𝕏

Task 55455900

Name HuVeMOp_20240630174541330981_ORdGradInc_k_25-Pueyo_APDR-conf_332_1
Workunit 26333886
Created 30 Jun 2024, 15:45:47 UTC
Sent 30 Jun 2024, 15:49:22 UTC
Report deadline 4 Jul 2024, 1:25:22 UTC
Received 1 Jul 2024, 15:36:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241688
Run time 2 hours 13 min 7 sec
CPU time 2 hours 9 min 55 sec
Validate state Valid
Credit 61.08
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.93 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630174541330981_ORdGradInc_k_25-Pueyo_APDR-conf_332.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630174541330981_ORdGradInc_k_25-Pueyo_APDR-conf_332_1_r1523312887_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630174541330981_ORdGradInc_k_25-Pueyo_APDR-conf_332_1_r1523312887_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 112.238903
     * GNaL_b in INaL: 0.005054
     * Gto_b in Ito: 0.077176
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030016
     * GKs_b in IKs: 0.001942
     * GK1_b in IK1: 0.176435
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 66.052043
     * GKb_b in IKb: 0.003836
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019665
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16958565, states[0] = -95.130053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33683408, states[0] = -94.893808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50497660, states[0] = -95.104837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67341641, states[0] = -95.058818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84360230, states[0] = -95.063369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101355459, states[0] = -95.059129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118507786, states[0] = 25.487452, states[40]= 0.088652
Saving checkpoint... 
Iteration: 136018589, states[0] = 21.795957, states[40]= 0.011906
Saving checkpoint... 
Iteration: 153128427, states[0] = -47.998991, states[40]= 0.000039
Saving checkpoint... 
Iteration: 170017410, states[0] = 22.077801, states[40]= 0.013678
Saving checkpoint... 
Iteration: 187346715, states[0] = -95.051919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204816636, states[0] = -95.035676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222406639, states[0] = -95.072925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241680265, states[0] = -94.855919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260939482, states[0] = -95.080354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279696474, states[0] = -94.893154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298097276, states[0] = -17.977367, states[40]= 0.001150
Saving checkpoint... 
Iteration: 316945032, states[0] = -95.081354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334403359, states[0] = -95.071865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352572530, states[0] = 0.981069, states[40]= 0.004467
Saving checkpoint... 
Iteration: 371860253, states[0] = -95.057376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389899842, states[0] = -95.070851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406405059, states[0] = -95.072279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423141534, states[0] = -62.459408, states[40]= 0.000003
Saving checkpoint... 
Iteration: 440431582, states[0] = -95.078599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459724861, states[0] = -94.942722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478081811, states[0] = -4.754151, states[40]= 0.003508
Saving checkpoint... 
Iteration: 495142661, states[0] = -63.849111, states[40]= 0.000003
Saving checkpoint... 
Iteration: 511363039, states[0] = -95.058411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527702953, states[0] = -94.905349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544307994, states[0] = -95.029721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560771502, states[0] = -95.000197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577319474, states[0] = -95.036991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594079038, states[0] = -2.870279, states[40]= 0.003877
Saving checkpoint... 
Iteration: 610641737, states[0] = -62.706613, states[40]= 0.000003
Saving checkpoint... 
Iteration: 627083180, states[0] = -5.747390, states[40]= 0.003298
Saving checkpoint... 
Iteration: 643755403, states[0] = -94.983261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660271103, states[0] = -94.999752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676201338, states[0] = -94.902231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692753383, states[0] = -94.980912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709191297, states[0] = -94.882560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725415646, states[0] = -95.074806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741723557, states[0] = -94.940532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757889588, states[0] = -95.067598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773736331, states[0] = -94.959267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790053582, states[0] = 9.739797, states[40]= 0.005088
Saving checkpoint... 
Iteration: 806273197, states[0] = -95.001674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822379112, states[0] = -95.064149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838598791, states[0] = -19.393147, states[40]= 0.001032
Saving checkpoint... 
Iteration: 855040613, states[0] = 14.865162, states[40]= 0.005481
Saving checkpoint... 
Iteration: 871620779, states[0] = -40.177425, states[40]= 0.000128
Saving checkpoint... 
Iteration: 888192025, states[0] = -94.883932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904822605, states[0] = -95.038649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921555306, states[0] = 9.023967, states[40]= 0.005055
Saving checkpoint... 
Iteration: 937975702, states[0] = -95.085982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954608668, states[0] = -28.631781, states[40]= 0.000544
Saving checkpoint... 
Iteration: 971161391, states[0] = -92.280783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988121604, states[0] = -40.989859, states[40]= 0.000113
Saving checkpoint... 
Iteration: 1004812516, states[0] = -95.032418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021379084, states[0] = -95.064021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037991120, states[0] = -95.087953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054686431, states[0] = -94.872061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071198217, states[0] = -94.896042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087914839, states[0] = -95.074394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104640092, states[0] = -60.732766, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1121438111, states[0] = -95.079536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138361185, states[0] = -95.057299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155099573, states[0] = -20.124659, states[40]= 0.000980
Saving checkpoint... 
Iteration: 1171669601, states[0] = -94.663951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188248925, states[0] = -94.975326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204824077, states[0] = -95.039322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221517296, states[0] = 22.109355, states[40]= 0.013882
Saving checkpoint... 
Iteration: 1238153746, states[0] = -80.992678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254827983, states[0] = -95.041493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271428225, states[0] = -95.077388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288249285, states[0] = -94.975703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304978992, states[0] = -95.086224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321779793, states[0] = -95.007427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338900117, states[0] = -95.070367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355893301, states[0] = -95.068377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372655820, states[0] = -84.845165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389618651, states[0] = -38.103506, states[40]= 0.000172
Saving checkpoint... 
Iteration: 1406304918, states[0] = -95.027115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422983434, states[0] = -95.086750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439671043, states[0] = -94.734072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456279707, states[0] = -95.007271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473104484, states[0] = -24.715274, states[40]= 0.000735
Saving checkpoint... 
Iteration: 1489684141, states[0] = -94.866450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506281611, states[0] = -95.282965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522618929, states[0] = -58.124069, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1539081444, states[0] = -17.096959, states[40]= 0.001367
Saving checkpoint... 
Iteration: 1555375453, states[0] = -95.171519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1571890679, states[0] = -95.207951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588524674, states[0] = 19.421038, states[40]= 0.008874
Saving checkpoint... 
Iteration: 1605337470, states[0] = 13.720944, states[40]= 0.006518
Saving checkpoint... 
Iteration: 1621860626, states[0] = 0.818492, states[40]= 0.005003
Saving checkpoint... 
Iteration: 1638640839, states[0] = 12.029864, states[40]= 0.006247
Saving checkpoint... 
Iteration: 1655377775, states[0] = -95.322928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672071555, states[0] = -95.173517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688554169, states[0] = -95.116887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705113948, states[0] = -95.254350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721739824, states[0] = 12.524427, states[40]= 0.006322
Saving checkpoint... 
Iteration: 1738156068, states[0] = -95.304990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1754396237, states[0] = -95.335917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770555404, states[0] = -95.304358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786567261, states[0] = -4.136948, states[40]= 0.004079
Saving checkpoint... 
Iteration: 1802045812, states[0] = 11.854129, states[40]= 0.005320
Saving checkpoint... 
Iteration: 1818101848, states[0] = -24.733375, states[40]= 0.000737
Saving checkpoint... 
Iteration: 1834383583, states[0] = -95.086454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850932986, states[0] = -95.091401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867202685, states[0] = -94.912677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883750923, states[0] = -94.982627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900166492, states[0] = -94.388104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916634966, states[0] = -55.121982, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1933504650, states[0] = 31.135238, states[40]= 0.146139
Saving checkpoint... 
Iteration: 1949911395, states[0] = -95.073772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966556995, states[0] = 8.300832, states[40]= 0.005023
Saving checkpoint... 
Iteration: 1982886121, states[0] = -95.066046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984237797, states[0] = -94.960815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000689446, states[0] = -94.878121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017093434, states[0] = -14.414908, states[40]= 0.001577
Saving checkpoint... 
Iteration: 2033789114, states[0] = -95.014935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049919478, states[0] = -95.074942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066032073, states[0] = 17.936967, states[40]= 0.006179
Saving checkpoint... 
Iteration: 2082350557, states[0] = -95.052200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098860245, states[0] = -95.056313, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.964209
 - CaMKt in component CaMK (millimolar): 0.006911
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.678073
 - nass in component intracellular_ions (millimolar): 6.678132
 - ki in component intracellular_ions (millimolar): 145.299594
 - kss in component intracellular_ions (millimolar): 145.299575
 - cansr in component intracellular_ions (millimolar): 1.313956
 - cajsr in component intracellular_ions (millimolar): 1.276310
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003596
 - hf in component INa (dimensionless): 0.881079
 - hs in component INa (dimensionless): 0.881074
 - j in component INa (dimensionless): 0.881046
 - hsp in component INa (dimensionless): 0.727865
 - jp in component INa (dimensionless): 0.881028
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711869
 - hLp in component INaL (dimensionless): 0.454835
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.622717
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.697941
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935897
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001620
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.336648
 - xs1 in component IKs (dimensionless): 0.238735
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997321
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:35:43 (2292827): called boinc_finish(0)

</stderr_txt>
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