𝕏

Task 55448642

Name HuVeMOp_20240630152049369056_ORdGradInc_k_25-Pueyo_APDR-conf_416_1
Workunit 26330426
Created 30 Jun 2024, 13:20:53 UTC
Sent 30 Jun 2024, 14:47:48 UTC
Report deadline 4 Jul 2024, 0:23:48 UTC
Received 30 Jun 2024, 17:16:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 27 min 59 sec
CPU time 2 hours 26 min 4 sec
Validate state Valid
Credit 60.64
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630152049369056_ORdGradInc_k_25-Pueyo_APDR-conf_416.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630152049369056_ORdGradInc_k_25-Pueyo_APDR-conf_416_1_r1386130489_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630152049369056_ORdGradInc_k_25-Pueyo_APDR-conf_416_1_r1386130489_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 96.250061
     * GNaL_b in INaL: 0.006914
     * Gto_b in Ito: 0.074007
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031108
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.149666
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 68.960248
     * GKb_b in IKb: 0.003829
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.043147
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14523767, states[0] = 20.994486, states[40]= 0.007803
Saving checkpoint... 
Iteration: 29084119, states[0] = -4.904060, states[40]= 0.003435
Saving checkpoint... 
Iteration: 43733234, states[0] = -94.790252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58419477, states[0] = -94.914703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73286752, states[0] = -94.837958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87952042, states[0] = -94.910045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102298420, states[0] = -94.840723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116945950, states[0] = -94.903971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131236851, states[0] = -94.765790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145300782, states[0] = -94.838624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159276779, states[0] = -94.815837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172837632, states[0] = -94.862925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186546835, states[0] = 14.019594, states[40]= 0.005145
Saving checkpoint... 
Iteration: 200531635, states[0] = 19.436298, states[40]= 0.006059
Saving checkpoint... 
Iteration: 214735491, states[0] = -94.761370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229055824, states[0] = 10.518845, states[40]= 0.004997
Saving checkpoint... 
Iteration: 243663458, states[0] = -85.200553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258314119, states[0] = -94.847216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272582491, states[0] = -2.292917, states[40]= 0.003900
Saving checkpoint... 
Iteration: 286928469, states[0] = -94.896423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301124525, states[0] = -38.789699, states[40]= 0.000160
Saving checkpoint... 
Iteration: 315574734, states[0] = 2.090153, states[40]= 0.004501
Saving checkpoint... 
Iteration: 330022740, states[0] = 21.988344, states[40]= 0.008230
Saving checkpoint... 
Iteration: 344267724, states[0] = -94.804740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358245893, states[0] = -94.776712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372386833, states[0] = -94.884243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386458353, states[0] = -94.902510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400161194, states[0] = -81.649501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413712328, states[0] = -94.720547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427188966, states[0] = -94.662541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440842071, states[0] = -94.864506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454483540, states[0] = -94.906462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468086976, states[0] = -5.298605, states[40]= 0.003324
Saving checkpoint... 
Iteration: 481884756, states[0] = -94.883438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495631380, states[0] = -45.565394, states[40]= 0.000058
Saving checkpoint... 
Iteration: 509301713, states[0] = -94.837555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523164557, states[0] = -86.790775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536973742, states[0] = -94.904974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550969180, states[0] = -94.904248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564905401, states[0] = -94.890119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579122400, states[0] = -36.768443, states[40]= 0.000213
Saving checkpoint... 
Iteration: 593079915, states[0] = -0.737606, states[40]= 0.004149
Saving checkpoint... 
Iteration: 607176191, states[0] = -94.207343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621337714, states[0] = -94.861985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636169323, states[0] = -91.834422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651048863, states[0] = 13.250756, states[40]= 0.005102
Saving checkpoint... 
Iteration: 666121670, states[0] = -36.081017, states[40]= 0.000234
Saving checkpoint... 
Iteration: 681141349, states[0] = -56.073914, states[40]= 0.000010
Saving checkpoint... 
Iteration: 695942551, states[0] = -94.899282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710976299, states[0] = -94.905261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726258034, states[0] = -94.792832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741419847, states[0] = -94.893999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756849431, states[0] = -94.868171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771969802, states[0] = -94.904217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786712125, states[0] = -94.719937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801217333, states[0] = -94.729706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816292611, states[0] = -94.829645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831285872, states[0] = -94.823434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846160154, states[0] = -79.990641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861229791, states[0] = -94.751527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876351480, states[0] = -94.869125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891465762, states[0] = -94.903488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906048268, states[0] = 13.479187, states[40]= 0.005114
Saving checkpoint... 
Iteration: 920548678, states[0] = 13.321887, states[40]= 0.005106
Saving checkpoint... 
Iteration: 935066210, states[0] = 6.151625, states[40]= 0.004816
Saving checkpoint... 
Iteration: 949393607, states[0] = -94.886210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963821630, states[0] = -94.851915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978472696, states[0] = -94.904552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993304282, states[0] = -94.839324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008047152, states[0] = 13.905740, states[40]= 0.005138
Saving checkpoint... 
Iteration: 1022592273, states[0] = -9.400740, states[40]= 0.002447
Saving checkpoint... 
Iteration: 1037071809, states[0] = 3.551546, states[40]= 0.004637
Saving checkpoint... 
Iteration: 1051638314, states[0] = -52.815620, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1065961663, states[0] = -94.902690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080461033, states[0] = -94.902572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094926824, states[0] = -94.895528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109949302, states[0] = -94.900395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125002763, states[0] = 39.374710, states[40]= 0.123822
Saving checkpoint... 
Iteration: 1139875823, states[0] = -94.879700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154856483, states[0] = -94.871377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169721968, states[0] = -94.737879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184578938, states[0] = -0.176260, states[40]= 0.004229
Saving checkpoint... 
Iteration: 1199413193, states[0] = -94.891962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214321852, states[0] = -94.851914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229240415, states[0] = -94.768151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244104830, states[0] = -20.607113, states[40]= 0.000945
Saving checkpoint... 
Iteration: 1259207728, states[0] = -94.711124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273987306, states[0] = -94.906497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288791520, states[0] = -94.828390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303473002, states[0] = -94.904408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318004329, states[0] = 31.954761, states[40]= 0.146073
Saving checkpoint... 
Iteration: 1332780320, states[0] = -94.817699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347306959, states[0] = -94.841201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362152566, states[0] = -69.030773, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377014037, states[0] = 23.824987, states[40]= 0.022038
Saving checkpoint... 
Iteration: 1391948526, states[0] = -94.900078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406743760, states[0] = -94.773007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421906761, states[0] = -94.890013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437275643, states[0] = -94.812809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452182562, states[0] = -94.588614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467551123, states[0] = 12.376963, states[40]= 0.005063
Saving checkpoint... 
Iteration: 1482778410, states[0] = -94.815666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498001312, states[0] = 47.835669, states[40]= 0.049803
Saving checkpoint... 
Iteration: 1512526469, states[0] = -95.090822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527756532, states[0] = -94.755742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543278160, states[0] = -10.377626, states[40]= 0.002543
Saving checkpoint... 
Iteration: 1558642192, states[0] = -88.071291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573799500, states[0] = -95.208681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589258403, states[0] = -94.919383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604212437, states[0] = -47.621593, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1619126603, states[0] = 19.667398, states[40]= 0.008001
Saving checkpoint... 
Iteration: 1634251258, states[0] = -94.426422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649285003, states[0] = -95.062177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664025174, states[0] = -95.138902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679218908, states[0] = -55.453234, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1694608175, states[0] = -95.110708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709848597, states[0] = -93.810544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725007380, states[0] = 27.238356, states[40]= 0.087442
Saving checkpoint... 
Iteration: 1740377105, states[0] = -10.143090, states[40]= 0.002607
Saving checkpoint... 
Iteration: 1755584460, states[0] = -95.205424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770624430, states[0] = 20.489650, states[40]= 0.008684
Saving checkpoint... 
Iteration: 1785420255, states[0] = -57.101334, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1800112011, states[0] = -41.076854, states[40]= 0.000123
Saving checkpoint... 
Iteration: 1815404983, states[0] = -94.937191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830670835, states[0] = -93.607871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846177544, states[0] = -94.468397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861476881, states[0] = -94.917573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876785760, states[0] = -94.831006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891786472, states[0] = -94.828711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906796118, states[0] = -94.835482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921818069, states[0] = -94.851127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936791241, states[0] = -94.829155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951662097, states[0] = -83.182772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967005703, states[0] = 28.517486, states[40]= 0.126820
Saving checkpoint... 
Iteration: 1982234607, states[0] = -94.759041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997553529, states[0] = 11.430550, states[40]= 0.005028
Saving checkpoint... 
Iteration: 2012769890, states[0] = -94.806310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028103706, states[0] = -19.584277, states[40]= 0.001009
Saving checkpoint... 
Iteration: 2043196852, states[0] = -94.687823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058527826, states[0] = 20.610528, states[40]= 0.006657
Saving checkpoint... 
Iteration: 2073380330, states[0] = -94.880849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088217954, states[0] = -94.730048, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.783457
 - CaMKt in component CaMK (millimolar): 0.006896
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.608912
 - nass in component intracellular_ions (millimolar): 6.608971
 - ki in component intracellular_ions (millimolar): 145.370972
 - kss in component intracellular_ions (millimolar): 145.370953
 - cansr in component intracellular_ions (millimolar): 1.303836
 - cajsr in component intracellular_ions (millimolar): 1.265582
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003662
 - hf in component INa (dimensionless): 0.877931
 - hs in component INa (dimensionless): 0.877926
 - j in component INa (dimensionless): 0.877896
 - hsp in component INa (dimensionless): 0.721941
 - jp in component INa (dimensionless): 0.877876
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.705414
 - hLp in component INaL (dimensionless): 0.444403
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.615184
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.688301
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930042
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999868
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001575
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.344324
 - xs1 in component IKs (dimensionless): 0.250246
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997368
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:15:59 (597445): called boinc_finish(0)

</stderr_txt>
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