𝕏

Task 55453446

Name HuVeMOp_20240630163542097666_ORdGradInc_k_25-BASE_MID-conf_212_1
Workunit 26332731
Created 30 Jun 2024, 14:35:47 UTC
Sent 30 Jun 2024, 15:31:41 UTC
Report deadline 3 Jul 2024, 15:31:41 UTC
Received 2 Jul 2024, 5:15:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 2 hours 57 min 16 sec
CPU time 1 hours 28 min 47 sec
Validate state Valid
Credit 42.07
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.72 MB
Peak swap size 3.88 MB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630163542097666_ORdGradInc_k_25-BASE_MID-conf_212.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630163542097666_ORdGradInc_k_25-BASE_MID-conf_212_1_r1004831548_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630163542097666_ORdGradInc_k_25-BASE_MID-conf_212_1_r1004831548_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 98.827801
     * GNaL_b in INaL: 0.005310
     * Gto_b in Ito: 0.090532
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032202
     * GKs_b in IKs: 0.001878
     * GK1_b in IK1: 0.170503
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 72.750129
     * GKb_b in IKb: 0.003735
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018226
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8273636, states[0] = -86.608830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16547041, states[0] = 29.496712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24241093, states[0] = -86.445735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33118716, states[0] = -1.098055, states[40]= 0.000119
Saving checkpoint... 
Iteration: 41223744, states[0] = -86.352409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50136865, states[0] = -16.880175, states[40]= 0.000226
Saving checkpoint... 
Iteration: 58428924, states[0] = -86.972622, states[40]= 0.000002
Saving checkpoint... 
Iteration: 66587132, states[0] = 12.804544, states[40]= 0.000012
Saving checkpoint... 
Iteration: 75325232, states[0] = -86.849624, states[40]= 0.000002
Saving checkpoint... 
Iteration: 83584878, states[0] = 13.518082, states[40]= 0.000011
Saving checkpoint... 
Iteration: 91393915, states[0] = -86.965997, states[40]= 0.000002
Saving checkpoint... 
Iteration: 99262586, states[0] = -86.647930, states[40]= 0.000001
Saving checkpoint... 
Iteration: 106891350, states[0] = -86.968206, states[40]= 0.000002
Saving checkpoint... 
Iteration: 114474926, states[0] = -87.027039, states[40]= 0.000002
Saving checkpoint... 
Iteration: 122386187, states[0] = -86.965326, states[40]= 0.000002
Saving checkpoint... 
Iteration: 131394941, states[0] = -86.975573, states[40]= 0.000002
Saving checkpoint... 
Iteration: 140658931, states[0] = -39.887528, states[40]= 0.000380
Saving checkpoint... 
Iteration: 149806286, states[0] = -86.819892, states[40]= 0.000002
Saving checkpoint... 
Iteration: 158303022, states[0] = -86.810489, states[40]= 0.000002
Saving checkpoint... 
Iteration: 166420095, states[0] = -86.998664, states[40]= 0.000002
Saving checkpoint... 
Iteration: 174014818, states[0] = 29.613556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182121031, states[0] = -7.759423, states[40]= 0.000225
Saving checkpoint... 
Iteration: 189563818, states[0] = 22.013882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198401988, states[0] = -86.982272, states[40]= 0.000002
Saving checkpoint... 
Iteration: 205599107, states[0] = 6.092443, states[40]= 0.000056
Saving checkpoint... 
Iteration: 213801978, states[0] = -86.805552, states[40]= 0.000002
Saving checkpoint... 
Iteration: 221422611, states[0] = -86.998353, states[40]= 0.000002
Saving checkpoint... 
Iteration: 230346124, states[0] = -86.907485, states[40]= 0.000002
Saving checkpoint... 
Iteration: 238114622, states[0] = -3.033412, states[40]= 0.000183
Saving checkpoint... 
Iteration: 246547829, states[0] = 27.402627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255010921, states[0] = 27.573880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263775837, states[0] = -86.710116, states[40]= 0.000001
Saving checkpoint... 
Iteration: 273091714, states[0] = 9.808293, states[40]= 0.000027
Saving checkpoint... 
Iteration: 281468649, states[0] = -87.021437, states[40]= 0.000002
Saving checkpoint... 
Iteration: 290145269, states[0] = -28.061759, states[40]= 0.000630
Saving checkpoint... 
Iteration: 298739486, states[0] = -86.517763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 307814989, states[0] = -86.835976, states[40]= 0.000002
Saving checkpoint... 
Iteration: 316181720, states[0] = -66.268507, states[40]= 0.000016
Saving checkpoint... 
Iteration: 325428732, states[0] = -86.996366, states[40]= 0.000002
Saving checkpoint... 
Iteration: 335005939, states[0] = 22.403397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344259333, states[0] = -86.629041, states[40]= 0.000001
Saving checkpoint... 
Iteration: 352448319, states[0] = -87.006822, states[40]= 0.000002
Saving checkpoint... 
Iteration: 360607970, states[0] = 1.187571, states[40]= 0.000119
Saving checkpoint... 
Iteration: 369588457, states[0] = 11.378984, states[40]= 0.000019
Saving checkpoint... 
Iteration: 378164495, states[0] = -45.792666, states[40]= 0.000214
Saving checkpoint... 
Iteration: 386532810, states[0] = 30.671238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395229430, states[0] = -86.442192, states[40]= 0.000001
Saving checkpoint... 
Iteration: 403976292, states[0] = -87.016818, states[40]= 0.000002
Saving checkpoint... 
Iteration: 412305522, states[0] = -86.803450, states[40]= 0.000002
Saving checkpoint... 
Iteration: 419963907, states[0] = -87.010428, states[40]= 0.000002
Saving checkpoint... 
Iteration: 428988085, states[0] = -87.019647, states[40]= 0.000002
Saving checkpoint... 
Iteration: 437434657, states[0] = -86.993140, states[40]= 0.000002
Saving checkpoint... 
Iteration: 446384708, states[0] = -86.949033, states[40]= 0.000002
Saving checkpoint... 
Iteration: 454706466, states[0] = -86.218524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462756019, states[0] = -86.604016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471060250, states[0] = 23.337558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479875071, states[0] = -86.935260, states[40]= 0.000002
Saving checkpoint... 
Iteration: 488733874, states[0] = -86.467559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 497313752, states[0] = -86.820453, states[40]= 0.000002
Saving checkpoint... 
Iteration: 505758151, states[0] = -86.612335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 514516096, states[0] = 30.055465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522581451, states[0] = 14.634401, states[40]= 0.000009
Saving checkpoint... 
Iteration: 531560686, states[0] = 23.180114, states[40]= 0.000001
Saving checkpoint... 
Iteration: 540238278, states[0] = -86.493886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 548162055, states[0] = -43.286233, states[40]= 0.000277
Saving checkpoint... 
Iteration: 557079687, states[0] = 15.427914, states[40]= 0.000007
Saving checkpoint... 
Iteration: 565479217, states[0] = -87.007643, states[40]= 0.000002
Saving checkpoint... 
Iteration: 574707926, states[0] = -86.235982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582695196, states[0] = -84.578785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 591200067, states[0] = -85.881723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599863248, states[0] = -86.911438, states[40]= 0.000002
Saving checkpoint... 
Iteration: 607966996, states[0] = -86.999791, states[40]= 0.000002
Saving checkpoint... 
Iteration: 615583328, states[0] = 13.781818, states[40]= 0.000011
Saving checkpoint... 
Iteration: 623644868, states[0] = -27.701420, states[40]= 0.000620
Saving checkpoint... 
Iteration: 632588076, states[0] = 11.568535, states[40]= 0.000018
Saving checkpoint... 
Iteration: 640987872, states[0] = -87.006001, states[40]= 0.000002
Saving checkpoint... 
Iteration: 649470390, states[0] = -86.998621, states[40]= 0.000002
Saving checkpoint... 
Iteration: 657712967, states[0] = -86.290235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666496199, states[0] = -87.007146, states[40]= 0.000002
Saving checkpoint... 
Iteration: 675210760, states[0] = -86.266109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683821515, states[0] = -86.827688, states[40]= 0.000002
Saving checkpoint... 
Iteration: 692406511, states[0] = -86.955288, states[40]= 0.000002
Saving checkpoint... 
Iteration: 701184545, states[0] = -70.577357, states[40]= 0.000009
Saving checkpoint... 
Iteration: 709332126, states[0] = -86.849767, states[40]= 0.000002
Saving checkpoint... 
Iteration: 718153314, states[0] = -34.947359, states[40]= 0.000547
Saving checkpoint... 
Iteration: 726620654, states[0] = -7.477639, states[40]= 0.000222
Saving checkpoint... 
Iteration: 734864620, states[0] = -86.904731, states[40]= 0.000002
Saving checkpoint... 
Iteration: 742710373, states[0] = -86.257120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751916533, states[0] = -86.959915, states[40]= 0.000002
Saving checkpoint... 
Iteration: 760702654, states[0] = -86.071665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771424367, states[0] = -86.964637, states[40]= 0.000002
Saving checkpoint... 
Iteration: 779357383, states[0] = -86.891021, states[40]= 0.000002
Saving checkpoint... 
Iteration: 788927906, states[0] = -86.966044, states[40]= 0.000002
Saving checkpoint... 
Iteration: 796902845, states[0] = -86.945216, states[40]= 0.000002
Saving checkpoint... 
Iteration: 804576060, states[0] = 17.027826, states[40]= 0.000004
Saving checkpoint... 
Iteration: 812208263, states[0] = -86.224749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820646554, states[0] = -29.075894, states[40]= 0.000638
Saving checkpoint... 
Iteration: 829513593, states[0] = 29.102856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837840388, states[0] = -86.857968, states[40]= 0.000002
Saving checkpoint... 
Iteration: 847021295, states[0] = 31.075571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855911034, states[0] = -86.948731, states[40]= 0.000002
Saving checkpoint... 
Iteration: 864176836, states[0] = -59.524140, states[40]= 0.000039
Saving checkpoint... 
Iteration: 873008308, states[0] = 25.439972, states[40]= -0.000000
Saving checkpoint... 
Iteration: 882042444, states[0] = 28.842193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890476054, states[0] = -86.985586, states[40]= 0.000002
Saving checkpoint... 
Iteration: 899240579, states[0] = -86.485090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 908248945, states[0] = -86.535501, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917102103, states[0] = 4.518253, states[40]= 0.000072
Saving checkpoint... 
Iteration: 925834700, states[0] = -86.841078, states[40]= 0.000002
Saving checkpoint... 
Iteration: 933621754, states[0] = -8.345014, states[40]= 0.000225
Saving checkpoint... 
Iteration: 942632000, states[0] = -17.111458, states[40]= 0.000245
Saving checkpoint... 
Iteration: 952168373, states[0] = -49.799473, states[40]= 0.000135
Saving checkpoint... 
Iteration: 959986522, states[0] = -86.985118, states[40]= 0.000002
Saving checkpoint... 
Iteration: 968634546, states[0] = -19.268734, states[40]= 0.000286
Saving checkpoint... 
Iteration: 978217659, states[0] = -86.311130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986959084, states[0] = -86.971845, states[40]= 0.000002
Saving checkpoint... 
Iteration: 995163941, states[0] = -45.139071, states[40]= 0.000227
Saving checkpoint... 
Iteration: 1003795174, states[0] = -86.733259, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1013575374, states[0] = 17.329587, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1022316754, states[0] = -86.794155, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1030841823, states[0] = -86.848199, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1039088209, states[0] = 11.518998, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1047564262, states[0] = 21.853691, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1056693501, states[0] = -83.386639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1064994584, states[0] = -86.981168, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1073935773, states[0] = -86.953075, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1082232171, states[0] = -86.416294, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1091201064, states[0] = -85.937348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098928949, states[0] = -86.946911, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1108334141, states[0] = -86.828140, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1117529568, states[0] = 31.050519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125270445, states[0] = -86.630713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1133652206, states[0] = -33.908530, states[40]= 0.000574
Saving checkpoint... 
Iteration: 1142209275, states[0] = -86.216513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150548271, states[0] = 27.297652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158967059, states[0] = -86.964596, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1167542599, states[0] = 28.812380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176472926, states[0] = -86.966015, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1185360860, states[0] = -86.870215, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1193965151, states[0] = -86.961471, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1203319624, states[0] = -86.789547, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1211932661, states[0] = -86.942207, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1220060445, states[0] = 23.286526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228489087, states[0] = -86.968871, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1236703821, states[0] = -86.088569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245542979, states[0] = 28.721624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254698008, states[0] = -85.476730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262974818, states[0] = -86.961293, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1272024950, states[0] = 31.260074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280433839, states[0] = -86.938625, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1288026760, states[0] = 31.228647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297373242, states[0] = -86.880362, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1305798329, states[0] = -86.723764, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1313815119, states[0] = -86.771128, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1322350510, states[0] = -86.844885, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1331039191, states[0] = 29.589069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339339014, states[0] = -86.822959, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1347981935, states[0] = -86.958647, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1356563394, states[0] = 22.192868, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1365287643, states[0] = -86.683892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1373647393, states[0] = -29.721197, states[40]= 0.000637
Saving checkpoint... 
Iteration: 1381534549, states[0] = 30.444934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389783179, states[0] = -86.665815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1398212550, states[0] = -86.236462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406034373, states[0] = 30.473178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414717556, states[0] = -86.281129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423620303, states[0] = -7.139462, states[40]= 0.000218
Saving checkpoint... 
Iteration: 1431756744, states[0] = -86.544205, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1440249089, states[0] = -86.501328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1449556887, states[0] = 24.557117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457920525, states[0] = -86.917805, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1467522835, states[0] = 31.208053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476497572, states[0] = -86.955849, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1485202942, states[0] = -86.030854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493191986, states[0] = -81.828711, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.830974
 - CaMKt in component CaMK (millimolar): 0.025939
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 8.027603
 - nass in component intracellular_ions (millimolar): 8.027762
 - ki in component intracellular_ions (millimolar): 143.282411
 - kss in component intracellular_ions (millimolar): 143.282371
 - cansr in component intracellular_ions (millimolar): 2.118462
 - cajsr in component intracellular_ions (millimolar): 2.057890
 - cai in component intracellular_ions (millimolar): 0.000098
 - m in component INa (dimensionless): 0.008159
 - hf in component INa (dimensionless): 0.660674
 - hs in component INa (dimensionless): 0.660644
 - j in component INa (dimensionless): 0.660475
 - hsp in component INa (dimensionless): 0.412689
 - jp in component INa (dimensionless): 0.660353
 - mL in component INaL (dimensionless): 0.000230
 - hL in component INaL (dimensionless): 0.457249
 - hLp in component INaL (dimensionless): 0.223520
 - a in component Ito (dimensionless): 0.001074
 - iF in component Ito (dimensionless): 0.999464
 - iS in component Ito (dimensionless): 0.535722
 - ap in component Ito (dimensionless): 0.000547
 - iFp in component Ito (dimensionless): 0.999465
 - iSp in component Ito (dimensionless): 0.579702
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.877992
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999626
 - jca in component ICaL (dimensionless): 0.999941
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004177
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.505841
 - xs1 in component IKs (dimensionless): 0.332783
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997024
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
05:24:26 (37798): called boinc_finish(0)

</stderr_txt>
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