𝕏

Task 55456726

Name HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_EPI-conf_896_3
Workunit 26017114
Created 30 Jun 2024, 16:35:05 UTC
Sent 30 Jun 2024, 16:35:08 UTC
Report deadline 3 Jul 2024, 16:35:08 UTC
Received 2 Jul 2024, 2:51:26 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 4 min 35 sec
CPU time 2 hours 20 min 28 sec
Validate state Valid
Credit 43.59
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_EPI-conf_896.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_EPI-conf_896_3_r397258149_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_EPI-conf_896_3_r397258149_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 119.915579
     * GNaL_b in INaL: 0.007321
     * Gto_b in Ito: 0.071330
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033831
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.162971
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 67.482713
     * GKb_b in IKb: 0.003807
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040403
     * celltype in environment: 1.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8730483, states[0] = -86.936434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17322722, states[0] = -87.092761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25967810, states[0] = -87.177009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 35358747, states[0] = -87.146991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 43985483, states[0] = -87.204303, states[40]= 0.000001
Saving checkpoint... 
Iteration: 53711913, states[0] = -86.838457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62894628, states[0] = -87.195733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 72032393, states[0] = 20.197855, states[40]= 0.000014
Saving checkpoint... 
Iteration: 80205528, states[0] = -86.819625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88802149, states[0] = -87.125056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97343999, states[0] = -87.175889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 106256007, states[0] = -87.032111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115812680, states[0] = -87.144560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124724360, states[0] = -86.922064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134065248, states[0] = 11.034946, states[40]= 0.000002
Saving checkpoint... 
Iteration: 142860875, states[0] = -87.193443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 151631970, states[0] = -56.210917, states[40]= 0.000002
Saving checkpoint... 
Iteration: 159686368, states[0] = -86.705456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168954089, states[0] = -87.233026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177092260, states[0] = -6.873253, states[40]= 0.000023
Saving checkpoint... 
Iteration: 185154365, states[0] = -85.488178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193845012, states[0] = -87.180840, states[40]= 0.000001
Saving checkpoint... 
Iteration: 202125974, states[0] = -48.187770, states[40]= 0.000005
Saving checkpoint... 
Iteration: 210598708, states[0] = -14.148721, states[40]= 0.000021
Saving checkpoint... 
Iteration: 220283466, states[0] = -87.098608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230049821, states[0] = 16.827046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239273868, states[0] = -87.078346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246603466, states[0] = -19.956010, states[40]= 0.000019
Saving checkpoint... 
Iteration: 253809496, states[0] = -87.140434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261051834, states[0] = 16.209458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269027607, states[0] = 20.291113, states[40]= 0.000082
Saving checkpoint... 
Iteration: 277605158, states[0] = -22.029804, states[40]= 0.000019
Saving checkpoint... 
Iteration: 285712189, states[0] = -86.862704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292871345, states[0] = -87.198160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302043448, states[0] = 18.462344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310659256, states[0] = -86.281001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318516886, states[0] = 19.599123, states[40]= 0.004959
Saving checkpoint... 
Iteration: 326199337, states[0] = -86.788942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333588152, states[0] = -3.017685, states[40]= 0.000020
Saving checkpoint... 
Iteration: 341569346, states[0] = 9.067433, states[40]= 0.000003
Saving checkpoint... 
Iteration: 349457128, states[0] = -87.229765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 357594243, states[0] = -8.988290, states[40]= 0.000024
Saving checkpoint... 
Iteration: 366622287, states[0] = -43.363881, states[40]= 0.000008
Saving checkpoint... 
Iteration: 374920106, states[0] = -87.219050, states[40]= 0.000001
Saving checkpoint... 
Iteration: 383467182, states[0] = -87.230898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 392129054, states[0] = -52.298743, states[40]= 0.000003
Saving checkpoint... 
Iteration: 400683907, states[0] = -86.681925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409581054, states[0] = 2.352743, states[40]= 0.000011
Saving checkpoint... 
Iteration: 417859900, states[0] = -87.187300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 426878669, states[0] = -87.199185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 435935200, states[0] = -87.222210, states[40]= 0.000001
Saving checkpoint... 
Iteration: 442868974, states[0] = -87.192878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450600904, states[0] = -16.813937, states[40]= 0.000020
Saving checkpoint... 
Iteration: 457858785, states[0] = -87.185479, states[40]= 0.000001
Saving checkpoint... 
Iteration: 465184670, states[0] = -86.685935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473919074, states[0] = -87.216203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 482521373, states[0] = 20.100752, states[40]= 0.000870
Saving checkpoint... 
Iteration: 489950778, states[0] = -87.224830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 498208907, states[0] = -86.839856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505877103, states[0] = -87.196287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 513995657, states[0] = -87.231932, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523207089, states[0] = -86.829237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533122806, states[0] = -44.032392, states[40]= 0.000008
Saving checkpoint... 
Iteration: 541875108, states[0] = -87.194200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 550105836, states[0] = -22.852704, states[40]= 0.000019
Saving checkpoint... 
Iteration: 557387424, states[0] = -87.200650, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564417172, states[0] = -87.213258, states[40]= 0.000001
Saving checkpoint... 
Iteration: 572175125, states[0] = -86.607591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579825581, states[0] = -87.152163, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587724345, states[0] = -86.912926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596636476, states[0] = -62.660475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 604455749, states[0] = -87.223056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 612189229, states[0] = -86.715008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621561033, states[0] = 12.825785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 630450374, states[0] = -87.221201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637834664, states[0] = -87.160267, states[40]= 0.000001
Saving checkpoint... 
Iteration: 645857358, states[0] = -87.179680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 655039247, states[0] = 19.268230, states[40]= 0.000001
Saving checkpoint... 
Iteration: 662867227, states[0] = -87.186189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 670168708, states[0] = -86.543084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678945948, states[0] = -87.218925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 687585879, states[0] = -1.135497, states[40]= 0.000017
Saving checkpoint... 
Iteration: 696547546, states[0] = 17.470406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704539851, states[0] = 19.167011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 711784517, states[0] = -87.088276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721736839, states[0] = -86.959692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728723587, states[0] = -86.905972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736618407, states[0] = -38.385863, states[40]= 0.000013
Saving checkpoint... 
Iteration: 744250428, states[0] = -87.004638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753225921, states[0] = -86.915507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761564770, states[0] = 11.225915, states[40]= 0.000002
Saving checkpoint... 
Iteration: 768657318, states[0] = -86.076147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776540822, states[0] = 18.994442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 783263168, states[0] = -87.039187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790368377, states[0] = -87.183729, states[40]= 0.000001
Saving checkpoint... 
Iteration: 799320867, states[0] = -87.141192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808050762, states[0] = 16.548732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816091038, states[0] = -5.656755, states[40]= 0.000023
Saving checkpoint... 
Iteration: 824170392, states[0] = -86.557301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832068273, states[0] = 9.598339, states[40]= 0.000003
Saving checkpoint... 
Iteration: 839656922, states[0] = -86.019532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844869809, states[0] = -87.183279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 853228945, states[0] = -86.925631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861855305, states[0] = -87.172677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 869863793, states[0] = -87.178650, states[40]= 0.000001
Saving checkpoint... 
Iteration: 877988626, states[0] = -87.221871, states[40]= 0.000001
Saving checkpoint... 
Iteration: 885628415, states[0] = -51.424260, states[40]= 0.000004
Saving checkpoint... 
Iteration: 893090003, states[0] = -4.668281, states[40]= 0.000022
Saving checkpoint... 
Iteration: 900786124, states[0] = -87.086519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909836290, states[0] = -87.154997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917091430, states[0] = -6.039154, states[40]= 0.000023
Saving checkpoint... 
Iteration: 925827981, states[0] = -87.146057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 934558907, states[0] = 13.684124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 941849337, states[0] = -87.165906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950370216, states[0] = -87.180878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 959679662, states[0] = -86.634710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968075115, states[0] = 6.012146, states[40]= 0.000006
Saving checkpoint... 
Iteration: 976331836, states[0] = -87.148854, states[40]= 0.000001
Saving checkpoint... 
Iteration: 984341179, states[0] = -87.157734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 992281234, states[0] = -87.074747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000552175, states[0] = 16.106746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008655978, states[0] = -85.855460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017369569, states[0] = -87.178775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1026312967, states[0] = -87.125589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034770654, states[0] = -87.050954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041998827, states[0] = -87.219028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1049389816, states[0] = -87.189464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1058163436, states[0] = -86.444792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066237029, states[0] = -86.951581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074048528, states[0] = 17.205045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081191287, states[0] = -86.717098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089055958, states[0] = 14.806878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1096506048, states[0] = 13.808100, states[40]= 0.355465
Saving checkpoint... 
Iteration: 1104365416, states[0] = -87.173844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111485102, states[0] = -87.215506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1119728623, states[0] = -86.917477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127237703, states[0] = -86.952483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135062352, states[0] = 12.280790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1142193313, states[0] = -86.729201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150876702, states[0] = -87.179792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1159106587, states[0] = -23.754119, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1167108898, states[0] = -26.580887, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1174551202, states[0] = 16.416397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181817017, states[0] = -87.126838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191219284, states[0] = -86.874466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199552122, states[0] = 16.125654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208283628, states[0] = -87.073971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216414345, states[0] = -87.195817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1224232372, states[0] = -86.929878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232892223, states[0] = -87.186025, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1239900340, states[0] = -87.189592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1248715199, states[0] = -86.853224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256891078, states[0] = -87.184861, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1264459291, states[0] = -87.207193, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273469776, states[0] = -87.208976, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1281918596, states[0] = -87.195691, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1289618551, states[0] = -38.551991, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1296914119, states[0] = -87.193707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1304880598, states[0] = -87.178146, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1312612032, states[0] = -30.423629, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1320525448, states[0] = 20.291145, states[40]= 0.000185
Saving checkpoint... 
Iteration: 1328643282, states[0] = -73.488866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335505418, states[0] = 13.026366, states[40]= 0.446477
Saving checkpoint... 
Iteration: 1344142559, states[0] = -72.273940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351843457, states[0] = -87.150511, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1360577035, states[0] = 4.899616, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1368223381, states[0] = -86.888651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376148081, states[0] = -80.859483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384432948, states[0] = -87.197688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1392326226, states[0] = -87.132345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1400339241, states[0] = -87.145431, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1408531377, states[0] = 20.162955, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1415392552, states[0] = -87.181585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1423656170, states[0] = -85.876860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432002499, states[0] = 19.207842, states[40]= 1.229995
Saving checkpoint... 
Iteration: 1440217458, states[0] = -86.859370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449871838, states[0] = -87.169305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1456687066, states[0] = -86.677697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464301067, states[0] = -87.097589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472984177, states[0] = -87.206277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1480568517, states[0] = 9.487112, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1489964064, states[0] = -87.202468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1497936282, states[0] = -87.195780, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.083516
 - CaMKt in component CaMK (millimolar): 0.017836
 - cass in component intracellular_ions (millimolar): 0.000079
 - nai in component intracellular_ions (millimolar): 7.313048
 - nass in component intracellular_ions (millimolar): 7.313149
 - ki in component intracellular_ions (millimolar): 144.309505
 - kss in component intracellular_ions (millimolar): 144.309469
 - cansr in component intracellular_ions (millimolar): 2.138577
 - cajsr in component intracellular_ions (millimolar): 2.084680
 - cai in component intracellular_ions (millimolar): 0.000081
 - m in component INa (dimensionless): 0.007955
 - hf in component INa (dimensionless): 0.669914
 - hs in component INa (dimensionless): 0.669903
 - j in component INa (dimensionless): 0.669836
 - hsp in component INa (dimensionless): 0.422846
 - jp in component INa (dimensionless): 0.669786
 - mL in component INaL (dimensionless): 0.000219
 - hL in component INaL (dimensionless): 0.474017
 - hLp in component INaL (dimensionless): 0.246835
 - a in component Ito (dimensionless): 0.001056
 - iF in component Ito (dimensionless): 0.999488
 - iS in component Ito (dimensionless): 0.999453
 - ap in component Ito (dimensionless): 0.000538
 - iFp in component Ito (dimensionless): 0.999488
 - iSp in component Ito (dimensionless): 0.999479
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930466
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999897
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002133
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.366807
 - xs1 in component IKs (dimensionless): 0.259273
 - xs2 in component IKs (dimensionless): 0.000211
 - xk1 in component IK1 (dimensionless): 0.996962
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
04:50:58 (8980): called boinc_finish(0)

</stderr_txt>
]]>


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