𝕏

Task 55462031

Name HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_471_2
Workunit 26099930
Created 1 Jul 2024, 4:47:11 UTC
Sent 1 Jul 2024, 4:47:17 UTC
Report deadline 4 Jul 2024, 14:23:17 UTC
Received 3 Jul 2024, 23:14:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241013
Run time 2 hours 14 min 3 sec
CPU time 2 hours 13 min 19 sec
Validate state Valid
Credit 60.85
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_471.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_471_2_r915803117_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_471_2_r915803117_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 119.205042
     * GNaL_b in INaL: 0.006456
     * Gto_b in Ito: 0.100069
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031593
     * GKs_b in IKs: 0.002096
     * GK1_b in IK1: 0.159389
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 71.763461
     * GKb_b in IKb: 0.003817
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040400
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12300656, states[0] = -95.001511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24237505, states[0] = -94.898699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36446506, states[0] = -95.008246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48489828, states[0] = -95.003006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60611969, states[0] = -29.140927, states[40]= 0.000510
Saving checkpoint... 
Iteration: 72763801, states[0] = -94.885707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84383647, states[0] = -94.962165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96619106, states[0] = -35.094679, states[40]= 0.000257
Saving checkpoint... 
Iteration: 108941189, states[0] = -94.973282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121060222, states[0] = 7.752294, states[40]= 0.004681
Saving checkpoint... 
Iteration: 133301507, states[0] = -94.911386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145317196, states[0] = -94.922182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157477606, states[0] = -94.976443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169716119, states[0] = -94.803298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181333882, states[0] = -94.931579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193326782, states[0] = -94.927248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205490908, states[0] = -94.977505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217589135, states[0] = -7.871771, states[40]= 0.002711
Saving checkpoint... 
Iteration: 229786103, states[0] = -94.896372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241857354, states[0] = -94.943087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253829001, states[0] = -94.928279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266138757, states[0] = -54.532252, states[40]= 0.000013
Saving checkpoint... 
Iteration: 278073256, states[0] = 2.054838, states[40]= 0.004356
Saving checkpoint... 
Iteration: 290240502, states[0] = -94.842793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302198732, states[0] = -94.768392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314197442, states[0] = -94.765625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326527784, states[0] = 18.668614, states[40]= 0.006109
Saving checkpoint... 
Iteration: 338608371, states[0] = -24.914019, states[40]= 0.000713
Saving checkpoint... 
Iteration: 350686705, states[0] = -94.735307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362570323, states[0] = 3.467981, states[40]= 0.004473
Saving checkpoint... 
Iteration: 374534857, states[0] = 16.736001, states[40]= 0.005281
Saving checkpoint... 
Iteration: 386724838, states[0] = -94.817918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398625563, states[0] = -40.905349, states[40]= 0.000113
Saving checkpoint... 
Iteration: 410777212, states[0] = -94.887589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423066229, states[0] = 5.310245, states[40]= 0.004586
Saving checkpoint... 
Iteration: 435166302, states[0] = -91.205351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446862714, states[0] = -94.945241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459070707, states[0] = 3.287955, states[40]= 0.004460
Saving checkpoint... 
Iteration: 471186801, states[0] = -94.735659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483186003, states[0] = -94.731788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495351940, states[0] = -94.940328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507182586, states[0] = -94.706002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519312360, states[0] = -94.917249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531499689, states[0] = -94.978140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543465518, states[0] = -94.973396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555672759, states[0] = -94.146311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567848037, states[0] = -94.938382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579873022, states[0] = -94.949371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592036798, states[0] = 16.141566, states[40]= 0.005153
Saving checkpoint... 
Iteration: 603986782, states[0] = -94.976483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616123142, states[0] = -38.566861, states[40]= 0.000159
Saving checkpoint... 
Iteration: 628320563, states[0] = -94.922724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640334272, states[0] = -94.931035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652524648, states[0] = 19.376213, states[40]= 0.006859
Saving checkpoint... 
Iteration: 664166773, states[0] = -91.602584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676350744, states[0] = -94.939633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688293480, states[0] = -94.902488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700220987, states[0] = -94.811035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712447588, states[0] = -94.970107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724566579, states[0] = 5.157930, states[40]= 0.004578
Saving checkpoint... 
Iteration: 736790771, states[0] = -94.900115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749042755, states[0] = 14.195031, states[40]= 0.004902
Saving checkpoint... 
Iteration: 761112934, states[0] = -29.073729, states[40]= 0.000515
Saving checkpoint... 
Iteration: 773212068, states[0] = -94.794669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785395545, states[0] = -94.957127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797355862, states[0] = -94.941961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809620523, states[0] = -36.087054, states[40]= 0.000225
Saving checkpoint... 
Iteration: 821720870, states[0] = -94.810747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833897131, states[0] = -94.957590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846112089, states[0] = -28.301408, states[40]= 0.000553
Saving checkpoint... 
Iteration: 858064824, states[0] = 5.913571, states[40]= 0.004614
Saving checkpoint... 
Iteration: 870343310, states[0] = -94.935783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882722499, states[0] = -94.813559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894703673, states[0] = -94.778168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906929307, states[0] = -94.966136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918952217, states[0] = -94.970841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931170093, states[0] = -93.465455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943355757, states[0] = -94.941816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955353244, states[0] = -94.940638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967557857, states[0] = 8.733872, states[40]= 0.004704
Saving checkpoint... 
Iteration: 979766408, states[0] = -94.875701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991775446, states[0] = -94.885405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003986441, states[0] = -94.976171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016043969, states[0] = 13.780831, states[40]= 0.004870
Saving checkpoint... 
Iteration: 1028165945, states[0] = -90.877017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040314630, states[0] = -94.918481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052382197, states[0] = -94.952476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064282577, states[0] = -94.892406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076439205, states[0] = -94.968184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088208096, states[0] = -94.786814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100412880, states[0] = -94.961944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112194416, states[0] = -94.758336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124363900, states[0] = -94.945295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136452204, states[0] = -94.970694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148444153, states[0] = -94.969144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160667015, states[0] = -91.791418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172780806, states[0] = -94.890630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184783976, states[0] = -94.893649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197007701, states[0] = 22.419499, states[40]= 0.094559
Saving checkpoint... 
Iteration: 1208988628, states[0] = -94.976322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221190765, states[0] = -94.749039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233350166, states[0] = -94.938981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245243584, states[0] = -94.846582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257651548, states[0] = -69.463379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1269456695, states[0] = -94.971415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281174687, states[0] = -94.399344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293365148, states[0] = -94.945709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305183461, states[0] = -94.714021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317280204, states[0] = -94.889947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329553189, states[0] = 10.499511, states[40]= 0.004742
Saving checkpoint... 
Iteration: 1341470023, states[0] = -94.973580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353360286, states[0] = -94.943578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365596800, states[0] = -14.390145, states[40]= 0.001514
Saving checkpoint... 
Iteration: 1377521014, states[0] = 20.053324, states[40]= 0.008558
Saving checkpoint... 
Iteration: 1389689569, states[0] = -94.745374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401822817, states[0] = -94.923653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413931096, states[0] = -94.966203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426135505, states[0] = -51.056273, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1438140219, states[0] = -56.110885, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1450355509, states[0] = -94.941362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462594779, states[0] = -12.592219, states[40]= 0.001794
Saving checkpoint... 
Iteration: 1474568997, states[0] = 4.080001, states[40]= 0.004515
Saving checkpoint... 
Iteration: 1486927220, states[0] = -94.965266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499179888, states[0] = -94.662923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511123450, states[0] = 19.433838, states[40]= 0.008710
Saving checkpoint... 
Iteration: 1522744833, states[0] = -95.183950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534600126, states[0] = -34.997866, states[40]= 0.000257
Saving checkpoint... 
Iteration: 1546667212, states[0] = -95.059420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1558805354, states[0] = 27.105960, states[40]= 0.130567
Saving checkpoint... 
Iteration: 1570704320, states[0] = -95.154187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582808627, states[0] = 22.999149, states[40]= 0.074327
Saving checkpoint... 
Iteration: 1594890722, states[0] = -26.226286, states[40]= 0.000642
Saving checkpoint... 
Iteration: 1606500768, states[0] = 46.546397, states[40]= 0.008009
Saving checkpoint... 
Iteration: 1618661912, states[0] = -95.057001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630454599, states[0] = -95.232195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641759944, states[0] = -95.047235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653965048, states[0] = -1.495403, states[40]= 0.004453
Saving checkpoint... 
Iteration: 1666060752, states[0] = -95.052532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677594726, states[0] = -95.267183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689760904, states[0] = -95.053559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701879948, states[0] = -95.256399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1713477710, states[0] = -95.105679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725754534, states[0] = -94.981500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737906269, states[0] = 25.266004, states[40]= 0.117493
Saving checkpoint... 
Iteration: 1749745727, states[0] = -94.033852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761543565, states[0] = -95.220847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773681687, states[0] = -16.816479, states[40]= 0.001366
Saving checkpoint... 
Iteration: 1785332666, states[0] = 15.548648, states[40]= 0.006433
Saving checkpoint... 
Iteration: 1797332309, states[0] = 15.694823, states[40]= 0.006474
Saving checkpoint... 
Iteration: 1809448313, states[0] = -95.024840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820775099, states[0] = -94.925511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832647301, states[0] = -66.532701, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1844875804, states[0] = -94.969700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856646080, states[0] = -63.786742, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1868536397, states[0] = 16.143152, states[40]= 0.005175
Saving checkpoint... 
Iteration: 1880329868, states[0] = -94.934486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892145475, states[0] = -62.343571, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1904219080, states[0] = -94.810194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916021617, states[0] = 19.931746, states[40]= 0.008167
Saving checkpoint... 
Iteration: 1927964527, states[0] = -94.973873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940191851, states[0] = -94.752612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951984190, states[0] = -94.975962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963658805, states[0] = -80.580617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975796987, states[0] = -94.904891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987479818, states[0] = -94.974815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999468223, states[0] = -94.972986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011592879, states[0] = -10.948797, states[40]= 0.002089
Saving checkpoint... 
Iteration: 2023311175, states[0] = -94.915436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035285693, states[0] = -94.894683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047395826, states[0] = -94.956357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059439877, states[0] = -94.967639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071619575, states[0] = -35.200068, states[40]= 0.000253
Saving checkpoint... 
Iteration: 2083731344, states[0] = -94.827482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095562691, states[0] = 6.805238, states[40]= 0.004649
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.852955
 - CaMKt in component CaMK (millimolar): 0.007058
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.591993
 - nass in component intracellular_ions (millimolar): 6.592053
 - ki in component intracellular_ions (millimolar): 145.385675
 - kss in component intracellular_ions (millimolar): 145.385655
 - cansr in component intracellular_ions (millimolar): 1.310167
 - cajsr in component intracellular_ions (millimolar): 1.271745
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003636
 - hf in component INa (dimensionless): 0.879150
 - hs in component INa (dimensionless): 0.879145
 - j in component INa (dimensionless): 0.879116
 - hsp in component INa (dimensionless): 0.724228
 - jp in component INa (dimensionless): 0.879096
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707666
 - hLp in component INaL (dimensionless): 0.447688
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.617245
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.691597
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935603
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001582
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332953
 - xs1 in component IKs (dimensionless): 0.245103
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997350
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:24:55 (168325): called boinc_finish(0)

</stderr_txt>
]]>


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