𝕏

Task 55450065

Name HuVeMOp_20240630154541927258_ORdGradInc_k_25-Pueyo_APDR-conf_113_1
Workunit 26331103
Created 30 Jun 2024, 13:45:47 UTC
Sent 30 Jun 2024, 14:55:05 UTC
Report deadline 4 Jul 2024, 0:31:05 UTC
Received 1 Jul 2024, 14:04:24 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236597
Run time 2 hours 18 min 33 sec
CPU time 2 hours 15 min 51 sec
Validate state Valid
Credit 60.82
Device peak FLOPS 4.22 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.90 MB
Peak swap size 3.82 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630154541927258_ORdGradInc_k_25-Pueyo_APDR-conf_113.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630154541927258_ORdGradInc_k_25-Pueyo_APDR-conf_113_1_r1415364838_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630154541927258_ORdGradInc_k_25-Pueyo_APDR-conf_113_1_r1415364838_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.916579
     * GNaL_b in INaL: 0.006495
     * Gto_b in Ito: 0.095420
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031676
     * GKs_b in IKs: 0.001772
     * GK1_b in IK1: 0.178028
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 70.365165
     * GKb_b in IKb: 0.003771
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.021171
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 18094758, states[0] = -14.184491, states[40]= 0.001573
Saving checkpoint... 
Iteration: 35841523, states[0] = -95.121342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54669080, states[0] = -94.237530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72669329, states[0] = -94.151987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90502913, states[0] = 36.428496, states[40]= 0.153323
Saving checkpoint... 
Iteration: 108247668, states[0] = -95.014991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125466728, states[0] = -95.130875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143226406, states[0] = -94.981685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161266664, states[0] = -95.034973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178698603, states[0] = -94.929878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196507562, states[0] = 23.088543, states[40]= 0.097305
Saving checkpoint... 
Iteration: 214816301, states[0] = -95.076554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232896278, states[0] = -95.113055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250732322, states[0] = -94.989786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269804833, states[0] = -95.068433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287472577, states[0] = -95.129713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304883313, states[0] = -95.108709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321965397, states[0] = -95.128552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338919246, states[0] = -95.119229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355582191, states[0] = -2.022677, states[40]= 0.003908
Saving checkpoint... 
Iteration: 372600968, states[0] = -16.799847, states[40]= 0.001248
Saving checkpoint... 
Iteration: 389479754, states[0] = -95.130670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407212597, states[0] = -94.956418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425109795, states[0] = -24.779053, states[40]= 0.000764
Saving checkpoint... 
Iteration: 443938888, states[0] = -95.123593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462108559, states[0] = -23.662017, states[40]= 0.000812
Saving checkpoint... 
Iteration: 479585246, states[0] = -3.981316, states[40]= 0.003562
Saving checkpoint... 
Iteration: 497042241, states[0] = 15.096107, states[40]= 0.004894
Saving checkpoint... 
Iteration: 515573009, states[0] = 2.964176, states[40]= 0.004505
Saving checkpoint... 
Iteration: 534973309, states[0] = -95.129617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554629399, states[0] = -43.188695, states[40]= 0.000090
Saving checkpoint... 
Iteration: 572930010, states[0] = -95.121583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590563596, states[0] = 7.178201, states[40]= 0.004724
Saving checkpoint... 
Iteration: 607728938, states[0] = -94.984191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624482973, states[0] = -95.130937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640601563, states[0] = -17.336931, states[40]= 0.001195
Saving checkpoint... 
Iteration: 656527830, states[0] = 19.344786, states[40]= 0.005894
Saving checkpoint... 
Iteration: 672373820, states[0] = -95.104987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688240933, states[0] = -95.002041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704420819, states[0] = -95.119331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720359197, states[0] = -95.099030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736153232, states[0] = -71.411935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 752005291, states[0] = 26.121430, states[40]= 0.156585
Saving checkpoint... 
Iteration: 768104460, states[0] = -19.957416, states[40]= 0.000993
Saving checkpoint... 
Iteration: 784310084, states[0] = -95.071768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800513572, states[0] = 21.593143, states[40]= 0.023143
Saving checkpoint... 
Iteration: 816897866, states[0] = -95.113006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833642864, states[0] = -57.800899, states[40]= 0.000009
Saving checkpoint... 
Iteration: 849780531, states[0] = -95.047731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866104496, states[0] = -19.989923, states[40]= 0.000991
Saving checkpoint... 
Iteration: 882352078, states[0] = -95.095713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898207262, states[0] = -94.946030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914306733, states[0] = -95.069291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930424431, states[0] = -95.120024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946569058, states[0] = 4.815465, states[40]= 0.004628
Saving checkpoint... 
Iteration: 962518676, states[0] = 21.063061, states[40]= 0.010125
Saving checkpoint... 
Iteration: 978477892, states[0] = -95.129950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994329388, states[0] = -95.083869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010399856, states[0] = -95.113452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026244102, states[0] = -95.006165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042444179, states[0] = -95.124200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058263457, states[0] = -95.030062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073928147, states[0] = -95.120776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090316457, states[0] = -95.075841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106178479, states[0] = -94.844407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122806000, states[0] = -95.068600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138714972, states[0] = -94.960167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154342766, states[0] = -95.090987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170500190, states[0] = -71.814957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186335392, states[0] = -95.087087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202292064, states[0] = -95.057676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218331862, states[0] = -95.085107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234276231, states[0] = -95.043309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250411041, states[0] = -95.116414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266294448, states[0] = -95.059594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282240813, states[0] = -95.001412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298155745, states[0] = -75.552598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314255782, states[0] = -95.020940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330079232, states[0] = -0.285524, states[40]= 0.004164
Saving checkpoint... 
Iteration: 1345900489, states[0] = -95.113381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362077937, states[0] = 0.431549, states[40]= 0.004254
Saving checkpoint... 
Iteration: 1377885296, states[0] = -95.108552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393566205, states[0] = 6.074630, states[40]= 0.004687
Saving checkpoint... 
Iteration: 1409635152, states[0] = -49.202670, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1425427551, states[0] = -95.120370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441150250, states[0] = -67.042367, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1456918187, states[0] = -95.118102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472697721, states[0] = -94.926653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488491572, states[0] = -95.131408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504304428, states[0] = -35.579280, states[40]= 0.000244
Saving checkpoint... 
Iteration: 1520299745, states[0] = -95.236673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535997943, states[0] = -95.361145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551830264, states[0] = -95.305970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567607019, states[0] = -41.732389, states[40]= 0.000113
Saving checkpoint... 
Iteration: 1583444373, states[0] = 11.076774, states[40]= 0.005683
Saving checkpoint... 
Iteration: 1599488003, states[0] = -95.244273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615600337, states[0] = -34.833076, states[40]= 0.000287
Saving checkpoint... 
Iteration: 1631344774, states[0] = -95.335724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647217029, states[0] = -95.299309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662926690, states[0] = 18.465024, states[40]= 0.007190
Saving checkpoint... 
Iteration: 1678812093, states[0] = 22.282888, states[40]= 0.033501
Saving checkpoint... 
Iteration: 1694631796, states[0] = -95.320708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710633093, states[0] = 16.028826, states[40]= 0.006302
Saving checkpoint... 
Iteration: 1726387583, states[0] = -95.245971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742289588, states[0] = -95.250210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758137404, states[0] = -87.005057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773987087, states[0] = -20.967499, states[40]= 0.000989
Saving checkpoint... 
Iteration: 1789917292, states[0] = -54.573856, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1805770269, states[0] = -95.081330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821583848, states[0] = -4.532761, states[40]= 0.003500
Saving checkpoint... 
Iteration: 1837338240, states[0] = -95.108883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853166241, states[0] = -93.071835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868928548, states[0] = -95.128289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872212012, states[0] = -94.961670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887842918, states[0] = -95.095056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903589853, states[0] = -7.449118, states[40]= 0.002850
Saving checkpoint... 
Iteration: 1919202479, states[0] = -94.937696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934920414, states[0] = -95.119353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950617051, states[0] = -31.431695, states[40]= 0.000440
Saving checkpoint... 
Iteration: 1966278398, states[0] = -95.045228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981974688, states[0] = -95.128920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997730782, states[0] = -94.986116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013555160, states[0] = 10.501097, states[40]= 0.004779
Saving checkpoint... 
Iteration: 2029335716, states[0] = -95.086610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045523046, states[0] = 20.369320, states[40]= 0.007098
Saving checkpoint... 
Iteration: 2062493691, states[0] = -95.131185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078878962, states[0] = -95.105742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095134466, states[0] = -48.467014, states[40]= 0.000040
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.007776
 - CaMKt in component CaMK (millimolar): 0.007481
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.596485
 - nass in component intracellular_ions (millimolar): 6.596547
 - ki in component intracellular_ions (millimolar): 145.373421
 - kss in component intracellular_ions (millimolar): 145.373400
 - cansr in component intracellular_ions (millimolar): 1.341127
 - cajsr in component intracellular_ions (millimolar): 1.302183
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003580
 - hf in component INa (dimensionless): 0.881827
 - hs in component INa (dimensionless): 0.881822
 - j in component INa (dimensionless): 0.881793
 - hsp in component INa (dimensionless): 0.729280
 - jp in component INa (dimensionless): 0.881774
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711778
 - hLp in component INaL (dimensionless): 0.452484
 - a in component Ito (dimensionless): 0.000619
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.617301
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.691808
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932855
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999876
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001712
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329715
 - xs1 in component IKs (dimensionless): 0.249211
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997309
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:04:11 (100146): called boinc_finish(0)

</stderr_txt>
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