𝕏

Task 55452051

Name HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931_0
Workunit 26332067
Created 30 Jun 2024, 14:10:52 UTC
Sent 30 Jun 2024, 15:13:34 UTC
Report deadline 4 Jul 2024, 0:49:34 UTC
Received 2 Jul 2024, 22:27:24 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 242162
Run time 2 hours 3 min 25 sec
CPU time 1 hours 54 min 51 sec
Validate state Valid
Credit 66.05
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931_0_r1282285015_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931_0_r1282285015_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.775016
     * GNaL_b in INaL: 0.004804
     * Gto_b in Ito: 0.072830
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033969
     * GKs_b in IKs: 0.002111
     * GK1_b in IK1: 0.181482
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 66.824872
     * GKb_b in IKb: 0.003900
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041910
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9557470, states[0] = 4.006005, states[40]= 0.004852


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931_0_r1282285015_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931_0_r1282285015_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.775016
     * GNaL_b in INaL: 0.004804
     * Gto_b in Ito: 0.072830
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033969
     * GKs_b in IKs: 0.002111
     * GK1_b in IK1: 0.181482
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 66.824872
     * GKb_b in IKb: 0.003900
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041910
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 9557470
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 4.006005 (After loading)
 - states[40]: 0.004852 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 27191060, states[0] = -94.903288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45144803, states[0] = -91.678845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62742817, states[0] = -94.955669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81300791, states[0] = -94.998583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99732360, states[0] = -94.937476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113762448, states[0] = -94.967349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131719080, states[0] = -94.918499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149809272, states[0] = -94.998712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168317847, states[0] = -95.002910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186578977, states[0] = -9.040975, states[40]= 0.002641
Saving checkpoint... 
Iteration: 204838643, states[0] = -95.012113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223264739, states[0] = -94.967254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241466319, states[0] = -95.042664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258690862, states[0] = -94.873018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277423448, states[0] = -95.036024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295415484, states[0] = -95.034468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313038862, states[0] = 13.786222, states[40]= 0.005776
Saving checkpoint... 
Iteration: 330291593, states[0] = -94.987288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347732044, states[0] = -94.933755, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931_0_r1282285015_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630161047256207_ORdGradInc_k_25-Pueyo_APDR-conf_931_0_r1282285015_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.775016
     * GNaL_b in INaL: 0.004804
     * Gto_b in Ito: 0.072830
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033969
     * GKs_b in IKs: 0.002111
     * GK1_b in IK1: 0.181482
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 66.824872
     * GKb_b in IKb: 0.003900
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.041910
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 347732044
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.933755 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 362846228, states[0] = -95.014906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379501261, states[0] = 50.884180, states[40]= 0.035805
Saving checkpoint... 
Iteration: 397099346, states[0] = -29.979400, states[40]= 0.000411
Saving checkpoint... 
Iteration: 414859171, states[0] = -95.019551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426556800, states[0] = 5.587452, states[40]= 0.004986
Saving checkpoint... 
Iteration: 444819108, states[0] = -95.002976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463622170, states[0] = -55.324586, states[40]= 0.000010
Saving checkpoint... 
Iteration: 482558276, states[0] = 4.845148, states[40]= 0.004930
Saving checkpoint... 
Iteration: 501707242, states[0] = -94.899872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520260275, states[0] = -94.963097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538957442, states[0] = -95.041308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557675455, states[0] = -94.844260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576825776, states[0] = -95.006127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595822844, states[0] = -95.004729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614999416, states[0] = -95.045980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634261032, states[0] = -94.963717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653129626, states[0] = -64.776437, states[40]= 0.000002
Saving checkpoint... 
Iteration: 671487770, states[0] = -95.044827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690382719, states[0] = -95.026580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709407510, states[0] = -95.032591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728398811, states[0] = -95.030625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747573079, states[0] = -4.098153, states[40]= 0.003713
Saving checkpoint... 
Iteration: 766576474, states[0] = -6.812162, states[40]= 0.003134
Saving checkpoint... 
Iteration: 785207179, states[0] = -94.899632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801459654, states[0] = -95.041474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816694481, states[0] = -94.878992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827576321, states[0] = -6.682609, states[40]= 0.003163
Saving checkpoint... 
Iteration: 844772366, states[0] = -94.973153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862032400, states[0] = 16.432645, states[40]= 0.006444
Saving checkpoint... 
Iteration: 879026703, states[0] = 18.556269, states[40]= 0.007563
Saving checkpoint... 
Iteration: 895776836, states[0] = -94.976598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913555650, states[0] = 6.155710, states[40]= 0.005027
Saving checkpoint... 
Iteration: 930143009, states[0] = -87.628173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947274596, states[0] = -94.974853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964037887, states[0] = 14.198686, states[40]= 0.005854
Saving checkpoint... 
Iteration: 981004080, states[0] = 33.836817, states[40]= 0.130363
Saving checkpoint... 
Iteration: 997818495, states[0] = -95.002393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015314716, states[0] = -95.000454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032122359, states[0] = -55.551380, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1048522721, states[0] = 19.899142, states[40]= 0.009119
Saving checkpoint... 
Iteration: 1065169018, states[0] = -94.830537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082081105, states[0] = -11.036830, states[40]= 0.002220
Saving checkpoint... 
Iteration: 1098324873, states[0] = -95.005443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115691634, states[0] = -94.873910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132332151, states[0] = -95.008737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148883424, states[0] = -95.026542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165875125, states[0] = -95.024202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177337935, states[0] = -95.011186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194275473, states[0] = -94.975407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210874319, states[0] = -95.023943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227706296, states[0] = -94.898050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244610843, states[0] = -42.274008, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1260914397, states[0] = -95.033756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275493277, states[0] = -95.045074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292365662, states[0] = -95.021249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309908024, states[0] = -95.032402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327032477, states[0] = 16.402539, states[40]= 0.006433
Saving checkpoint... 
Iteration: 1344281193, states[0] = -94.979608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362756938, states[0] = -94.959625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380146343, states[0] = -91.859158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398279309, states[0] = -94.978199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415498726, states[0] = -95.045518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433408777, states[0] = -95.032501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450747875, states[0] = -94.950748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467861813, states[0] = -95.019910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485312063, states[0] = -94.998821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503165178, states[0] = -95.101880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520255833, states[0] = -95.092705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537657821, states[0] = -95.108896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555580592, states[0] = -25.066329, states[40]= 0.000670
Saving checkpoint... 
Iteration: 1572884574, states[0] = -95.280613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591139423, states[0] = -95.249142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608643947, states[0] = 8.276283, states[40]= 0.006027
Saving checkpoint... 
Iteration: 1626853603, states[0] = -95.263922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644085599, states[0] = -31.697889, states[40]= 0.000346
Saving checkpoint... 
Iteration: 1661117123, states[0] = 21.497724, states[40]= 0.016673
Saving checkpoint... 
Iteration: 1672828397, states[0] = 16.573170, states[40]= 0.008124
Saving checkpoint... 
Iteration: 1689416306, states[0] = -73.308104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1706362101, states[0] = -95.271479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723609079, states[0] = -61.779646, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1740982363, states[0] = -27.853787, states[40]= 0.000519
Saving checkpoint... 
Iteration: 1757902739, states[0] = -95.209292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775391080, states[0] = -95.290121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793377531, states[0] = -95.282113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810468821, states[0] = -95.081372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827315853, states[0] = -95.025696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844580648, states[0] = -11.546258, states[40]= 0.002127
Saving checkpoint... 
Iteration: 1861752138, states[0] = -94.964123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878506508, states[0] = 27.319205, states[40]= 0.108999
Saving checkpoint... 
Iteration: 1890160911, states[0] = -94.801660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904255097, states[0] = -94.960285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920707580, states[0] = -94.901333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937677298, states[0] = -94.848132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954536063, states[0] = 14.948550, states[40]= 0.006017
Saving checkpoint... 
Iteration: 1971526456, states[0] = 18.638156, states[40]= 0.007632
Saving checkpoint... 
Iteration: 1988646020, states[0] = -91.580233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005881191, states[0] = -95.025604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022654662, states[0] = -94.623302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039932260, states[0] = -95.036716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057132566, states[0] = -69.000123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2074408000, states[0] = -95.031995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2091037959, states[0] = 14.168380, states[40]= 0.005848
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.921139
 - CaMKt in component CaMK (millimolar): 0.006305
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.722935
 - nass in component intracellular_ions (millimolar): 6.722992
 - ki in component intracellular_ions (millimolar): 145.262185
 - kss in component intracellular_ions (millimolar): 145.262166
 - cansr in component intracellular_ions (millimolar): 1.283274
 - cajsr in component intracellular_ions (millimolar): 1.247364
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003611
 - hf in component INa (dimensionless): 0.880335
 - hs in component INa (dimensionless): 0.880331
 - j in component INa (dimensionless): 0.880309
 - hsp in component INa (dimensionless): 0.726466
 - jp in component INa (dimensionless): 0.880294
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713944
 - hLp in component INaL (dimensionless): 0.463661
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.636357
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.714409
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.943719
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999913
 - jca in component ICaL (dimensionless): 0.999984
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001508
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.323411
 - xs1 in component IKs (dimensionless): 0.218633
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:43:27 (2527): called boinc_finish(0)

</stderr_txt>
]]>


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