𝕏

Task 55452214

Name HuVeMOp_20240630161541061747_ORdGradInc_k_25-Pueyo_APDR-conf_30_1
Workunit 26332143
Created 30 Jun 2024, 14:15:44 UTC
Sent 30 Jun 2024, 15:17:42 UTC
Report deadline 4 Jul 2024, 0:53:42 UTC
Received 3 Jul 2024, 10:03:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226324
Run time 2 hours 47 min 51 sec
CPU time 2 hours 31 min 1 sec
Validate state Valid
Credit 62.87
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161541061747_ORdGradInc_k_25-Pueyo_APDR-conf_30.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161541061747_ORdGradInc_k_25-Pueyo_APDR-conf_30_1_r380003934_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161541061747_ORdGradInc_k_25-Pueyo_APDR-conf_30_1_r380003934_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 95.491145
     * GNaL_b in INaL: 0.005534
     * Gto_b in Ito: 0.087582
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033074
     * GKs_b in IKs: 0.001905
     * GK1_b in IK1: 0.156960
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 72.381613
     * GKb_b in IKb: 0.003704
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018797
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13383264, states[0] = -94.944859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26492849, states[0] = -94.934699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40381472, states[0] = -94.887142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53977636, states[0] = -94.899468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67616711, states[0] = -37.198952, states[40]= 0.000195
Saving checkpoint... 
Iteration: 81128065, states[0] = -48.489181, states[40]= 0.000036
Saving checkpoint... 
Iteration: 94551933, states[0] = 10.632438, states[40]= 0.004862
Saving checkpoint... 
Iteration: 107898823, states[0] = -94.862684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121932149, states[0] = -94.870641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135777655, states[0] = -94.784121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149130140, states[0] = -50.164773, states[40]= 0.000027
Saving checkpoint... 
Iteration: 162290458, states[0] = -94.796013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176415886, states[0] = -94.864045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189618326, states[0] = -38.002680, states[40]= 0.000174
Saving checkpoint... 
Iteration: 203530178, states[0] = 18.479496, states[40]= 0.005746
Saving checkpoint... 
Iteration: 216907253, states[0] = -94.861090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230886762, states[0] = -94.854110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244207083, states[0] = -94.671659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257403566, states[0] = -94.859797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271592336, states[0] = -13.060805, states[40]= 0.001764
Saving checkpoint... 
Iteration: 284738209, states[0] = -94.729707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297646168, states[0] = -68.183357, states[40]= 0.000001
Saving checkpoint... 
Iteration: 310803716, states[0] = -94.806824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323546913, states[0] = 12.681068, states[40]= 0.004915
Saving checkpoint... 
Iteration: 336273114, states[0] = -94.777061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348997172, states[0] = -94.879388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361704881, states[0] = -94.666796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375040588, states[0] = 15.027856, states[40]= 0.005056
Saving checkpoint... 
Iteration: 387782232, states[0] = -94.786864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401094414, states[0] = -15.008549, states[40]= 0.001467
Saving checkpoint... 
Iteration: 414365683, states[0] = -94.845214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427211398, states[0] = -94.680456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441077059, states[0] = -1.172902, states[40]= 0.004077
Saving checkpoint... 
Iteration: 453744693, states[0] = -94.739680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467152638, states[0] = -77.412463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480155322, states[0] = -81.771643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493458167, states[0] = -94.873106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506648539, states[0] = -71.335063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 519292910, states[0] = -94.797193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532545300, states[0] = 13.291165, states[40]= 0.004940
Saving checkpoint... 
Iteration: 545340917, states[0] = -94.832451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558019961, states[0] = 20.984184, states[40]= 0.009061
Saving checkpoint... 
Iteration: 571132928, states[0] = -53.064265, states[40]= 0.000017
Saving checkpoint... 
Iteration: 584253791, states[0] = -94.752715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597686123, states[0] = -94.621258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610354932, states[0] = -94.839939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622897808, states[0] = -94.857607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636256530, states[0] = -94.756398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649176939, states[0] = -94.552445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662002102, states[0] = 42.304093, states[40]= 0.110989
Saving checkpoint... 
Iteration: 674638973, states[0] = -59.661073, states[40]= 0.000005
Saving checkpoint... 
Iteration: 687425082, states[0] = -94.865604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700559600, states[0] = 7.581383, states[40]= 0.004790
Saving checkpoint... 
Iteration: 713674029, states[0] = -94.475351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727883934, states[0] = -94.852575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741076779, states[0] = -1.002404, states[40]= 0.004102
Saving checkpoint... 
Iteration: 753987468, states[0] = -94.877761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766616697, states[0] = -36.385951, states[40]= 0.000218
Saving checkpoint... 
Iteration: 779900691, states[0] = -94.858443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793794402, states[0] = -94.798360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806711168, states[0] = -94.679702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819542462, states[0] = 14.346317, states[40]= 0.005001
Saving checkpoint... 
Iteration: 832257635, states[0] = -94.757726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845036250, states[0] = 16.545800, states[40]= 0.005246
Saving checkpoint... 
Iteration: 857528152, states[0] = 19.064507, states[40]= 0.006020
Saving checkpoint... 
Iteration: 870293843, states[0] = -94.797794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883098451, states[0] = -18.861430, states[40]= 0.001051
Saving checkpoint... 
Iteration: 896208470, states[0] = -94.674029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909494684, states[0] = -94.878646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922902189, states[0] = -94.858822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936219735, states[0] = -94.696635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950050703, states[0] = 11.218271, states[40]= 0.004872
Saving checkpoint... 
Iteration: 963232163, states[0] = -94.719147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976474347, states[0] = -94.875595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990045607, states[0] = 13.175745, states[40]= 0.004935
Saving checkpoint... 
Iteration: 1002864876, states[0] = -94.844414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016293689, states[0] = -94.797545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029689827, states[0] = -94.631630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043576258, states[0] = -0.689014, states[40]= 0.004147
Saving checkpoint... 
Iteration: 1057576387, states[0] = -0.766128, states[40]= 0.004136
Saving checkpoint... 
Iteration: 1070740993, states[0] = -94.733531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083413804, states[0] = -94.862235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096214679, states[0] = -94.686612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108799676, states[0] = -94.802807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121821294, states[0] = -94.819593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135866636, states[0] = -94.845113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149641379, states[0] = -62.386894, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1163053138, states[0] = 10.254188, states[40]= 0.004851
Saving checkpoint... 
Iteration: 1176730532, states[0] = -94.716179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189896281, states[0] = -94.856677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202792960, states[0] = -94.796736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215849217, states[0] = -94.836544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228558219, states[0] = 8.168793, states[40]= 0.004806
Saving checkpoint... 
Iteration: 1242685398, states[0] = -94.618319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256273686, states[0] = -94.777023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269298228, states[0] = -94.801429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282975240, states[0] = -94.875515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296428656, states[0] = -94.866067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310121309, states[0] = -40.944456, states[40]= 0.000114
Saving checkpoint... 
Iteration: 1323427095, states[0] = -94.865654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336893423, states[0] = -94.855587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350452561, states[0] = -94.871386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363757283, states[0] = -94.756867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376915430, states[0] = -94.862484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390523805, states[0] = 20.178237, states[40]= 0.007021
Saving checkpoint... 
Iteration: 1403680449, states[0] = -94.593028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417342644, states[0] = -94.832795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431046494, states[0] = 12.840574, states[40]= 0.004921
Saving checkpoint... 
Iteration: 1444666543, states[0] = -93.491711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459429247, states[0] = -94.866095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473036089, states[0] = 16.600407, states[40]= 0.005255
Saving checkpoint... 
Iteration: 1486697880, states[0] = -94.650520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500319595, states[0] = 21.399617, states[40]= 0.011713
Saving checkpoint... 
Iteration: 1513684684, states[0] = -94.966100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527121738, states[0] = -63.178487, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1539719723, states[0] = -61.316607, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1553237731, states[0] = -89.336167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566128427, states[0] = -74.496673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1579598694, states[0] = -37.297081, states[40]= 0.000193
Saving checkpoint... 
Iteration: 1592358636, states[0] = -95.133319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605600386, states[0] = -47.313855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618453136, states[0] = -95.129393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631382219, states[0] = -95.158795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644372301, states[0] = -8.636863, states[40]= 0.002968
Saving checkpoint... 
Iteration: 1656914173, states[0] = 22.124589, states[40]= 0.021918
Saving checkpoint... 
Iteration: 1669968812, states[0] = -94.970440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683176799, states[0] = -94.992552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1695483478, states[0] = -95.009621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708696237, states[0] = -95.039183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721546266, states[0] = -94.490608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1734031966, states[0] = 16.163684, states[40]= 0.006536
Saving checkpoint... 
Iteration: 1746783076, states[0] = -95.008683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759842300, states[0] = 11.338313, states[40]= 0.005812
Saving checkpoint... 
Iteration: 1772706084, states[0] = 26.417657, states[40]= 0.119359
Saving checkpoint... 
Iteration: 1785515450, states[0] = -95.076765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798339052, states[0] = -91.553976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811534301, states[0] = 16.610531, states[40]= 0.005289
Saving checkpoint... 
Iteration: 1825020287, states[0] = 20.636747, states[40]= 0.008636
Saving checkpoint... 
Iteration: 1837967844, states[0] = -94.898186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850958250, states[0] = -94.888526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864126279, states[0] = -46.682389, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1876883231, states[0] = -94.858900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890007935, states[0] = 23.420047, states[40]= 0.085245
Saving checkpoint... 
Iteration: 1903069505, states[0] = 2.926808, states[40]= 0.004547
Saving checkpoint... 
Iteration: 1916490597, states[0] = -94.879548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929430785, states[0] = -94.867596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942960606, states[0] = -94.873453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956498586, states[0] = -94.879001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969460618, states[0] = -94.872875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981921607, states[0] = -94.863989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995283340, states[0] = -94.786961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007767421, states[0] = -94.769276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020177049, states[0] = -94.553410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034316864, states[0] = -94.815766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047055145, states[0] = 9.442870, states[40]= 0.004835
Saving checkpoint... 
Iteration: 2060635772, states[0] = -56.137715, states[40]= 0.000010
Saving checkpoint... 
Iteration: 2073929884, states[0] = -94.865756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087049436, states[0] = 11.712306, states[40]= 0.004884
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.754283
 - CaMKt in component CaMK (millimolar): 0.007181
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.583822
 - nass in component intracellular_ions (millimolar): 6.583882
 - ki in component intracellular_ions (millimolar): 145.389752
 - kss in component intracellular_ions (millimolar): 145.389733
 - cansr in component intracellular_ions (millimolar): 1.326016
 - cajsr in component intracellular_ions (millimolar): 1.287884
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003673
 - hf in component INa (dimensionless): 0.877417
 - hs in component INa (dimensionless): 0.877411
 - j in component INa (dimensionless): 0.877379
 - hsp in component INa (dimensionless): 0.720976
 - jp in component INa (dimensionless): 0.877357
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.706049
 - hLp in component INaL (dimensionless): 0.447737
 - a in component Ito (dimensionless): 0.000630
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.621086
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.695850
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936379
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001653
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.324613
 - xs1 in component IKs (dimensionless): 0.239636
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997376
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:03:21 (35146): called boinc_finish(0)

</stderr_txt>
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