𝕏

Task 55452964

Name HuVeMOp_20240630162546480596_ORdGradInc_k_25-Pueyo_APDR-conf_105_1
Workunit 26332511
Created 30 Jun 2024, 14:25:48 UTC
Sent 30 Jun 2024, 15:20:28 UTC
Report deadline 4 Jul 2024, 0:56:28 UTC
Received 30 Jun 2024, 17:46:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 25 min 59 sec
CPU time 2 hours 24 min 5 sec
Validate state Valid
Credit 59.45
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630162546480596_ORdGradInc_k_25-Pueyo_APDR-conf_105.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630162546480596_ORdGradInc_k_25-Pueyo_APDR-conf_105_1_r644354272_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630162546480596_ORdGradInc_k_25-Pueyo_APDR-conf_105_1_r644354272_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 91.834407
     * GNaL_b in INaL: 0.004673
     * Gto_b in Ito: 0.091351
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033740
     * GKs_b in IKs: 0.002041
     * GK1_b in IK1: 0.169479
     * Gncx_b in INaCa_i: 0.000957
     * Pnak_b in INaK: 68.614130
     * GKb_b in IKb: 0.003763
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022845
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13558862, states[0] = 5.765132, states[40]= 0.004658
Saving checkpoint... 
Iteration: 27226053, states[0] = -94.823492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41150787, states[0] = -84.902905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54771297, states[0] = -94.862294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68398362, states[0] = -94.933382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82162390, states[0] = -94.073918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95691772, states[0] = -94.724951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109847860, states[0] = -94.907343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123552201, states[0] = 9.591079, states[40]= 0.004783
Saving checkpoint... 
Iteration: 137698880, states[0] = -94.737525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151727145, states[0] = -94.790500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165682245, states[0] = -94.698822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180174591, states[0] = -94.668971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195120899, states[0] = -44.460780, states[40]= 0.000067
Saving checkpoint... 
Iteration: 210145133, states[0] = -72.934842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225530402, states[0] = 17.603313, states[40]= 0.005460
Saving checkpoint... 
Iteration: 240798052, states[0] = -94.873178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255537310, states[0] = 15.322503, states[40]= 0.005024
Saving checkpoint... 
Iteration: 270478037, states[0] = -94.941466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284965627, states[0] = -94.939546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299362206, states[0] = -94.911205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313847482, states[0] = -94.904415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328524198, states[0] = 19.305951, states[40]= 0.006484
Saving checkpoint... 
Iteration: 343389098, states[0] = -94.921331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358107503, states[0] = -30.993052, states[40]= 0.000416
Saving checkpoint... 
Iteration: 372661754, states[0] = -93.837570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387290554, states[0] = -94.866755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402001226, states[0] = 46.224414, states[40]= 0.057453
Saving checkpoint... 
Iteration: 416490242, states[0] = -94.942982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431095420, states[0] = -19.141574, states[40]= 0.001029
Saving checkpoint... 
Iteration: 445740452, states[0] = -94.810085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460679477, states[0] = -94.690091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475628635, states[0] = -52.695143, states[40]= 0.000018
Saving checkpoint... 
Iteration: 490349108, states[0] = -94.905055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505271849, states[0] = -94.848832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520237661, states[0] = -94.805929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535088197, states[0] = -12.140663, states[40]= 0.001940
Saving checkpoint... 
Iteration: 549991730, states[0] = -94.943059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564946909, states[0] = -94.935975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579951170, states[0] = -94.936771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594996575, states[0] = -94.943619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609984114, states[0] = -94.942009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625011557, states[0] = 21.446230, states[40]= 0.034543
Saving checkpoint... 
Iteration: 639704499, states[0] = -94.747613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654735879, states[0] = -94.803140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669417920, states[0] = -94.929445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684338835, states[0] = -94.899647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699201697, states[0] = -94.741807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714008956, states[0] = 22.063862, states[40]= 0.066223
Saving checkpoint... 
Iteration: 728922233, states[0] = -94.930467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743762064, states[0] = -94.837855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758772639, states[0] = -94.849441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773625824, states[0] = -49.658796, states[40]= 0.000030
Saving checkpoint... 
Iteration: 788601784, states[0] = -25.385260, states[40]= 0.000675
Saving checkpoint... 
Iteration: 803297699, states[0] = -94.872366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818352176, states[0] = -94.906247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833124340, states[0] = -48.072896, states[40]= 0.000038
Saving checkpoint... 
Iteration: 848049907, states[0] = 10.552887, states[40]= 0.004796
Saving checkpoint... 
Iteration: 862827844, states[0] = -94.893274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877524951, states[0] = 19.121384, states[40]= 0.006290
Saving checkpoint... 
Iteration: 892582616, states[0] = -7.194759, states[40]= 0.002953
Saving checkpoint... 
Iteration: 907460196, states[0] = -94.938103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922214497, states[0] = -94.766853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937024250, states[0] = 19.293606, states[40]= 0.006469
Saving checkpoint... 
Iteration: 952006554, states[0] = 23.672680, states[40]= 0.120504
Saving checkpoint... 
Iteration: 966886275, states[0] = -94.919852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982108363, states[0] = -31.837732, states[40]= 0.000380
Saving checkpoint... 
Iteration: 997433843, states[0] = -94.932922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012673497, states[0] = -94.659696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027988663, states[0] = -94.942262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043225096, states[0] = -94.785563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058187785, states[0] = -94.711092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073113937, states[0] = -37.352930, states[40]= 0.000190
Saving checkpoint... 
Iteration: 1088381198, states[0] = -94.917975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103523462, states[0] = 19.480317, states[40]= 0.006705
Saving checkpoint... 
Iteration: 1118977047, states[0] = -94.940585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134260456, states[0] = -94.835647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149646042, states[0] = -74.332511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164695733, states[0] = -94.728753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179478835, states[0] = -94.940792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194758243, states[0] = -94.832961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210222205, states[0] = -94.780476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225456940, states[0] = -94.937271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240504290, states[0] = 28.392664, states[40]= 0.180250
Saving checkpoint... 
Iteration: 1255954416, states[0] = -94.936795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271245792, states[0] = -94.816899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286393619, states[0] = -94.922004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301948241, states[0] = -94.935610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317275446, states[0] = -94.851842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332313366, states[0] = -94.883590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347187788, states[0] = -94.710853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362265128, states[0] = -94.840822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377744523, states[0] = -94.815060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393247015, states[0] = -94.818459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408222994, states[0] = -94.781671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423096606, states[0] = -20.306260, states[40]= 0.000943
Saving checkpoint... 
Iteration: 1438524452, states[0] = 19.244701, states[40]= 0.006415
Saving checkpoint... 
Iteration: 1452977866, states[0] = -94.940422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467740094, states[0] = -94.808699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482989134, states[0] = -94.941940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498337324, states[0] = -94.898143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513488739, states[0] = -95.162423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528514683, states[0] = 21.458577, states[40]= 0.019309
Saving checkpoint... 
Iteration: 1543910611, states[0] = -54.479689, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1559203806, states[0] = -46.641490, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1574390496, states[0] = -95.200080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589792223, states[0] = -33.609101, states[40]= 0.000307
Saving checkpoint... 
Iteration: 1604875341, states[0] = -95.040455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619807719, states[0] = -51.954635, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1634753385, states[0] = 4.277478, states[40]= 0.005265
Saving checkpoint... 
Iteration: 1649621026, states[0] = -95.132563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664885053, states[0] = -95.065588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680022704, states[0] = 18.987953, states[40]= 0.008148
Saving checkpoint... 
Iteration: 1695237441, states[0] = -95.155689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710562353, states[0] = -95.183176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725809372, states[0] = -95.114098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741281022, states[0] = -21.075342, states[40]= 0.000959
Saving checkpoint... 
Iteration: 1756488560, states[0] = -95.205031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771794380, states[0] = -95.209095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786949354, states[0] = -94.944415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1802079600, states[0] = -7.671200, states[40]= 0.002959
Saving checkpoint... 
Iteration: 1817108522, states[0] = -34.418317, states[40]= 0.000283
Saving checkpoint... 
Iteration: 1831841417, states[0] = -94.926168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846593495, states[0] = -18.186461, states[40]= 0.001114
Saving checkpoint... 
Iteration: 1861459362, states[0] = -94.947967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876359872, states[0] = -94.915764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891303542, states[0] = -94.880434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906207299, states[0] = -94.755020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921213981, states[0] = -94.766842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935981425, states[0] = -94.941624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950850801, states[0] = -94.905320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965680737, states[0] = -94.693047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980558566, states[0] = 6.906581, states[40]= 0.004733
Saving checkpoint... 
Iteration: 1995524346, states[0] = 19.268555, states[40]= 0.006443
Saving checkpoint... 
Iteration: 2010694720, states[0] = -94.725878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025490072, states[0] = -94.941605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040274235, states[0] = -94.849972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055143929, states[0] = -71.125786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2069963874, states[0] = -94.937681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084692275, states[0] = -94.720314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099564852, states[0] = 3.986438, states[40]= 0.004611
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.818560
 - CaMKt in component CaMK (millimolar): 0.007397
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.697612
 - nass in component intracellular_ions (millimolar): 6.697673
 - ki in component intracellular_ions (millimolar): 145.270708
 - kss in component intracellular_ions (millimolar): 145.270690
 - cansr in component intracellular_ions (millimolar): 1.344701
 - cajsr in component intracellular_ions (millimolar): 1.306758
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003649
 - hf in component INa (dimensionless): 0.878548
 - hs in component INa (dimensionless): 0.878543
 - j in component INa (dimensionless): 0.878514
 - hsp in component INa (dimensionless): 0.723098
 - jp in component INa (dimensionless): 0.878494
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708903
 - hLp in component INaL (dimensionless): 0.453162
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.626097
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.702331
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940303
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999903
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001726
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.309549
 - xs1 in component IKs (dimensionless): 0.231776
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997359
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:46:34 (598100): called boinc_finish(0)

</stderr_txt>
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