𝕏

Task 55454335

Name HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_117_0
Workunit 26333150
Created 30 Jun 2024, 14:50:48 UTC
Sent 30 Jun 2024, 15:38:02 UTC
Report deadline 4 Jul 2024, 1:14:02 UTC
Received 2 Jul 2024, 9:57:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215413
Run time 1 hours 44 min 16 sec
CPU time 1 hours 40 min 21 sec
Validate state Valid
Credit 62.72
Device peak FLOPS 4.30 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.94 MB
Peak swap size 6.41 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_117.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_117_0_r736308658_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_117_0_r736308658_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 95.657743
     * GNaL_b in INaL: 0.005944
     * Gto_b in Ito: 0.093098
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030439
     * GKs_b in IKs: 0.002085
     * GK1_b in IK1: 0.165933
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 66.286257
     * GKb_b in IKb: 0.003767
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029403
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 22554859, states[0] = 10.142072, states[40]= 0.004742
Saving checkpoint... 
Iteration: 44880279, states[0] = -95.077163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67484588, states[0] = -95.092610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89554734, states[0] = 10.822608, states[40]= 0.004749
Saving checkpoint... 
Iteration: 111417004, states[0] = -95.071645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133459867, states[0] = -95.079822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155150428, states[0] = -64.514322, states[40]= 0.000003
Saving checkpoint... 
Iteration: 177653612, states[0] = -68.552478, states[40]= 0.000001
Saving checkpoint... 
Iteration: 199289792, states[0] = -95.002212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221214968, states[0] = -94.899287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243399411, states[0] = -95.063561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265635238, states[0] = -47.812230, states[40]= 0.000044


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_117.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_117_0_r736308658_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_117_0_r736308658_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 95.657743
     * GNaL_b in INaL: 0.005944
     * Gto_b in Ito: 0.093098
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030439
     * GKs_b in IKs: 0.002085
     * GK1_b in IK1: 0.165933
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 66.286257
     * GKb_b in IKb: 0.003767
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029403
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 265635238
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -47.812230 (After loading)
 - states[40]: 0.000044 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 286788786, states[0] = -95.000996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309687962, states[0] = -94.834059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331420441, states[0] = -95.069499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354574397, states[0] = 2.614031, states[40]= 0.004454
Saving checkpoint... 
Iteration: 377344516, states[0] = -95.040551, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_117.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_117_0_r736308658_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630165045718784_ORdGradInc_k_25-Pueyo_APDR-conf_117_0_r736308658_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 95.657743
     * GNaL_b in INaL: 0.005944
     * Gto_b in Ito: 0.093098
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030439
     * GKs_b in IKs: 0.002085
     * GK1_b in IK1: 0.165933
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 66.286257
     * GKb_b in IKb: 0.003767
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029403
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 377344516
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.040551 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 397186462, states[0] = -94.825569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417323702, states[0] = -95.028194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439795671, states[0] = -95.007025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462612085, states[0] = -26.038930, states[40]= 0.000715
Saving checkpoint... 
Iteration: 483644000, states[0] = -57.065936, states[40]= 0.000010
Saving checkpoint... 
Iteration: 506355906, states[0] = -95.046210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529155895, states[0] = -71.709114, states[40]= 0.000001
Saving checkpoint... 
Iteration: 552153316, states[0] = -68.110535, states[40]= 0.000001
Saving checkpoint... 
Iteration: 575369785, states[0] = -95.052380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598112114, states[0] = -26.064799, states[40]= 0.000713
Saving checkpoint... 
Iteration: 620954205, states[0] = -95.076842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643305343, states[0] = -95.014837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666072359, states[0] = 3.599235, states[40]= 0.004529
Saving checkpoint... 
Iteration: 689254841, states[0] = -94.962997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712340627, states[0] = -95.038164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735440710, states[0] = -95.074002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758831656, states[0] = -95.032927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781544759, states[0] = 14.499673, states[40]= 0.004793
Saving checkpoint... 
Iteration: 804686318, states[0] = -94.824287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827737446, states[0] = -94.937894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850796516, states[0] = -95.007424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874135745, states[0] = -48.329184, states[40]= 0.000041
Saving checkpoint... 
Iteration: 897200640, states[0] = -94.869359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920394503, states[0] = -95.061357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943389825, states[0] = -95.059748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966385533, states[0] = -95.058208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989383737, states[0] = -95.057534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012126803, states[0] = -39.487345, states[40]= 0.000156
Saving checkpoint... 
Iteration: 1035056932, states[0] = 10.094965, states[40]= 0.004743
Saving checkpoint... 
Iteration: 1057009210, states[0] = 22.469848, states[40]= 0.062684
Saving checkpoint... 
Iteration: 1079798650, states[0] = -95.009051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101606801, states[0] = -21.313167, states[40]= 0.000922
Saving checkpoint... 
Iteration: 1124230837, states[0] = -94.926966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146848212, states[0] = -95.041873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169233279, states[0] = -94.930960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191986664, states[0] = -95.081745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214195366, states[0] = -94.857104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235939048, states[0] = -95.073239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258020425, states[0] = 21.111435, states[40]= 0.008237
Saving checkpoint... 
Iteration: 1281004511, states[0] = 28.031324, states[40]= 0.173300
Saving checkpoint... 
Iteration: 1303642186, states[0] = -55.098669, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1326387492, states[0] = -95.058622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348690953, states[0] = -94.844906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371452461, states[0] = -95.075906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394175685, states[0] = -94.399813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416637576, states[0] = -50.222966, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1439088271, states[0] = -5.588525, states[40]= 0.003226
Saving checkpoint... 
Iteration: 1461962430, states[0] = -95.077685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484744212, states[0] = -94.947611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507346777, states[0] = -91.265004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529753030, states[0] = 7.536601, states[40]= 0.005411
Saving checkpoint... 
Iteration: 1551568177, states[0] = -95.313908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574108870, states[0] = 23.500434, states[40]= 0.067674
Saving checkpoint... 
Iteration: 1596631343, states[0] = 17.068815, states[40]= 0.006358
Saving checkpoint... 
Iteration: 1618875938, states[0] = -8.736732, states[40]= 0.002926
Saving checkpoint... 
Iteration: 1641522067, states[0] = -95.271203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663550343, states[0] = 8.372716, states[40]= 0.005481
Saving checkpoint... 
Iteration: 1685837276, states[0] = -82.009501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1707948761, states[0] = 9.164357, states[40]= 0.005522
Saving checkpoint... 
Iteration: 1729742367, states[0] = -95.300444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750688727, states[0] = -95.208368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772815206, states[0] = -50.451155, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1795124984, states[0] = -95.276408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817007872, states[0] = 22.790976, states[40]= 0.088872
Saving checkpoint... 
Iteration: 1839016379, states[0] = 21.432861, states[40]= 0.013132
Saving checkpoint... 
Iteration: 1861251106, states[0] = -94.968987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883987462, states[0] = -95.087337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906787274, states[0] = -95.001394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930077889, states[0] = 0.775421, states[40]= 0.004275
Saving checkpoint... 
Iteration: 1953312605, states[0] = -95.020050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975370626, states[0] = -95.051977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997408051, states[0] = -95.064886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019157465, states[0] = -74.097466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2041142651, states[0] = -55.604320, states[40]= 0.000012
Saving checkpoint... 
Iteration: 2062844101, states[0] = -95.038933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085451272, states[0] = -95.075041, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.958597
 - CaMKt in component CaMK (millimolar): 0.007531
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.669145
 - nass in component intracellular_ions (millimolar): 6.669207
 - ki in component intracellular_ions (millimolar): 145.300366
 - kss in component intracellular_ions (millimolar): 145.300346
 - cansr in component intracellular_ions (millimolar): 1.341335
 - cajsr in component intracellular_ions (millimolar): 1.302198
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003598
 - hf in component INa (dimensionless): 0.880982
 - hs in component INa (dimensionless): 0.880977
 - j in component INa (dimensionless): 0.880946
 - hsp in component INa (dimensionless): 0.727680
 - jp in component INa (dimensionless): 0.880926
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.709750
 - hLp in component INaL (dimensionless): 0.448848
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.614899
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.688838
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931704
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999872
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001708
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328559
 - xs1 in component IKs (dimensionless): 0.251174
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997322
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:56:19 (5272): called boinc_finish(0)

</stderr_txt>
]]>


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