𝕏

Task 55456045

Name HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_738_1
Workunit 26333957
Created 30 Jun 2024, 15:50:49 UTC
Sent 30 Jun 2024, 15:51:26 UTC
Report deadline 4 Jul 2024, 1:27:26 UTC
Received 30 Jun 2024, 20:48:48 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 221891
Run time 2 hours 25 min 17 sec
CPU time 2 hours 7 min 35 sec
Validate state Valid
Credit 59.08
Device peak FLOPS 5.49 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.11 MB
Peak swap size 4.26 GB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_738_1_r1481716318_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_738_1_r1481716318_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14544505, states[0] = 11.107514, states[40]= 0.004896
Saving checkpoint... 
Iteration: 29015005, states[0] = 20.413403, states[40]= 0.017030
Saving checkpoint... 
Iteration: 43524638, states[0] = 18.566516, states[40]= 0.006599
Saving checkpoint... 
Iteration: 58072942, states[0] = -1.507469, states[40]= 0.004038
Saving checkpoint... 
Iteration: 72354264, states[0] = -95.031421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86864938, states[0] = -95.032142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101337190, states[0] = -95.016849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115944911, states[0] = -95.050865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130527139, states[0] = 18.154831, states[40]= 0.006094
Saving checkpoint... 
Iteration: 144926882, states[0] = -95.045376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158463955, states[0] = -95.052084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171994238, states[0] = -95.056045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185296473, states[0] = -94.986254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197561081, states[0] = 5.258992, states[40]= 0.004677
Saving checkpoint... 
Iteration: 209119981, states[0] = -44.798143, states[40]= 0.000060
Saving checkpoint... 
Iteration: 220236955, states[0] = -94.921648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232321711, states[0] = -95.003483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244948514, states[0] = -95.048570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257612060, states[0] = -36.611176, states[40]= 0.000200
Saving checkpoint... 
Iteration: 270249353, states[0] = -94.938319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283018608, states[0] = 20.160175, states[40]= 0.010194
Saving checkpoint... 
Iteration: 294974477, states[0] = -95.052772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306803209, states[0] = -94.990911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319350414, states[0] = -95.018678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331715173, states[0] = -94.886268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344972861, states[0] = -95.052485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357885597, states[0] = -95.032540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370597250, states[0] = -21.885935, states[40]= 0.000833
Saving checkpoint... 
Iteration: 382873008, states[0] = -95.028067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395991181, states[0] = -95.054938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409299156, states[0] = -94.987782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423269293, states[0] = -94.961095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437297214, states[0] = -94.986260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449625018, states[0] = -50.211979, states[40]= 0.000026
Saving checkpoint... 
Iteration: 462139261, states[0] = -66.890507, states[40]= 0.000002
Saving checkpoint... 
Iteration: 475990148, states[0] = -95.054747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490333940, states[0] = -95.010255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504573822, states[0] = -1.518122, states[40]= 0.004026
Saving checkpoint... 
Iteration: 518741859, states[0] = -94.928191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531422442, states[0] = -95.042803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544506824, states[0] = 23.362253, states[40]= 0.111582
Saving checkpoint... 
Iteration: 557298682, states[0] = -94.987306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570194204, states[0] = -94.844834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583119647, states[0] = -44.431064, states[40]= 0.000064
Saving checkpoint... 
Iteration: 596322612, states[0] = -95.003662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609806285, states[0] = -94.992898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623090905, states[0] = -15.622378, states[40]= 0.001388
Saving checkpoint... 
Iteration: 636061490, states[0] = 5.074949, states[40]= 0.004668
Saving checkpoint... 
Iteration: 649966124, states[0] = -95.051220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664282800, states[0] = -94.973981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678452522, states[0] = -95.048909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692859254, states[0] = -95.022326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706447268, states[0] = -95.047923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719551676, states[0] = 9.352539, states[40]= 0.004808
Saving checkpoint... 
Iteration: 732364656, states[0] = -95.024544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745029657, states[0] = 17.440329, states[40]= 0.005729
Saving checkpoint... 
Iteration: 757819615, states[0] = -95.001693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770195913, states[0] = -94.848310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783611727, states[0] = -36.272242, states[40]= 0.000209
Saving checkpoint... 
Iteration: 797079619, states[0] = -5.542699, states[40]= 0.003291
Saving checkpoint... 
Iteration: 809502180, states[0] = 41.005010, states[40]= 0.118459
Saving checkpoint... 
Iteration: 822575325, states[0] = -2.485925, states[40]= 0.003871
Saving checkpoint... 
Iteration: 836012033, states[0] = 21.179933, states[40]= 0.031656


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_738.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_738_1_r1481716318_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_738_1_r1481716318_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 93.363726
     * GNaL_b in INaL: 0.004556
     * Gto_b in Ito: 0.090859
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.034075
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.170149
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.256397
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 836012033
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 21.179933 (After loading)
 - states[40]: 0.031656 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 852750339, states[0] = -94.939093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867582532, states[0] = -7.886316, states[40]= 0.002794
Saving checkpoint... 
Iteration: 882657175, states[0] = -92.904878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897450500, states[0] = -95.048378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912654553, states[0] = -90.857381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928701440, states[0] = -94.859610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945641079, states[0] = -69.388193, states[40]= 0.000001
Saving checkpoint... 
Iteration: 962705164, states[0] = -94.867000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979917734, states[0] = -95.041326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997350305, states[0] = -95.018108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014804777, states[0] = -94.991508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032300383, states[0] = -94.988244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050238464, states[0] = -94.923041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067723845, states[0] = -94.900615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085291874, states[0] = -94.981487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102877763, states[0] = -95.029266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121017600, states[0] = 20.336538, states[40]= 0.011509
Saving checkpoint... 
Iteration: 1138422037, states[0] = -95.042249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156046992, states[0] = 11.237424, states[40]= 0.004863
Saving checkpoint... 
Iteration: 1173684212, states[0] = -94.822155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191299340, states[0] = -94.987330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208998245, states[0] = -95.055176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226712165, states[0] = -94.880115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244412866, states[0] = -95.039895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262117146, states[0] = -41.808351, states[40]= 0.000095
Saving checkpoint... 
Iteration: 1279796461, states[0] = -94.985031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297509474, states[0] = 21.762554, states[40]= 0.058553
Saving checkpoint... 
Iteration: 1315119598, states[0] = -44.378638, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1332867449, states[0] = -95.025208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350521403, states[0] = 19.606889, states[40]= 0.007935
Saving checkpoint... 
Iteration: 1368216894, states[0] = -94.888533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385888293, states[0] = -95.032648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403528403, states[0] = 17.814880, states[40]= 0.005895
Saving checkpoint... 
Iteration: 1421219323, states[0] = -94.892726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438899840, states[0] = -95.036166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456527426, states[0] = 18.096394, states[40]= 0.006048
Saving checkpoint... 
Iteration: 1474116364, states[0] = -40.997796, states[40]= 0.000107
Saving checkpoint... 
Iteration: 1491366653, states[0] = -95.024773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506203174, states[0] = -95.168804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521387144, states[0] = -27.229514, states[40]= 0.000567
Saving checkpoint... 
Iteration: 1537806666, states[0] = 24.736285, states[40]= 0.107482
Saving checkpoint... 
Iteration: 1553516714, states[0] = -64.559838, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1569008534, states[0] = 23.053476, states[40]= 0.072423
Saving checkpoint... 
Iteration: 1584206302, states[0] = -95.218430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599566017, states[0] = -95.295135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615608354, states[0] = -54.380462, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1631030526, states[0] = -95.258590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646803186, states[0] = -48.025443, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1663136269, states[0] = -95.266507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678569878, states[0] = -9.606211, states[40]= 0.002734
Saving checkpoint... 
Iteration: 1693329830, states[0] = -88.223785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708190554, states[0] = -95.316938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723194657, states[0] = -95.319691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737309726, states[0] = 22.411553, states[40]= 0.055189
Saving checkpoint... 
Iteration: 1750542735, states[0] = 9.699695, states[40]= 0.005692
Saving checkpoint... 
Iteration: 1765656664, states[0] = -95.109681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780652313, states[0] = -95.093365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1795310381, states[0] = -57.074095, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1810311381, states[0] = -95.041473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825411045, states[0] = -95.070469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840993462, states[0] = -95.074115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856071133, states[0] = -0.285361, states[40]= 0.004209
Saving checkpoint... 
Iteration: 1871082552, states[0] = -8.288330, states[40]= 0.002713
Saving checkpoint... 
Iteration: 1886754045, states[0] = -94.948056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902616743, states[0] = -41.604133, states[40]= 0.000098
Saving checkpoint... 
Iteration: 1917883083, states[0] = -95.032492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932086821, states[0] = -11.777093, states[40]= 0.002001
Saving checkpoint... 
Iteration: 1947484037, states[0] = -95.053631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962740219, states[0] = -94.925312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977868127, states[0] = -95.025270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992257119, states[0] = -94.946637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007198596, states[0] = -94.853055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021846425, states[0] = -95.015524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037046390, states[0] = 11.473239, states[40]= 0.004872
Saving checkpoint... 
Iteration: 2051229351, states[0] = -94.908672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064166848, states[0] = -94.697499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078665979, states[0] = -94.667683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093900779, states[0] = -95.035889, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.930525
 - CaMKt in component CaMK (millimolar): 0.007119
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.594707
 - nass in component intracellular_ions (millimolar): 6.594768
 - ki in component intracellular_ions (millimolar): 145.378247
 - kss in component intracellular_ions (millimolar): 145.378227
 - cansr in component intracellular_ions (millimolar): 1.327244
 - cajsr in component intracellular_ions (millimolar): 1.289631
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003608
 - hf in component INa (dimensionless): 0.880497
 - hs in component INa (dimensionless): 0.880493
 - j in component INa (dimensionless): 0.880464
 - hsp in component INa (dimensionless): 0.726767
 - jp in component INa (dimensionless): 0.880445
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712202
 - hLp in component INaL (dimensionless): 0.457572
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.628338
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.705188
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.941730
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999906
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001662
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.306894
 - xs1 in component IKs (dimensionless): 0.229134
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997330
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:36:27 (1951): called boinc_finish(0)

</stderr_txt>
]]>


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