𝕏

Task 55456530

Name HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0
Workunit 26334147
Created 30 Jun 2024, 16:20:45 UTC
Sent 30 Jun 2024, 16:21:00 UTC
Report deadline 4 Jul 2024, 1:57:00 UTC
Received 2 Jul 2024, 10:50:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213867
Run time 1 hours 32 min 52 sec
CPU time 1 hours 29 min 24 sec
Validate state Valid
Credit 66.77
Device peak FLOPS 3.98 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.72 MB
Peak swap size 6.25 MB
Peak disk usage 0.31 MB

Stderr output

<core_client_version>7.16.11</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 21398959, states[0] = -95.091917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42421913, states[0] = -95.070029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63563559, states[0] = 3.754554, states[40]= 0.004599
Saving checkpoint... 
Iteration: 85261492, states[0] = -94.960390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106696183, states[0] = -94.853372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127622553, states[0] = -47.683778, states[40]= 0.000039
Saving checkpoint... 
Iteration: 148866424, states[0] = -95.026812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170526721, states[0] = 18.286644, states[40]= 0.006173
Saving checkpoint... 
Iteration: 192773470, states[0] = -94.965814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214667952, states[0] = -94.727537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235944254, states[0] = -95.047788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258594329, states[0] = -18.997903, states[40]= 0.001031
Saving checkpoint... 
Iteration: 278011845, states[0] = 21.211224, states[40]= 0.033050


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 278011845
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 21.211224 (After loading)
 - states[40]: 0.033050 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 307097159, states[0] = -21.796464, states[40]= 0.000838


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 307097159
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -21.796464 (After loading)
 - states[40]: 0.000838 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 336506661, states[0] = 23.537432, states[40]= 0.115765


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 336506661
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 23.537432 (After loading)
 - states[40]: 0.115765 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 366344053, states[0] = -95.015592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385437007, states[0] = -95.046141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405526840, states[0] = 18.260486, states[40]= 0.006152
Saving checkpoint... 
Iteration: 425354872, states[0] = -95.020618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445849466, states[0] = -95.018133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466060125, states[0] = 5.704756, states[40]= 0.004697


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 466060125
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 5.704756 (After loading)
 - states[40]: 0.004697 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 498338437, states[0] = -95.012643, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 498338437
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.012643 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 528645895, states[0] = -76.913267, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 528645895
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -76.913267 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 557716079, states[0] = -94.887707, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 557716079
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.887707 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 590211647, states[0] = -94.879643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609009492, states[0] = 21.756512, states[40]= 0.058292


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 609009492
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 21.756512 (After loading)
 - states[40]: 0.058292 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 638723100, states[0] = -94.899709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657366613, states[0] = -95.025387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677011103, states[0] = 21.347712, states[40]= 0.039333


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 677011103
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 21.347712 (After loading)
 - states[40]: 0.039333 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 705390319, states[0] = -95.033815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724814520, states[0] = -94.998451, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 724814520
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.998451 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 754262651, states[0] = -94.953724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773652346, states[0] = -88.081173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793759606, states[0] = -94.950264, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 793759606
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.950264 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 822705657, states[0] = -94.868072, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 822705657
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.868072 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 854782071, states[0] = -94.973176, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 854782071
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.973176 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 881678560, states[0] = -94.808009, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 881678560
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.808009 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 912348334, states[0] = -95.017247, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 912348334
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.017247 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 944255923, states[0] = -94.945855, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 944255923
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.945855 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 977185164, states[0] = -94.824520, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 977185164
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.824520 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1009318304, states[0] = -95.000677, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1009318304
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.000677 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1038756449, states[0] = -94.946406, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1038756449
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.946406 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1069229474, states[0] = -94.909637, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1069229474
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.909637 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630182040266756_ORdGradInc_k_25-Pueyo_APDR-conf_738_0_r588458372_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1069229474
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.909637 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1096275891, states[0] = -94.967193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119333141, states[0] = -95.009343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142004244, states[0] = 28.698010, states[40]= 0.171019
Saving checkpoint... 
Iteration: 1164732557, states[0] = -94.914294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188322082, states[0] = -95.002891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210569716, states[0] = 0.906749, states[40]= 0.004345
Saving checkpoint... 
Iteration: 1231664497, states[0] = -94.595136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253997377, states[0] = -95.055040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276591339, states[0] = -16.046913, states[40]= 0.001334
Saving checkpoint... 
Iteration: 1296951753, states[0] = -95.048304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316538724, states[0] = 14.379680, states[40]= 0.005072
Saving checkpoint... 
Iteration: 1337927787, states[0] = -95.043429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358547537, states[0] = 11.022217, states[40]= 0.004855
Saving checkpoint... 
Iteration: 1381024624, states[0] = 18.849862, states[40]= 0.006655
Saving checkpoint... 
Iteration: 1402840212, states[0] = -95.012875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425264290, states[0] = -94.955017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448233636, states[0] = -94.915700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470774332, states[0] = -94.965388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493837925, states[0] = -95.011623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516563447, states[0] = -2.151092, states[40]= 0.004362
Saving checkpoint... 
Iteration: 1539950292, states[0] = 5.927999, states[40]= 0.005372
Saving checkpoint... 
Iteration: 1563096763, states[0] = -39.787656, states[40]= 0.000130
Saving checkpoint... 
Iteration: 1586786987, states[0] = -28.818792, states[40]= 0.000491
Saving checkpoint... 
Iteration: 1609486381, states[0] = -95.312126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632636490, states[0] = 12.847799, states[40]= 0.006049
Saving checkpoint... 
Iteration: 1656053294, states[0] = 3.726680, states[40]= 0.005199
Saving checkpoint... 
Iteration: 1679473694, states[0] = -13.771653, states[40]= 0.001866
Saving checkpoint... 
Iteration: 1702340731, states[0] = -94.818562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724730107, states[0] = 15.745439, states[40]= 0.006668
Saving checkpoint... 
Iteration: 1748057289, states[0] = -95.289761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771482937, states[0] = -95.311543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794383046, states[0] = -24.528575, states[40]= 0.000713
Saving checkpoint... 
Iteration: 1817263563, states[0] = -94.992867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840593868, states[0] = -19.726006, states[40]= 0.000976
Saving checkpoint... 
Iteration: 1864024182, states[0] = 18.853234, states[40]= 0.006757
Saving checkpoint... 
Iteration: 1886688173, states[0] = -94.835870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909474457, states[0] = -95.054090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932872970, states[0] = -95.028130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956085285, states[0] = -10.327350, states[40]= 0.002283
Saving checkpoint... 
Iteration: 1978874372, states[0] = -95.027640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001563981, states[0] = 3.883060, states[40]= 0.004601
Saving checkpoint... 
Iteration: 2024501300, states[0] = 46.690433, states[40]= 0.056787
Saving checkpoint... 
Iteration: 2047485784, states[0] = -95.052978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070097668, states[0] = -22.299535, states[40]= 0.000809
Saving checkpoint... 
Iteration: 2093214672, states[0] = -94.883967, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.930525
 - CaMKt in component CaMK (millimolar): 0.007119
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.594707
 - nass in component intracellular_ions (millimolar): 6.594768
 - ki in component intracellular_ions (millimolar): 145.378247
 - kss in component intracellular_ions (millimolar): 145.378227
 - cansr in component intracellular_ions (millimolar): 1.327244
 - cajsr in component intracellular_ions (millimolar): 1.289631
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003608
 - hf in component INa (dimensionless): 0.880497
 - hs in component INa (dimensionless): 0.880493
 - j in component INa (dimensionless): 0.880464
 - hsp in component INa (dimensionless): 0.726767
 - jp in component INa (dimensionless): 0.880445
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712202
 - hLp in component INaL (dimensionless): 0.457572
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.628338
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.705188
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.941730
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999906
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001662
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.306894
 - xs1 in component IKs (dimensionless): 0.229134
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997330
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:50:11 (5984): called boinc_finish(0)

</stderr_txt>
]]>