𝕏

Task 55451122

Name HuVeMOp_20240630155542641650_ORdGradInc_k_25-Pueyo_APDR-conf_386_1
Workunit 26331625
Created 30 Jun 2024, 13:55:51 UTC
Sent 30 Jun 2024, 15:04:02 UTC
Report deadline 4 Jul 2024, 0:40:02 UTC
Received 3 Jul 2024, 15:20:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 225166
Run time 1 hours 50 min 58 sec
CPU time 1 hours 50 min 29 sec
Validate state Valid
Credit 60.98
Device peak FLOPS 3.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.84 MB
Peak swap size 6.21 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630155542641650_ORdGradInc_k_25-Pueyo_APDR-conf_386.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630155542641650_ORdGradInc_k_25-Pueyo_APDR-conf_386_1_r1230133743_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630155542641650_ORdGradInc_k_25-Pueyo_APDR-conf_386_1_r1230133743_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.851965
     * GNaL_b in INaL: 0.004984
     * Gto_b in Ito: 0.082972
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032974
     * GKs_b in IKs: 0.001993
     * GK1_b in IK1: 0.148403
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 68.974057
     * GKb_b in IKb: 0.003847
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019097
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10926507, states[0] = -94.865382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26510489, states[0] = 22.437001, states[40]= 0.047130
Saving checkpoint... 
Iteration: 42002816, states[0] = 38.311149, states[40]= 0.136756
Saving checkpoint... 
Iteration: 53180754, states[0] = -94.540004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68676229, states[0] = -94.503815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84499114, states[0] = -94.801745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100215675, states[0] = -94.608275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115751205, states[0] = -94.666582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131264309, states[0] = -94.682766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147079350, states[0] = -5.641373, states[40]= 0.003331
Saving checkpoint... 
Iteration: 162501747, states[0] = 46.668802, states[40]= 0.078933
Saving checkpoint... 
Iteration: 177905346, states[0] = -94.775016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193323829, states[0] = -94.736404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208966675, states[0] = -94.789223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224500928, states[0] = 47.423512, states[40]= 0.023366
Saving checkpoint... 
Iteration: 239860332, states[0] = -94.757055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255388685, states[0] = -94.768893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270818192, states[0] = -94.732124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286354060, states[0] = -94.753875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301890842, states[0] = -94.769604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317619616, states[0] = -44.254825, states[40]= 0.000066
Saving checkpoint... 
Iteration: 332838866, states[0] = -94.745521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347984696, states[0] = -94.791822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363884602, states[0] = -94.767252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379765638, states[0] = -94.682255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395319299, states[0] = -94.732801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410682482, states[0] = -94.524439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426480643, states[0] = -94.791160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441825322, states[0] = -94.736932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457330874, states[0] = -94.740547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473142682, states[0] = -69.420808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 488527451, states[0] = 18.529017, states[40]= 0.006566
Saving checkpoint... 
Iteration: 503954200, states[0] = -94.786515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519849960, states[0] = -94.751574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535546898, states[0] = 11.389022, states[40]= 0.005099
Saving checkpoint... 
Iteration: 550810139, states[0] = -94.725871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566337588, states[0] = -94.744603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582033189, states[0] = 16.642243, states[40]= 0.005785
Saving checkpoint... 
Iteration: 597819605, states[0] = -94.732881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613090105, states[0] = -15.151965, states[40]= 0.001475
Saving checkpoint... 
Iteration: 628711217, states[0] = -94.593871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640233535, states[0] = -94.635731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656687497, states[0] = -94.539853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672972829, states[0] = -94.789756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688839558, states[0] = -94.745681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704796139, states[0] = -94.714058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720430935, states[0] = -94.781251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736288754, states[0] = -94.707165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751784859, states[0] = -94.703319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767560199, states[0] = 5.613478, states[40]= 0.004837
Saving checkpoint... 
Iteration: 778707961, states[0] = -94.586962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794680281, states[0] = -94.514657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810665205, states[0] = -93.851629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826218981, states[0] = -94.609260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841801137, states[0] = -94.718334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857311420, states[0] = -94.726655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872517227, states[0] = 21.155030, states[40]= 0.013158
Saving checkpoint... 
Iteration: 888240524, states[0] = -94.646963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904028905, states[0] = 18.075476, states[40]= 0.006310
Saving checkpoint... 
Iteration: 919346374, states[0] = -94.749377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935343215, states[0] = -94.747613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951142307, states[0] = -68.950205, states[40]= 0.000001
Saving checkpoint... 
Iteration: 967311576, states[0] = -94.726701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983151060, states[0] = -81.332924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998877908, states[0] = -94.764199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014873654, states[0] = -94.762433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030919650, states[0] = -94.778123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046488944, states[0] = -94.791958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062101934, states[0] = -26.730735, states[40]= 0.000604
Saving checkpoint... 
Iteration: 1078156458, states[0] = -88.920847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094041470, states[0] = 13.557213, states[40]= 0.005264
Saving checkpoint... 
Iteration: 1110038320, states[0] = 14.770106, states[40]= 0.005412
Saving checkpoint... 
Iteration: 1125978488, states[0] = -94.790356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141635235, states[0] = -60.759878, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1157768998, states[0] = -94.685761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173371977, states[0] = -94.761614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189221868, states[0] = -94.614525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198123779, states[0] = -48.572000, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1214336088, states[0] = -94.743265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229964822, states[0] = -94.788012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245951432, states[0] = -94.785463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261837695, states[0] = -94.744196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277430253, states[0] = -94.780707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293206970, states[0] = -94.584506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304087745, states[0] = -12.887283, states[40]= 0.001831
Saving checkpoint... 
Iteration: 1320209278, states[0] = -94.589367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336044598, states[0] = 12.319225, states[40]= 0.005158
Saving checkpoint... 
Iteration: 1350270358, states[0] = -94.687224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365735596, states[0] = -94.638682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381441812, states[0] = -94.783339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397037759, states[0] = 14.981739, states[40]= 0.005443
Saving checkpoint... 
Iteration: 1412669802, states[0] = -94.320359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428471056, states[0] = -94.788953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443972025, states[0] = -94.789104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459849411, states[0] = -94.750648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475265645, states[0] = -94.681520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490734991, states[0] = -94.637593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506398131, states[0] = -37.979205, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1521569997, states[0] = -95.043270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537131538, states[0] = -95.012644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551945495, states[0] = 8.677178, states[40]= 0.005797
Saving checkpoint... 
Iteration: 1567568576, states[0] = -7.743933, states[40]= 0.003216
Saving checkpoint... 
Iteration: 1582924977, states[0] = -74.484335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598591439, states[0] = -94.961264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613804083, states[0] = -48.021988, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1629247472, states[0] = -95.059135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644779363, states[0] = -94.934943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660375786, states[0] = -94.925946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675843173, states[0] = 9.713020, states[40]= 0.005921
Saving checkpoint... 
Iteration: 1690845747, states[0] = 8.306978, states[40]= 0.005779
Saving checkpoint... 
Iteration: 1706081036, states[0] = -95.095012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721667188, states[0] = -95.082222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737208347, states[0] = -94.999979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752953605, states[0] = 3.682084, states[40]= 0.005334
Saving checkpoint... 
Iteration: 1768084279, states[0] = -94.947922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783698371, states[0] = -94.979973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799022663, states[0] = -95.025115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810984807, states[0] = -94.847100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826815846, states[0] = -94.766190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841737693, states[0] = -94.666074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857081256, states[0] = -7.662489, states[40]= 0.002899
Saving checkpoint... 
Iteration: 1872415754, states[0] = -94.786046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887859856, states[0] = -94.761680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903431202, states[0] = -94.784301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918681796, states[0] = -94.523361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934376140, states[0] = -94.764330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949670790, states[0] = -94.368593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965189057, states[0] = -94.543616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980427000, states[0] = -94.779756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995590353, states[0] = -15.403031, states[40]= 0.001440
Saving checkpoint... 
Iteration: 2010262906, states[0] = -94.677874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024928487, states[0] = -94.779813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035646401, states[0] = -74.375440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051284088, states[0] = -94.701653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067015942, states[0] = 21.419421, states[40]= 0.015841
Saving checkpoint... 
Iteration: 2082907719, states[0] = -94.773932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098489249, states[0] = -94.791246, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.668550
 - CaMKt in component CaMK (millimolar): 0.006980
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.675957
 - nass in component intracellular_ions (millimolar): 6.676017
 - ki in component intracellular_ions (millimolar): 145.299165
 - kss in component intracellular_ions (millimolar): 145.299147
 - cansr in component intracellular_ions (millimolar): 1.321901
 - cajsr in component intracellular_ions (millimolar): 1.284631
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003705
 - hf in component INa (dimensionless): 0.875893
 - hs in component INa (dimensionless): 0.875888
 - j in component INa (dimensionless): 0.875855
 - hsp in component INa (dimensionless): 0.718133
 - jp in component INa (dimensionless): 0.875834
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.704701
 - hLp in component INaL (dimensionless): 0.447960
 - a in component Ito (dimensionless): 0.000633
 - iF in component Ito (dimensionless): 0.999864
 - iS in component Ito (dimensionless): 0.625547
 - ap in component Ito (dimensionless): 0.000323
 - iFp in component Ito (dimensionless): 0.999864
 - iSp in component Ito (dimensionless): 0.701235
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940569
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999902
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001647
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326710
 - xs1 in component IKs (dimensionless): 0.229252
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997398
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:19:39 (26908): called boinc_finish(0)

</stderr_txt>
]]>