𝕏

Task 55447049

Name HuVeMOp_20240630151041517431_ORdGradInc_k_25-Pueyo_APDR-conf_916_1
Workunit 26329661
Created 30 Jun 2024, 13:10:48 UTC
Sent 30 Jun 2024, 14:29:55 UTC
Report deadline 4 Jul 2024, 0:05:55 UTC
Received 1 Jul 2024, 16:40:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232691
Run time 1 hours 30 min 27 sec
CPU time 1 hours 29 min 34 sec
Validate state Valid
Credit 63.55
Device peak FLOPS 4.35 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.90 MB
Peak swap size 6.41 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630151041517431_ORdGradInc_k_25-Pueyo_APDR-conf_916.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630151041517431_ORdGradInc_k_25-Pueyo_APDR-conf_916_1_r88541238_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630151041517431_ORdGradInc_k_25-Pueyo_APDR-conf_916_1_r88541238_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 117.221303
     * GNaL_b in INaL: 0.005979
     * Gto_b in Ito: 0.079943
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031213
     * GKs_b in IKs: 0.002130
     * GK1_b in IK1: 0.153326
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 74.477396
     * GKb_b in IKb: 0.003866
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032314
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10026673, states[0] = 18.369756, states[40]= 0.007222
Saving checkpoint... 
Iteration: 24318178, states[0] = -95.040232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38737113, states[0] = -94.925329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52987663, states[0] = -95.044829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67436898, states[0] = -95.024359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81698369, states[0] = -94.816262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96229923, states[0] = -94.870153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110373821, states[0] = -94.990546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125056339, states[0] = 8.719385, states[40]= 0.005011
Saving checkpoint... 
Iteration: 139280561, states[0] = -94.928038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153599878, states[0] = -20.344632, states[40]= 0.000951
Saving checkpoint... 
Iteration: 167909172, states[0] = -94.997535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182426820, states[0] = -95.001723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196595859, states[0] = -16.485657, states[40]= 0.001292
Saving checkpoint... 
Iteration: 210914203, states[0] = -94.998140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225432351, states[0] = -95.002494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239917885, states[0] = -94.998924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254381409, states[0] = -94.987643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268735940, states[0] = -94.870582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283242741, states[0] = -94.880616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297398857, states[0] = -94.993413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311444793, states[0] = -95.004924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325354000, states[0] = -94.976155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339440442, states[0] = -95.004008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353797526, states[0] = -94.940636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368060719, states[0] = 6.902535, states[40]= 0.004920
Saving checkpoint... 
Iteration: 382338597, states[0] = -94.968285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396557993, states[0] = 8.083828, states[40]= 0.004978
Saving checkpoint... 
Iteration: 411103262, states[0] = -23.460230, states[40]= 0.000778
Saving checkpoint... 
Iteration: 425479906, states[0] = -95.010855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439964626, states[0] = -95.008474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454375934, states[0] = -94.985410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468521963, states[0] = 21.008688, states[40]= 0.009071
Saving checkpoint... 
Iteration: 483128681, states[0] = -48.356603, states[40]= 0.000035
Saving checkpoint... 
Iteration: 497211845, states[0] = -94.829077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511861327, states[0] = -94.979379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525344498, states[0] = -94.971342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540008448, states[0] = 24.839106, states[40]= 0.077256
Saving checkpoint... 
Iteration: 550353410, states[0] = -94.975741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564834392, states[0] = -94.965834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579339921, states[0] = -94.968893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593756718, states[0] = -94.899050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608345869, states[0] = -94.971999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623034524, states[0] = 17.220968, states[40]= 0.005915
Saving checkpoint... 
Iteration: 637699294, states[0] = -94.803989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652262305, states[0] = -94.905759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666849570, states[0] = -94.973821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681461768, states[0] = -95.007857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696059362, states[0] = 7.495119, states[40]= 0.004950
Saving checkpoint... 
Iteration: 710453533, states[0] = -95.006374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720878199, states[0] = -94.986119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735118820, states[0] = -38.307098, states[40]= 0.000162
Saving checkpoint... 
Iteration: 749610196, states[0] = -30.020893, states[40]= 0.000462
Saving checkpoint... 
Iteration: 763989517, states[0] = -95.011991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778533436, states[0] = 17.594217, states[40]= 0.006029
Saving checkpoint... 
Iteration: 792272029, states[0] = -94.916536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806638648, states[0] = -59.173588, states[40]= 0.000006
Saving checkpoint... 
Iteration: 820961525, states[0] = -95.007737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836371675, states[0] = -94.983533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850881186, states[0] = -94.987151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865163101, states[0] = -91.830788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879714471, states[0] = -94.833802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893803778, states[0] = -94.945302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908040092, states[0] = 15.216074, states[40]= 0.005493
Saving checkpoint... 
Iteration: 922569151, states[0] = 2.959741, states[40]= 0.004646
Saving checkpoint... 
Iteration: 937087690, states[0] = -9.076222, states[40]= 0.002554
Saving checkpoint... 
Iteration: 951357872, states[0] = -94.977590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965645301, states[0] = -66.998125, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980172248, states[0] = -94.524287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994352846, states[0] = -94.975226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004285119, states[0] = -94.929430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019040982, states[0] = 14.883215, states[40]= 0.005444
Saving checkpoint... 
Iteration: 1033438176, states[0] = -95.003136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048075608, states[0] = -0.524281, states[40]= 0.004237
Saving checkpoint... 
Iteration: 1062398672, states[0] = -94.992908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076621516, states[0] = -40.974842, states[40]= 0.000110
Saving checkpoint... 
Iteration: 1091224373, states[0] = -94.851356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105785542, states[0] = -94.929766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120173032, states[0] = -94.571506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134923141, states[0] = -94.999629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149394327, states[0] = -94.991488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163788068, states[0] = -94.932042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178017347, states[0] = 22.073768, states[40]= 0.014097
Saving checkpoint... 
Iteration: 1192651744, states[0] = -75.939369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207055250, states[0] = 9.240007, states[40]= 0.005031
Saving checkpoint... 
Iteration: 1221485061, states[0] = -95.011138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236000821, states[0] = 48.162216, states[40]= 0.012713
Saving checkpoint... 
Iteration: 1250621472, states[0] = -40.930745, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1265234004, states[0] = -94.866982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275893335, states[0] = -94.991097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290116747, states[0] = -36.288451, states[40]= 0.000215
Saving checkpoint... 
Iteration: 1304348951, states[0] = -94.973161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318579823, states[0] = -3.147253, states[40]= 0.003800
Saving checkpoint... 
Iteration: 1333072049, states[0] = 1.461440, states[40]= 0.004493
Saving checkpoint... 
Iteration: 1347459325, states[0] = -95.007063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361587356, states[0] = -8.795643, states[40]= 0.002614
Saving checkpoint... 
Iteration: 1375839689, states[0] = -94.968325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390319321, states[0] = -94.956121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404673753, states[0] = -94.606560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418468531, states[0] = -95.008570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433125101, states[0] = -44.615000, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1447428361, states[0] = -95.000709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457703120, states[0] = -94.811396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472519213, states[0] = 21.662412, states[40]= 0.011390
Saving checkpoint... 
Iteration: 1486946447, states[0] = -95.004586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501538079, states[0] = 14.346201, states[40]= 0.006417
Saving checkpoint... 
Iteration: 1515924463, states[0] = 19.898255, states[40]= 0.009182
Saving checkpoint... 
Iteration: 1530361511, states[0] = 0.897688, states[40]= 0.004950
Saving checkpoint... 
Iteration: 1544947463, states[0] = -95.250670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559299275, states[0] = -95.185284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573672489, states[0] = -95.130187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588308875, states[0] = -48.635650, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1602721212, states[0] = -64.038577, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1616820613, states[0] = -63.324783, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1631244260, states[0] = -94.174916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645592844, states[0] = -30.770512, states[40]= 0.000418
Saving checkpoint... 
Iteration: 1660228938, states[0] = 17.614486, states[40]= 0.007721
Saving checkpoint... 
Iteration: 1674561904, states[0] = -95.284880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689235292, states[0] = -95.254905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703533832, states[0] = -84.089977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1718079750, states[0] = -95.300874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732407603, states[0] = -95.212807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746867830, states[0] = -95.290667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761129436, states[0] = -76.448787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775576169, states[0] = -95.146934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790123602, states[0] = 19.769115, states[40]= 0.009455
Saving checkpoint... 
Iteration: 1804438553, states[0] = -95.065814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818796288, states[0] = -94.982325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833175692, states[0] = -94.737395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847699331, states[0] = -94.822414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862197501, states[0] = -94.811860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876542991, states[0] = 14.011988, states[40]= 0.005352
Saving checkpoint... 
Iteration: 1891233092, states[0] = -94.870375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904811769, states[0] = -94.954034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919335699, states[0] = -94.967991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933443426, states[0] = -95.005137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948180770, states[0] = -94.747217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962419094, states[0] = -94.998725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977044653, states[0] = 13.477139, states[40]= 0.005286
Saving checkpoint... 
Iteration: 1991144427, states[0] = -65.932837, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2005656185, states[0] = -83.124994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020120985, states[0] = -40.451068, states[40]= 0.000119
Saving checkpoint... 
Iteration: 2034619092, states[0] = -38.577366, states[40]= 0.000156
Saving checkpoint... 
Iteration: 2048676067, states[0] = -94.681738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063295667, states[0] = -94.938128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077778620, states[0] = -94.922565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092354726, states[0] = -94.975474, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.888404
 - CaMKt in component CaMK (millimolar): 0.006759
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.445812
 - nass in component intracellular_ions (millimolar): 6.445871
 - ki in component intracellular_ions (millimolar): 145.534720
 - kss in component intracellular_ions (millimolar): 145.534700
 - cansr in component intracellular_ions (millimolar): 1.302385
 - cajsr in component intracellular_ions (millimolar): 1.264793
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003623
 - hf in component INa (dimensionless): 0.879767
 - hs in component INa (dimensionless): 0.879763
 - j in component INa (dimensionless): 0.879733
 - hsp in component INa (dimensionless): 0.725390
 - jp in component INa (dimensionless): 0.879713
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709549
 - hLp in component INaL (dimensionless): 0.451514
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621759
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.696529
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935583
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001579
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.340831
 - xs1 in component IKs (dimensionless): 0.239551
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997341
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:39:57 (24816): called boinc_finish(0)

</stderr_txt>
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