𝕏

Task 55451101

Name HuVeMOp_20240630155542641650_ORdGradInc_k_25-Pueyo_APDR-conf_253_0
Workunit 26331615
Created 30 Jun 2024, 13:55:51 UTC
Sent 30 Jun 2024, 15:00:26 UTC
Report deadline 4 Jul 2024, 0:36:26 UTC
Received 3 Jul 2024, 10:01:51 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226324
Run time 2 hours 48 min 3 sec
CPU time 2 hours 30 min 54 sec
Validate state Valid
Credit 65.17
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630155542641650_ORdGradInc_k_25-Pueyo_APDR-conf_253.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630155542641650_ORdGradInc_k_25-Pueyo_APDR-conf_253_0_r1216389938_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630155542641650_ORdGradInc_k_25-Pueyo_APDR-conf_253_0_r1216389938_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 96.790248
     * GNaL_b in INaL: 0.005521
     * Gto_b in Ito: 0.093991
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032877
     * GKs_b in IKs: 0.001888
     * GK1_b in IK1: 0.180043
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 67.058056
     * GKb_b in IKb: 0.003671
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.027118
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14286308, states[0] = -94.995145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27619420, states[0] = -39.746753, states[40]= 0.000138
Saving checkpoint... 
Iteration: 40667896, states[0] = -94.594877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53792734, states[0] = -94.966378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67199974, states[0] = -94.839653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80223329, states[0] = -94.879529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94520030, states[0] = 20.487437, states[40]= 0.008531
Saving checkpoint... 
Iteration: 108419347, states[0] = -95.016040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121603508, states[0] = -22.997381, states[40]= 0.000806
Saving checkpoint... 
Iteration: 134454300, states[0] = -95.022020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148060367, states[0] = 7.361639, states[40]= 0.004714
Saving checkpoint... 
Iteration: 162093481, states[0] = -13.494483, states[40]= 0.001685
Saving checkpoint... 
Iteration: 176682152, states[0] = -94.793547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191311557, states[0] = -94.969592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204409991, states[0] = -95.011704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218276413, states[0] = -94.941464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231836897, states[0] = -94.984336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245534190, states[0] = 17.033871, states[40]= 0.005164
Saving checkpoint... 
Iteration: 260484585, states[0] = -95.025524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273864263, states[0] = -94.996732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286415495, states[0] = -95.012919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300041484, states[0] = 14.608896, states[40]= 0.004872
Saving checkpoint... 
Iteration: 313168419, states[0] = -94.523478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326551490, states[0] = 10.937973, states[40]= 0.004762
Saving checkpoint... 
Iteration: 339668463, states[0] = -94.527156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353655787, states[0] = -84.745390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366083265, states[0] = -4.929299, states[40]= 0.003388
Saving checkpoint... 
Iteration: 379392643, states[0] = -95.006555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392302667, states[0] = -94.963072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405991362, states[0] = -95.026233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418785859, states[0] = -94.949752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431596117, states[0] = -15.924189, states[40]= 0.001343
Saving checkpoint... 
Iteration: 444286306, states[0] = -94.950115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457657117, states[0] = -87.082025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470285896, states[0] = -94.949742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483415334, states[0] = -95.012710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496060279, states[0] = 7.413938, states[40]= 0.004715
Saving checkpoint... 
Iteration: 509851635, states[0] = -94.991177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523077337, states[0] = -1.018477, states[40]= 0.004070
Saving checkpoint... 
Iteration: 536612301, states[0] = -31.234316, states[40]= 0.000422
Saving checkpoint... 
Iteration: 549342340, states[0] = -94.986773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561635752, states[0] = -55.355867, states[40]= 0.000012
Saving checkpoint... 
Iteration: 574999898, states[0] = -95.027092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588459173, states[0] = -95.021520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601806845, states[0] = -94.965874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615051983, states[0] = 10.748921, states[40]= 0.004761
Saving checkpoint... 
Iteration: 628245473, states[0] = -94.906538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641274939, states[0] = -94.939633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653851336, states[0] = -94.990926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666665124, states[0] = -94.016140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679382092, states[0] = -95.002929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692426313, states[0] = -95.015120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705431609, states[0] = -95.016262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718130073, states[0] = -49.091336, states[40]= 0.000034
Saving checkpoint... 
Iteration: 731331072, states[0] = -94.980773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744561250, states[0] = 7.001304, states[40]= 0.004704
Saving checkpoint... 
Iteration: 757667745, states[0] = -94.458598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771303626, states[0] = -94.963459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786761737, states[0] = -94.925916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800263770, states[0] = -94.928122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813061563, states[0] = 6.867094, states[40]= 0.004701
Saving checkpoint... 
Iteration: 826342683, states[0] = -94.986719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839507532, states[0] = 22.804499, states[40]= 0.095886
Saving checkpoint... 
Iteration: 852588107, states[0] = -8.715790, states[40]= 0.002592
Saving checkpoint... 
Iteration: 865348270, states[0] = -94.989353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878338765, states[0] = -94.984720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891163915, states[0] = -93.647203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905134500, states[0] = -53.949788, states[40]= 0.000016
Saving checkpoint... 
Iteration: 917617190, states[0] = -35.931202, states[40]= 0.000239
Saving checkpoint... 
Iteration: 931045133, states[0] = 13.306361, states[40]= 0.004809
Saving checkpoint... 
Iteration: 943957697, states[0] = -95.020990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957423898, states[0] = -95.014362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970518764, states[0] = 20.717180, states[40]= 0.009701
Saving checkpoint... 
Iteration: 983433130, states[0] = -95.016359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996386946, states[0] = -95.004272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010072329, states[0] = 1.787980, states[40]= 0.004403
Saving checkpoint... 
Iteration: 1024122981, states[0] = -41.664136, states[40]= 0.000106
Saving checkpoint... 
Iteration: 1037573855, states[0] = 0.971809, states[40]= 0.004321
Saving checkpoint... 
Iteration: 1050639114, states[0] = -59.227060, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1064176128, states[0] = -94.764784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076664847, states[0] = -93.943081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089548083, states[0] = 12.223222, states[40]= 0.004781
Saving checkpoint... 
Iteration: 1103054516, states[0] = 9.762696, states[40]= 0.004751
Saving checkpoint... 
Iteration: 1115605555, states[0] = -24.839052, states[40]= 0.000722
Saving checkpoint... 
Iteration: 1129310170, states[0] = -94.967726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142775870, states[0] = -94.940119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155475999, states[0] = -95.023622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168332556, states[0] = -94.981228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181331010, states[0] = -94.980376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194596919, states[0] = -16.678349, states[40]= 0.001256
Saving checkpoint... 
Iteration: 1208028000, states[0] = 18.811559, states[40]= 0.005756
Saving checkpoint... 
Iteration: 1220741298, states[0] = -94.900503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233788178, states[0] = -94.951065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247429749, states[0] = -95.015427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260946497, states[0] = -95.018768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274357895, states[0] = -94.993293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287377937, states[0] = -95.001012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301333057, states[0] = -94.981391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314633746, states[0] = -53.110152, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1327779047, states[0] = -94.942948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341370611, states[0] = -94.998312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354349041, states[0] = -94.989315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367737736, states[0] = -94.895454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381475709, states[0] = -95.023400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394548580, states[0] = 12.038199, states[40]= 0.004777
Saving checkpoint... 
Iteration: 1407806992, states[0] = -94.965326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420927990, states[0] = -95.014904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433889687, states[0] = -95.004791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447004383, states[0] = 28.127991, states[40]= 0.175825
Saving checkpoint... 
Iteration: 1460103576, states[0] = -22.969980, states[40]= 0.000807
Saving checkpoint... 
Iteration: 1472945422, states[0] = -95.018397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486258224, states[0] = -94.921409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499683662, states[0] = -94.796265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512702237, states[0] = -38.268307, states[40]= 0.000170
Saving checkpoint... 
Iteration: 1525741197, states[0] = -95.197883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539272584, states[0] = -95.237692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552052754, states[0] = -95.024236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565543045, states[0] = -94.493514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578336196, states[0] = 14.210149, states[40]= 0.005985
Saving checkpoint... 
Iteration: 1591227737, states[0] = 17.683587, states[40]= 0.006851
Saving checkpoint... 
Iteration: 1604263964, states[0] = -95.083269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617227087, states[0] = -95.206706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630680006, states[0] = -95.124025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643634870, states[0] = -95.217554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656680046, states[0] = -16.529105, states[40]= 0.001430
Saving checkpoint... 
Iteration: 1669344754, states[0] = -94.791973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1682087179, states[0] = -95.266814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1695773361, states[0] = -95.109302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709843587, states[0] = -94.668065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722750871, states[0] = -95.022548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735206090, states[0] = 25.461318, states[40]= 0.124769
Saving checkpoint... 
Iteration: 1748546527, states[0] = -94.910045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760563859, states[0] = -95.085125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773509631, states[0] = -95.182133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786428361, states[0] = -95.209724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799409728, states[0] = 22.650826, states[40]= 0.055446
Saving checkpoint... 
Iteration: 1812243693, states[0] = -94.940872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824984378, states[0] = -95.052750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837412381, states[0] = -95.030836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850336320, states[0] = -94.996331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865684608, states[0] = -94.807168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878781434, states[0] = -94.950552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892218773, states[0] = -94.869608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906051617, states[0] = 10.837092, states[40]= 0.004762
Saving checkpoint... 
Iteration: 1919109167, states[0] = -28.374089, states[40]= 0.000557
Saving checkpoint... 
Iteration: 1932432156, states[0] = -95.016518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945489396, states[0] = -95.025496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958321794, states[0] = -94.974944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971173896, states[0] = -94.740226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984150398, states[0] = -74.857850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996704331, states[0] = -94.839520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009321015, states[0] = -94.973993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021941323, states[0] = -95.017183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034341946, states[0] = -94.985364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047164027, states[0] = -93.686988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060090189, states[0] = -10.502272, states[40]= 0.002224
Saving checkpoint... 
Iteration: 2072909782, states[0] = -95.009964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085715790, states[0] = -94.860276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098718587, states[0] = -94.865076, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.901683
 - CaMKt in component CaMK (millimolar): 0.007410
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.739196
 - nass in component intracellular_ions (millimolar): 6.739257
 - ki in component intracellular_ions (millimolar): 145.230652
 - kss in component intracellular_ions (millimolar): 145.230633
 - cansr in component intracellular_ions (millimolar): 1.339490
 - cajsr in component intracellular_ions (millimolar): 1.301057
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003619
 - hf in component INa (dimensionless): 0.879998
 - hs in component INa (dimensionless): 0.879993
 - j in component INa (dimensionless): 0.879965
 - hsp in component INa (dimensionless): 0.725826
 - jp in component INa (dimensionless): 0.879947
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710245
 - hLp in component INaL (dimensionless): 0.453058
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621929
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697310
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936695
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001701
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.317428
 - xs1 in component IKs (dimensionless): 0.240629
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:01:50 (35142): called boinc_finish(0)

</stderr_txt>
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