𝕏

Task 55459153

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_841_2
Workunit 26211506
Created 30 Jun 2024, 20:48:48 UTC
Sent 30 Jun 2024, 20:48:52 UTC
Report deadline 3 Jul 2024, 20:48:56 UTC
Received 2 Jul 2024, 18:44:13 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 2 hours 56 min 19 sec
CPU time 2 hours 23 min 41 sec
Validate state Valid
Credit 43.60
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_841.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_841_2_r2145482619_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_666-conf_841_2_r2145482619_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 110.992410
     * GNaL_b in INaL: 0.006092
     * Gto_b in Ito: 0.082576
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030135
     * GKs_b in IKs: 0.001875
     * GK1_b in IK1: 0.147675
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 73.941364
     * GKb_b in IKb: 0.003670
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054390
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8745535, states[0] = 3.050678, states[40]= 0.001758
Saving checkpoint... 
Iteration: 17331368, states[0] = -84.744256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 25844740, states[0] = -83.962588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34309415, states[0] = -84.672952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 42924384, states[0] = -84.516199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 51113178, states[0] = -27.598565, states[40]= 0.000351
Saving checkpoint... 
Iteration: 59814420, states[0] = -63.799909, states[40]= 0.000007
Saving checkpoint... 
Iteration: 68310710, states[0] = -84.657947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 76544536, states[0] = -84.243920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85529339, states[0] = -84.119882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94771722, states[0] = -16.043168, states[40]= 0.000440
Saving checkpoint... 
Iteration: 103213611, states[0] = -84.248309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111720448, states[0] = 19.936836, states[40]= 0.000042
Saving checkpoint... 
Iteration: 120522082, states[0] = -84.021668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128882150, states[0] = -84.250863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137831673, states[0] = -78.653634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 146707293, states[0] = 26.813969, states[40]= 0.000027
Saving checkpoint... 
Iteration: 155322814, states[0] = -84.666140, states[40]= 0.000001
Saving checkpoint... 
Iteration: 164025037, states[0] = 31.902611, states[40]= 0.005343
Saving checkpoint... 
Iteration: 172285591, states[0] = -84.574075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180753693, states[0] = 3.735570, states[40]= 0.000424
Saving checkpoint... 
Iteration: 189158838, states[0] = -68.901340, states[40]= 0.000003
Saving checkpoint... 
Iteration: 197809916, states[0] = -51.006532, states[40]= 0.000045
Saving checkpoint... 
Iteration: 207071143, states[0] = 13.545597, states[40]= 0.000122
Saving checkpoint... 
Iteration: 215735618, states[0] = 14.922563, states[40]= 0.000099
Saving checkpoint... 
Iteration: 223957272, states[0] = -84.580093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 231715126, states[0] = 25.256567, states[40]= 0.000019
Saving checkpoint... 
Iteration: 239983899, states[0] = -84.644428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 248917883, states[0] = -84.423621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 258153722, states[0] = -58.980651, states[40]= 0.000015
Saving checkpoint... 
Iteration: 267491538, states[0] = -63.506954, states[40]= 0.000008
Saving checkpoint... 
Iteration: 276138827, states[0] = -42.290968, states[40]= 0.000127
Saving checkpoint... 
Iteration: 284686976, states[0] = 30.579926, states[40]= 0.237941
Saving checkpoint... 
Iteration: 293290405, states[0] = -84.567774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301568285, states[0] = -84.318175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309850038, states[0] = -83.199872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318194733, states[0] = -83.949664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326812297, states[0] = -46.734207, states[40]= 0.000076
Saving checkpoint... 
Iteration: 335710607, states[0] = 29.249692, states[40]= 0.000147
Saving checkpoint... 
Iteration: 344129460, states[0] = -28.957780, states[40]= 0.000352
Saving checkpoint... 
Iteration: 352745177, states[0] = 13.502858, states[40]= 0.000123
Saving checkpoint... 
Iteration: 361214789, states[0] = -84.152761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369963220, states[0] = -84.573122, states[40]= 0.000001
Saving checkpoint... 
Iteration: 378022185, states[0] = 33.640427, states[40]= 0.625242
Saving checkpoint... 
Iteration: 386209246, states[0] = -84.093619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395037618, states[0] = 31.780988, states[40]= 0.003714
Saving checkpoint... 
Iteration: 403981095, states[0] = -84.616160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 412550237, states[0] = -84.148071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420772506, states[0] = -0.919720, states[40]= 0.000600
Saving checkpoint... 
Iteration: 429434682, states[0] = 2.524471, states[40]= 0.000470
Saving checkpoint... 
Iteration: 437691637, states[0] = 34.121196, states[40]= 0.669109
Saving checkpoint... 
Iteration: 446608269, states[0] = -84.482032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 455457221, states[0] = -16.841165, states[40]= 0.000426
Saving checkpoint... 
Iteration: 463577143, states[0] = -84.319419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472737479, states[0] = 20.449105, states[40]= 0.000038
Saving checkpoint... 
Iteration: 481249249, states[0] = -84.346076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489813359, states[0] = -39.362414, states[40]= 0.000174
Saving checkpoint... 
Iteration: 499080794, states[0] = 16.124914, states[40]= 0.000081
Saving checkpoint... 
Iteration: 507640401, states[0] = -84.581016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 516141862, states[0] = -32.952241, states[40]= 0.000293
Saving checkpoint... 
Iteration: 525435361, states[0] = 5.128775, states[40]= 0.000366
Saving checkpoint... 
Iteration: 534021906, states[0] = -84.681717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 543158574, states[0] = -48.953985, states[40]= 0.000058
Saving checkpoint... 
Iteration: 552239292, states[0] = -84.259564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561166456, states[0] = -56.347852, states[40]= 0.000022
Saving checkpoint... 
Iteration: 570326959, states[0] = -84.622877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 578979383, states[0] = -84.585487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 586957148, states[0] = -84.512458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 595181915, states[0] = -72.220577, states[40]= 0.000002
Saving checkpoint... 
Iteration: 604062709, states[0] = 27.147702, states[40]= 0.000031
Saving checkpoint... 
Iteration: 612440044, states[0] = 4.924893, states[40]= 0.000377
Saving checkpoint... 
Iteration: 620862482, states[0] = -82.453232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630360824, states[0] = -84.681080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 638785031, states[0] = -2.168232, states[40]= 0.000630
Saving checkpoint... 
Iteration: 647463514, states[0] = -13.152392, states[40]= 0.000519
Saving checkpoint... 
Iteration: 656213531, states[0] = -83.978754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665248415, states[0] = -84.280488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673790936, states[0] = -5.721757, states[40]= 0.000668
Saving checkpoint... 
Iteration: 682331779, states[0] = -84.618890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 691264560, states[0] = -84.369189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 699805708, states[0] = -20.100469, states[40]= 0.000380
Saving checkpoint... 
Iteration: 708425716, states[0] = 15.549983, states[40]= 0.000089
Saving checkpoint... 
Iteration: 716830101, states[0] = -44.954907, states[40]= 0.000094
Saving checkpoint... 
Iteration: 725226026, states[0] = -84.085394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734246608, states[0] = -84.243702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743275721, states[0] = -84.412573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 751854252, states[0] = -69.602583, states[40]= 0.000003
Saving checkpoint... 
Iteration: 760091100, states[0] = 17.521355, states[40]= 0.000064
Saving checkpoint... 
Iteration: 768712510, states[0] = 30.662847, states[40]= 0.149076
Saving checkpoint... 
Iteration: 777113797, states[0] = 5.625656, states[40]= 0.000347
Saving checkpoint... 
Iteration: 785960166, states[0] = -84.481744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 795204542, states[0] = -82.447812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803683736, states[0] = -84.643596, states[40]= 0.000001
Saving checkpoint... 
Iteration: 812211569, states[0] = -83.572636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820797839, states[0] = -5.308324, states[40]= 0.000673
Saving checkpoint... 
Iteration: 829248521, states[0] = -84.221908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838629937, states[0] = -84.482557, states[40]= 0.000001
Saving checkpoint... 
Iteration: 847302392, states[0] = -84.503066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 855253040, states[0] = -84.243962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863324769, states[0] = -84.573725, states[40]= 0.000001
Saving checkpoint... 
Iteration: 872318037, states[0] = -84.551973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 880775949, states[0] = 11.159569, states[40]= 0.000174
Saving checkpoint... 
Iteration: 889663191, states[0] = -84.583724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897840485, states[0] = -46.339522, states[40]= 0.000080
Saving checkpoint... 
Iteration: 907171553, states[0] = -43.490818, states[40]= 0.000111
Saving checkpoint... 
Iteration: 916434121, states[0] = 16.574391, states[40]= 0.000076
Saving checkpoint... 
Iteration: 925447399, states[0] = 9.756139, states[40]= 0.000209
Saving checkpoint... 
Iteration: 934264882, states[0] = -84.294665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942133490, states[0] = -2.129405, states[40]= 0.000628
Saving checkpoint... 
Iteration: 950406229, states[0] = 29.880567, states[40]= 0.000269
Saving checkpoint... 
Iteration: 958774678, states[0] = 13.932019, states[40]= 0.000114
Saving checkpoint... 
Iteration: 966803782, states[0] = -4.104538, states[40]= 0.000665
Saving checkpoint... 
Iteration: 975444769, states[0] = 12.556595, states[40]= 0.000141
Saving checkpoint... 
Iteration: 984020930, states[0] = -84.629336, states[40]= 0.000001
Saving checkpoint... 
Iteration: 992648085, states[0] = -84.518853, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1001579235, states[0] = -84.132384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009614744, states[0] = -84.367869, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1017456348, states[0] = 7.282745, states[40]= 0.000289
Saving checkpoint... 
Iteration: 1025743414, states[0] = 29.850099, states[40]= 0.000261
Saving checkpoint... 
Iteration: 1034019871, states[0] = -84.620587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1042264728, states[0] = -84.255912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050990701, states[0] = -84.539078, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1058939035, states[0] = -84.299969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067048035, states[0] = -84.670463, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1075247877, states[0] = -84.116865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082818530, states[0] = -13.046240, states[40]= 0.000522
Saving checkpoint... 
Iteration: 1092057702, states[0] = 34.079724, states[40]= 0.665109
Saving checkpoint... 
Iteration: 1100635854, states[0] = -84.447174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1109012169, states[0] = -84.591818, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1118796908, states[0] = 6.010871, states[40]= 0.000335
Saving checkpoint... 
Iteration: 1127509274, states[0] = -36.601965, states[40]= 0.000223
Saving checkpoint... 
Iteration: 1135603307, states[0] = -84.258316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144008067, states[0] = -84.575570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1152119426, states[0] = 13.005604, states[40]= 0.000133
Saving checkpoint... 
Iteration: 1160394293, states[0] = 34.490464, states[40]= 0.701564
Saving checkpoint... 
Iteration: 1169077600, states[0] = 31.575015, states[40]= 0.002365
Saving checkpoint... 
Iteration: 1176969402, states[0] = -84.429286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1186038626, states[0] = -84.640881, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1195489068, states[0] = -11.122255, states[40]= 0.000577
Saving checkpoint... 
Iteration: 1204522172, states[0] = -46.006171, states[40]= 0.000083
Saving checkpoint... 
Iteration: 1213033963, states[0] = -84.628323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1221884701, states[0] = -77.485477, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1230708007, states[0] = -84.641014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1238873089, states[0] = -63.058594, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1247135314, states[0] = 6.807984, states[40]= 0.000306
Saving checkpoint... 
Iteration: 1255614872, states[0] = -84.291971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263975406, states[0] = -84.435287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273174614, states[0] = -27.554699, states[40]= 0.000361
Saving checkpoint... 
Iteration: 1281472335, states[0] = 5.636904, states[40]= 0.000348
Saving checkpoint... 
Iteration: 1289934892, states[0] = -84.188234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298263496, states[0] = -84.148625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306836323, states[0] = -20.373672, states[40]= 0.000376
Saving checkpoint... 
Iteration: 1314499082, states[0] = -15.599398, states[40]= 0.000454
Saving checkpoint... 
Iteration: 1322586583, states[0] = -84.047127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331211355, states[0] = -63.416965, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1339213551, states[0] = -65.497010, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1347813578, states[0] = 2.767832, states[40]= 0.000464
Saving checkpoint... 
Iteration: 1355415786, states[0] = 32.015953, states[40]= 0.011408
Saving checkpoint... 
Iteration: 1363196633, states[0] = -45.854735, states[40]= 0.000085
Saving checkpoint... 
Iteration: 1371710863, states[0] = -84.629837, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1380213209, states[0] = -62.726687, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1387750997, states[0] = 32.016374, states[40]= 0.010405
Saving checkpoint... 
Iteration: 1396644119, states[0] = -84.411126, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1405433816, states[0] = 28.091319, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1413545568, states[0] = -59.755794, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1422011548, states[0] = -84.539073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1430702456, states[0] = -84.603801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1439587443, states[0] = -83.984361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447773388, states[0] = 26.379480, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1456610849, states[0] = -84.191755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465470456, states[0] = 11.921781, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1474075890, states[0] = 36.588408, states[40]= 0.888194
Saving checkpoint... 
Iteration: 1482569739, states[0] = -81.406813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491051892, states[0] = -84.630865, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1499515574, states[0] = -23.588824, states[40]= 0.000368
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.545879
 - CaMKt in component CaMK (millimolar): 0.036856
 - cass in component intracellular_ions (millimolar): 0.000103
 - nai in component intracellular_ions (millimolar): 6.645335
 - nass in component intracellular_ions (millimolar): 6.645488
 - ki in component intracellular_ions (millimolar): 145.046107
 - kss in component intracellular_ions (millimolar): 145.046080
 - cansr in component intracellular_ions (millimolar): 2.018098
 - cajsr in component intracellular_ions (millimolar): 1.785593
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.010262
 - hf in component INa (dimensionless): 0.572199
 - hs in component INa (dimensionless): 0.572036
 - j in component INa (dimensionless): 0.571151
 - hsp in component INa (dimensionless): 0.325179
 - jp in component INa (dimensionless): 0.570399
 - mL in component INaL (dimensionless): 0.000354
 - hL in component INaL (dimensionless): 0.341650
 - hLp in component INaL (dimensionless): 0.146978
 - a in component Ito (dimensionless): 0.001253
 - iF in component Ito (dimensionless): 0.999201
 - iS in component Ito (dimensionless): 0.358725
 - ap in component Ito (dimensionless): 0.000639
 - iFp in component Ito (dimensionless): 0.999201
 - iSp in component Ito (dimensionless): 0.391251
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.836914
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995304
 - jca in component ICaL (dimensionless): 0.997924
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005729
 - xrf in component IKr (dimensionless): 0.000501
 - xrs in component IKr (dimensionless): 0.682369
 - xs1 in component IKs (dimensionless): 0.395058
 - xs2 in component IKs (dimensionless): 0.000282
 - xk1 in component IK1 (dimensionless): 0.996790
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
20:44:06 (8872): called boinc_finish(0)

</stderr_txt>
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