionless): 0.000546
 - iFp in component Ito (dimensionless): 0.999469
 - iSp in component Ito (dimensionless): 0.583168
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.879074
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999633
 - jca in component ICaL (dimensionless): 0.999944
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003777
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.504022
 - xs1 in component IKs (dimensionless): 0.330036
 - xs2 in component IKs (dimensionless): 0.000216
 - xk1 in component IK1 (dimensionless): 0.997012
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
03:01:16 (37864): called boinc_finish(0)

</stderr_txt>
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