𝕏

Task 55446599

Name HuVeMOp_20240630150053895843_ORdGradInc_k_25-Pueyo_APDR-conf_403_1
Workunit 26329461
Created 30 Jun 2024, 13:00:59 UTC
Sent 30 Jun 2024, 14:25:37 UTC
Report deadline 4 Jul 2024, 0:01:37 UTC
Received 1 Jul 2024, 13:36:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236597
Run time 2 hours 19 min 30 sec
CPU time 2 hours 17 min
Validate state Valid
Credit 62.89
Device peak FLOPS 4.22 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.89 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.20.5</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630150053895843_ORdGradInc_k_25-Pueyo_APDR-conf_403.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630150053895843_ORdGradInc_k_25-Pueyo_APDR-conf_403_1_r1699923206_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630150053895843_ORdGradInc_k_25-Pueyo_APDR-conf_403_1_r1699923206_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.440348
     * GNaL_b in INaL: 0.005181
     * Gto_b in Ito: 0.088682
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030736
     * GKs_b in IKs: 0.002145
     * GK1_b in IK1: 0.162361
     * Gncx_b in INaCa_i: 0.000977
     * Pnak_b in INaK: 69.016258
     * GKb_b in IKb: 0.003700
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031376
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15979999, states[0] = -94.936651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31888391, states[0] = -94.890331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47901790, states[0] = -94.881191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63935428, states[0] = -94.882109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80046095, states[0] = 12.783834, states[40]= 0.004982
Saving checkpoint... 
Iteration: 96037316, states[0] = 15.996380, states[40]= 0.005285
Saving checkpoint... 
Iteration: 112193905, states[0] = -94.660272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128389501, states[0] = -94.858983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144431438, states[0] = -94.870021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160679034, states[0] = -94.584537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176401742, states[0] = -94.861498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192532218, states[0] = 17.723187, states[40]= 0.005667
Saving checkpoint... 
Iteration: 208575242, states[0] = 0.072485, states[40]= 0.004247
Saving checkpoint... 
Iteration: 224864425, states[0] = -94.847636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241257503, states[0] = -94.766135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257500684, states[0] = 42.085166, states[40]= 0.006314
Saving checkpoint... 
Iteration: 273394574, states[0] = -94.858783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289920460, states[0] = -94.866176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305942268, states[0] = -94.871149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321823387, states[0] = -94.825832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338069479, states[0] = 3.099142, states[40]= 0.004562
Saving checkpoint... 
Iteration: 354226927, states[0] = -94.721357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370640654, states[0] = -59.144294, states[40]= 0.000006
Saving checkpoint... 
Iteration: 387087007, states[0] = -7.867157, states[40]= 0.002781
Saving checkpoint... 
Iteration: 402987081, states[0] = -94.878604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418937409, states[0] = -94.870036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435172808, states[0] = -94.324276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451380859, states[0] = -94.853909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467416225, states[0] = -94.864945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483245722, states[0] = -94.750295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499207214, states[0] = -94.684941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515320628, states[0] = -94.823901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531354279, states[0] = -94.842740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547116689, states[0] = -35.039309, states[40]= 0.000264
Saving checkpoint... 
Iteration: 563715110, states[0] = -94.700155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579720419, states[0] = -94.709873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595761588, states[0] = -94.770810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612073004, states[0] = 1.299938, states[40]= 0.004392
Saving checkpoint... 
Iteration: 628234894, states[0] = -94.734122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644536156, states[0] = 16.451264, states[40]= 0.005354
Saving checkpoint... 
Iteration: 660438066, states[0] = -94.870010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676315583, states[0] = -94.820387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692229103, states[0] = -94.724756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708303152, states[0] = -94.811214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724159660, states[0] = -85.393018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740152641, states[0] = -74.003650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756100270, states[0] = -19.754228, states[40]= 0.000990
Saving checkpoint... 
Iteration: 772083809, states[0] = -5.409873, states[40]= 0.003303
Saving checkpoint... 
Iteration: 788108631, states[0] = -27.523585, states[40]= 0.000597
Saving checkpoint... 
Iteration: 803944219, states[0] = -94.871193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819950589, states[0] = -94.872433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836428753, states[0] = -94.867800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852339828, states[0] = -94.835173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868517801, states[0] = 21.244601, states[40]= 0.011883
Saving checkpoint... 
Iteration: 884615968, states[0] = -34.362183, states[40]= 0.000288
Saving checkpoint... 
Iteration: 900745928, states[0] = -94.750293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917110940, states[0] = -29.669379, states[40]= 0.000493
Saving checkpoint... 
Iteration: 933340541, states[0] = -94.835503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949426841, states[0] = -94.867270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965129618, states[0] = -47.625955, states[40]= 0.000041
Saving checkpoint... 
Iteration: 980994568, states[0] = -94.879176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997097173, states[0] = -16.867451, states[40]= 0.001240
Saving checkpoint... 
Iteration: 1012937445, states[0] = -94.869632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028775836, states[0] = -94.786358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045037825, states[0] = 15.883617, states[40]= 0.005258
Saving checkpoint... 
Iteration: 1061537177, states[0] = 16.105761, states[40]= 0.005293
Saving checkpoint... 
Iteration: 1077409740, states[0] = -94.862761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093436565, states[0] = -94.869385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109514874, states[0] = 21.697700, states[40]= 0.018562
Saving checkpoint... 
Iteration: 1125034769, states[0] = 16.911564, states[40]= 0.005449
Saving checkpoint... 
Iteration: 1141098770, states[0] = -18.355293, states[40]= 0.001097
Saving checkpoint... 
Iteration: 1157008101, states[0] = 23.443983, states[40]= 0.083697
Saving checkpoint... 
Iteration: 1173111156, states[0] = -29.870153, states[40]= 0.000483
Saving checkpoint... 
Iteration: 1188930170, states[0] = -94.867885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204914173, states[0] = -94.863887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220793731, states[0] = -94.803121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236851782, states[0] = -94.841054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252915608, states[0] = -94.864237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268875792, states[0] = -94.851434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285157434, states[0] = -81.716176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301029821, states[0] = 18.450012, states[40]= 0.005943
Saving checkpoint... 
Iteration: 1317029510, states[0] = 18.540514, states[40]= 0.005985
Saving checkpoint... 
Iteration: 1332849343, states[0] = -94.839790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349126784, states[0] = -44.776185, states[40]= 0.000064
Saving checkpoint... 
Iteration: 1365208389, states[0] = -94.686664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381458430, states[0] = -94.873485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397443108, states[0] = -94.870555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413499127, states[0] = -94.879435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429470956, states[0] = -94.875543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445546627, states[0] = 12.700152, states[40]= 0.004971
Saving checkpoint... 
Iteration: 1461549350, states[0] = 11.668642, states[40]= 0.004928
Saving checkpoint... 
Iteration: 1477694057, states[0] = -94.656682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493490472, states[0] = -94.878297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509672295, states[0] = -6.049252, states[40]= 0.003513
Saving checkpoint... 
Iteration: 1525516459, states[0] = 21.838135, states[40]= 0.016102
Saving checkpoint... 
Iteration: 1541319541, states[0] = -95.057843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557825132, states[0] = -95.074533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573848699, states[0] = 8.212867, states[40]= 0.005596
Saving checkpoint... 
Iteration: 1589666079, states[0] = -95.130884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605448632, states[0] = -94.593234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620954008, states[0] = 5.203422, states[40]= 0.005369
Saving checkpoint... 
Iteration: 1637069680, states[0] = -95.137438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652531779, states[0] = -77.788367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1668450266, states[0] = -94.736773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683899659, states[0] = -95.161312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699874773, states[0] = -10.550995, states[40]= 0.002516
Saving checkpoint... 
Iteration: 1715664045, states[0] = -95.132917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731453020, states[0] = -94.851970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747178856, states[0] = -95.146114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762758214, states[0] = -95.127128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1778732861, states[0] = 15.769906, states[40]= 0.006570
Saving checkpoint... 
Iteration: 1794496606, states[0] = -95.036331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810729356, states[0] = -94.769232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826402686, states[0] = -94.891821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841983892, states[0] = -94.897262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858003250, states[0] = 34.984882, states[40]= 0.152993
Saving checkpoint... 
Iteration: 1873934741, states[0] = -94.876170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1889518002, states[0] = 21.170809, states[40]= 0.011568
Saving checkpoint... 
Iteration: 1892981139, states[0] = -94.881106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908411981, states[0] = -94.865543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924094281, states[0] = -14.283493, states[40]= 0.001568
Saving checkpoint... 
Iteration: 1939707626, states[0] = -94.685827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955895309, states[0] = -94.858453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1972146687, states[0] = -66.058550, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1987721145, states[0] = -94.710399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003335949, states[0] = -94.832329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019199533, states[0] = -94.668214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035004397, states[0] = 29.614838, states[40]= 0.161660
Saving checkpoint... 
Iteration: 2050874021, states[0] = -94.850184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066617719, states[0] = -36.009472, states[40]= 0.000232
Saving checkpoint... 
Iteration: 2081926918, states[0] = -94.866459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097244226, states[0] = -94.747000, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.754888
 - CaMKt in component CaMK (millimolar): 0.007142
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.678447
 - nass in component intracellular_ions (millimolar): 6.678506
 - ki in component intracellular_ions (millimolar): 145.296507
 - kss in component intracellular_ions (millimolar): 145.296489
 - cansr in component intracellular_ions (millimolar): 1.321740
 - cajsr in component intracellular_ions (millimolar): 1.283561
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003673
 - hf in component INa (dimensionless): 0.877427
 - hs in component INa (dimensionless): 0.877422
 - j in component INa (dimensionless): 0.877392
 - hsp in component INa (dimensionless): 0.720998
 - jp in component INa (dimensionless): 0.877372
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.705628
 - hLp in component INaL (dimensionless): 0.446442
 - a in component Ito (dimensionless): 0.000630
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.619207
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.693696
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936100
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001635
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332151
 - xs1 in component IKs (dimensionless): 0.240835
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997376
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:35:54 (98320): called boinc_finish(0)

</stderr_txt>
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