𝕏

Task 55448692

Name HuVeMOp_20240630152049369056_ORdGradInc_k_25-Pueyo_APDR-conf_126_1
Workunit 26330451
Created 30 Jun 2024, 13:20:58 UTC
Sent 30 Jun 2024, 14:47:48 UTC
Report deadline 4 Jul 2024, 0:23:48 UTC
Received 30 Jun 2024, 17:12:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 24 min 20 sec
CPU time 2 hours 22 min 34 sec
Validate state Valid
Credit 58.42
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630152049369056_ORdGradInc_k_25-Pueyo_APDR-conf_126.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630152049369056_ORdGradInc_k_25-Pueyo_APDR-conf_126_1_r311356933_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630152049369056_ORdGradInc_k_25-Pueyo_APDR-conf_126_1_r311356933_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.971066
     * GNaL_b in INaL: 0.004462
     * Gto_b in Ito: 0.087945
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032285
     * GKs_b in IKs: 0.001764
     * GK1_b in IK1: 0.167196
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 68.752877
     * GKb_b in IKb: 0.003711
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051113
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15047424, states[0] = 10.112677, states[40]= 0.004952
Saving checkpoint... 
Iteration: 30066696, states[0] = 1.747480, states[40]= 0.004445
Saving checkpoint... 
Iteration: 44960019, states[0] = -95.005114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59996223, states[0] = -95.000961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74854404, states[0] = -94.963980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89775395, states[0] = -94.912045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104924535, states[0] = -94.978975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119826295, states[0] = -94.943712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134835515, states[0] = -94.947479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149774609, states[0] = -94.906059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165033686, states[0] = 16.263896, states[40]= 0.005654
Saving checkpoint... 
Iteration: 180501533, states[0] = 47.808290, states[40]= 0.058279
Saving checkpoint... 
Iteration: 195964882, states[0] = -94.982205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211111015, states[0] = -34.734790, states[40]= 0.000245
Saving checkpoint... 
Iteration: 226177059, states[0] = -94.753808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241188337, states[0] = -94.782149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256060659, states[0] = 5.598969, states[40]= 0.004716
Saving checkpoint... 
Iteration: 270845343, states[0] = -94.950320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285949310, states[0] = -94.979498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300885284, states[0] = -94.964965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315984272, states[0] = -94.984386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330921360, states[0] = -94.974172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346059591, states[0] = 6.080207, states[40]= 0.004741
Saving checkpoint... 
Iteration: 361202007, states[0] = -94.808326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376459079, states[0] = -94.980966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391469495, states[0] = -94.982451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406603313, states[0] = -27.119719, states[40]= 0.000562
Saving checkpoint... 
Iteration: 422067811, states[0] = 2.151509, states[40]= 0.004466
Saving checkpoint... 
Iteration: 437415052, states[0] = -94.972705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452819906, states[0] = -94.937390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468237863, states[0] = -94.864584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483738332, states[0] = -94.865189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499250922, states[0] = -94.880623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514597104, states[0] = -21.015912, states[40]= 0.000874
Saving checkpoint... 
Iteration: 529653483, states[0] = -87.352245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545148721, states[0] = -79.220265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560604867, states[0] = -28.648994, states[40]= 0.000490
Saving checkpoint... 
Iteration: 575944342, states[0] = -94.978459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591030012, states[0] = 17.473891, states[40]= 0.006083
Saving checkpoint... 
Iteration: 606245021, states[0] = -94.873567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621259365, states[0] = -94.889834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636335178, states[0] = -94.945333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651492067, states[0] = -94.985062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666560071, states[0] = 5.865449, states[40]= 0.004730
Saving checkpoint... 
Iteration: 681395286, states[0] = -94.967600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696267035, states[0] = -94.897548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710967284, states[0] = -94.981949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725486108, states[0] = -94.984342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740232015, states[0] = -94.856499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754838145, states[0] = -94.946690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769359381, states[0] = -94.955794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783866338, states[0] = -94.958387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798484604, states[0] = -94.984121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813090646, states[0] = -14.698499, states[40]= 0.001502
Saving checkpoint... 
Iteration: 827843295, states[0] = -94.949030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842686521, states[0] = -94.777960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857358377, states[0] = -94.955350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872023477, states[0] = 19.325965, states[40]= 0.007674
Saving checkpoint... 
Iteration: 886750446, states[0] = -94.879836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901326974, states[0] = -94.940993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915987637, states[0] = -94.984402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930593100, states[0] = -17.083829, states[40]= 0.001202
Saving checkpoint... 
Iteration: 945592580, states[0] = -16.575654, states[40]= 0.001259
Saving checkpoint... 
Iteration: 960670792, states[0] = -94.702393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975537476, states[0] = 14.942638, states[40]= 0.005360
Saving checkpoint... 
Iteration: 990499813, states[0] = -94.985674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005662555, states[0] = -94.121898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020625763, states[0] = -49.911041, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1035529494, states[0] = 17.634963, states[40]= 0.006160
Saving checkpoint... 
Iteration: 1050509291, states[0] = 22.438154, states[40]= 0.062499
Saving checkpoint... 
Iteration: 1065585094, states[0] = -9.548619, states[40]= 0.002423
Saving checkpoint... 
Iteration: 1080721366, states[0] = -94.840630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095743368, states[0] = -94.871229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110842110, states[0] = -94.948318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125810913, states[0] = -94.931629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140881371, states[0] = -94.963232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155919853, states[0] = -94.973334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170899021, states[0] = -94.968308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185995631, states[0] = -94.985119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200847486, states[0] = -94.950656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215796726, states[0] = -94.922097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230689516, states[0] = -94.783841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245558039, states[0] = 6.765970, states[40]= 0.004774
Saving checkpoint... 
Iteration: 1260637612, states[0] = -63.173267, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1275594651, states[0] = -18.604215, states[40]= 0.001053
Saving checkpoint... 
Iteration: 1290530654, states[0] = 17.271505, states[40]= 0.005994
Saving checkpoint... 
Iteration: 1305635121, states[0] = -60.239539, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1320491176, states[0] = -94.984553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335336459, states[0] = -94.945525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350224692, states[0] = -94.845531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364910080, states[0] = -94.970974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379611621, states[0] = -35.324531, states[40]= 0.000227
Saving checkpoint... 
Iteration: 1394544864, states[0] = 12.165167, states[40]= 0.005035
Saving checkpoint... 
Iteration: 1409502958, states[0] = 36.733999, states[40]= 0.128294
Saving checkpoint... 
Iteration: 1424501710, states[0] = 46.616006, states[40]= 0.068469
Saving checkpoint... 
Iteration: 1439380816, states[0] = -94.962875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454309847, states[0] = -94.930761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469209833, states[0] = -94.821543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484638025, states[0] = -63.673363, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1499843329, states[0] = -94.948632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515083241, states[0] = -21.308783, states[40]= 0.000909
Saving checkpoint... 
Iteration: 1530305836, states[0] = 27.073206, states[40]= 0.114795
Saving checkpoint... 
Iteration: 1545573142, states[0] = -95.226283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560273988, states[0] = -95.233116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575555968, states[0] = -95.222230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591181260, states[0] = -95.244902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606578600, states[0] = -18.297242, states[40]= 0.001197
Saving checkpoint... 
Iteration: 1622042962, states[0] = -95.214439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637593295, states[0] = -95.145162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652679177, states[0] = -95.246725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667699524, states[0] = -95.259864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683039362, states[0] = 11.675552, states[40]= 0.006030
Saving checkpoint... 
Iteration: 1698480708, states[0] = -95.121240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1713908164, states[0] = 24.064820, states[40]= 0.078106
Saving checkpoint... 
Iteration: 1729388545, states[0] = -95.137010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744826103, states[0] = 17.659861, states[40]= 0.007900
Saving checkpoint... 
Iteration: 1760273480, states[0] = -95.105647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775766882, states[0] = -5.946969, states[40]= 0.003575
Saving checkpoint... 
Iteration: 1791281041, states[0] = -95.248443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1806656179, states[0] = -93.518918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821544272, states[0] = 11.823542, states[40]= 0.005055
Saving checkpoint... 
Iteration: 1836451588, states[0] = -95.001633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851388542, states[0] = -94.979627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866442319, states[0] = -94.986684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882000584, states[0] = 31.962514, states[40]= 0.001415
Saving checkpoint... 
Iteration: 1897646031, states[0] = -75.175764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912520945, states[0] = 19.903668, states[40]= 0.009027
Saving checkpoint... 
Iteration: 1928145011, states[0] = -73.304167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943314235, states[0] = -94.934103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1958488973, states[0] = -94.984498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973396538, states[0] = -94.967508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988973501, states[0] = -94.982215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004538462, states[0] = 14.581593, states[40]= 0.005301
Saving checkpoint... 
Iteration: 2019922545, states[0] = -94.973436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035121109, states[0] = -44.981076, states[40]= 0.000055
Saving checkpoint... 
Iteration: 2050674423, states[0] = -94.739367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066080092, states[0] = -5.459310, states[40]= 0.003286
Saving checkpoint... 
Iteration: 2081552781, states[0] = 8.998102, states[40]= 0.004866
Saving checkpoint... 
Iteration: 2096753153, states[0] = -94.882130, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.860846
 - CaMKt in component CaMK (millimolar): 0.006726
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.639254
 - nass in component intracellular_ions (millimolar): 6.639312
 - ki in component intracellular_ions (millimolar): 145.341639
 - kss in component intracellular_ions (millimolar): 145.341620
 - cansr in component intracellular_ions (millimolar): 1.297488
 - cajsr in component intracellular_ions (millimolar): 1.260263
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003634
 - hf in component INa (dimensionless): 0.879287
 - hs in component INa (dimensionless): 0.879283
 - j in component INa (dimensionless): 0.879258
 - hsp in component INa (dimensionless): 0.724491
 - jp in component INa (dimensionless): 0.879241
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710136
 - hLp in component INaL (dimensionless): 0.454696
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.626721
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.702969
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940822
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999902
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001543
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.319459
 - xs1 in component IKs (dimensionless): 0.230771
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997348
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:12:21 (597444): called boinc_finish(0)

</stderr_txt>
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