𝕏

Task 55456723

Name HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_ENDO-conf_596_3
Workunit 26017111
Created 30 Jun 2024, 16:35:05 UTC
Sent 30 Jun 2024, 16:35:08 UTC
Report deadline 3 Jul 2024, 16:35:08 UTC
Received 2 Jul 2024, 2:53:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 6 min 18 sec
CPU time 2 hours 20 min 6 sec
Validate state Valid
Credit 43.42
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_ENDO-conf_596.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_ENDO-conf_596_3_r62215840_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_ENDO-conf_596_3_r62215840_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 94.781469
     * GNaL_b in INaL: 0.005595
     * Gto_b in Ito: 0.089233
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032680
     * GKs_b in IKs: 0.001778
     * GK1_b in IK1: 0.161483
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 62.470523
     * GKb_b in IKb: 0.004021
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050929
     * celltype in environment: 0.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 7975338, states[0] = -86.942694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16728796, states[0] = -86.606875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24430681, states[0] = -86.872695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32940539, states[0] = -86.869917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41028143, states[0] = 25.368014, states[40]= 0.000527
Saving checkpoint... 
Iteration: 49887465, states[0] = -86.837752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58615849, states[0] = -30.685140, states[40]= 0.000562
Saving checkpoint... 
Iteration: 67228856, states[0] = -86.558891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76133308, states[0] = -49.315269, states[40]= 0.000062
Saving checkpoint... 
Iteration: 84546845, states[0] = 18.491187, states[40]= 0.000931
Saving checkpoint... 
Iteration: 93839963, states[0] = -86.793370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102049322, states[0] = 17.489604, states[40]= 0.001035
Saving checkpoint... 
Iteration: 110389954, states[0] = -86.835859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119032190, states[0] = 24.088865, states[40]= 0.000528
Saving checkpoint... 
Iteration: 127550439, states[0] = 17.036356, states[40]= 0.001086
Saving checkpoint... 
Iteration: 135975267, states[0] = -86.872660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143814387, states[0] = -86.759961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152271846, states[0] = -86.681764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160217391, states[0] = -86.512422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169982235, states[0] = -86.874106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178726147, states[0] = -86.546196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187353955, states[0] = -86.806275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196858491, states[0] = -86.810425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206117204, states[0] = -32.004204, states[40]= 0.000511
Saving checkpoint... 
Iteration: 215594263, states[0] = -7.520321, states[40]= 0.002320
Saving checkpoint... 
Iteration: 224117453, states[0] = -32.267229, states[40]= 0.000501
Saving checkpoint... 
Iteration: 232600435, states[0] = -13.903825, states[40]= 0.001414
Saving checkpoint... 
Iteration: 239273126, states[0] = -86.684022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247550753, states[0] = 16.911502, states[40]= 0.001101
Saving checkpoint... 
Iteration: 255087764, states[0] = -1.965167, states[40]= 0.002880
Saving checkpoint... 
Iteration: 262642206, states[0] = -59.211695, states[40]= 0.000013
Saving checkpoint... 
Iteration: 271181118, states[0] = -86.322945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278808615, states[0] = -86.750368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286660030, states[0] = -81.503128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295215485, states[0] = -86.503759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303253825, states[0] = -86.635072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310883117, states[0] = -86.829488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319500937, states[0] = 37.705973, states[40]= 0.220452
Saving checkpoint... 
Iteration: 327842721, states[0] = -86.794080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336497420, states[0] = -86.876591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344315299, states[0] = -86.759924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353072963, states[0] = 7.004545, states[40]= 0.002423
Saving checkpoint... 
Iteration: 361860137, states[0] = -86.810943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370564528, states[0] = 11.018865, states[40]= 0.001875
Saving checkpoint... 
Iteration: 379138739, states[0] = -55.249257, states[40]= 0.000025
Saving checkpoint... 
Iteration: 387375615, states[0] = -86.823571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396633596, states[0] = -49.547289, states[40]= 0.000060
Saving checkpoint... 
Iteration: 405989821, states[0] = -86.874522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414444898, states[0] = -86.861129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422592727, states[0] = -6.082107, states[40]= 0.002513
Saving checkpoint... 
Iteration: 431290277, states[0] = -86.718314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436875958, states[0] = -86.823558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444519507, states[0] = 27.462552, states[40]= 0.002065
Saving checkpoint... 
Iteration: 451695589, states[0] = -86.414299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460212094, states[0] = -86.488706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468469049, states[0] = -86.868790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477566265, states[0] = 10.228543, states[40]= 0.001988
Saving checkpoint... 
Iteration: 485227370, states[0] = -86.548902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493631678, states[0] = -47.451508, states[40]= 0.000081
Saving checkpoint... 
Iteration: 501320362, states[0] = -86.766109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508854641, states[0] = -86.805077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516436495, states[0] = -86.857291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524877592, states[0] = -86.824299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534154994, states[0] = -75.613317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542377046, states[0] = -86.823794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550542060, states[0] = 20.414180, states[40]= 0.000762
Saving checkpoint... 
Iteration: 559860599, states[0] = -86.810257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568859764, states[0] = -86.809462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577045959, states[0] = 18.862477, states[40]= 0.000899
Saving checkpoint... 
Iteration: 586248325, states[0] = -86.617675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595021728, states[0] = 27.069182, states[40]= 0.001156
Saving checkpoint... 
Iteration: 602659010, states[0] = -80.491384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611094633, states[0] = -7.873471, states[40]= 0.002270
Saving checkpoint... 
Iteration: 618541370, states[0] = 20.684911, states[40]= 0.000740
Saving checkpoint... 
Iteration: 626644162, states[0] = -61.512223, states[40]= 0.000009
Saving checkpoint... 
Iteration: 635196271, states[0] = -86.416544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643964868, states[0] = -86.866585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652997768, states[0] = -86.874919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660826637, states[0] = -86.773460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668427908, states[0] = -86.852798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676303789, states[0] = -86.740531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685242797, states[0] = -86.600268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694404142, states[0] = -86.840684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701570070, states[0] = 8.436764, states[40]= 0.002237
Saving checkpoint... 
Iteration: 709105428, states[0] = -19.368329, states[40]= 0.000929
Saving checkpoint... 
Iteration: 717780812, states[0] = -86.698011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725924048, states[0] = -86.850729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734360224, states[0] = -86.808957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742372626, states[0] = -86.819297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750080078, states[0] = 3.132993, states[40]= 0.002808
Saving checkpoint... 
Iteration: 758376667, states[0] = -86.822315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767045362, states[0] = 19.102664, states[40]= 0.000876
Saving checkpoint... 
Iteration: 774634461, states[0] = -50.492907, states[40]= 0.000052
Saving checkpoint... 
Iteration: 781986953, states[0] = -86.871775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789676430, states[0] = -86.238992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797395513, states[0] = -86.834994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805146424, states[0] = -64.264842, states[40]= 0.000006
Saving checkpoint... 
Iteration: 811750820, states[0] = -86.623698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818597470, states[0] = -10.733412, states[40]= 0.001847
Saving checkpoint... 
Iteration: 827549479, states[0] = 17.435165, states[40]= 0.001043
Saving checkpoint... 
Iteration: 831461153, states[0] = -86.864404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837940494, states[0] = -86.857111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846321698, states[0] = -86.765993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853379988, states[0] = -86.824247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861115246, states[0] = -29.920105, states[40]= 0.000594
Saving checkpoint... 
Iteration: 869705487, states[0] = -86.457731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876967229, states[0] = -86.866005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884345261, states[0] = -86.793679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891960634, states[0] = -86.863907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899917357, states[0] = -86.846564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907387470, states[0] = -86.829186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914875048, states[0] = -86.820220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923183037, states[0] = -86.337838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930646143, states[0] = -63.914848, states[40]= 0.000006
Saving checkpoint... 
Iteration: 937778473, states[0] = -86.691856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945607945, states[0] = -22.106309, states[40]= 0.000815
Saving checkpoint... 
Iteration: 952720831, states[0] = -86.521466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960896086, states[0] = -86.834445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969305533, states[0] = -86.741702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977492389, states[0] = -86.871956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985143887, states[0] = -61.179358, states[40]= 0.000010
Saving checkpoint... 
Iteration: 992447844, states[0] = -86.859021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000977908, states[0] = -86.868299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008629627, states[0] = -45.222051, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1017814062, states[0] = -86.754397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025729838, states[0] = -86.554816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033659455, states[0] = -80.936743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042838169, states[0] = -86.785120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050786996, states[0] = -86.708594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058205205, states[0] = -86.455408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066281268, states[0] = -86.697013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073999137, states[0] = -86.872886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080968736, states[0] = -86.865321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088840837, states[0] = -86.787822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097287847, states[0] = -86.709982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104207756, states[0] = -86.466414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112212605, states[0] = -86.487173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120976089, states[0] = -86.867154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128080337, states[0] = 2.981260, states[40]= 0.002818
Saving checkpoint... 
Iteration: 1136484796, states[0] = -86.869300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144876941, states[0] = -86.820383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152235619, states[0] = -86.574245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160582444, states[0] = 1.694263, states[40]= 0.002887
Saving checkpoint... 
Iteration: 1167276039, states[0] = -86.685311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176694904, states[0] = -86.406856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184514959, states[0] = 27.838530, states[40]= 0.008646
Saving checkpoint... 
Iteration: 1193368747, states[0] = -86.813696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201073827, states[0] = 6.566152, states[40]= 0.002476
Saving checkpoint... 
Iteration: 1209640275, states[0] = -56.977767, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1218478038, states[0] = -86.867134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226789533, states[0] = -86.712480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235365678, states[0] = -86.810916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243450150, states[0] = -86.858461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251786909, states[0] = -86.707304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259519221, states[0] = 27.505962, states[40]= 0.002242
Saving checkpoint... 
Iteration: 1267056435, states[0] = 14.545029, states[40]= 0.001388
Saving checkpoint... 
Iteration: 1273904941, states[0] = -86.837934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281463117, states[0] = -86.862533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289178040, states[0] = -86.272250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298534711, states[0] = 23.204616, states[40]= 0.000569
Saving checkpoint... 
Iteration: 1306868612, states[0] = -86.812957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315413557, states[0] = -86.842348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322767258, states[0] = -86.664244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331071320, states[0] = 7.828416, states[40]= 0.002317
Saving checkpoint... 
Iteration: 1338606147, states[0] = -20.148628, states[40]= 0.000890
Saving checkpoint... 
Iteration: 1345308093, states[0] = -86.743628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353503733, states[0] = 30.398204, states[40]= 0.391120
Saving checkpoint... 
Iteration: 1361768801, states[0] = -86.667717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369745530, states[0] = -86.604881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378183825, states[0] = -86.341705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386417079, states[0] = -86.843739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394502764, states[0] = 33.488664, states[40]= 0.521846
Saving checkpoint... 
Iteration: 1401804996, states[0] = -86.738439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410046207, states[0] = 18.764303, states[40]= 0.000908
Saving checkpoint... 
Iteration: 1418838032, states[0] = -86.782881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426662107, states[0] = -83.153219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435160201, states[0] = -81.639339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443150824, states[0] = -69.944749, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1451879635, states[0] = -86.820679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460380937, states[0] = -86.821576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467896441, states[0] = -86.831861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476443281, states[0] = -86.854660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484860644, states[0] = -86.805176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492686582, states[0] = -86.360345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499449561, states[0] = -86.856839, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.746593
 - CaMKt in component CaMK (millimolar): 0.012513
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.820324
 - nass in component intracellular_ions (millimolar): 6.820418
 - ki in component intracellular_ions (millimolar): 145.054590
 - kss in component intracellular_ions (millimolar): 145.054568
 - cansr in component intracellular_ions (millimolar): 1.641011
 - cajsr in component intracellular_ions (millimolar): 1.596435
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.008229
 - hf in component INa (dimensionless): 0.657559
 - hs in component INa (dimensionless): 0.657539
 - j in component INa (dimensionless): 0.657426
 - hsp in component INa (dimensionless): 0.409367
 - jp in component INa (dimensionless): 0.657347
 - mL in component INaL (dimensionless): 0.000233
 - hL in component INaL (dimensionless): 0.461257
 - hLp in component INaL (dimensionless): 0.235094
 - a in component Ito (dimensionless): 0.001080
 - iF in component Ito (dimensionless): 0.999457
 - iS in component Ito (dimensionless): 0.570783
 - ap in component Ito (dimensionless): 0.000551
 - iFp in component Ito (dimensionless): 0.999457
 - iSp in component Ito (dimensionless): 0.620690
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.918070
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999848
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002955
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.451805
 - xs1 in component IKs (dimensionless): 0.267243
 - xs2 in component IKs (dimensionless): 0.000219
 - xk1 in component IK1 (dimensionless): 0.997044
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:53:19 (13880): called boinc_finish(0)

</stderr_txt>
]]>


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