𝕏

Task 55449825

Name HuVeMOp_20240630153550922303_ORdGradInc_k_25-Pueyo_APDR-conf_226_1
Workunit 26331004
Created 30 Jun 2024, 13:35:59 UTC
Sent 30 Jun 2024, 14:51:50 UTC
Report deadline 4 Jul 2024, 0:27:50 UTC
Received 30 Jun 2024, 19:37:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215450
Run time 1 hours 14 min 27 sec
CPU time 1 hours 6 min 49 sec
Validate state Valid
Credit 59.15
Device peak FLOPS 5.18 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.37 MB
Peak swap size 5.29 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.16.11</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630153550922303_ORdGradInc_k_25-Pueyo_APDR-conf_226.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630153550922303_ORdGradInc_k_25-Pueyo_APDR-conf_226_1_r1121375722_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630153550922303_ORdGradInc_k_25-Pueyo_APDR-conf_226_1_r1121375722_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.874668
     * GNaL_b in INaL: 0.005038
     * Gto_b in Ito: 0.088704
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032368
     * GKs_b in IKs: 0.001857
     * GK1_b in IK1: 0.165058
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 74.644582
     * GKb_b in IKb: 0.003924
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026465
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 18354156, states[0] = -95.139090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36563939, states[0] = 4.376270, states[40]= 0.004658
Saving checkpoint... 
Iteration: 54416042, states[0] = -95.096881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72467470, states[0] = -95.096169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91337777, states[0] = -95.048191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110433451, states[0] = -95.079074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129207783, states[0] = -94.894839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147174466, states[0] = -94.773392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165307023, states[0] = -95.020552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183492912, states[0] = -95.084940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201671186, states[0] = -94.674427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219569172, states[0] = 2.897532, states[40]= 0.004533
Saving checkpoint... 
Iteration: 237584176, states[0] = -6.388282, states[40]= 0.003102
Saving checkpoint... 
Iteration: 255848379, states[0] = -95.044972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274225574, states[0] = -94.924918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292123929, states[0] = -44.007946, states[40]= 0.000072
Saving checkpoint... 
Iteration: 310913279, states[0] = -95.069062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329514769, states[0] = 21.522645, states[40]= 0.018005
Saving checkpoint... 
Iteration: 348082044, states[0] = -4.785894, states[40]= 0.003433
Saving checkpoint... 
Iteration: 366517516, states[0] = 21.129276, states[40]= 0.011697
Saving checkpoint... 
Iteration: 384847481, states[0] = -95.044363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403411866, states[0] = -95.068597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421550452, states[0] = 11.042379, states[40]= 0.004851
Saving checkpoint... 
Iteration: 439739519, states[0] = -94.946989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457849195, states[0] = -95.045162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476046260, states[0] = 12.651251, states[40]= 0.004899
Saving checkpoint... 
Iteration: 493483713, states[0] = -95.082920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511656572, states[0] = -86.217943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529986016, states[0] = -95.083213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547894568, states[0] = -95.063338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565868341, states[0] = -95.053740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583972420, states[0] = -95.081178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601806506, states[0] = -95.018884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619785235, states[0] = -95.001071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637724089, states[0] = -94.922055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655735026, states[0] = -94.939998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674342944, states[0] = -95.041813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692332791, states[0] = -95.036195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711138058, states[0] = -59.265252, states[40]= 0.000006
Saving checkpoint... 
Iteration: 729263687, states[0] = -94.978577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747799141, states[0] = -95.013037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765817434, states[0] = -95.026536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784237231, states[0] = -94.943291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802314141, states[0] = -95.024253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820607114, states[0] = -27.497116, states[40]= 0.000587
Saving checkpoint... 
Iteration: 838412256, states[0] = -95.068378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856909678, states[0] = -95.067651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874974512, states[0] = -95.081285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893144573, states[0] = -67.157864, states[40]= 0.000002
Saving checkpoint... 
Iteration: 911002773, states[0] = 36.972042, states[40]= 0.148052
Saving checkpoint... 
Iteration: 928816117, states[0] = -95.025521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946627102, states[0] = -47.314190, states[40]= 0.000043
Saving checkpoint... 
Iteration: 965162808, states[0] = -92.951872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983645750, states[0] = -68.729651, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1001859376, states[0] = -95.049556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016252931, states[0] = -94.965176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032010681, states[0] = 22.142883, states[40]= 0.043514
Saving checkpoint... 
Iteration: 1046284878, states[0] = -95.000419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059742807, states[0] = -94.951327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077142657, states[0] = -64.714929, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1093130841, states[0] = -51.300373, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1110576023, states[0] = -0.831610, states[40]= 0.004120
Saving checkpoint... 
Iteration: 1125766653, states[0] = -94.981666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143157159, states[0] = -87.140977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161513648, states[0] = 21.671401, states[40]= 0.022366
Saving checkpoint... 
Iteration: 1180486129, states[0] = -95.082744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199559585, states[0] = 7.321381, states[40]= 0.004767
Saving checkpoint... 
Iteration: 1218034540, states[0] = 16.836295, states[40]= 0.005312
Saving checkpoint... 
Iteration: 1235995630, states[0] = -95.083951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253379057, states[0] = -95.057430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269765432, states[0] = -94.980177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287024009, states[0] = 19.855554, states[40]= 0.006876
Saving checkpoint... 
Iteration: 1304588384, states[0] = -9.852490, states[40]= 0.002366
Saving checkpoint... 
Iteration: 1321753673, states[0] = -94.965904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338837901, states[0] = -95.038602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354740392, states[0] = -94.947593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369757239, states[0] = -94.970368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385364966, states[0] = -95.051714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403149949, states[0] = -74.918237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421025518, states[0] = 19.487470, states[40]= 0.006462
Saving checkpoint... 
Iteration: 1440092748, states[0] = -13.802994, states[40]= 0.001643
Saving checkpoint... 
Iteration: 1458926055, states[0] = -95.071458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477376618, states[0] = -95.056343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481530842, states[0] = 18.005146, states[40]= 0.005622
Saving checkpoint... 
Iteration: 1482343048, states[0] = -95.041264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482376027, states[0] = -95.056114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483327569, states[0] = -95.032498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504217884, states[0] = 21.390493, states[40]= 0.013381
Saving checkpoint... 
Iteration: 1524247287, states[0] = -95.280910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543443836, states[0] = -95.292089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562488424, states[0] = -26.209426, states[40]= 0.000643
Saving checkpoint... 
Iteration: 1581345517, states[0] = 9.510317, states[40]= 0.005643
Saving checkpoint... 
Iteration: 1600585286, states[0] = -23.099664, states[40]= 0.000818
Saving checkpoint... 
Iteration: 1620026524, states[0] = 18.111099, states[40]= 0.007332
Saving checkpoint... 
Iteration: 1639639755, states[0] = -93.416418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659438618, states[0] = -92.751617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679401871, states[0] = 44.364505, states[40]= 0.079369
Saving checkpoint... 
Iteration: 1698490300, states[0] = -95.223273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1718366969, states[0] = -95.334777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737964758, states[0] = -2.392008, states[40]= 0.004367
Saving checkpoint... 
Iteration: 1757360997, states[0] = -95.329089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776486129, states[0] = -95.214084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1795417879, states[0] = -95.274662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814494909, states[0] = -95.127949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834088637, states[0] = -11.347253, states[40]= 0.002085
Saving checkpoint... 
Iteration: 1853884437, states[0] = -95.073026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873722614, states[0] = -94.926468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892885483, states[0] = -95.063590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912286014, states[0] = -95.003233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931758736, states[0] = -94.973111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951128703, states[0] = -49.063344, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1970523566, states[0] = 19.954617, states[40]= 0.007021
Saving checkpoint... 
Iteration: 1990076900, states[0] = -1.368783, states[40]= 0.004042
Saving checkpoint... 
Iteration: 2009394620, states[0] = -95.062332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028674173, states[0] = -94.763139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047939850, states[0] = -95.074111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067150584, states[0] = -75.946025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087600750, states[0] = -21.414748, states[40]= 0.000879
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.959663
 - CaMKt in component CaMK (millimolar): 0.007216
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.444188
 - nass in component intracellular_ions (millimolar): 6.444249
 - ki in component intracellular_ions (millimolar): 145.528651
 - kss in component intracellular_ions (millimolar): 145.528632
 - cansr in component intracellular_ions (millimolar): 1.328375
 - cajsr in component intracellular_ions (millimolar): 1.290188
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003597
 - hf in component INa (dimensionless): 0.881000
 - hs in component INa (dimensionless): 0.880996
 - j in component INa (dimensionless): 0.880966
 - hsp in component INa (dimensionless): 0.727715
 - jp in component INa (dimensionless): 0.880946
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711716
 - hLp in component INaL (dimensionless): 0.454577
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.623139
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.698699
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937320
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999893
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001666
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.318201
 - xs1 in component IKs (dimensionless): 0.238245
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997322
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:09:46 (1984): called boinc_finish(0)

</stderr_txt>
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