𝕏

Task 55446183

Name HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_496_1
Workunit 26329266
Created 30 Jun 2024, 12:51:06 UTC
Sent 30 Jun 2024, 14:23:16 UTC
Report deadline 3 Jul 2024, 23:59:16 UTC
Received 3 Jul 2024, 9:58:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226324
Run time 2 hours 46 min 35 sec
CPU time 2 hours 31 min 6 sec
Validate state Valid
Credit 63.00
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_496.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_496_1_r1668901686_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_496_1_r1668901686_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 116.308203
     * GNaL_b in INaL: 0.006843
     * Gto_b in Ito: 0.085731
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032955
     * GKs_b in IKs: 0.002132
     * GK1_b in IK1: 0.148638
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 74.755530
     * GKb_b in IKb: 0.003844
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019184
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14753164, states[0] = -95.020742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28155974, states[0] = -88.505003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41546026, states[0] = 12.895262, states[40]= 0.005114
Saving checkpoint... 
Iteration: 55701388, states[0] = -94.830604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69083581, states[0] = -5.365396, states[40]= 0.003351
Saving checkpoint... 
Iteration: 82133978, states[0] = -54.115829, states[40]= 0.000014
Saving checkpoint... 
Iteration: 95897528, states[0] = -95.012577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109909872, states[0] = -95.013584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123624415, states[0] = -43.113882, states[40]= 0.000083
Saving checkpoint... 
Iteration: 135971350, states[0] = -95.024893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149074028, states[0] = 1.224856, states[40]= 0.004426
Saving checkpoint... 
Iteration: 162216843, states[0] = -94.834216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175498839, states[0] = -95.027259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188874847, states[0] = -94.995569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201722714, states[0] = -94.844885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214768831, states[0] = -94.915936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228267545, states[0] = -94.914275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241463215, states[0] = -95.020867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254360294, states[0] = -94.988389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266712436, states[0] = -94.823954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279714808, states[0] = -94.828835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292711400, states[0] = -94.821737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305232487, states[0] = -94.862358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317935548, states[0] = -95.014800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331017628, states[0] = 21.955673, states[40]= 0.012916
Saving checkpoint... 
Iteration: 343656266, states[0] = -82.344330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356828733, states[0] = -94.970132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370157205, states[0] = -83.841042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383671983, states[0] = -94.414820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397189688, states[0] = -94.770863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410165830, states[0] = -92.983513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422783010, states[0] = -94.931573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435324181, states[0] = -94.966980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448337914, states[0] = -94.975924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461578047, states[0] = -1.037409, states[40]= 0.004127
Saving checkpoint... 
Iteration: 474539211, states[0] = 16.020944, states[40]= 0.005352
Saving checkpoint... 
Iteration: 487513268, states[0] = 22.683419, states[40]= 0.026576
Saving checkpoint... 
Iteration: 501364326, states[0] = -94.990107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514112863, states[0] = -31.403777, states[40]= 0.000407
Saving checkpoint... 
Iteration: 527750151, states[0] = -94.890540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540790144, states[0] = -94.938726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553342838, states[0] = -94.978790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566470340, states[0] = -95.021849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579215329, states[0] = -94.829679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591667914, states[0] = -93.732953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605056313, states[0] = 9.485005, states[40]= 0.004941
Saving checkpoint... 
Iteration: 618568873, states[0] = 3.915401, states[40]= 0.004674
Saving checkpoint... 
Iteration: 631647286, states[0] = -68.953960, states[40]= 0.000001
Saving checkpoint... 
Iteration: 644183319, states[0] = -94.745364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657403464, states[0] = -95.005497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671072169, states[0] = 2.256328, states[40]= 0.004532
Saving checkpoint... 
Iteration: 683965287, states[0] = -95.020870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696979248, states[0] = -95.023266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709551516, states[0] = 11.409619, states[40]= 0.005004
Saving checkpoint... 
Iteration: 722468229, states[0] = -95.021379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736213792, states[0] = -94.826426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750020400, states[0] = 21.436769, states[40]= 0.009642
Saving checkpoint... 
Iteration: 764865238, states[0] = -94.990374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778920265, states[0] = -95.010515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791868077, states[0] = -94.991671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804823032, states[0] = -94.965946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818275986, states[0] = -94.923684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832110642, states[0] = -29.267464, states[40]= 0.000507
Saving checkpoint... 
Iteration: 846745693, states[0] = -94.883653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861141487, states[0] = -61.802541, states[40]= 0.000004
Saving checkpoint... 
Iteration: 874670593, states[0] = -94.258791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888161194, states[0] = -89.393032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902059871, states[0] = 7.998708, states[40]= 0.004891
Saving checkpoint... 
Iteration: 915431521, states[0] = -95.013424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929248231, states[0] = -94.887447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943153709, states[0] = -78.239947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957238386, states[0] = -94.871955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970324447, states[0] = -94.966833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983988344, states[0] = -95.024493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997652821, states[0] = -76.851074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011179266, states[0] = -94.708473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025142780, states[0] = -63.332121, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1038736866, states[0] = -94.869378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052961424, states[0] = -95.019919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067000173, states[0] = -73.754314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081079886, states[0] = -2.182865, states[40]= 0.003944
Saving checkpoint... 
Iteration: 1094964702, states[0] = -95.020508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109001639, states[0] = 49.331856, states[40]= 0.062128
Saving checkpoint... 
Iteration: 1122706887, states[0] = -94.811532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136368223, states[0] = -94.991525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149856967, states[0] = -94.986099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164469115, states[0] = -95.021265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179019025, states[0] = 21.703642, states[40]= 0.010985
Saving checkpoint... 
Iteration: 1194243392, states[0] = -94.879866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208173991, states[0] = -94.556709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222228691, states[0] = -94.855016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236275205, states[0] = -94.922541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249804947, states[0] = -94.951725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263333950, states[0] = -94.972958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276836932, states[0] = -94.974811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290814108, states[0] = -94.959075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304133794, states[0] = -53.058664, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1317474659, states[0] = -95.022128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331587710, states[0] = -7.881240, states[40]= 0.002797
Saving checkpoint... 
Iteration: 1345295953, states[0] = -94.943740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359188106, states[0] = -94.765402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372632596, states[0] = -51.727992, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1386353474, states[0] = -94.984151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399869067, states[0] = -94.991746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413304170, states[0] = -94.950967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426124616, states[0] = -43.104400, states[40]= 0.000083
Saving checkpoint... 
Iteration: 1438816078, states[0] = -94.960484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451600541, states[0] = -19.616992, states[40]= 0.000999
Saving checkpoint... 
Iteration: 1464712696, states[0] = -94.823698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477454201, states[0] = -95.018232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490747264, states[0] = -94.885645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503565627, states[0] = -95.239329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516622580, states[0] = -62.526492, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1529778251, states[0] = -12.621013, states[40]= 0.002079
Saving checkpoint... 
Iteration: 1543433960, states[0] = -95.249796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556459999, states[0] = 2.084254, states[40]= 0.005099
Saving checkpoint... 
Iteration: 1569485566, states[0] = -95.169408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1582086009, states[0] = -95.173782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595145620, states[0] = 10.063209, states[40]= 0.005837
Saving checkpoint... 
Iteration: 1607768015, states[0] = -3.994440, states[40]= 0.004074
Saving checkpoint... 
Iteration: 1620920367, states[0] = 20.955504, states[40]= 0.011069
Saving checkpoint... 
Iteration: 1634289459, states[0] = -95.187278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646926665, states[0] = -95.260401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659811935, states[0] = -95.235311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672710884, states[0] = -95.233494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1685313126, states[0] = -95.237762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699596941, states[0] = -34.583601, states[40]= 0.000275
Saving checkpoint... 
Iteration: 1714033879, states[0] = -83.896841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726426949, states[0] = -95.261449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738809717, states[0] = 24.366259, states[40]= 0.058049
Saving checkpoint... 
Iteration: 1751017588, states[0] = -95.245892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764010686, states[0] = 23.920349, states[40]= 0.047304
Saving checkpoint... 
Iteration: 1777096549, states[0] = -95.204457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789831928, states[0] = 16.552881, states[40]= 0.006924
Saving checkpoint... 
Iteration: 1802610377, states[0] = -33.277441, states[40]= 0.000351
Saving checkpoint... 
Iteration: 1815365171, states[0] = -95.043136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829498903, states[0] = -95.061288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844951707, states[0] = -95.039962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858006393, states[0] = 26.106364, states[40]= 0.121309
Saving checkpoint... 
Iteration: 1870481385, states[0] = -95.033209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884238730, states[0] = -94.878875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897959463, states[0] = -95.023489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910679211, states[0] = -94.712356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924029161, states[0] = 19.257162, states[40]= 0.006314
Saving checkpoint... 
Iteration: 1937534982, states[0] = 17.453609, states[40]= 0.005632
Saving checkpoint... 
Iteration: 1950431757, states[0] = -95.013724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963282420, states[0] = -94.930585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975754958, states[0] = -94.896913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988457523, states[0] = -95.018829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001338573, states[0] = -94.975515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015315396, states[0] = -94.959692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029345446, states[0] = -94.979409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041477688, states[0] = -95.022192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054132150, states[0] = -51.236409, states[40]= 0.000023
Saving checkpoint... 
Iteration: 2067343670, states[0] = -94.978311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080074972, states[0] = 0.747576, states[40]= 0.004369
Saving checkpoint... 
Iteration: 2092992205, states[0] = -95.024330, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.901268
 - CaMKt in component CaMK (millimolar): 0.006974
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.462013
 - nass in component intracellular_ions (millimolar): 6.462075
 - ki in component intracellular_ions (millimolar): 145.515617
 - kss in component intracellular_ions (millimolar): 145.515596
 - cansr in component intracellular_ions (millimolar): 1.312846
 - cajsr in component intracellular_ions (millimolar): 1.274792
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003619
 - hf in component INa (dimensionless): 0.879991
 - hs in component INa (dimensionless): 0.879985
 - j in component INa (dimensionless): 0.879952
 - hsp in component INa (dimensionless): 0.725807
 - jp in component INa (dimensionless): 0.879930
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709662
 - hLp in component INaL (dimensionless): 0.451260
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620871
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695395
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934179
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001610
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339244
 - xs1 in component IKs (dimensionless): 0.243115
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:58:38 (35138): called boinc_finish(0)

</stderr_txt>
]]>


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