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Task 55452052

Name HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931_1
Workunit 26332067
Created 30 Jun 2024, 14:10:52 UTC
Sent 30 Jun 2024, 15:25:40 UTC
Report deadline 4 Jul 2024, 1:01:40 UTC
Received 1 Jul 2024, 1:30:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227318
Run time 1 hours 1 min 52 sec
CPU time 58 min 57 sec
Validate state Valid
Credit 66.05
Device peak FLOPS 5.60 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.16 MB
Peak swap size 391.77 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931_1_r188834265_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931_1_r188834265_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.775016
     * GNaL_b in INaL: 0.004804
     * Gto_b in Ito: 0.072830
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033969
     * GKs_b in IKs: 0.002111
     * GK1_b in IK1: 0.181482
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 66.824872
     * GKb_b in IKb: 0.003900
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041910
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 47683162, states[0] = -94.874375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96135398, states[0] = -74.045188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142133758, states[0] = -70.966796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 191018276, states[0] = 21.261767, states[40]= 0.013169
Saving checkpoint... 
Iteration: 231764385, states[0] = -94.966926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273337092, states[0] = -95.011306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304550111, states[0] = 8.792379, states[40]= 0.005213
Saving checkpoint... 
Iteration: 344780806, states[0] = -94.979829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382697638, states[0] = -94.884550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422276010, states[0] = -94.976205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464477198, states[0] = -95.043795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499889910, states[0] = -95.028566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531728977, states[0] = -94.929919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559923606, states[0] = -95.035895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586997019, states[0] = -95.045773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608693892, states[0] = -94.878085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626789505, states[0] = -94.985756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645940293, states[0] = -95.038728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667794975, states[0] = -94.989291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689426428, states[0] = -95.036348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709433486, states[0] = -95.037576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728387353, states[0] = -95.027794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749517284, states[0] = 21.555522, states[40]= 0.014802
Saving checkpoint... 
Iteration: 796406481, states[0] = -95.032324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843818749, states[0] = -95.002597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891156480, states[0] = -94.711991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938005033, states[0] = 30.518121, states[40]= 0.129744
Saving checkpoint... 
Iteration: 986100721, states[0] = -31.427249, states[40]= 0.000351
Saving checkpoint... 
Iteration: 1034501064, states[0] = 50.418113, states[40]= 0.025353
Saving checkpoint... 
Iteration: 1081847348, states[0] = -95.014972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127215887, states[0] = -94.912287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170670729, states[0] = -94.834326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209771593, states[0] = -94.972354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246220332, states[0] = -94.918369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285750804, states[0] = -94.953776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321707649, states[0] = -94.900082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341532671, states[0] = 16.326330, states[40]= 0.006407
Saving checkpoint... 
Iteration: 1379060842, states[0] = 3.513503, states[40]= 0.004818
Saving checkpoint... 
Iteration: 1417599063, states[0] = -29.680921, states[40]= 0.000424
Saving checkpoint... 
Iteration: 1449616073, states[0] = -48.166106, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1489425510, states[0] = -95.035782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526048388, states[0] = -95.234886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555796400, states[0] = -95.282884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595931218, states[0] = -95.241431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1629100557, states[0] = -50.180139, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1659496202, states[0] = -95.199317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686769754, states[0] = -95.152626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714436324, states[0] = -95.249335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741108507, states[0] = -95.217271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767215742, states[0] = -95.226586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791728583, states[0] = -93.342161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814593702, states[0] = -26.758968, states[40]= 0.000564
Saving checkpoint... 
Iteration: 1834461349, states[0] = -95.061571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870453605, states[0] = -95.047186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906114483, states[0] = -46.566800, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1938823928, states[0] = -95.005510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965199941, states[0] = -94.887988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989945123, states[0] = -95.038991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006242254, states[0] = -94.944664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022210906, states[0] = -94.904681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2042890117, states[0] = -95.027857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065636679, states[0] = -75.791452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086935217, states[0] = -95.037155, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.921139
 - CaMKt in component CaMK (millimolar): 0.006305
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.722935
 - nass in component intracellular_ions (millimolar): 6.722992
 - ki in component intracellular_ions (millimolar): 145.262185
 - kss in component intracellular_ions (millimolar): 145.262166
 - cansr in component intracellular_ions (millimolar): 1.283274
 - cajsr in component intracellular_ions (millimolar): 1.247364
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003611
 - hf in component INa (dimensionless): 0.880335
 - hs in component INa (dimensionless): 0.880331
 - j in component INa (dimensionless): 0.880309
 - hsp in component INa (dimensionless): 0.726466
 - jp in component INa (dimensionless): 0.880294
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713944
 - hLp in component INaL (dimensionless): 0.463661
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.636357
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.714409
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.943719
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999913
 - jca in component ICaL (dimensionless): 0.999984
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001508
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.323411
 - xs1 in component IKs (dimensionless): 0.218633
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:46:24 (51865): called boinc_finish(0)

</stderr_txt>
]]>


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