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Task 55447894

Name HuVeMOp_20240630151541569204_ORdGradInc_k_25-Pueyo_APDR-conf_190_1
Workunit 26330074
Created 30 Jun 2024, 13:15:55 UTC
Sent 30 Jun 2024, 14:44:09 UTC
Report deadline 4 Jul 2024, 0:20:09 UTC
Received 30 Jun 2024, 17:55:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217006
Run time 2 hours 40 min 55 sec
CPU time 2 hours 8 min 2 sec
Validate state Valid
Credit 56.75
Device peak FLOPS 4.06 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.76 MB
Peak swap size 32.57 GB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630151541569204_ORdGradInc_k_25-Pueyo_APDR-conf_190.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630151541569204_ORdGradInc_k_25-Pueyo_APDR-conf_190_1_r1272270760_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630151541569204_ORdGradInc_k_25-Pueyo_APDR-conf_190_1_r1272270760_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 109.274616
     * GNaL_b in INaL: 0.005844
     * Gto_b in Ito: 0.094451
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032371
     * GKs_b in IKs: 0.001798
     * GK1_b in IK1: 0.173123
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 65.731608
     * GKb_b in IKb: 0.003887
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019211
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 24209234, states[0] = -94.917799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48686917, states[0] = -94.852646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72473516, states[0] = -95.073035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97185478, states[0] = -94.838780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122397122, states[0] = -95.051402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147249798, states[0] = -94.951133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170876039, states[0] = -95.043126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195833420, states[0] = -95.023352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220795684, states[0] = -94.997739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245198550, states[0] = -94.864708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269657149, states[0] = -85.531880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294232826, states[0] = -94.926403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318234563, states[0] = -94.929018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342971696, states[0] = -95.066321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367346445, states[0] = -95.029895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391371366, states[0] = -95.040824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415794272, states[0] = -94.996357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440702607, states[0] = -94.872787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465414504, states[0] = -95.054614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490186293, states[0] = -94.837402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515619179, states[0] = -37.531595, states[40]= 0.000191
Saving checkpoint... 
Iteration: 539817996, states[0] = -95.013623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565100727, states[0] = -20.226503, states[40]= 0.000961
Saving checkpoint... 
Iteration: 589514560, states[0] = 21.041184, states[40]= 0.019308
Saving checkpoint... 
Iteration: 614063054, states[0] = 5.940718, states[40]= 0.004705
Saving checkpoint... 
Iteration: 638341579, states[0] = -95.027235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663241836, states[0] = -94.939317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688050632, states[0] = 10.954841, states[40]= 0.004835
Saving checkpoint... 
Iteration: 712252518, states[0] = -94.953450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737309827, states[0] = -95.007953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760970854, states[0] = -95.065878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785466328, states[0] = -95.065142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810020650, states[0] = 20.146770, states[40]= 0.008561
Saving checkpoint... 
Iteration: 834980798, states[0] = -95.067299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859174506, states[0] = -94.761769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884343649, states[0] = -95.028111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909265627, states[0] = -94.968705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934166210, states[0] = -94.009957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958466144, states[0] = -95.064983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982623816, states[0] = -42.105584, states[40]= 0.000099
Saving checkpoint... 
Iteration: 1006675149, states[0] = -94.772812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032145659, states[0] = -66.660343, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1056709391, states[0] = -94.885596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081645718, states[0] = -66.739217, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1105595808, states[0] = -15.663800, states[40]= 0.001379
Saving checkpoint... 
Iteration: 1130725265, states[0] = -94.913743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155009607, states[0] = 21.885090, states[40]= 0.058897
Saving checkpoint... 
Iteration: 1179920235, states[0] = -95.055541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204525306, states[0] = 19.174500, states[40]= 0.006552
Saving checkpoint... 
Iteration: 1228746692, states[0] = -94.945528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253249913, states[0] = -94.949731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278083407, states[0] = -5.216421, states[40]= 0.003337
Saving checkpoint... 
Iteration: 1302752900, states[0] = -94.953488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327548357, states[0] = 11.806886, states[40]= 0.004858
Saving checkpoint... 
Iteration: 1352520887, states[0] = 20.103625, states[40]= 0.008399
Saving checkpoint... 
Iteration: 1376793547, states[0] = -94.995044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401428144, states[0] = -95.057267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426123851, states[0] = -42.140540, states[40]= 0.000098
Saving checkpoint... 
Iteration: 1450927764, states[0] = -95.057142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476028208, states[0] = 18.448062, states[40]= 0.005973
Saving checkpoint... 
Iteration: 1499972870, states[0] = -95.065640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523976259, states[0] = -95.280624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548422559, states[0] = -65.141589, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1572510392, states[0] = -95.227608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596719177, states[0] = -61.526656, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1621337407, states[0] = -91.463105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645441662, states[0] = -95.278169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669302534, states[0] = -41.323303, states[40]= 0.000113
Saving checkpoint... 
Iteration: 1694466606, states[0] = -3.702157, states[40]= 0.004107
Saving checkpoint... 
Iteration: 1719973367, states[0] = -9.819419, states[40]= 0.002683
Saving checkpoint... 
Iteration: 1744820080, states[0] = 19.886634, states[40]= 0.010324
Saving checkpoint... 
Iteration: 1769105612, states[0] = 26.711867, states[40]= 0.133406
Saving checkpoint... 
Iteration: 1793143802, states[0] = 10.163490, states[40]= 0.005712
Saving checkpoint... 
Iteration: 1816987506, states[0] = -95.106375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842373054, states[0] = -95.059487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1866914364, states[0] = -95.062795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890894532, states[0] = -95.052389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914873076, states[0] = -95.042589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939648451, states[0] = -70.715556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1964121619, states[0] = -39.953867, states[40]= 0.000136
Saving checkpoint... 
Iteration: 1988771366, states[0] = -94.974225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013097706, states[0] = -17.427345, states[40]= 0.001183
Saving checkpoint... 
Iteration: 2037429048, states[0] = -95.056998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062111632, states[0] = -30.370392, states[40]= 0.000463
Saving checkpoint... 
Iteration: 2086108230, states[0] = -27.194170, states[40]= 0.000617
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.944666
 - CaMKt in component CaMK (millimolar): 0.007297
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.745890
 - nass in component intracellular_ions (millimolar): 6.745952
 - ki in component intracellular_ions (millimolar): 145.225850
 - kss in component intracellular_ions (millimolar): 145.225830
 - cansr in component intracellular_ions (millimolar): 1.333876
 - cajsr in component intracellular_ions (millimolar): 1.295613
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003603
 - hf in component INa (dimensionless): 0.880742
 - hs in component INa (dimensionless): 0.880737
 - j in component INa (dimensionless): 0.880708
 - hsp in component INa (dimensionless): 0.727227
 - jp in component INa (dimensionless): 0.880688
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711110
 - hLp in component INaL (dimensionless): 0.453526
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.621606
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.697006
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937328
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001682
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.323930
 - xs1 in component IKs (dimensionless): 0.239915
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997326
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:55:45 (5692): called boinc_finish(0)

</stderr_txt>
]]>