𝕏

Task 55462036

Name HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_871_2
Workunit 26099935
Created 1 Jul 2024, 4:47:11 UTC
Sent 1 Jul 2024, 4:47:17 UTC
Report deadline 4 Jul 2024, 14:23:17 UTC
Received 3 Jul 2024, 23:14:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241013
Run time 2 hours 15 min 24 sec
CPU time 2 hours 14 min 50 sec
Validate state Valid
Credit 61.03
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_871.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_871_2_r860246161_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_871_2_r860246161_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.114144
     * GNaL_b in INaL: 0.005309
     * Gto_b in Ito: 0.090857
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032496
     * GKs_b in IKs: 0.002107
     * GK1_b in IK1: 0.152036
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 73.121423
     * GKb_b in IKb: 0.003932
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019118
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11996299, states[0] = -95.061640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24024359, states[0] = 18.781750, states[40]= 0.007098
Saving checkpoint... 
Iteration: 36103904, states[0] = -28.559786, states[40]= 0.000519
Saving checkpoint... 
Iteration: 48261128, states[0] = -94.864779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60096933, states[0] = -20.592189, states[40]= 0.000926
Saving checkpoint... 
Iteration: 71934743, states[0] = -94.953725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83800866, states[0] = -94.884850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95807047, states[0] = -94.886685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107851295, states[0] = -94.913311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119631328, states[0] = -54.121437, states[40]= 0.000014
Saving checkpoint... 
Iteration: 131634971, states[0] = -58.000111, states[40]= 0.000007
Saving checkpoint... 
Iteration: 143737361, states[0] = -94.799331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155577779, states[0] = -2.996791, states[40]= 0.003803
Saving checkpoint... 
Iteration: 167688585, states[0] = -94.697784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179672269, states[0] = -94.532898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191552878, states[0] = 9.502445, states[40]= 0.004897
Saving checkpoint... 
Iteration: 203594901, states[0] = -17.571392, states[40]= 0.001170
Saving checkpoint... 
Iteration: 215441017, states[0] = -94.939948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227378162, states[0] = -94.920607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239555577, states[0] = 8.391413, states[40]= 0.004862
Saving checkpoint... 
Iteration: 251355499, states[0] = -94.910261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263461809, states[0] = -94.944016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275301568, states[0] = -94.874565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287179333, states[0] = -94.659347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299234588, states[0] = -94.792846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311374105, states[0] = -94.918740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323153151, states[0] = -81.635289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335164228, states[0] = -93.378801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347195477, states[0] = -94.713941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359070453, states[0] = 1.422636, states[40]= 0.004434
Saving checkpoint... 
Iteration: 370987742, states[0] = -94.948157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382604856, states[0] = -27.170092, states[40]= 0.000592
Saving checkpoint... 
Iteration: 394681259, states[0] = -94.670925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406685001, states[0] = -94.686129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418595417, states[0] = -18.055637, states[40]= 0.001124
Saving checkpoint... 
Iteration: 430690335, states[0] = -94.701313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442744980, states[0] = -94.809317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454244921, states[0] = -94.809220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466288912, states[0] = -94.862904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478242977, states[0] = -94.806229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490181081, states[0] = -94.669930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502336113, states[0] = -94.899298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514222828, states[0] = -94.771745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526176428, states[0] = -94.630331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538431943, states[0] = -94.937387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550335604, states[0] = -94.898956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562441117, states[0] = -94.939527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574391428, states[0] = -94.925285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586264433, states[0] = -94.835934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598359846, states[0] = -94.912094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610342369, states[0] = -94.902904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622202382, states[0] = -94.729571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634245797, states[0] = -94.810416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646086492, states[0] = -9.699541, states[40]= 0.002417
Saving checkpoint... 
Iteration: 658163052, states[0] = -92.904234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670175112, states[0] = -94.609232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682216355, states[0] = -94.759081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694377687, states[0] = -94.919949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706274285, states[0] = -94.847485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718153760, states[0] = -82.612013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730192292, states[0] = -94.706009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742027703, states[0] = 18.518229, states[40]= 0.006328
Saving checkpoint... 
Iteration: 753773273, states[0] = -94.846310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765758538, states[0] = -94.828267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777405861, states[0] = -94.929980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789212421, states[0] = -94.751022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800815359, states[0] = -94.885145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812949911, states[0] = -94.941255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825100568, states[0] = -23.033782, states[40]= 0.000788
Saving checkpoint... 
Iteration: 836908069, states[0] = -94.930622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849034242, states[0] = 16.496848, states[40]= 0.005531
Saving checkpoint... 
Iteration: 860943390, states[0] = -94.939828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872895841, states[0] = -94.926627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884699694, states[0] = -94.723330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896546135, states[0] = 12.179117, states[40]= 0.005003
Saving checkpoint... 
Iteration: 908618441, states[0] = -40.438352, states[40]= 0.000120
Saving checkpoint... 
Iteration: 920321195, states[0] = -94.889275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932083544, states[0] = -7.211840, states[40]= 0.002948
Saving checkpoint... 
Iteration: 944159819, states[0] = -90.717284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956216369, states[0] = -94.758918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968139959, states[0] = -63.421630, states[40]= 0.000003
Saving checkpoint... 
Iteration: 980303337, states[0] = -94.875538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992122497, states[0] = -44.568146, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1004289275, states[0] = -94.862883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015915618, states[0] = -94.932733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027729735, states[0] = -94.783972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039811151, states[0] = -94.881789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051846124, states[0] = -94.904704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063698882, states[0] = -94.721352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075742847, states[0] = -94.805613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087519795, states[0] = 20.421338, states[40]= 0.009697
Saving checkpoint... 
Iteration: 1099539085, states[0] = 14.813069, states[40]= 0.005231
Saving checkpoint... 
Iteration: 1111531451, states[0] = 17.400755, states[40]= 0.005793
Saving checkpoint... 
Iteration: 1123164616, states[0] = -93.505960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135141989, states[0] = -65.815827, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1147102214, states[0] = -24.621423, states[40]= 0.000712
Saving checkpoint... 
Iteration: 1158693710, states[0] = -94.709161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170756926, states[0] = -94.825844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182633760, states[0] = -56.516867, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1194629493, states[0] = -51.929291, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1206616847, states[0] = -38.846167, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1218360325, states[0] = -94.911897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230393451, states[0] = -94.925550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242452856, states[0] = -94.941562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254172383, states[0] = -94.534471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266165819, states[0] = -93.830757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278126014, states[0] = -48.238656, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1290093260, states[0] = -15.975889, states[40]= 0.001349
Saving checkpoint... 
Iteration: 1302147836, states[0] = -73.446865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314048111, states[0] = 11.412479, states[40]= 0.004966
Saving checkpoint... 
Iteration: 1326047723, states[0] = 11.564009, states[40]= 0.004973
Saving checkpoint... 
Iteration: 1337767813, states[0] = -94.839538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349542426, states[0] = 13.585633, states[40]= 0.005100
Saving checkpoint... 
Iteration: 1361480599, states[0] = -94.946403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373487286, states[0] = -94.947399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385235354, states[0] = -94.793358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397299325, states[0] = -94.871824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409250105, states[0] = -94.816208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421250306, states[0] = -94.816489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433318409, states[0] = -94.886940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445105463, states[0] = -27.755060, states[40]= 0.000564
Saving checkpoint... 
Iteration: 1457170707, states[0] = -94.452981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469124951, states[0] = -47.121453, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1480908989, states[0] = -94.930460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492921303, states[0] = -94.933986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505024283, states[0] = -95.111624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516805485, states[0] = 28.074267, states[40]= 0.124592
Saving checkpoint... 
Iteration: 1528792779, states[0] = -95.217812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540780943, states[0] = -95.219042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552175081, states[0] = -95.221083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564269986, states[0] = -7.733525, states[40]= 0.003191
Saving checkpoint... 
Iteration: 1576219273, states[0] = 20.344327, states[40]= 0.011666
Saving checkpoint... 
Iteration: 1587893829, states[0] = -95.247844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599951276, states[0] = 5.768628, states[40]= 0.005452
Saving checkpoint... 
Iteration: 1611933475, states[0] = 14.859757, states[40]= 0.006544
Saving checkpoint... 
Iteration: 1623651835, states[0] = 5.414563, states[40]= 0.005423
Saving checkpoint... 
Iteration: 1635558113, states[0] = -95.219173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647230636, states[0] = -95.184262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658991178, states[0] = -95.250258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670547401, states[0] = -94.802918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1682234913, states[0] = -89.056146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694182358, states[0] = -21.593278, states[40]= 0.000919
Saving checkpoint... 
Iteration: 1706144801, states[0] = 9.279613, states[40]= 0.005754
Saving checkpoint... 
Iteration: 1718226629, states[0] = -75.585487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730045226, states[0] = -95.204861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742069228, states[0] = -95.231564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753941054, states[0] = -93.765922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765554522, states[0] = 3.786173, states[40]= 0.005274
Saving checkpoint... 
Iteration: 1777573486, states[0] = -11.724932, states[40]= 0.002277
Saving checkpoint... 
Iteration: 1789359752, states[0] = -95.022633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801296092, states[0] = -94.949676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813399933, states[0] = -94.981103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825372559, states[0] = -94.955767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837331266, states[0] = -94.922672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849272952, states[0] = -94.864413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861121702, states[0] = -44.514566, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1873066471, states[0] = 3.279611, states[40]= 0.004610
Saving checkpoint... 
Iteration: 1885053752, states[0] = 9.049203, states[40]= 0.004886
Saving checkpoint... 
Iteration: 1896470221, states[0] = -94.948852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908551180, states[0] = 10.148505, states[40]= 0.004920
Saving checkpoint... 
Iteration: 1920579962, states[0] = -4.546593, states[40]= 0.003509
Saving checkpoint... 
Iteration: 1932346534, states[0] = -94.905822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943823614, states[0] = -94.891293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956094537, states[0] = -17.241617, states[40]= 0.001204
Saving checkpoint... 
Iteration: 1967589478, states[0] = -12.420694, states[40]= 0.001888
Saving checkpoint... 
Iteration: 1979625688, states[0] = -47.917410, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1991408301, states[0] = -94.930102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003409148, states[0] = -94.930272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015301411, states[0] = -94.873265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027200644, states[0] = -94.724722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039185183, states[0] = -94.685593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051206559, states[0] = -94.737739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062645247, states[0] = -69.905391, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2074347147, states[0] = -94.904521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086248990, states[0] = -94.814082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098059341, states[0] = 6.779808, states[40]= 0.004805
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.824465
 - CaMKt in component CaMK (millimolar): 0.007080
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.534158
 - nass in component intracellular_ions (millimolar): 6.534219
 - ki in component intracellular_ions (millimolar): 145.440776
 - kss in component intracellular_ions (millimolar): 145.440756
 - cansr in component intracellular_ions (millimolar): 1.321872
 - cajsr in component intracellular_ions (millimolar): 1.284102
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003647
 - hf in component INa (dimensionless): 0.878652
 - hs in component INa (dimensionless): 0.878646
 - j in component INa (dimensionless): 0.878614
 - hsp in component INa (dimensionless): 0.723289
 - jp in component INa (dimensionless): 0.878592
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708327
 - hLp in component INaL (dimensionless): 0.451054
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.623958
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.699483
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939155
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999897
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001637
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328622
 - xs1 in component IKs (dimensionless): 0.234152
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997357
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:37:34 (168339): called boinc_finish(0)

</stderr_txt>
]]>


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