𝕏

Task 55459184

Name HuVeMOp_20240629112358674907_ORdGradInc_k_25-BASE_MID-conf_83_2
Workunit 26268034
Created 30 Jun 2024, 20:55:25 UTC
Sent 30 Jun 2024, 20:55:28 UTC
Report deadline 3 Jul 2024, 20:55:28 UTC
Received 2 Jul 2024, 18:54:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 2 hours 53 min 59 sec
CPU time 2 hours 22 min 2 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-BASE_MID-conf_83.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-BASE_MID-conf_83_2_r691669045_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629112358674907_ORdGradInc_k_25-BASE_MID-conf_83_2_r691669045_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 90.524296
     * GNaL_b in INaL: 0.006621
     * Gto_b in Ito: 0.084830
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033496
     * GKs_b in IKs: 0.001980
     * GK1_b in IK1: 0.152713
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 75.279395
     * GKb_b in IKb: 0.003910
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048406
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8237647, states[0] = -86.381535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17853837, states[0] = -86.818446, states[40]= 0.000001
Saving checkpoint... 
Iteration: 26814062, states[0] = -86.750910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 35972434, states[0] = -86.969670, states[40]= 0.000002
Saving checkpoint... 
Iteration: 45026877, states[0] = 31.958790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53719271, states[0] = -86.313191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62847880, states[0] = -86.889156, states[40]= 0.000001
Saving checkpoint... 
Iteration: 71190819, states[0] = -78.370906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 80266955, states[0] = -86.655081, states[40]= 0.000001
Saving checkpoint... 
Iteration: 88718537, states[0] = -86.340134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97358158, states[0] = -86.930019, states[40]= 0.000002
Saving checkpoint... 
Iteration: 106570305, states[0] = 19.297793, states[40]= 0.000001
Saving checkpoint... 
Iteration: 115324940, states[0] = -86.869488, states[40]= 0.000001
Saving checkpoint... 
Iteration: 123747668, states[0] = -86.564951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133103003, states[0] = 3.621842, states[40]= 0.000040
Saving checkpoint... 
Iteration: 141725497, states[0] = -86.410809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151168620, states[0] = -52.401916, states[40]= 0.000042
Saving checkpoint... 
Iteration: 159620475, states[0] = -8.163729, states[40]= 0.000108
Saving checkpoint... 
Iteration: 168291204, states[0] = -86.774093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177780513, states[0] = -86.733036, states[40]= 0.000001
Saving checkpoint... 
Iteration: 186887516, states[0] = -86.978284, states[40]= 0.000002
Saving checkpoint... 
Iteration: 195334592, states[0] = -86.894190, states[40]= 0.000002
Saving checkpoint... 
Iteration: 203453017, states[0] = -87.031275, states[40]= 0.000002
Saving checkpoint... 
Iteration: 212047522, states[0] = 27.426227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220759314, states[0] = -86.632393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 229106514, states[0] = 1.494990, states[40]= 0.000055
Saving checkpoint... 
Iteration: 237655422, states[0] = -38.952116, states[40]= 0.000175
Saving checkpoint... 
Iteration: 246469915, states[0] = -87.037859, states[40]= 0.000002
Saving checkpoint... 
Iteration: 255381787, states[0] = -86.968508, states[40]= 0.000002
Saving checkpoint... 
Iteration: 264012155, states[0] = 28.864136, states[40]= -0.000000
Saving checkpoint... 
Iteration: 272842698, states[0] = -86.906978, states[40]= 0.000002
Saving checkpoint... 
Iteration: 280979537, states[0] = -87.040266, states[40]= 0.000002
Saving checkpoint... 
Iteration: 289541729, states[0] = 29.005919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298020462, states[0] = 31.331307, states[40]= -0.000000
Saving checkpoint... 
Iteration: 306651749, states[0] = -35.477220, states[40]= 0.000225
Saving checkpoint... 
Iteration: 315382147, states[0] = -86.965761, states[40]= 0.000002
Saving checkpoint... 
Iteration: 324495260, states[0] = -87.043828, states[40]= 0.000002
Saving checkpoint... 
Iteration: 332890385, states[0] = -86.974449, states[40]= 0.000002
Saving checkpoint... 
Iteration: 341333377, states[0] = -86.884277, states[40]= 0.000002
Saving checkpoint... 
Iteration: 350237263, states[0] = -86.490660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359088696, states[0] = 10.857243, states[40]= 0.000010
Saving checkpoint... 
Iteration: 367876108, states[0] = -86.955239, states[40]= 0.000002
Saving checkpoint... 
Iteration: 375966929, states[0] = -87.029562, states[40]= 0.000002
Saving checkpoint... 
Iteration: 384881249, states[0] = -86.960866, states[40]= 0.000002
Saving checkpoint... 
Iteration: 393310750, states[0] = -86.825529, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402379077, states[0] = -86.957190, states[40]= 0.000002
Saving checkpoint... 
Iteration: 411280751, states[0] = -86.722282, states[40]= 0.000001
Saving checkpoint... 
Iteration: 419169784, states[0] = -53.911250, states[40]= 0.000035
Saving checkpoint... 
Iteration: 427279937, states[0] = -86.718056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 435346980, states[0] = -86.906193, states[40]= 0.000002
Saving checkpoint... 
Iteration: 444415489, states[0] = -86.992840, states[40]= 0.000002
Saving checkpoint... 
Iteration: 453619444, states[0] = -7.407613, states[40]= 0.000106
Saving checkpoint... 
Iteration: 462278941, states[0] = -86.712015, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471432960, states[0] = -87.004763, states[40]= 0.000002
Saving checkpoint... 
Iteration: 479265249, states[0] = -86.648787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 487695410, states[0] = -84.875577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496112276, states[0] = -2.105761, states[40]= 0.000081
Saving checkpoint... 
Iteration: 504584686, states[0] = 12.767521, states[40]= 0.000007
Saving checkpoint... 
Iteration: 513769312, states[0] = -86.666456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523025980, states[0] = 31.485750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531547812, states[0] = 27.342787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540429141, states[0] = -86.998314, states[40]= 0.000002
Saving checkpoint... 
Iteration: 548995418, states[0] = -87.031732, states[40]= 0.000002
Saving checkpoint... 
Iteration: 557138265, states[0] = -23.735704, states[40]= 0.000200
Saving checkpoint... 
Iteration: 566285971, states[0] = -86.734351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574779713, states[0] = -86.708992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 583822537, states[0] = -86.846089, states[40]= 0.000001
Saving checkpoint... 
Iteration: 592666902, states[0] = -50.726788, states[40]= 0.000051
Saving checkpoint... 
Iteration: 601191586, states[0] = -82.495999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610236570, states[0] = -86.471206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618362028, states[0] = -86.921522, states[40]= 0.000002
Saving checkpoint... 
Iteration: 627120839, states[0] = -8.545405, states[40]= 0.000108
Saving checkpoint... 
Iteration: 635963619, states[0] = -87.013881, states[40]= 0.000002
Saving checkpoint... 
Iteration: 644262590, states[0] = -86.626254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 652752238, states[0] = -86.569249, states[40]= 0.000001
Saving checkpoint... 
Iteration: 660793624, states[0] = -86.757074, states[40]= 0.000001
Saving checkpoint... 
Iteration: 669545740, states[0] = 27.947522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678334008, states[0] = -86.867180, states[40]= 0.000002
Saving checkpoint... 
Iteration: 686890442, states[0] = -86.955247, states[40]= 0.000002
Saving checkpoint... 
Iteration: 695762502, states[0] = -86.622919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 704074099, states[0] = 17.547358, states[40]= 0.000002
Saving checkpoint... 
Iteration: 712767098, states[0] = -86.644862, states[40]= 0.000001
Saving checkpoint... 
Iteration: 721847635, states[0] = -86.891714, states[40]= 0.000002
Saving checkpoint... 
Iteration: 730332686, states[0] = -86.861491, states[40]= 0.000002
Saving checkpoint... 
Iteration: 739030663, states[0] = 31.109772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748263810, states[0] = -86.626668, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756852983, states[0] = -86.899276, states[40]= 0.000002
Saving checkpoint... 
Iteration: 765715639, states[0] = -86.294609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774342810, states[0] = -86.879813, states[40]= 0.000002
Saving checkpoint... 
Iteration: 782647531, states[0] = -31.609184, states[40]= 0.000265
Saving checkpoint... 
Iteration: 791173465, states[0] = -58.059903, states[40]= 0.000020
Saving checkpoint... 
Iteration: 800402413, states[0] = -86.961591, states[40]= 0.000002
Saving checkpoint... 
Iteration: 809056892, states[0] = 24.365790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818785060, states[0] = -86.716890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 827781650, states[0] = -86.702915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 835977248, states[0] = -87.009275, states[40]= 0.000002
Saving checkpoint... 
Iteration: 844787848, states[0] = -86.726089, states[40]= 0.000001
Saving checkpoint... 
Iteration: 852711103, states[0] = -86.242007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861263841, states[0] = -86.620542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 870133338, states[0] = -19.535668, states[40]= 0.000131
Saving checkpoint... 
Iteration: 878183719, states[0] = -71.749177, states[40]= 0.000003
Saving checkpoint... 
Iteration: 886669953, states[0] = -54.039609, states[40]= 0.000034
Saving checkpoint... 
Iteration: 895690201, states[0] = -81.027601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 904985409, states[0] = -87.008805, states[40]= 0.000002
Saving checkpoint... 
Iteration: 913704238, states[0] = -86.101505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922542141, states[0] = 28.916326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930891821, states[0] = -86.943520, states[40]= 0.000002
Saving checkpoint... 
Iteration: 939768016, states[0] = -86.636717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 949087734, states[0] = 11.335475, states[40]= 0.000009
Saving checkpoint... 
Iteration: 957663146, states[0] = -46.683646, states[40]= 0.000081
Saving checkpoint... 
Iteration: 966975872, states[0] = -87.001585, states[40]= 0.000002
Saving checkpoint... 
Iteration: 976150504, states[0] = -34.269954, states[40]= 0.000238
Saving checkpoint... 
Iteration: 984690967, states[0] = -81.828758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 992621909, states[0] = -9.421979, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1000751965, states[0] = -86.548240, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1009426684, states[0] = -86.971036, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1017797504, states[0] = -86.750595, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1026370909, states[0] = -86.912344, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1035622539, states[0] = -9.959102, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1045188708, states[0] = -79.146021, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1054341255, states[0] = -86.861497, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1063383779, states[0] = -86.927041, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1072585650, states[0] = 12.328967, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1080776075, states[0] = -86.665608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1089154482, states[0] = -37.980658, states[40]= 0.000187
Saving checkpoint... 
Iteration: 1097799821, states[0] = -86.753793, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1106981111, states[0] = -86.996179, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1116203021, states[0] = -86.038159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124926474, states[0] = -86.964631, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1133014868, states[0] = 30.117986, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1141578565, states[0] = 15.592189, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1150212711, states[0] = -86.243304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159202496, states[0] = -86.008246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168378321, states[0] = -86.914533, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1176938822, states[0] = -86.970439, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1185660540, states[0] = -43.961642, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1194490484, states[0] = -86.995041, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1202410307, states[0] = -86.947153, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1211216795, states[0] = -86.280142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220027909, states[0] = 31.390931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228432105, states[0] = -86.963114, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1236647103, states[0] = -31.191681, states[40]= 0.000266
Saving checkpoint... 
Iteration: 1245246271, states[0] = -86.500152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254388871, states[0] = -86.922628, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1263933647, states[0] = -86.962252, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1272230560, states[0] = -86.390241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280387176, states[0] = -86.919258, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1288459627, states[0] = -86.976510, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1297378428, states[0] = -86.907646, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1306181867, states[0] = -68.889691, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1315501606, states[0] = 29.468505, states[40]= 2.042471
Saving checkpoint... 
Iteration: 1324206826, states[0] = -86.147748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332408642, states[0] = -86.938615, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1340996705, states[0] = -86.989314, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1349028844, states[0] = 31.315732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357262656, states[0] = -86.586991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1365824449, states[0] = -86.807904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1374274422, states[0] = -86.642141, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1381986715, states[0] = -86.983509, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1390735131, states[0] = -86.417216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399341317, states[0] = -86.842775, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1407783141, states[0] = -86.676867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1416047944, states[0] = 27.322420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424977082, states[0] = -86.977333, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1433626281, states[0] = -13.225123, states[40]= 0.000106
Saving checkpoint... 
Iteration: 1442356423, states[0] = -86.867691, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1450810700, states[0] = -86.767361, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459970245, states[0] = -86.972410, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1469064099, states[0] = 21.684182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477543380, states[0] = 28.609170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486605518, states[0] = 2.121022, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1494632478, states[0] = -18.736986, states[40]= 0.000123
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.857671
 - CaMKt in component CaMK (millimolar): 0.024279
 - cass in component intracellular_ions (millimolar): 0.000091
 - nai in component intracellular_ions (millimolar): 7.890707
 - nass in component intracellular_ions (millimolar): 7.890856
 - ki in component intracellular_ions (millimolar): 143.522629
 - kss in component intracellular_ions (millimolar): 143.522589
 - cansr in component intracellular_ions (millimolar): 1.993750
 - cajsr in component intracellular_ions (millimolar): 1.925191
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.008137
 - hf in component INa (dimensionless): 0.661656
 - hs in component INa (dimensionless): 0.661625
 - j in component INa (dimensionless): 0.661446
 - hsp in component INa (dimensionless): 0.413747
 - jp in component INa (dimensionless): 0.661318
 - mL in component INaL (dimensionless): 0.000229
 - hL in component INaL (dimensionless): 0.458210
 - hLp in component INaL (dimensionless): 0.224348
 - a in component Ito (dimensionless): 0.001072
 - iF in component Ito (dimensionless): 0.999467
 - iS in component Ito (dimensionless): 0.537828
 - ap in component Ito (dimensionless): 0.000546
 - iFp in component Ito (dimensionless): 0.999467
 - iSp in component Ito (dimensionless): 0.581870
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.879478
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999639
 - jca in component ICaL (dimensionless): 0.999943
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003605
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.504505
 - xs1 in component IKs (dimensionless): 0.330256
 - xs2 in component IKs (dimensionless): 0.000216
 - xk1 in component IK1 (dimensionless): 0.997017
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
20:54:07 (6704): called boinc_finish(0)

</stderr_txt>
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