𝕏

Task 55456043

Name HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_937_1
Workunit 26333956
Created 30 Jun 2024, 15:50:49 UTC
Sent 30 Jun 2024, 15:51:26 UTC
Report deadline 4 Jul 2024, 1:27:26 UTC
Received 30 Jun 2024, 21:26:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 221891
Run time 2 hours 23 min 39 sec
CPU time 2 hours 8 min 2 sec
Validate state Valid
Credit 58.28
Device peak FLOPS 5.49 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.13 MB
Peak swap size 4.26 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_937.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_937_1_r28217707_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_937_1_r28217707_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.235490
     * GNaL_b in INaL: 0.005004
     * Gto_b in Ito: 0.095238
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031613
     * GKs_b in IKs: 0.002097
     * GK1_b in IK1: 0.179032
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 67.845819
     * GKb_b in IKb: 0.003842
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020489
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12693890, states[0] = -94.897742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25476824, states[0] = -95.075166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38262732, states[0] = -94.963823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51095113, states[0] = -15.423590, states[40]= 0.001407
Saving checkpoint... 
Iteration: 63127014, states[0] = -45.139017, states[40]= 0.000064
Saving checkpoint... 
Iteration: 75004922, states[0] = 25.917789, states[40]= 0.169473
Saving checkpoint... 
Iteration: 87647416, states[0] = -67.597291, states[40]= 0.000002
Saving checkpoint... 
Iteration: 100132291, states[0] = -50.072521, states[40]= 0.000029
Saving checkpoint... 
Iteration: 113370681, states[0] = -95.018662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126461185, states[0] = -95.041774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139262817, states[0] = -94.943285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151610274, states[0] = -28.578432, states[40]= 0.000559
Saving checkpoint... 
Iteration: 164829415, states[0] = -94.997242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178288486, states[0] = -94.967959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192418410, states[0] = -95.031616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206403188, states[0] = -95.027449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218694711, states[0] = -94.833041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231375525, states[0] = -95.018285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245274802, states[0] = -94.954899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259685601, states[0] = -94.811864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274027905, states[0] = 18.579627, states[40]= 0.005608
Saving checkpoint... 
Iteration: 288161254, states[0] = -89.826082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300862068, states[0] = -95.012829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313969053, states[0] = -95.041411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326888128, states[0] = -95.022561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339771991, states[0] = -94.951934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352841000, states[0] = -95.002926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366054762, states[0] = 9.512805, states[40]= 0.004703
Saving checkpoint... 
Iteration: 379526748, states[0] = 18.869560, states[40]= 0.005783
Saving checkpoint... 
Iteration: 392817091, states[0] = -94.988999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405921872, states[0] = -95.032070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419883282, states[0] = -95.020838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434258206, states[0] = -94.936676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448518059, states[0] = 20.530759, states[40]= 0.010184
Saving checkpoint... 
Iteration: 462888236, states[0] = -95.022476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476575669, states[0] = -0.036123, states[40]= 0.004184
Saving checkpoint... 
Iteration: 489720444, states[0] = -94.882304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502636617, states[0] = -54.399334, states[40]= 0.000014
Saving checkpoint... 
Iteration: 515344770, states[0] = -95.004697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528203931, states[0] = -94.851632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540652579, states[0] = -74.808718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554095586, states[0] = -15.031359, states[40]= 0.001455
Saving checkpoint... 
Iteration: 567661232, states[0] = -89.795718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580131612, states[0] = -49.109132, states[40]= 0.000034
Saving checkpoint... 
Iteration: 593264095, states[0] = -94.943286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606702393, states[0] = -94.848493, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_937.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_937_1_r28217707_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630175043487644_ORdGradInc_k_25-Pueyo_APDR-conf_937_1_r28217707_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.235490
     * GNaL_b in INaL: 0.005004
     * Gto_b in Ito: 0.095238
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031613
     * GKs_b in IKs: 0.002097
     * GK1_b in IK1: 0.179032
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 67.845819
     * GKb_b in IKb: 0.003842
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020489
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 606702393
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.848493 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 623457374, states[0] = -95.039211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638342405, states[0] = -95.003401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653528038, states[0] = 18.545807, states[40]= 0.005590
Saving checkpoint... 
Iteration: 668244841, states[0] = -94.919564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683468438, states[0] = -95.040994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699551594, states[0] = 10.728318, states[40]= 0.004709
Saving checkpoint... 
Iteration: 716470063, states[0] = -95.041219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733498430, states[0] = -95.045069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750772617, states[0] = -94.952219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768176470, states[0] = -94.758044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785730129, states[0] = -94.897989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803274464, states[0] = -94.954038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821161441, states[0] = -90.058340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838621851, states[0] = -39.356508, states[40]= 0.000151
Saving checkpoint... 
Iteration: 856206843, states[0] = -94.857067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873870684, states[0] = -95.015825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892022008, states[0] = 19.897741, states[40]= 0.007104
Saving checkpoint... 
Iteration: 909413416, states[0] = -95.029513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927091165, states[0] = -11.080130, states[40]= 0.002103
Saving checkpoint... 
Iteration: 944712162, states[0] = -94.867091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962383085, states[0] = -95.020308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980126318, states[0] = -43.722971, states[40]= 0.000079
Saving checkpoint... 
Iteration: 997844717, states[0] = -95.004259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015616057, states[0] = -33.884398, states[40]= 0.000316
Saving checkpoint... 
Iteration: 1033407596, states[0] = -95.027843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051126348, states[0] = -43.752787, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1068874081, states[0] = -95.016961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086542161, states[0] = 14.155724, states[40]= 0.004779
Saving checkpoint... 
Iteration: 1104313321, states[0] = -94.985889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122055919, states[0] = 9.059419, states[40]= 0.004699
Saving checkpoint... 
Iteration: 1139746473, states[0] = -94.921352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157417416, states[0] = -95.030329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175167983, states[0] = -94.146800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192882712, states[0] = -95.019982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210605119, states[0] = -23.794656, states[40]= 0.000782
Saving checkpoint... 
Iteration: 1228251566, states[0] = -94.927884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245932494, states[0] = -95.033803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263228102, states[0] = -94.894366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278162007, states[0] = -90.720721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293535106, states[0] = 16.508623, states[40]= 0.005001
Saving checkpoint... 
Iteration: 1310076021, states[0] = -0.234224, states[40]= 0.004159
Saving checkpoint... 
Iteration: 1325939306, states[0] = -95.035183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341581593, states[0] = -3.664677, states[40]= 0.003618
Saving checkpoint... 
Iteration: 1356912345, states[0] = -95.028850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372476786, states[0] = -95.041671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388720248, states[0] = -94.881195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404376280, states[0] = -95.017496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420336180, states[0] = -94.999466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436810116, states[0] = -94.983403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452595889, states[0] = -15.307348, states[40]= 0.001418
Saving checkpoint... 
Iteration: 1467515404, states[0] = 20.837672, states[40]= 0.015204
Saving checkpoint... 
Iteration: 1482661057, states[0] = -89.565133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497765994, states[0] = -94.944602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511863046, states[0] = -95.056905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525252109, states[0] = 6.665917, states[40]= 0.005336
Saving checkpoint... 
Iteration: 1540426518, states[0] = -95.205334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555450781, states[0] = -95.241773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1569989790, states[0] = -26.398951, states[40]= 0.000651
Saving checkpoint... 
Iteration: 1585270728, states[0] = -6.666531, states[40]= 0.003417
Saving checkpoint... 
Iteration: 1600423073, states[0] = -95.215839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616003064, states[0] = -95.184388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631140675, states[0] = 11.880578, states[40]= 0.005676
Saving checkpoint... 
Iteration: 1646251082, states[0] = -95.014357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661991560, states[0] = -95.287442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677940167, states[0] = 12.107727, states[40]= 0.005695
Saving checkpoint... 
Iteration: 1693251004, states[0] = 6.649402, states[40]= 0.005359
Saving checkpoint... 
Iteration: 1707540631, states[0] = -95.241331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723019291, states[0] = -60.493849, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1738316819, states[0] = -57.351229, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1753429713, states[0] = -95.227545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767689132, states[0] = -26.097140, states[40]= 0.000666
Saving checkpoint... 
Iteration: 1782831175, states[0] = -95.229470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797532546, states[0] = -95.231253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812830496, states[0] = -95.034323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826918493, states[0] = -95.057089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839907945, states[0] = -95.045882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1854535879, states[0] = 16.079748, states[40]= 0.004954
Saving checkpoint... 
Iteration: 1869808126, states[0] = -94.989348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885889973, states[0] = -95.026567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900263218, states[0] = -94.944311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914961447, states[0] = -95.040768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929305292, states[0] = -94.980803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943743138, states[0] = -94.916960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957599290, states[0] = -18.468407, states[40]= 0.001087
Saving checkpoint... 
Iteration: 1971457827, states[0] = -95.038447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985840244, states[0] = -95.001312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001175277, states[0] = -94.737047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015975061, states[0] = -95.040892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030712246, states[0] = -94.866300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045457228, states[0] = -95.037934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060088864, states[0] = -9.126152, states[40]= 0.002495
Saving checkpoint... 
Iteration: 2074688557, states[0] = -94.817614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089306045, states[0] = -94.979874, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.919891
 - CaMKt in component CaMK (millimolar): 0.007516
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.685863
 - nass in component intracellular_ions (millimolar): 6.685925
 - ki in component intracellular_ions (millimolar): 145.282017
 - kss in component intracellular_ions (millimolar): 145.281998
 - cansr in component intracellular_ions (millimolar): 1.346222
 - cajsr in component intracellular_ions (millimolar): 1.307619
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003612
 - hf in component INa (dimensionless): 0.880313
 - hs in component INa (dimensionless): 0.880309
 - j in component INa (dimensionless): 0.880280
 - hsp in component INa (dimensionless): 0.726419
 - jp in component INa (dimensionless): 0.880260
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710169
 - hLp in component INaL (dimensionless): 0.451939
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620293
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695598
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937086
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001728
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.313043
 - xs1 in component IKs (dimensionless): 0.240872
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:52:11 (1956): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge