𝕏

Task 55454393

Name HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_740_0
Workunit 26333179
Created 30 Jun 2024, 14:50:48 UTC
Sent 30 Jun 2024, 15:43:45 UTC
Report deadline 4 Jul 2024, 1:19:45 UTC
Received 30 Jun 2024, 18:13:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 29 min 36 sec
CPU time 2 hours 27 min 11 sec
Validate state Valid
Credit 59.35
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_740.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_740_0_r440137139_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_740_0_r440137139_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.842984
     * GNaL_b in INaL: 0.005206
     * Gto_b in Ito: 0.087831
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030352
     * GKs_b in IKs: 0.002094
     * GK1_b in IK1: 0.169383
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 72.862458
     * GKb_b in IKb: 0.003785
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021749
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14691823, states[0] = -94.938176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29444182, states[0] = -95.105956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44591669, states[0] = -12.237008, states[40]= 0.001909
Saving checkpoint... 
Iteration: 59877510, states[0] = -95.054933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74592331, states[0] = -11.823210, states[40]= 0.001976
Saving checkpoint... 
Iteration: 89738813, states[0] = -94.932825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105000244, states[0] = -65.077151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120353917, states[0] = -95.028397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135027206, states[0] = 19.386060, states[40]= 0.006324
Saving checkpoint... 
Iteration: 149557302, states[0] = 8.925964, states[40]= 0.004836
Saving checkpoint... 
Iteration: 164289749, states[0] = -94.984195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179021629, states[0] = 20.710121, states[40]= 0.008198
Saving checkpoint... 
Iteration: 193480509, states[0] = -95.060408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208224964, states[0] = -94.902874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223221633, states[0] = -94.897062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238144477, states[0] = -61.826399, states[40]= 0.000004
Saving checkpoint... 
Iteration: 252801059, states[0] = -94.992728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267333862, states[0] = -95.014724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282144110, states[0] = -61.394709, states[40]= 0.000004
Saving checkpoint... 
Iteration: 296593305, states[0] = -11.997182, states[40]= 0.001937
Saving checkpoint... 
Iteration: 311311161, states[0] = -95.000191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326043335, states[0] = 14.247015, states[40]= 0.005026
Saving checkpoint... 
Iteration: 340412537, states[0] = -95.046213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355086516, states[0] = -6.415591, states[40]= 0.003081
Saving checkpoint... 
Iteration: 369599875, states[0] = -17.951756, states[40]= 0.001133
Saving checkpoint... 
Iteration: 384423088, states[0] = -95.048912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399208934, states[0] = -94.873389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414136895, states[0] = -53.462930, states[40]= 0.000016
Saving checkpoint... 
Iteration: 429031784, states[0] = 18.114549, states[40]= 0.005681
Saving checkpoint... 
Iteration: 443709814, states[0] = -94.875060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458381971, states[0] = -95.036524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473087722, states[0] = -7.339609, states[40]= 0.002883
Saving checkpoint... 
Iteration: 487676982, states[0] = -94.732694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502556557, states[0] = 9.251198, states[40]= 0.004843
Saving checkpoint... 
Iteration: 517631584, states[0] = -47.922058, states[40]= 0.000040
Saving checkpoint... 
Iteration: 532680543, states[0] = -94.790700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547765911, states[0] = -94.959304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562681097, states[0] = -94.795681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577196602, states[0] = -94.848168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591923617, states[0] = -95.048898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606622880, states[0] = -39.283801, states[40]= 0.000149
Saving checkpoint... 
Iteration: 621261723, states[0] = -94.954454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635717064, states[0] = -94.888493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650217231, states[0] = -94.888786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664397599, states[0] = -95.041630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678497524, states[0] = -95.061988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692593616, states[0] = -12.270181, states[40]= 0.001888
Saving checkpoint... 
Iteration: 706679378, states[0] = -94.777429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720767519, states[0] = -94.960974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735594653, states[0] = -13.192425, states[40]= 0.001732
Saving checkpoint... 
Iteration: 749594549, states[0] = -13.099411, states[40]= 0.001747
Saving checkpoint... 
Iteration: 763350954, states[0] = -95.023317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777178916, states[0] = -94.770918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791009379, states[0] = 22.902938, states[40]= 0.060989
Saving checkpoint... 
Iteration: 804789076, states[0] = -94.982273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819260107, states[0] = -94.952409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833863029, states[0] = -95.028784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847887405, states[0] = -95.038167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861492301, states[0] = -95.061200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875200502, states[0] = -94.856160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888806805, states[0] = -94.996614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902267962, states[0] = -94.961335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915880173, states[0] = -95.035553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929374259, states[0] = -95.033312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942830672, states[0] = -95.012370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956422941, states[0] = -95.048480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970500546, states[0] = 1.374593, states[40]= 0.000253
Saving checkpoint... 
Iteration: 985108864, states[0] = -26.214404, states[40]= 0.000670
Saving checkpoint... 
Iteration: 999500855, states[0] = 45.693837, states[40]= 0.018098
Saving checkpoint... 
Iteration: 1013096208, states[0] = -14.594122, states[40]= 0.001518
Saving checkpoint... 
Iteration: 1026509760, states[0] = 22.773571, states[40]= 0.055633
Saving checkpoint... 
Iteration: 1040097123, states[0] = -15.426888, states[40]= 0.001406
Saving checkpoint... 
Iteration: 1053653691, states[0] = -74.105781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067087983, states[0] = -7.543527, states[40]= 0.002839
Saving checkpoint... 
Iteration: 1080866232, states[0] = -95.029974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094939434, states[0] = -95.052164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109374167, states[0] = -95.033152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122985160, states[0] = -95.060060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136699028, states[0] = -94.852912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150245479, states[0] = -94.933404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163789689, states[0] = -94.982567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177243673, states[0] = -94.930867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190966877, states[0] = -95.057243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204338742, states[0] = -95.016750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218157038, states[0] = -79.730704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231734863, states[0] = -94.917874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245683332, states[0] = -94.809999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259937641, states[0] = -95.051667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273933426, states[0] = -95.050730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287370709, states[0] = -95.031665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301810644, states[0] = -94.999126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316948639, states[0] = -95.053884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331852902, states[0] = -95.023858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347001816, states[0] = 45.550919, states[40]= 0.085241
Saving checkpoint... 
Iteration: 1362400361, states[0] = -95.042000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377924707, states[0] = -95.048622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393254310, states[0] = -94.944903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408668761, states[0] = -93.762002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423718133, states[0] = -94.889876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438730006, states[0] = -94.910091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453618939, states[0] = -35.546632, states[40]= 0.000250
Saving checkpoint... 
Iteration: 1468333273, states[0] = -95.013516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483297660, states[0] = -94.989095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498470421, states[0] = -95.057606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513267346, states[0] = -1.595620, states[40]= 0.004450
Saving checkpoint... 
Iteration: 1528157017, states[0] = -95.263757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542993532, states[0] = -28.449657, states[40]= 0.000545
Saving checkpoint... 
Iteration: 1557706923, states[0] = -43.290514, states[40]= 0.000084
Saving checkpoint... 
Iteration: 1572438951, states[0] = -89.024827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1587279922, states[0] = -95.308146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601985357, states[0] = -95.313934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617037526, states[0] = 13.920117, states[40]= 0.006137
Saving checkpoint... 
Iteration: 1632037052, states[0] = 14.128733, states[40]= 0.006171
Saving checkpoint... 
Iteration: 1646966266, states[0] = -95.299983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661741339, states[0] = 12.108108, states[40]= 0.005908
Saving checkpoint... 
Iteration: 1676494671, states[0] = -30.642061, states[40]= 0.000440
Saving checkpoint... 
Iteration: 1691272754, states[0] = -95.150004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705970089, states[0] = -95.143094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721145383, states[0] = 10.116399, states[40]= 0.005723
Saving checkpoint... 
Iteration: 1736190879, states[0] = -26.609655, states[40]= 0.000637
Saving checkpoint... 
Iteration: 1751150508, states[0] = 7.467473, states[40]= 0.005524
Saving checkpoint... 
Iteration: 1766089324, states[0] = -95.319269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1781186687, states[0] = -22.132396, states[40]= 0.000891
Saving checkpoint... 
Iteration: 1795906487, states[0] = -43.495189, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1810683410, states[0] = -94.854748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825688141, states[0] = -94.857857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840639429, states[0] = -57.804094, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1855385235, states[0] = -95.049308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870343026, states[0] = -95.026625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885039747, states[0] = 15.438089, states[40]= 0.005145
Saving checkpoint... 
Iteration: 1899639756, states[0] = -56.810451, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1914708104, states[0] = -94.872875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929662230, states[0] = -88.670843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944500982, states[0] = 47.439585, states[40]= 0.027726
Saving checkpoint... 
Iteration: 1959284718, states[0] = -94.978048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1974198567, states[0] = -94.851680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989146244, states[0] = -63.931770, states[40]= 0.000003
Saving checkpoint... 
Iteration: 2004118600, states[0] = -35.238310, states[40]= 0.000261
Saving checkpoint... 
Iteration: 2018990433, states[0] = -95.060195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033711829, states[0] = -94.877811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048518082, states[0] = 21.363772, states[40]= 0.011392
Saving checkpoint... 
Iteration: 2063416620, states[0] = -95.046075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078176934, states[0] = -94.730242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092843019, states[0] = -95.018364, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.937136
 - CaMKt in component CaMK (millimolar): 0.007161
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.501332
 - nass in component intracellular_ions (millimolar): 6.501392
 - ki in component intracellular_ions (millimolar): 145.473464
 - kss in component intracellular_ions (millimolar): 145.473445
 - cansr in component intracellular_ions (millimolar): 1.322322
 - cajsr in component intracellular_ions (millimolar): 1.283921
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003606
 - hf in component INa (dimensionless): 0.880612
 - hs in component INa (dimensionless): 0.880607
 - j in component INa (dimensionless): 0.880577
 - hsp in component INa (dimensionless): 0.726981
 - jp in component INa (dimensionless): 0.880557
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710169
 - hLp in component INaL (dimensionless): 0.451071
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.618839
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.693466
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934637
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999882
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001642
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329771
 - xs1 in component IKs (dimensionless): 0.244118
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997328
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:13:29 (598317): called boinc_finish(0)

</stderr_txt>
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