𝕏

Task 55456724

Name HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_ENDO-conf_796_3
Workunit 26017112
Created 30 Jun 2024, 16:35:05 UTC
Sent 30 Jun 2024, 16:35:08 UTC
Report deadline 3 Jul 2024, 16:35:08 UTC
Received 2 Jul 2024, 1:44:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 4 min 44 sec
CPU time 2 hours 20 min 42 sec
Validate state Valid
Credit 45.22
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_ENDO-conf_796.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_ENDO-conf_796_3_r1657149095_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_ENDO-conf_796_3_r1657149095_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 109.913850
     * GNaL_b in INaL: 0.007132
     * Gto_b in Ito: 0.077541
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032162
     * GKs_b in IKs: 0.001768
     * GK1_b in IK1: 0.166798
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 68.835717
     * GKb_b in IKb: 0.003919
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052307
     * celltype in environment: 0.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7437247, states[0] = -87.182702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14973135, states[0] = -87.138145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22337398, states[0] = -87.036659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30773318, states[0] = -86.923444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39187999, states[0] = -86.634632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47250088, states[0] = -86.848426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54761226, states[0] = -86.870235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63126595, states[0] = -41.074639, states[40]= 0.000236
Saving checkpoint... 
Iteration: 71395619, states[0] = -87.027275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80296437, states[0] = -86.927132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88573461, states[0] = 7.376264, states[40]= 0.003753
Saving checkpoint... 
Iteration: 96573764, states[0] = 7.243154, states[40]= 0.003774
Saving checkpoint... 
Iteration: 104162702, states[0] = -83.791292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111841785, states[0] = -86.978277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120047704, states[0] = 18.907430, states[40]= 0.001975
Saving checkpoint... 
Iteration: 127887491, states[0] = -87.012474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136149809, states[0] = -67.592954, states[40]= 0.000004
Saving checkpoint... 
Iteration: 145300085, states[0] = -86.924593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153813884, states[0] = -86.943760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162481720, states[0] = -87.047875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170879803, states[0] = -87.005730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179220035, states[0] = -86.730652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187504180, states[0] = 32.271322, states[40]= 0.309570
Saving checkpoint... 
Iteration: 195661018, states[0] = -82.299829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204218565, states[0] = -86.725038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212841864, states[0] = -86.974396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221111042, states[0] = -24.092577, states[40]= 0.000957
Saving checkpoint... 
Iteration: 229499695, states[0] = -87.050644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237866206, states[0] = -86.995221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245778538, states[0] = -86.885931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253791622, states[0] = -86.909301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262683085, states[0] = -86.569549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271587807, states[0] = -1.299729, states[40]= 0.003883
Saving checkpoint... 
Iteration: 279786610, states[0] = -86.900579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288188295, states[0] = -86.600415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296775516, states[0] = -86.879761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305183129, states[0] = -86.569657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313868112, states[0] = -86.996255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322914526, states[0] = -87.023777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331212799, states[0] = -86.703043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340345882, states[0] = -86.977518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349104892, states[0] = -17.574198, states[40]= 0.001274
Saving checkpoint... 
Iteration: 357627174, states[0] = -40.926042, states[40]= 0.000243
Saving checkpoint... 
Iteration: 365610096, states[0] = -23.093415, states[40]= 0.000984
Saving checkpoint... 
Iteration: 374167819, states[0] = -85.736385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382038463, states[0] = 22.568043, states[40]= 0.001469
Saving checkpoint... 
Iteration: 390541461, states[0] = 21.410412, states[40]= 0.001618
Saving checkpoint... 
Iteration: 398911851, states[0] = -87.022197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407252217, states[0] = -86.826703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415303224, states[0] = -86.926744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424077965, states[0] = 5.052005, states[40]= 0.003972
Saving checkpoint... 
Iteration: 433171769, states[0] = -86.268168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440966132, states[0] = -87.041924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449620463, states[0] = -33.880963, states[40]= 0.000546
Saving checkpoint... 
Iteration: 458664311, states[0] = -84.552077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467333572, states[0] = -86.964674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475672331, states[0] = -86.308435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484470561, states[0] = -87.042930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492574238, states[0] = 7.093979, states[40]= 0.003817
Saving checkpoint... 
Iteration: 500512678, states[0] = 29.133759, states[40]= 0.018181
Saving checkpoint... 
Iteration: 508946301, states[0] = -87.035620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517050151, states[0] = 17.956816, states[40]= 0.002149
Saving checkpoint... 
Iteration: 524982433, states[0] = -87.045678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533171174, states[0] = -86.217848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541622293, states[0] = -35.786787, states[40]= 0.000450
Saving checkpoint... 
Iteration: 550530411, states[0] = 25.498024, states[40]= 0.001183
Saving checkpoint... 
Iteration: 558474097, states[0] = -87.043533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567673748, states[0] = -86.387539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576543053, states[0] = 20.787551, states[40]= 0.001705
Saving checkpoint... 
Iteration: 585354407, states[0] = -86.984155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593414029, states[0] = -87.022426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601600363, states[0] = -12.748641, states[40]= 0.001907
Saving checkpoint... 
Iteration: 609828260, states[0] = -86.958262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618136721, states[0] = -51.403499, states[40]= 0.000055
Saving checkpoint... 
Iteration: 626860791, states[0] = -86.989288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635733416, states[0] = -86.772663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644332506, states[0] = -86.962802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653658141, states[0] = -79.142356, states[40]= 0.000001
Saving checkpoint... 
Iteration: 662352668, states[0] = -86.982332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671346284, states[0] = -86.976526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680692286, states[0] = -86.617614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688550921, states[0] = 17.644884, states[40]= 0.002202
Saving checkpoint... 
Iteration: 697477035, states[0] = -87.043691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705692888, states[0] = -86.620210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714621283, states[0] = -34.732894, states[40]= 0.000502
Saving checkpoint... 
Iteration: 723233922, states[0] = -86.773867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731311433, states[0] = -86.936998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738916706, states[0] = -87.023062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746223041, states[0] = -86.738237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753662746, states[0] = -83.640074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762052687, states[0] = 16.924468, states[40]= 0.002327
Saving checkpoint... 
Iteration: 770073927, states[0] = 7.258468, states[40]= 0.003801
Saving checkpoint... 
Iteration: 777929014, states[0] = -87.028161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786292758, states[0] = -86.908917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794022414, states[0] = 27.866144, states[40]= 0.001543
Saving checkpoint... 
Iteration: 802065815, states[0] = 11.248592, states[40]= 0.003296
Saving checkpoint... 
Iteration: 809916062, states[0] = -87.022477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818335837, states[0] = -86.965614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826282784, states[0] = -86.891415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834075244, states[0] = 6.558195, states[40]= 0.003865
Saving checkpoint... 
Iteration: 841870384, states[0] = -86.995746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850029090, states[0] = 25.938836, states[40]= 0.001163
Saving checkpoint... 
Iteration: 858533613, states[0] = 24.375639, states[40]= 0.001271
Saving checkpoint... 
Iteration: 866835432, states[0] = -86.964992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875102010, states[0] = -14.491015, states[40]= 0.001634
Saving checkpoint... 
Iteration: 884096983, states[0] = -9.277909, states[40]= 0.002559
Saving checkpoint... 
Iteration: 892877769, states[0] = -87.000718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901440644, states[0] = -87.032052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909926587, states[0] = -87.026634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917710450, states[0] = -86.691635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926452148, states[0] = -87.035814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932982329, states[0] = -87.043981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941678815, states[0] = -86.522567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948798316, states[0] = -86.917126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956943705, states[0] = -87.032898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965201293, states[0] = -86.654976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973588137, states[0] = -1.542711, states[40]= 0.003859
Saving checkpoint... 
Iteration: 982059571, states[0] = 14.034789, states[40]= 0.002837
Saving checkpoint... 
Iteration: 991540437, states[0] = 21.809204, states[40]= 0.001565
Saving checkpoint... 
Iteration: 1000172337, states[0] = -86.306210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008470605, states[0] = -87.040793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016652899, states[0] = -71.809532, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1025373053, states[0] = -86.996910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032973797, states[0] = -87.041512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041398591, states[0] = -87.012779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050423752, states[0] = -87.024874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058769328, states[0] = -86.863884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066751366, states[0] = -86.821777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074630291, states[0] = -44.271072, states[40]= 0.000155
Saving checkpoint... 
Iteration: 1082489219, states[0] = -87.044900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089180214, states[0] = -86.539868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096670572, states[0] = -86.155912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104260140, states[0] = -86.843193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112629532, states[0] = -43.449135, states[40]= 0.000174
Saving checkpoint... 
Iteration: 1121281002, states[0] = -86.886893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129314136, states[0] = -86.938945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136349085, states[0] = -86.977190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145284139, states[0] = -86.892560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153495908, states[0] = -87.045991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160655932, states[0] = -76.171595, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1169394963, states[0] = -87.010234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177437300, states[0] = -87.029708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184806835, states[0] = -86.928775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192521005, states[0] = 28.188277, states[40]= 0.001898
Saving checkpoint... 
Iteration: 1200444348, states[0] = -87.032120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207252877, states[0] = -86.825054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214902061, states[0] = -87.013930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221966369, states[0] = -87.038786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229486576, states[0] = -87.043723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238393311, states[0] = -87.009006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246266366, states[0] = -86.856718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254325593, states[0] = -86.952555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262605554, states[0] = -18.276635, states[40]= 0.001215
Saving checkpoint... 
Iteration: 1270661529, states[0] = -82.714700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278830204, states[0] = -86.957674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286316956, states[0] = -86.941935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293193560, states[0] = -86.620724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302153823, states[0] = -73.142116, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1310195372, states[0] = -86.628574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318195027, states[0] = -86.627045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323759177, states[0] = -86.840012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329153361, states[0] = -72.472793, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1336884617, states[0] = -87.003360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345181189, states[0] = -86.548910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351834008, states[0] = -86.961493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359262817, states[0] = -86.848320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368104548, states[0] = -17.200537, states[40]= 0.001309
Saving checkpoint... 
Iteration: 1375872519, states[0] = -86.995089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384130589, states[0] = -44.592821, states[40]= 0.000149
Saving checkpoint... 
Iteration: 1391816388, states[0] = -86.940775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399239128, states[0] = -86.786725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408571381, states[0] = 8.568015, states[40]= 0.003660
Saving checkpoint... 
Iteration: 1416293894, states[0] = -86.908170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423277599, states[0] = -86.879161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431267888, states[0] = -86.859258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439467687, states[0] = -87.038252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447248251, states[0] = -86.812033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455068850, states[0] = 9.815147, states[40]= 0.003502
Saving checkpoint... 
Iteration: 1462942495, states[0] = -87.030402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471922658, states[0] = -87.022679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480521305, states[0] = 28.123296, states[40]= 0.001806
Saving checkpoint... 
Iteration: 1488029451, states[0] = 25.820876, states[40]= 0.001167
Saving checkpoint... 
Iteration: 1497279428, states[0] = -86.882368, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.921243
 - CaMKt in component CaMK (millimolar): 0.011895
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.547833
 - nass in component intracellular_ions (millimolar): 6.547925
 - ki in component intracellular_ions (millimolar): 145.344672
 - kss in component intracellular_ions (millimolar): 145.344650
 - cansr in component intracellular_ions (millimolar): 1.607689
 - cajsr in component intracellular_ions (millimolar): 1.564561
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.008085
 - hf in component INa (dimensionless): 0.663991
 - hs in component INa (dimensionless): 0.663973
 - j in component INa (dimensionless): 0.663870
 - hsp in component INa (dimensionless): 0.416329
 - jp in component INa (dimensionless): 0.663798
 - mL in component INaL (dimensionless): 0.000226
 - hL in component INaL (dimensionless): 0.467018
 - hLp in component INaL (dimensionless): 0.239150
 - a in component Ito (dimensionless): 0.001068
 - iF in component Ito (dimensionless): 0.999473
 - iS in component Ito (dimensionless): 0.570681
 - ap in component Ito (dimensionless): 0.000544
 - iFp in component Ito (dimensionless): 0.999473
 - iSp in component Ito (dimensionless): 0.620599
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.915024
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999834
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002805
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.461982
 - xs1 in component IKs (dimensionless): 0.270692
 - xs2 in component IKs (dimensionless): 0.000215
 - xk1 in component IK1 (dimensionless): 0.997002
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:44:03 (13148): called boinc_finish(0)

</stderr_txt>
]]>


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