𝕏

Task 55458593

Name HuVeMOp_20240630114043648578_ORdGradInc_k_25-BASE_MID-conf_441_2
Workunit 26319047
Created 30 Jun 2024, 19:52:43 UTC
Sent 30 Jun 2024, 19:52:44 UTC
Report deadline 3 Jul 2024, 19:52:44 UTC
Received 2 Jul 2024, 14:21:26 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 2 hours 57 min 59 sec
CPU time 2 hours 22 min 49 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630114043648578_ORdGradInc_k_25-BASE_MID-conf_441.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630114043648578_ORdGradInc_k_25-BASE_MID-conf_441_2_r747704802_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630114043648578_ORdGradInc_k_25-BASE_MID-conf_441_2_r747704802_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 119.553437
     * GNaL_b in INaL: 0.004503
     * Gto_b in Ito: 0.095928
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032959
     * GKs_b in IKs: 0.001978
     * GK1_b in IK1: 0.151485
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 69.650376
     * GKb_b in IKb: 0.003690
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020075
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7246364, states[0] = -86.285199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15929310, states[0] = -86.787484, states[40]= 0.000002
Saving checkpoint... 
Iteration: 23319350, states[0] = -86.627903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 30678881, states[0] = -51.746980, states[40]= 0.000075
Saving checkpoint... 
Iteration: 37949849, states[0] = -86.856771, states[40]= 0.000002
Saving checkpoint... 
Iteration: 44847461, states[0] = -86.750649, states[40]= 0.000002
Saving checkpoint... 
Iteration: 50883816, states[0] = -86.823071, states[40]= 0.000002
Saving checkpoint... 
Iteration: 59238076, states[0] = -86.319494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66746300, states[0] = -86.390248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 74640519, states[0] = -24.278564, states[40]= 0.000475
Saving checkpoint... 
Iteration: 80667323, states[0] = -49.437422, states[40]= 0.000139
Saving checkpoint... 
Iteration: 87547328, states[0] = 27.509796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95698806, states[0] = -85.247151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102300006, states[0] = -86.689931, states[40]= 0.000002
Saving checkpoint... 
Iteration: 110950643, states[0] = -86.940963, states[40]= 0.000002
Saving checkpoint... 
Iteration: 118730097, states[0] = -86.304275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 124404234, states[0] = -86.906907, states[40]= 0.000002
Saving checkpoint... 
Iteration: 132316749, states[0] = -86.751532, states[40]= 0.000002
Saving checkpoint... 
Iteration: 138182671, states[0] = -70.213762, states[40]= 0.000009
Saving checkpoint... 
Iteration: 146386033, states[0] = -86.888658, states[40]= 0.000002
Saving checkpoint... 
Iteration: 155633649, states[0] = -20.708726, states[40]= 0.000337
Saving checkpoint... 
Iteration: 163705599, states[0] = -86.022210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170763882, states[0] = -86.540197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 178515224, states[0] = 29.321166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186067747, states[0] = 20.153757, states[40]= 0.000002
Saving checkpoint... 
Iteration: 194423347, states[0] = -86.927635, states[40]= 0.000002
Saving checkpoint... 
Iteration: 202626413, states[0] = -14.464614, states[40]= 0.000239
Saving checkpoint... 
Iteration: 210766896, states[0] = -86.555392, states[40]= 0.000001
Saving checkpoint... 
Iteration: 218764854, states[0] = -86.544068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225710433, states[0] = -86.114968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232355430, states[0] = -86.840418, states[40]= 0.000002
Saving checkpoint... 
Iteration: 241324095, states[0] = -86.771234, states[40]= 0.000002
Saving checkpoint... 
Iteration: 250744904, states[0] = -86.419017, states[40]= 0.000001
Saving checkpoint... 
Iteration: 259352333, states[0] = -86.833103, states[40]= 0.000002
Saving checkpoint... 
Iteration: 268291876, states[0] = -86.666041, states[40]= 0.000002
Saving checkpoint... 
Iteration: 276311753, states[0] = -86.734130, states[40]= 0.000002
Saving checkpoint... 
Iteration: 284302970, states[0] = -86.705368, states[40]= 0.000002
Saving checkpoint... 
Iteration: 293312877, states[0] = -86.736451, states[40]= 0.000002
Saving checkpoint... 
Iteration: 301704248, states[0] = -85.976432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310391374, states[0] = -86.888940, states[40]= 0.000002
Saving checkpoint... 
Iteration: 319221032, states[0] = -86.222327, states[40]= 0.000001
Saving checkpoint... 
Iteration: 328092981, states[0] = 8.591744, states[40]= 0.000040
Saving checkpoint... 
Iteration: 337208789, states[0] = -86.083112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346235123, states[0] = -86.340414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 354660818, states[0] = -45.474549, states[40]= 0.000233
Saving checkpoint... 
Iteration: 363412060, states[0] = -86.907581, states[40]= 0.000002
Saving checkpoint... 
Iteration: 372700972, states[0] = -85.791578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381870687, states[0] = -86.856289, states[40]= 0.000002
Saving checkpoint... 
Iteration: 390918004, states[0] = -86.911230, states[40]= 0.000002
Saving checkpoint... 
Iteration: 399394581, states[0] = -86.886908, states[40]= 0.000002
Saving checkpoint... 
Iteration: 408092402, states[0] = 8.889778, states[40]= 0.000037
Saving checkpoint... 
Iteration: 416593014, states[0] = 8.577785, states[40]= 0.000040
Saving checkpoint... 
Iteration: 424367025, states[0] = -86.847818, states[40]= 0.000002
Saving checkpoint... 
Iteration: 433109563, states[0] = -0.881874, states[40]= 0.000167
Saving checkpoint... 
Iteration: 441930154, states[0] = -86.918003, states[40]= 0.000002
Saving checkpoint... 
Iteration: 450323025, states[0] = -86.754902, states[40]= 0.000002
Saving checkpoint... 
Iteration: 459006024, states[0] = 22.179277, states[40]= -0.000000
Saving checkpoint... 
Iteration: 467928922, states[0] = -86.915344, states[40]= 0.000002
Saving checkpoint... 
Iteration: 477015554, states[0] = 29.436472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485437126, states[0] = -86.920325, states[40]= 0.000002
Saving checkpoint... 
Iteration: 494342752, states[0] = -86.798781, states[40]= 0.000002
Saving checkpoint... 
Iteration: 502439310, states[0] = -86.920750, states[40]= 0.000002
Saving checkpoint... 
Iteration: 510444631, states[0] = -86.923818, states[40]= 0.000002
Saving checkpoint... 
Iteration: 518827873, states[0] = -86.762903, states[40]= 0.000002
Saving checkpoint... 
Iteration: 527307651, states[0] = -86.704820, states[40]= 0.000002
Saving checkpoint... 
Iteration: 535822529, states[0] = -86.747914, states[40]= 0.000002
Saving checkpoint... 
Iteration: 544779464, states[0] = -86.595582, states[40]= 0.000002
Saving checkpoint... 
Iteration: 552958921, states[0] = -86.929672, states[40]= 0.000002
Saving checkpoint... 
Iteration: 561484735, states[0] = -86.941452, states[40]= 0.000002
Saving checkpoint... 
Iteration: 569960935, states[0] = -86.929701, states[40]= 0.000002
Saving checkpoint... 
Iteration: 578299263, states[0] = -86.673155, states[40]= 0.000002
Saving checkpoint... 
Iteration: 586791227, states[0] = -86.642555, states[40]= 0.000002
Saving checkpoint... 
Iteration: 595050792, states[0] = 26.229180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603695259, states[0] = -84.663706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 611799112, states[0] = -86.670400, states[40]= 0.000002
Saving checkpoint... 
Iteration: 621504119, states[0] = 17.339877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 630046167, states[0] = 27.570518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638965755, states[0] = -86.927733, states[40]= 0.000002
Saving checkpoint... 
Iteration: 648158349, states[0] = -42.947364, states[40]= 0.000299
Saving checkpoint... 
Iteration: 656525965, states[0] = 30.850844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665212976, states[0] = -86.117080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674217946, states[0] = -86.168778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682250042, states[0] = -86.424893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 691302181, states[0] = -86.675842, states[40]= 0.000002
Saving checkpoint... 
Iteration: 700342278, states[0] = -86.784275, states[40]= 0.000002
Saving checkpoint... 
Iteration: 708702464, states[0] = -85.864785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717097293, states[0] = 6.350688, states[40]= 0.000060
Saving checkpoint... 
Iteration: 725973963, states[0] = -86.926079, states[40]= 0.000002
Saving checkpoint... 
Iteration: 733863123, states[0] = -86.821305, states[40]= 0.000002
Saving checkpoint... 
Iteration: 742832389, states[0] = -86.759285, states[40]= 0.000002
Saving checkpoint... 
Iteration: 751333709, states[0] = -86.761843, states[40]= 0.000002
Saving checkpoint... 
Iteration: 760210695, states[0] = -86.082048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769502213, states[0] = 21.137225, states[40]= 1.879237
Saving checkpoint... 
Iteration: 778024061, states[0] = 30.841718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787073383, states[0] = 17.807043, states[40]= 0.000004
Saving checkpoint... 
Iteration: 795933842, states[0] = -86.897760, states[40]= 0.000002
Saving checkpoint... 
Iteration: 804768382, states[0] = -86.524279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 813671574, states[0] = -56.784499, states[40]= 0.000060
Saving checkpoint... 
Iteration: 822392907, states[0] = -86.857400, states[40]= 0.000002
Saving checkpoint... 
Iteration: 830862052, states[0] = -86.813142, states[40]= 0.000002
Saving checkpoint... 
Iteration: 839886615, states[0] = -86.848552, states[40]= 0.000002
Saving checkpoint... 
Iteration: 848495525, states[0] = -86.926966, states[40]= 0.000002
Saving checkpoint... 
Iteration: 856692504, states[0] = -83.148625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864974280, states[0] = -86.917209, states[40]= 0.000002
Saving checkpoint... 
Iteration: 873264279, states[0] = -86.497749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 882031743, states[0] = 30.467657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890738149, states[0] = -86.327022, states[40]= 0.000001
Saving checkpoint... 
Iteration: 899404078, states[0] = -86.864795, states[40]= 0.000002
Saving checkpoint... 
Iteration: 908273599, states[0] = -86.543802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917360948, states[0] = -86.805649, states[40]= 0.000002
Saving checkpoint... 
Iteration: 925764478, states[0] = -86.495329, states[40]= 0.000001
Saving checkpoint... 
Iteration: 934185685, states[0] = -75.152146, states[40]= 0.000005
Saving checkpoint... 
Iteration: 943609218, states[0] = -0.622726, states[40]= 0.000162
Saving checkpoint... 
Iteration: 951447715, states[0] = -86.897168, states[40]= 0.000002
Saving checkpoint... 
Iteration: 960423972, states[0] = -86.879323, states[40]= 0.000002
Saving checkpoint... 
Iteration: 969145992, states[0] = -31.305817, states[40]= 0.000639
Saving checkpoint... 
Iteration: 978119844, states[0] = -8.608207, states[40]= 0.000241
Saving checkpoint... 
Iteration: 987858619, states[0] = -86.796988, states[40]= 0.000002
Saving checkpoint... 
Iteration: 996626582, states[0] = -14.584011, states[40]= 0.000237
Saving checkpoint... 
Iteration: 1004935499, states[0] = -86.885430, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1013376155, states[0] = -86.823184, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1021626772, states[0] = -14.752905, states[40]= 0.000237
Saving checkpoint... 
Iteration: 1029568314, states[0] = 19.930099, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1038660723, states[0] = -45.285494, states[40]= 0.000234
Saving checkpoint... 
Iteration: 1047165343, states[0] = -50.053544, states[40]= 0.000138
Saving checkpoint... 
Iteration: 1055941946, states[0] = -86.886622, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1064445033, states[0] = -86.888120, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1072623418, states[0] = -11.727678, states[40]= 0.000238
Saving checkpoint... 
Iteration: 1081488969, states[0] = -86.909442, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1090013575, states[0] = 28.653825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099378590, states[0] = -86.820975, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1107782245, states[0] = -86.570681, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1116288015, states[0] = -86.594601, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1124560267, states[0] = 23.042465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1133348169, states[0] = -86.767994, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1141712747, states[0] = -86.081671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150309540, states[0] = -86.669821, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1159210432, states[0] = -86.050786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167353897, states[0] = -86.776786, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1176408787, states[0] = -86.851553, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1185835179, states[0] = -86.736779, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1194906942, states[0] = -86.848500, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1203751526, states[0] = -86.399609, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1212116139, states[0] = -5.554145, states[40]= 0.000225
Saving checkpoint... 
Iteration: 1221117813, states[0] = -6.891415, states[40]= 0.000234
Saving checkpoint... 
Iteration: 1229701321, states[0] = -85.746689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238855880, states[0] = -86.775718, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1247993741, states[0] = -86.900460, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1256602263, states[0] = 3.628956, states[40]= 0.000094
Saving checkpoint... 
Iteration: 1265791658, states[0] = -86.599312, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1273884603, states[0] = -86.817691, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1282385010, states[0] = -86.817686, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1290896211, states[0] = -86.830771, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1299857642, states[0] = -86.774927, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1308586860, states[0] = 11.667964, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1317742487, states[0] = -86.330321, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1326732338, states[0] = -86.251990, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1335682554, states[0] = -70.439831, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1344197164, states[0] = -85.142736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353245808, states[0] = -86.351363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1361350734, states[0] = -86.758118, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1370922146, states[0] = -86.851132, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1379953743, states[0] = -86.873060, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1388426232, states[0] = -86.853380, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1397252878, states[0] = -86.395288, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1406325973, states[0] = -86.699815, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1415302659, states[0] = -86.629743, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1424296489, states[0] = -86.607232, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1433003812, states[0] = 16.346445, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1441658161, states[0] = -42.656373, states[40]= 0.000303
Saving checkpoint... 
Iteration: 1449731261, states[0] = -86.234905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1458397265, states[0] = -86.821063, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1467086404, states[0] = 11.893313, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1476031964, states[0] = 30.458591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485589140, states[0] = 10.562017, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1494185851, states[0] = -75.229745, states[40]= 0.000004
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.762246
 - CaMKt in component CaMK (millimolar): 0.026698
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 8.183599
 - nass in component intracellular_ions (millimolar): 8.183763
 - ki in component intracellular_ions (millimolar): 143.111488
 - kss in component intracellular_ions (millimolar): 143.111446
 - cansr in component intracellular_ions (millimolar): 2.167553
 - cajsr in component intracellular_ions (millimolar): 2.110267
 - cai in component intracellular_ions (millimolar): 0.000099
 - m in component INa (dimensionless): 0.008216
 - hf in component INa (dimensionless): 0.658137
 - hs in component INa (dimensionless): 0.658104
 - j in component INa (dimensionless): 0.657915
 - hsp in component INa (dimensionless): 0.409943
 - jp in component INa (dimensionless): 0.657777
 - mL in component INaL (dimensionless): 0.000233
 - hL in component INaL (dimensionless): 0.454963
 - hLp in component INaL (dimensionless): 0.222061
 - a in component Ito (dimensionless): 0.001079
 - iF in component Ito (dimensionless): 0.999458
 - iS in component Ito (dimensionless): 0.537993
 - ap in component Ito (dimensionless): 0.000550
 - iFp in component Ito (dimensionless): 0.999458
 - iSp in component Ito (dimensionless): 0.581799
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.880965
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999654
 - jca in component ICaL (dimensionless): 0.999945
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004348
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.504238
 - xs1 in component IKs (dimensionless): 0.328038
 - xs2 in component IKs (dimensionless): 0.000219
 - xk1 in component IK1 (dimensionless): 0.997040
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
16:21:17 (9572): called boinc_finish(0)

</stderr_txt>
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