𝕏

Task 55453608

Name HuVeMOp_20240630163545995179_ORdGradInc_k_25-Pueyo_APDR-conf_627_1
Workunit 26332812
Created 30 Jun 2024, 14:35:52 UTC
Sent 30 Jun 2024, 15:42:33 UTC
Report deadline 4 Jul 2024, 1:18:33 UTC
Received 30 Jun 2024, 20:26:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226910
Run time 2 hours 17 min 52 sec
CPU time 2 hours 14 min 12 sec
Validate state Valid
Credit 60.55
Device peak FLOPS 4.06 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.37 MB
Peak swap size 6.39 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630163545995179_ORdGradInc_k_25-Pueyo_APDR-conf_627.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630163545995179_ORdGradInc_k_25-Pueyo_APDR-conf_627_1_r305480481_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630163545995179_ORdGradInc_k_25-Pueyo_APDR-conf_627_1_r305480481_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 119.032067
     * GNaL_b in INaL: 0.004422
     * Gto_b in Ito: 0.073532
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030255
     * GKs_b in IKs: 0.001878
     * GK1_b in IK1: 0.149273
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 73.303155
     * GKb_b in IKb: 0.003929
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046703
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15159221, states[0] = -94.551624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30640739, states[0] = -72.758344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46142539, states[0] = -72.697998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61790280, states[0] = -94.976536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77351640, states[0] = -95.004119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93115385, states[0] = -39.884012, states[40]= 0.000119
Saving checkpoint... 
Iteration: 109127577, states[0] = -52.279769, states[40]= 0.000017
Saving checkpoint... 
Iteration: 124780966, states[0] = -94.944214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139912371, states[0] = -95.010137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155688704, states[0] = -94.803263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171361397, states[0] = -94.991596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186979200, states[0] = -95.020747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202625385, states[0] = -49.519782, states[40]= 0.000027
Saving checkpoint... 
Iteration: 216408020, states[0] = -95.006397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232104758, states[0] = -28.684589, states[40]= 0.000496
Saving checkpoint... 
Iteration: 247468524, states[0] = -95.018568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262425716, states[0] = -95.010511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277934654, states[0] = -95.012420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293326962, states[0] = -94.973443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308776098, states[0] = -94.935043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324408224, states[0] = -95.006099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339676756, states[0] = -94.753416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355287295, states[0] = -94.945213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371069720, states[0] = 1.109052, states[40]= 0.004497
Saving checkpoint... 
Iteration: 386722172, states[0] = -94.865650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402563434, states[0] = 4.344092, states[40]= 0.004823
Saving checkpoint... 
Iteration: 418474077, states[0] = -95.019180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434081902, states[0] = -6.967383, states[40]= 0.003039
Saving checkpoint... 
Iteration: 448507207, states[0] = 26.889991, states[40]= 0.096271
Saving checkpoint... 
Iteration: 464103859, states[0] = -27.788222, states[40]= 0.000539
Saving checkpoint... 
Iteration: 479712565, states[0] = -94.848936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495458901, states[0] = -95.016791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510654407, states[0] = -86.130608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526260808, states[0] = -94.918948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541417988, states[0] = -95.008475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556493597, states[0] = -95.021679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571680452, states[0] = -94.776458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587103712, states[0] = -27.643491, states[40]= 0.000546
Saving checkpoint... 
Iteration: 602872804, states[0] = -94.994721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618688545, states[0] = -94.800786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634079093, states[0] = -4.808785, states[40]= 0.003503
Saving checkpoint... 
Iteration: 649323215, states[0] = -94.971025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664910597, states[0] = -95.006549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679682166, states[0] = -94.783179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694714565, states[0] = -94.852419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710016520, states[0] = 22.395831, states[40]= 0.016665
Saving checkpoint... 
Iteration: 725642523, states[0] = -68.552820, states[40]= 0.000001
Saving checkpoint... 
Iteration: 741212875, states[0] = -94.849370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756844313, states[0] = -94.982439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772406779, states[0] = -95.005481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787902543, states[0] = -95.004303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803353348, states[0] = -94.986654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818787709, states[0] = -94.945340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833155581, states[0] = -87.773256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848835629, states[0] = -94.977959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864427002, states[0] = -95.010429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879994546, states[0] = -95.021637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895332566, states[0] = -94.976280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909763198, states[0] = -94.921428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924945542, states[0] = -95.014217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939985439, states[0] = -95.020481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955054908, states[0] = 8.262808, states[40]= 0.005091
Saving checkpoint... 
Iteration: 970196496, states[0] = -94.817719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985829360, states[0] = -94.974449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001445081, states[0] = -95.014093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016777714, states[0] = -94.936226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031864814, states[0] = -94.991420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047070046, states[0] = 0.929373, states[40]= 0.004475
Saving checkpoint... 
Iteration: 1062672619, states[0] = -94.690633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078102599, states[0] = -26.548266, states[40]= 0.000598
Saving checkpoint... 
Iteration: 1093720513, states[0] = -94.862529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109120897, states[0] = -44.808789, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1124416292, states[0] = -95.007778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137812806, states[0] = -94.964197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152786668, states[0] = -94.944282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168007724, states[0] = 26.304042, states[40]= 0.087404
Saving checkpoint... 
Iteration: 1183602632, states[0] = -26.580667, states[40]= 0.000597
Saving checkpoint... 
Iteration: 1199172787, states[0] = -94.694554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214801316, states[0] = -94.956047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230412086, states[0] = -95.006664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245687001, states[0] = -94.796805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261072137, states[0] = -0.261292, states[40]= 0.004315
Saving checkpoint... 
Iteration: 1277009929, states[0] = 24.654317, states[40]= 0.055541
Saving checkpoint... 
Iteration: 1292156119, states[0] = -88.467070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307368665, states[0] = -94.992809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322430320, states[0] = -95.010942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337370471, states[0] = -94.993489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352754952, states[0] = -94.911740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367362761, states[0] = -94.990425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383253972, states[0] = -94.910545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398890780, states[0] = -95.000505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414360995, states[0] = -94.989671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429858597, states[0] = -94.988652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445473466, states[0] = -95.018598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461140256, states[0] = -65.766053, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1476510287, states[0] = 24.468777, states[40]= 0.051501
Saving checkpoint... 
Iteration: 1492134057, states[0] = -58.737272, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1507731108, states[0] = -95.212364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523259967, states[0] = -95.084357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538547663, states[0] = -94.813432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553592632, states[0] = -95.191622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568662374, states[0] = -95.294534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584213422, states[0] = -95.238182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599049622, states[0] = 6.657652, states[40]= 0.005708
Saving checkpoint... 
Iteration: 1613940121, states[0] = -95.278365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628955382, states[0] = -95.295789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643990581, states[0] = -95.325585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659065557, states[0] = -4.277655, states[40]= 0.004029
Saving checkpoint... 
Iteration: 1674384694, states[0] = -24.606283, states[40]= 0.000712
Saving checkpoint... 
Iteration: 1689724730, states[0] = -72.945954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1704693433, states[0] = -34.475034, states[40]= 0.000258
Saving checkpoint... 
Iteration: 1719835643, states[0] = -95.275019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735249992, states[0] = 6.383773, states[40]= 0.005682
Saving checkpoint... 
Iteration: 1750789709, states[0] = -95.325725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765708713, states[0] = -95.236169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780828894, states[0] = 17.354552, states[40]= 0.008065
Saving checkpoint... 
Iteration: 1796339886, states[0] = -95.280179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811905371, states[0] = -95.057397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825986764, states[0] = -95.056455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841525437, states[0] = 19.590815, states[40]= 0.007983
Saving checkpoint... 
Iteration: 1856948743, states[0] = -95.029087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872066824, states[0] = 2.430352, states[40]= 0.004656
Saving checkpoint... 
Iteration: 1886999508, states[0] = -95.027836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901006821, states[0] = 27.381085, states[40]= 0.103113
Saving checkpoint... 
Iteration: 1915974548, states[0] = -95.021144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931223539, states[0] = -94.868878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946456178, states[0] = -95.016698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962020668, states[0] = 21.245952, states[40]= 0.010658
Saving checkpoint... 
Iteration: 1977611672, states[0] = -35.522270, states[40]= 0.000222
Saving checkpoint... 
Iteration: 1993199027, states[0] = -94.822614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008251710, states[0] = -94.907626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023850420, states[0] = -94.984818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039280193, states[0] = -94.938098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054111310, states[0] = -35.139813, states[40]= 0.000234
Saving checkpoint... 
Iteration: 2068936523, states[0] = -95.011891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083995061, states[0] = -95.021106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099030187, states[0] = 18.218054, states[40]= 0.006818
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.897535
 - CaMKt in component CaMK (millimolar): 0.006390
 - cass in component intracellular_ions (millimolar): 0.000072
 - nai in component intracellular_ions (millimolar): 6.414867
 - nass in component intracellular_ions (millimolar): 6.414925
 - ki in component intracellular_ions (millimolar): 145.571178
 - kss in component intracellular_ions (millimolar): 145.571159
 - cansr in component intracellular_ions (millimolar): 1.280228
 - cajsr in component intracellular_ions (millimolar): 1.243456
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.003620
 - hf in component INa (dimensionless): 0.879926
 - hs in component INa (dimensionless): 0.879921
 - j in component INa (dimensionless): 0.879893
 - hsp in component INa (dimensionless): 0.725690
 - jp in component INa (dimensionless): 0.879874
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710676
 - hLp in component INaL (dimensionless): 0.454413
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.626193
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.701761
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938526
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999895
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001496
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339736
 - xs1 in component IKs (dimensionless): 0.231742
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:11:52 (1808): called boinc_finish(0)

</stderr_txt>
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