𝕏

Task 55451309

Name HuVeMOp_20240630155548682589_ORdGradInc_k_25-Pueyo_APDR-conf_253_0
Workunit 26331719
Created 30 Jun 2024, 13:55:57 UTC
Sent 30 Jun 2024, 15:06:02 UTC
Report deadline 4 Jul 2024, 0:42:02 UTC
Received 30 Jun 2024, 23:05:50 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234919
Run time 2 hours 42 min 18 sec
CPU time 2 hours 29 min 24 sec
Validate state Valid
Credit 61.36
Device peak FLOPS 3.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.33 MB
Peak swap size 5.28 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630155548682589_ORdGradInc_k_25-Pueyo_APDR-conf_253.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630155548682589_ORdGradInc_k_25-Pueyo_APDR-conf_253_0_r87180243_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630155548682589_ORdGradInc_k_25-Pueyo_APDR-conf_253_0_r87180243_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 96.790248
     * GNaL_b in INaL: 0.005521
     * Gto_b in Ito: 0.093991
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032877
     * GKs_b in IKs: 0.001888
     * GK1_b in IK1: 0.180043
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 67.058056
     * GKb_b in IKb: 0.003671
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027118
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7077222, states[0] = -2.377865, states[40]= 0.003766
Saving checkpoint... 
Iteration: 21450779, states[0] = -95.051462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35945765, states[0] = -95.038057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50613978, states[0] = -33.615089, states[40]= 0.000320
Saving checkpoint... 
Iteration: 65046088, states[0] = 12.821925, states[40]= 0.004798
Saving checkpoint... 
Iteration: 79110653, states[0] = -29.994288, states[40]= 0.000480
Saving checkpoint... 
Iteration: 93603887, states[0] = -23.471841, states[40]= 0.000784
Saving checkpoint... 
Iteration: 108259800, states[0] = -94.926410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122841933, states[0] = -94.988265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137155617, states[0] = -84.567484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151643993, states[0] = -65.334940, states[40]= 0.000002
Saving checkpoint... 
Iteration: 166158325, states[0] = -89.001648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180845375, states[0] = -94.988786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194958586, states[0] = -95.021901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209201304, states[0] = -94.835092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223722979, states[0] = -94.874049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238425102, states[0] = -95.015258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252632356, states[0] = -51.579540, states[40]= 0.000023
Saving checkpoint... 
Iteration: 267207182, states[0] = -94.846249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281713948, states[0] = -94.858580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296066075, states[0] = 4.858778, states[40]= 0.004623
Saving checkpoint... 
Iteration: 310536967, states[0] = 16.145180, states[40]= 0.005019
Saving checkpoint... 
Iteration: 325098823, states[0] = -18.477364, states[40]= 0.001083
Saving checkpoint... 
Iteration: 339500901, states[0] = 45.178115, states[40]= 0.024695
Saving checkpoint... 
Iteration: 354043520, states[0] = 13.887462, states[40]= 0.004832
Saving checkpoint... 
Iteration: 368414171, states[0] = -95.012515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382955762, states[0] = -95.021116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397396178, states[0] = -95.007601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411340649, states[0] = -94.986047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425825054, states[0] = -94.977619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440530767, states[0] = 18.056823, states[40]= 0.005429
Saving checkpoint... 
Iteration: 455088049, states[0] = -8.667522, states[40]= 0.002602
Saving checkpoint... 
Iteration: 469565276, states[0] = 5.225422, states[40]= 0.004641
Saving checkpoint... 
Iteration: 483985088, states[0] = -95.025386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498722662, states[0] = -94.873237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513249467, states[0] = -94.911728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527921647, states[0] = -95.014189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542255688, states[0] = -94.919238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556777288, states[0] = -94.941934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571508204, states[0] = 22.411762, states[40]= 0.081114
Saving checkpoint... 
Iteration: 585811885, states[0] = -94.969311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600387776, states[0] = -95.004857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614974229, states[0] = -95.023807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629677848, states[0] = -94.776426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644044729, states[0] = 13.452606, states[40]= 0.004814
Saving checkpoint... 
Iteration: 658696189, states[0] = -94.824388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672969854, states[0] = -95.023123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682634380, states[0] = -53.816093, states[40]= 0.000016
Saving checkpoint... 
Iteration: 696707343, states[0] = -94.846183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711233031, states[0] = -94.889196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725927160, states[0] = -95.015281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740337525, states[0] = -94.984196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754727972, states[0] = -94.881495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769264380, states[0] = -94.928803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783925580, states[0] = -95.014882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798296546, states[0] = -94.958160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812211946, states[0] = -94.854557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826657948, states[0] = -88.401186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841200571, states[0] = -94.833027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855900740, states[0] = -95.008550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869828663, states[0] = -94.979324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884531581, states[0] = 17.822085, states[40]= 0.005355
Saving checkpoint... 
Iteration: 899071601, states[0] = 2.166862, states[40]= 0.004438
Saving checkpoint... 
Iteration: 913625941, states[0] = -44.706347, states[40]= 0.000067
Saving checkpoint... 
Iteration: 927822717, states[0] = -94.975839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942486732, states[0] = -95.025227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956770002, states[0] = -94.934507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971282975, states[0] = -94.946787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985635627, states[0] = -55.214344, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1000164301, states[0] = -93.780195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014637090, states[0] = -56.877077, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1029218194, states[0] = -94.865344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043903597, states[0] = -95.009196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058354661, states[0] = -94.992076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072548976, states[0] = 11.890072, states[40]= 0.004775
Saving checkpoint... 
Iteration: 1087024906, states[0] = 19.564447, states[40]= 0.006346
Saving checkpoint... 
Iteration: 1101540586, states[0] = 14.922293, states[40]= 0.004894
Saving checkpoint... 
Iteration: 1115811878, states[0] = -94.968878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124648380, states[0] = -71.534139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1133540656, states[0] = 14.898023, states[40]= 0.004893
Saving checkpoint... 
Iteration: 1142355305, states[0] = -94.992289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151284435, states[0] = -94.947926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164220111, states[0] = -94.868475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177357766, states[0] = -94.993317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189307408, states[0] = -94.965791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203914777, states[0] = -95.011992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217874478, states[0] = -94.999836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227616685, states[0] = -35.441496, states[40]= 0.000255
Saving checkpoint... 
Iteration: 1241280410, states[0] = -94.944266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255864335, states[0] = -94.995954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268034004, states[0] = 17.092454, states[40]= 0.005175
Saving checkpoint... 
Iteration: 1282005528, states[0] = 25.178893, states[40]= 0.149857
Saving checkpoint... 
Iteration: 1296110536, states[0] = -29.554295, states[40]= 0.000501
Saving checkpoint... 
Iteration: 1310414715, states[0] = -95.011891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324407229, states[0] = -95.009954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338184717, states[0] = -94.799030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352393869, states[0] = -95.006143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366527437, states[0] = 18.956160, states[40]= 0.005841
Saving checkpoint... 
Iteration: 1380660153, states[0] = -91.189783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394711497, states[0] = -94.853273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408838826, states[0] = -94.984323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422696980, states[0] = -94.825373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436964902, states[0] = -95.021754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450927732, states[0] = -95.014824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465125566, states[0] = -44.315803, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1479284651, states[0] = -94.947849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493442345, states[0] = -95.017798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1507513312, states[0] = 22.100117, states[40]= 0.025927
Saving checkpoint... 
Iteration: 1521505580, states[0] = -95.144179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535673393, states[0] = -95.236169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549190968, states[0] = -95.256207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563379201, states[0] = -15.151397, states[40]= 0.001629
Saving checkpoint... 
Iteration: 1577453733, states[0] = 5.380222, states[40]= 0.005311
Saving checkpoint... 
Iteration: 1591276817, states[0] = -12.860638, states[40]= 0.002032
Saving checkpoint... 
Iteration: 1605136416, states[0] = -90.953635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619195676, states[0] = -33.637208, states[40]= 0.000315
Saving checkpoint... 
Iteration: 1633304616, states[0] = -43.761253, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1647426549, states[0] = -73.321300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1661207424, states[0] = -47.126760, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1675264317, states[0] = -1.550177, states[40]= 0.004515
Saving checkpoint... 
Iteration: 1689270687, states[0] = -95.254336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703353008, states[0] = -95.238228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717459514, states[0] = -95.244554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731523448, states[0] = -95.203067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1745583794, states[0] = -95.133244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759661500, states[0] = -95.078515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773697557, states[0] = -35.800959, states[40]= 0.000242
Saving checkpoint... 
Iteration: 1787618715, states[0] = -95.196237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801258585, states[0] = -94.978952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1815330729, states[0] = -95.016051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829415982, states[0] = -95.036938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843529609, states[0] = 18.155739, states[40]= 0.005520
Saving checkpoint... 
Iteration: 1857229078, states[0] = -94.893647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871458321, states[0] = -95.027575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885473090, states[0] = -95.027365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899222381, states[0] = -94.874861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913057171, states[0] = 8.653540, states[40]= 0.004738
Saving checkpoint... 
Iteration: 1927022960, states[0] = 19.966061, states[40]= 0.006942
Saving checkpoint... 
Iteration: 1941193002, states[0] = -94.817654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954859363, states[0] = -94.993908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969007175, states[0] = 23.070098, states[40]= 0.104594
Saving checkpoint... 
Iteration: 1982965834, states[0] = -95.021653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996970655, states[0] = -95.022278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010930511, states[0] = -95.015018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025069025, states[0] = 3.457496, states[40]= 0.004540
Saving checkpoint... 
Iteration: 2038887148, states[0] = -95.003471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052931890, states[0] = -95.015193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067135762, states[0] = -55.367504, states[40]= 0.000012
Saving checkpoint... 
Iteration: 2081244526, states[0] = -94.904059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095401391, states[0] = -95.007667, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.901683
 - CaMKt in component CaMK (millimolar): 0.007410
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.739196
 - nass in component intracellular_ions (millimolar): 6.739257
 - ki in component intracellular_ions (millimolar): 145.230652
 - kss in component intracellular_ions (millimolar): 145.230633
 - cansr in component intracellular_ions (millimolar): 1.339490
 - cajsr in component intracellular_ions (millimolar): 1.301057
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003619
 - hf in component INa (dimensionless): 0.879998
 - hs in component INa (dimensionless): 0.879993
 - j in component INa (dimensionless): 0.879965
 - hsp in component INa (dimensionless): 0.725826
 - jp in component INa (dimensionless): 0.879947
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710245
 - hLp in component INaL (dimensionless): 0.453058
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621929
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697310
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936695
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001701
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.317428
 - xs1 in component IKs (dimensionless): 0.240629
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:11:59 (4756): called boinc_finish(0)

</stderr_txt>
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