𝕏

Task 55446343

Name HuVeMOp_20240630150042760138_ORdGradInc_k_25-Pueyo_APDR-conf_918_1
Workunit 26329336
Created 30 Jun 2024, 13:00:48 UTC
Sent 30 Jun 2024, 14:23:16 UTC
Report deadline 3 Jul 2024, 23:59:16 UTC
Received 3 Jul 2024, 8:59:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226324
Run time 2 hours 48 min 4 sec
CPU time 2 hours 30 min 42 sec
Validate state Valid
Credit 64.36
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.48 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630150042760138_ORdGradInc_k_25-Pueyo_APDR-conf_918.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630150042760138_ORdGradInc_k_25-Pueyo_APDR-conf_918_1_r1446462691_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630150042760138_ORdGradInc_k_25-Pueyo_APDR-conf_918_1_r1446462691_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 98.735985
     * GNaL_b in INaL: 0.004934
     * Gto_b in Ito: 0.084444
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032425
     * GKs_b in IKs: 0.002029
     * GK1_b in IK1: 0.171629
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 66.242455
     * GKb_b in IKb: 0.003905
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046146
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13674460, states[0] = -94.903864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26729238, states[0] = -94.978884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40815230, states[0] = -95.047015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54199035, states[0] = -94.907840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68154861, states[0] = -90.752626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81331506, states[0] = -95.040897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94714301, states[0] = -94.924729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108225696, states[0] = -94.941207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121661381, states[0] = -94.136872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134804433, states[0] = -95.020002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149253085, states[0] = -94.974669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162537005, states[0] = 15.621756, states[40]= 0.005365
Saving checkpoint... 
Iteration: 175894028, states[0] = -95.058709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188821805, states[0] = -95.029481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201977043, states[0] = -95.074659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215018536, states[0] = 21.008425, states[40]= 0.010935
Saving checkpoint... 
Iteration: 228176273, states[0] = -94.841920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241779171, states[0] = -94.999464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255344291, states[0] = -95.040482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269975521, states[0] = -95.074243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283195285, states[0] = -94.885772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297018594, states[0] = 20.998011, states[40]= 0.010866
Saving checkpoint... 
Iteration: 311426536, states[0] = -95.066058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325084968, states[0] = -8.867092, states[40]= 0.002587
Saving checkpoint... 
Iteration: 338251285, states[0] = -94.971573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351504851, states[0] = 28.268161, states[40]= 0.152802
Saving checkpoint... 
Iteration: 363864075, states[0] = -95.048464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377169219, states[0] = -94.777666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389489034, states[0] = -95.075797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402365818, states[0] = -95.049080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415912069, states[0] = -95.062775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429329664, states[0] = -95.033259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442151294, states[0] = -84.304326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454906806, states[0] = -95.061472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467289109, states[0] = -95.007368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480621198, states[0] = -44.433950, states[40]= 0.000064
Saving checkpoint... 
Iteration: 493394502, states[0] = -95.058204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506366883, states[0] = -95.049397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519715135, states[0] = -94.921325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532473946, states[0] = -95.073831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544954462, states[0] = -95.070981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557955056, states[0] = -95.071067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570881299, states[0] = -95.054231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584370153, states[0] = -95.050510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596729357, states[0] = -94.943191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609805957, states[0] = -95.019300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622549048, states[0] = 10.997152, states[40]= 0.004963
Saving checkpoint... 
Iteration: 635002139, states[0] = 42.666896, states[40]= 0.104398
Saving checkpoint... 
Iteration: 647710529, states[0] = -94.913479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660888245, states[0] = -95.056294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673787852, states[0] = -95.006247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686655931, states[0] = -91.076329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700240018, states[0] = -94.957627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713247870, states[0] = -94.967332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725832819, states[0] = -95.034669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738724084, states[0] = -94.935323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751392219, states[0] = -95.057388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764174475, states[0] = -94.833397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776745325, states[0] = -94.964227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789206153, states[0] = -94.905709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802321214, states[0] = -95.028444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815710857, states[0] = -94.913929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828131274, states[0] = -55.464808, states[40]= 0.000011
Saving checkpoint... 
Iteration: 841030525, states[0] = 17.850059, states[40]= 0.005930
Saving checkpoint... 
Iteration: 854201646, states[0] = -94.897457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867869134, states[0] = -95.049961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881163506, states[0] = -94.459919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893821345, states[0] = -95.028456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906694928, states[0] = -94.884635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919817157, states[0] = -95.026034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932974743, states[0] = -95.073669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945858636, states[0] = -95.045997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958710681, states[0] = -94.913531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972328583, states[0] = -95.032331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985575569, states[0] = -1.835196, states[40]= 0.003993
Saving checkpoint... 
Iteration: 998279995, states[0] = -94.999596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011871794, states[0] = -95.050795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024766354, states[0] = -94.987100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038146874, states[0] = -76.326731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051292080, states[0] = -95.009248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063985320, states[0] = -95.074909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077681284, states[0] = -94.855951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091636296, states[0] = -61.319361, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1105089128, states[0] = -12.634596, states[40]= 0.001846
Saving checkpoint... 
Iteration: 1117850503, states[0] = -95.042570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131026911, states[0] = 18.952526, states[40]= 0.006508
Saving checkpoint... 
Iteration: 1144112110, states[0] = -35.139981, states[40]= 0.000245
Saving checkpoint... 
Iteration: 1157160062, states[0] = -93.719119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169693832, states[0] = -94.882311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182562957, states[0] = 4.984435, states[40]= 0.004718
Saving checkpoint... 
Iteration: 1195379962, states[0] = -95.053388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208606349, states[0] = -29.443355, states[40]= 0.000473
Saving checkpoint... 
Iteration: 1221917777, states[0] = -95.063552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235228783, states[0] = -94.941935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247650840, states[0] = -83.482284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260731480, states[0] = -94.945759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274168294, states[0] = -94.755511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286421535, states[0] = -95.064337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299309320, states[0] = -95.021004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312400252, states[0] = -95.059217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325353467, states[0] = -95.043668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337937094, states[0] = -95.067443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350511306, states[0] = 22.370057, states[40]= 0.038289
Saving checkpoint... 
Iteration: 1364006467, states[0] = 25.136485, states[40]= 0.117402
Saving checkpoint... 
Iteration: 1377045262, states[0] = 12.503554, states[40]= 0.005039
Saving checkpoint... 
Iteration: 1390006152, states[0] = 25.578174, states[40]= 0.124961
Saving checkpoint... 
Iteration: 1402935907, states[0] = -95.067176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415607559, states[0] = -30.634574, states[40]= 0.000419
Saving checkpoint... 
Iteration: 1428350388, states[0] = -95.042313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441075505, states[0] = -1.794290, states[40]= 0.003999
Saving checkpoint... 
Iteration: 1454199625, states[0] = -94.893274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467030675, states[0] = 17.802088, states[40]= 0.005911
Saving checkpoint... 
Iteration: 1479940837, states[0] = -95.068038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492490189, states[0] = -95.075190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505609246, states[0] = -95.205521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1518693148, states[0] = -31.997420, states[40]= 0.000357
Saving checkpoint... 
Iteration: 1531244170, states[0] = 10.065884, states[40]= 0.005786
Saving checkpoint... 
Iteration: 1543954485, states[0] = -95.114586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556636408, states[0] = -95.276881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568919408, states[0] = -95.259310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581197704, states[0] = -95.227978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593999304, states[0] = -41.153482, states[40]= 0.000109
Saving checkpoint... 
Iteration: 1607086715, states[0] = -95.330203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620293387, states[0] = -95.335233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632787385, states[0] = -95.213134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645891585, states[0] = -32.485505, states[40]= 0.000340
Saving checkpoint... 
Iteration: 1658546672, states[0] = -95.063099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671061118, states[0] = -0.721520, states[40]= 0.004685
Saving checkpoint... 
Iteration: 1683797601, states[0] = -95.232993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696204077, states[0] = 32.051626, states[40]= 0.137031
Saving checkpoint... 
Iteration: 1709141336, states[0] = 11.085268, states[40]= 0.005932
Saving checkpoint... 
Iteration: 1722337529, states[0] = 12.992386, states[40]= 0.006179
Saving checkpoint... 
Iteration: 1735449063, states[0] = -95.301920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748610839, states[0] = -95.254785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761676520, states[0] = -15.429875, states[40]= 0.001593
Saving checkpoint... 
Iteration: 1774908884, states[0] = -53.018473, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1787435525, states[0] = 13.959965, states[40]= 0.006340
Saving checkpoint... 
Iteration: 1800540869, states[0] = 13.015799, states[40]= 0.005079
Saving checkpoint... 
Iteration: 1814245680, states[0] = -95.003666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1828006383, states[0] = 25.082386, states[40]= 0.121168
Saving checkpoint... 
Iteration: 1841651018, states[0] = -86.489134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1854834472, states[0] = -95.047913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867518380, states[0] = 20.953789, states[40]= 0.011081
Saving checkpoint... 
Iteration: 1880296636, states[0] = -95.018350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894101751, states[0] = -25.202426, states[40]= 0.000671
Saving checkpoint... 
Iteration: 1907740780, states[0] = -94.960654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922470555, states[0] = -95.074251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936808843, states[0] = -95.021460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950250184, states[0] = -94.970013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963473641, states[0] = -95.073347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976928356, states[0] = -95.065637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989998748, states[0] = -95.076000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002649963, states[0] = -81.901472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015332556, states[0] = -95.033740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028635416, states[0] = -60.270421, states[40]= 0.000005
Saving checkpoint... 
Iteration: 2041400770, states[0] = -95.058864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053972938, states[0] = -95.072658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067311523, states[0] = -95.021835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079896251, states[0] = -95.057583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092693993, states[0] = -94.881954, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.951675
 - CaMKt in component CaMK (millimolar): 0.006964
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.685771
 - nass in component intracellular_ions (millimolar): 6.685830
 - ki in component intracellular_ions (millimolar): 145.291083
 - kss in component intracellular_ions (millimolar): 145.291064
 - cansr in component intracellular_ions (millimolar): 1.313388
 - cajsr in component intracellular_ions (millimolar): 1.275866
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003600
 - hf in component INa (dimensionless): 0.880863
 - hs in component INa (dimensionless): 0.880858
 - j in component INa (dimensionless): 0.880833
 - hsp in component INa (dimensionless): 0.727459
 - jp in component INa (dimensionless): 0.880816
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.712530
 - hLp in component INaL (dimensionless): 0.457451
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.626881
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.703153
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.939160
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999899
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001602
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.318548
 - xs1 in component IKs (dimensionless): 0.232941
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997324
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:59:48 (34706): called boinc_finish(0)

</stderr_txt>
]]>


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