𝕏

Task 55454200

Name HuVeMOp_20240630164544976038_ORdGradInc_k_25-Pueyo_APDR-conf_496_0
Workunit 26333086
Created 30 Jun 2024, 14:45:51 UTC
Sent 30 Jun 2024, 15:39:46 UTC
Report deadline 4 Jul 2024, 1:15:46 UTC
Received 1 Jul 2024, 8:10:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 5087
Run time 2 hours 3 min 53 sec
CPU time 2 hours 3 min 50 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 3.29 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 4.42 MB
Peak swap size 2.40 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.6.33</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630164544976038_ORdGradInc_k_25-Pueyo_APDR-conf_496.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630164544976038_ORdGradInc_k_25-Pueyo_APDR-conf_496_0_r1296142053_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630164544976038_ORdGradInc_k_25-Pueyo_APDR-conf_496_0_r1296142053_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 116.308203
     * GNaL_b in INaL: 0.006843
     * Gto_b in Ito: 0.085731
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032955
     * GKs_b in IKs: 0.002132
     * GK1_b in IK1: 0.148638
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 74.755530
     * GKb_b in IKb: 0.003844
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019184
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 18531908, states[0] = 17.400802, states[40]= 0.005932
Saving checkpoint... 
Iteration: 37072301, states[0] = 0.960565, states[40]= 0.004431
Saving checkpoint... 
Iteration: 55614714, states[0] = -34.738725, states[40]= 0.000272
Saving checkpoint... 
Iteration: 74154243, states[0] = -80.790567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92693874, states[0] = -94.792026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111235022, states[0] = -94.872441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129778128, states[0] = -94.929672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148319414, states[0] = -94.965562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166859635, states[0] = -94.989073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185397455, states[0] = -95.004353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203938149, states[0] = -95.015821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222476610, states[0] = -95.023322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241013303, states[0] = 22.676523, states[40]= 0.026389
Saving checkpoint... 
Iteration: 259554700, states[0] = 10.140266, states[40]= 0.004962
Saving checkpoint... 
Iteration: 278092561, states[0] = -12.100037, states[40]= 0.001939
Saving checkpoint... 
Iteration: 296631756, states[0] = -50.801143, states[40]= 0.000025
Saving checkpoint... 
Iteration: 315169049, states[0] = -94.002206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333707718, states[0] = -94.813834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352247618, states[0] = -94.886889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370785353, states[0] = -94.934038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389322917, states[0] = -94.966123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407862749, states[0] = -94.989414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426401999, states[0] = -95.005157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444940050, states[0] = -95.015782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463480376, states[0] = -95.023591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482021306, states[0] = 21.250122, states[40]= 0.008970
Saving checkpoint... 
Iteration: 500557696, states[0] = 8.913931, states[40]= 0.004923
Saving checkpoint... 
Iteration: 519095905, states[0] = -15.205679, states[40]= 0.001445
Saving checkpoint... 
Iteration: 537634090, states[0] = -53.389002, states[40]= 0.000016
Saving checkpoint... 
Iteration: 556172512, states[0] = -94.460064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574711656, states[0] = -94.822076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593249495, states[0] = -94.889534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611788359, states[0] = -94.936923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630323255, states[0] = -94.966211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648860610, states[0] = -94.988226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667400756, states[0] = -95.004593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685940580, states[0] = -95.015756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704479307, states[0] = -95.023271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723019977, states[0] = 21.520914, states[40]= 0.010008
Saving checkpoint... 
Iteration: 741560621, states[0] = 7.677719, states[40]= 0.004879
Saving checkpoint... 
Iteration: 760100208, states[0] = -19.299297, states[40]= 0.001022
Saving checkpoint... 
Iteration: 778638812, states[0] = -58.709767, states[40]= 0.000007
Saving checkpoint... 
Iteration: 797176702, states[0] = -94.659760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815714613, states[0] = -94.828066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834253831, states[0] = -94.895648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852794221, states[0] = -94.942435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871335516, states[0] = -94.974184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889872969, states[0] = -94.993794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908412469, states[0] = -95.008171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926950944, states[0] = -95.017897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945491390, states[0] = -95.024960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964030499, states[0] = 18.884220, states[40]= 0.006114
Saving checkpoint... 
Iteration: 982568571, states[0] = 4.062204, states[40]= 0.004685
Saving checkpoint... 
Iteration: 1001109166, states[0] = -27.852764, states[40]= 0.000575
Saving checkpoint... 
Iteration: 1019648091, states[0] = -70.022645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1038185143, states[0] = -94.754439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056725014, states[0] = -94.848341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075268147, states[0] = -94.914323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093807269, states[0] = -94.953755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112348066, states[0] = -94.981407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130887244, states[0] = -94.999468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149428188, states[0] = -95.012426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167964080, states[0] = -95.020348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186502681, states[0] = 40.657976, states[40]= 0.114611
Saving checkpoint... 
Iteration: 1205044504, states[0] = 14.095501, states[40]= 0.005144
Saving checkpoint... 
Iteration: 1223581209, states[0] = -3.048470, states[40]= 0.003792
Saving checkpoint... 
Iteration: 1242122761, states[0] = -41.184297, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1260660849, states[0] = -88.992595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279199983, states[0] = -94.796008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297738079, states[0] = -94.871236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316276112, states[0] = -94.923517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334814847, states[0] = -94.959614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353353754, states[0] = -94.984318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371892625, states[0] = -95.001320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390431617, states[0] = -95.013155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408972322, states[0] = -95.021674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427512406, states[0] = 22.843231, states[40]= 0.031778
Saving checkpoint... 
Iteration: 1446050942, states[0] = 11.634888, states[40]= 0.005012
Saving checkpoint... 
Iteration: 1464587632, states[0] = -7.817284, states[40]= 0.002811
Saving checkpoint... 
Iteration: 1483128813, states[0] = -47.576874, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1501662879, states[0] = -95.027813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520124785, states[0] = 19.850916, states[40]= 0.008614
Saving checkpoint... 
Iteration: 1538585506, states[0] = -95.152420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557050137, states[0] = 7.828500, states[40]= 0.005634
Saving checkpoint... 
Iteration: 1575513673, states[0] = -95.231226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593978253, states[0] = -13.871197, states[40]= 0.001855
Saving checkpoint... 
Iteration: 1612441221, states[0] = -95.280164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630904420, states[0] = -43.032162, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1649367929, states[0] = -95.312955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667832241, states[0] = -81.053845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686292769, states[0] = -95.335377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1704753660, states[0] = -95.026797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723215551, states[0] = 22.378472, states[40]= 0.019184
Saving checkpoint... 
Iteration: 1741676733, states[0] = -95.156033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760139950, states[0] = 12.851355, states[40]= 0.006157
Saving checkpoint... 
Iteration: 1778600513, states[0] = -95.213002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797063070, states[0] = -0.287295, states[40]= 0.004780
Saving checkpoint... 
Iteration: 1815517916, states[0] = 21.520602, states[40]= 0.012087
Saving checkpoint... 
Iteration: 1833971109, states[0] = -95.052536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852423588, states[0] = -95.028672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870877493, states[0] = -95.005333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889330267, states[0] = -94.976036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907783205, states[0] = -94.934203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926236621, states[0] = -94.870332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944692058, states[0] = -94.777507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963145315, states[0] = -66.475079, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1981600164, states[0] = -19.274301, states[40]= 0.001024
Saving checkpoint... 
Iteration: 2000054048, states[0] = 10.400893, states[40]= 0.004970
Saving checkpoint... 
Iteration: 2018507854, states[0] = 24.593770, states[40]= 0.089285
Saving checkpoint... 
Iteration: 2036963313, states[0] = -95.019686, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630164544976038_ORdGradInc_k_25-Pueyo_APDR-conf_496.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630164544976038_ORdGradInc_k_25-Pueyo_APDR-conf_496_0_r1296142053_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630164544976038_ORdGradInc_k_25-Pueyo_APDR-conf_496_0_r1296142053_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 116.308203
     * GNaL_b in INaL: 0.006843
     * Gto_b in Ito: 0.085731
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032955
     * GKs_b in IKs: 0.002132
     * GK1_b in IK1: 0.148638
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 74.755530
     * GKb_b in IKb: 0.003844
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019184
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 2036963313
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.019686 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading resultsTime...
Loading resultsAPD90...
Loading resultsAPD75...
Loading resultsAPD50...
Loading resultsAPD25...
Loading resultsAPD10...
Loading resultsTriangulation...
Loading resultsMaxV...
Loading resultsMinV...
Loading resultsMaxDiffV...
Loading resultsMinDiffV...
Copy resultsTime...
Copy resultsAPD90...
Copy resultsAPD75...
Copy resultsAPD50...
Copy resultsAPD25...
Copy resultsAPD10...
Copy resultsTriangulation...
Copy resultsMaxV...
Copy resultsMinV...
Copy resultsMaxDiffV...
Copy resultsMinDiffV...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 2055417624, states[0] = -95.008966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073876221, states[0] = -94.994429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092337168, states[0] = -94.974413, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.901268
 - CaMKt in component CaMK (millimolar): 0.006974
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.462013
 - nass in component intracellular_ions (millimolar): 6.462075
 - ki in component intracellular_ions (millimolar): 145.515617
 - kss in component intracellular_ions (millimolar): 145.515596
 - cansr in component intracellular_ions (millimolar): 1.312846
 - cajsr in component intracellular_ions (millimolar): 1.274792
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003619
 - hf in component INa (dimensionless): 0.879991
 - hs in component INa (dimensionless): 0.879985
 - j in component INa (dimensionless): 0.879952
 - hsp in component INa (dimensionless): 0.725807
 - jp in component INa (dimensionless): 0.879930
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709662
 - hLp in component INaL (dimensionless): 0.451260
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620871
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695395
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934179
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001610
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339244
 - xs1 in component IKs (dimensionless): 0.243115
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:12:49 (6132): called boinc_finish(0)

</stderr_txt>
]]>