𝕏

Task 55446167

Name HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_190_1
Workunit 26329258
Created 30 Jun 2024, 12:51:05 UTC
Sent 30 Jun 2024, 14:24:05 UTC
Report deadline 4 Jul 2024, 0:00:05 UTC
Received 2 Jul 2024, 15:02:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 242170
Run time 2 hours 12 min 32 sec
CPU time 2 hours 8 min 23 sec
Validate state Valid
Credit 58.11
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.18 MB
Peak swap size 32.63 GB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_190.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_190_1_r1487587189_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_190_1_r1487587189_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 109.274616
     * GNaL_b in INaL: 0.005844
     * Gto_b in Ito: 0.094451
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032371
     * GKs_b in IKs: 0.001798
     * GK1_b in IK1: 0.173123
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 65.731608
     * GKb_b in IKb: 0.003887
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019211
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10561152, states[0] = 5.806828, states[40]= 0.004646
Saving checkpoint... 
Iteration: 26964325, states[0] = -95.091091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43200002, states[0] = -94.883655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58610387, states[0] = -29.814496, states[40]= 0.000489
Saving checkpoint... 
Iteration: 69615928, states[0] = -34.875547, states[40]= 0.000273
Saving checkpoint... 
Iteration: 86035758, states[0] = 16.153296, states[40]= 0.005233
Saving checkpoint... 
Iteration: 102446353, states[0] = -95.064692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118863538, states[0] = -95.039478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135310544, states[0] = -95.009913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151491216, states[0] = -95.069838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167664930, states[0] = -93.624794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177967005, states[0] = -95.065992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193183621, states[0] = -94.830559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207639794, states[0] = -59.405345, states[40]= 0.000006
Saving checkpoint... 
Iteration: 222690230, states[0] = -94.846946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238270408, states[0] = -94.974380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253541680, states[0] = 14.216607, states[40]= 0.004983
Saving checkpoint... 
Iteration: 267347960, states[0] = -95.030732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281378281, states[0] = -95.043529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295482475, states[0] = -95.067945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308884696, states[0] = -95.045775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323643324, states[0] = -63.646646, states[40]= 0.000003
Saving checkpoint... 
Iteration: 339138588, states[0] = -57.999425, states[40]= 0.000008
Saving checkpoint... 
Iteration: 354554006, states[0] = 9.659322, states[40]= 0.004808
Saving checkpoint... 
Iteration: 368925004, states[0] = -95.057300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381470539, states[0] = -95.066111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396201255, states[0] = -94.870092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411173084, states[0] = -94.728377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426572454, states[0] = 1.479563, states[40]= 0.004393
Saving checkpoint... 
Iteration: 440477925, states[0] = -95.067179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455687614, states[0] = -94.840657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470390169, states[0] = -95.047484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486150536, states[0] = -73.810577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 501829024, states[0] = -95.020441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517246965, states[0] = -94.946422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531968442, states[0] = -95.065669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547469035, states[0] = -95.065751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563211855, states[0] = -94.890608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579406462, states[0] = -95.052349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589095000, states[0] = -14.921035, states[40]= 0.001476
Saving checkpoint... 
Iteration: 604058846, states[0] = 7.721814, states[40]= 0.004765
Saving checkpoint... 
Iteration: 619754961, states[0] = -94.956548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634777069, states[0] = -94.980767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644584507, states[0] = -6.023737, states[40]= 0.003169
Saving checkpoint... 
Iteration: 659316015, states[0] = -95.012235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674576483, states[0] = -0.736744, states[40]= 0.004124
Saving checkpoint... 
Iteration: 689420763, states[0] = -95.056036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704676652, states[0] = -94.792411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717973784, states[0] = -95.066359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732740001, states[0] = -94.936673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747731872, states[0] = -94.924585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763093483, states[0] = -13.537392, states[40]= 0.001681
Saving checkpoint... 
Iteration: 777998556, states[0] = -95.069658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793282019, states[0] = -94.985366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809291294, states[0] = -94.993581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819817129, states[0] = -95.012849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835108771, states[0] = -27.697647, states[40]= 0.000593
Saving checkpoint... 
Iteration: 850412633, states[0] = -95.053835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865516748, states[0] = 20.762107, states[40]= 0.013325
Saving checkpoint... 
Iteration: 881041016, states[0] = 14.449403, states[40]= 0.005003
Saving checkpoint... 
Iteration: 897138603, states[0] = -58.015817, states[40]= 0.000008
Saving checkpoint... 
Iteration: 913517474, states[0] = 20.660818, states[40]= 0.012024
Saving checkpoint... 
Iteration: 930084307, states[0] = -5.874791, states[40]= 0.003201
Saving checkpoint... 
Iteration: 940770156, states[0] = -94.973541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955213759, states[0] = -94.893836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970610608, states[0] = -29.411170, states[40]= 0.000510
Saving checkpoint... 
Iteration: 987184632, states[0] = -94.832666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003411813, states[0] = -95.053503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020098592, states[0] = -18.242296, states[40]= 0.001108
Saving checkpoint... 
Iteration: 1036972588, states[0] = -95.065941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053803564, states[0] = -95.003171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070638590, states[0] = -58.000723, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1087423280, states[0] = -95.056354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104548221, states[0] = 11.857248, states[40]= 0.004859
Saving checkpoint... 
Iteration: 1121577602, states[0] = -1.397050, states[40]= 0.004028
Saving checkpoint... 
Iteration: 1138643006, states[0] = -63.249095, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1146532786, states[0] = 17.145653, states[40]= 0.005446
Saving checkpoint... 
Iteration: 1163225641, states[0] = -94.914338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179158448, states[0] = -87.671915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195699112, states[0] = -94.865113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212158762, states[0] = -88.150662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229191989, states[0] = -94.850004, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_190.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_190_1_r1487587189_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_190_1_r1487587189_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 109.274616
     * GNaL_b in INaL: 0.005844
     * Gto_b in Ito: 0.094451
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032371
     * GKs_b in IKs: 0.001798
     * GK1_b in IK1: 0.173123
     * Gncx_b in INaCa_i: 0.000971
     * Pnak_b in INaK: 65.731608
     * GKb_b in IKb: 0.003887
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019211
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1229191989
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.850004 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1240534695, states[0] = 16.555312, states[40]= 0.005302
Saving checkpoint... 
Iteration: 1257793041, states[0] = -94.994713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274621774, states[0] = -40.067877, states[40]= 0.000133
Saving checkpoint... 
Iteration: 1291098209, states[0] = -17.886444, states[40]= 0.001139
Saving checkpoint... 
Iteration: 1301685163, states[0] = -94.833872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312731636, states[0] = -94.923798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320986177, states[0] = -95.067682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336036546, states[0] = 15.960675, states[40]= 0.005190
Saving checkpoint... 
Iteration: 1346051100, states[0] = 10.777688, states[40]= 0.004831
Saving checkpoint... 
Iteration: 1362323643, states[0] = -95.016579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374886228, states[0] = -95.045500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391106212, states[0] = -25.317786, states[40]= 0.000706
Saving checkpoint... 
Iteration: 1407392344, states[0] = -95.047493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424712543, states[0] = -94.891242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441079191, states[0] = -2.373705, states[40]= 0.003871
Saving checkpoint... 
Iteration: 1457449387, states[0] = -95.061671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473514861, states[0] = 21.004485, states[40]= 0.018249
Saving checkpoint... 
Iteration: 1489653699, states[0] = -79.252662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504813013, states[0] = 22.087468, states[40]= 0.028908
Saving checkpoint... 
Iteration: 1520700539, states[0] = -3.064029, states[40]= 0.000118
Saving checkpoint... 
Iteration: 1530368243, states[0] = -4.029541, states[40]= 0.004017
Saving checkpoint... 
Iteration: 1546039011, states[0] = -92.032444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559120364, states[0] = 19.919113, states[40]= 0.010134
Saving checkpoint... 
Iteration: 1573867904, states[0] = -4.518864, states[40]= 0.003926
Saving checkpoint... 
Iteration: 1588667600, states[0] = -95.139539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604246405, states[0] = -94.886480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619494822, states[0] = -32.728161, states[40]= 0.000349
Saving checkpoint... 
Iteration: 1631612475, states[0] = -95.237169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647838445, states[0] = -95.274361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664326751, states[0] = -95.259364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680773924, states[0] = -95.159755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697140817, states[0] = 11.623661, states[40]= 0.005848
Saving checkpoint... 
Iteration: 1713358803, states[0] = 1.846464, states[40]= 0.005021
Saving checkpoint... 
Iteration: 1723391231, states[0] = -95.199026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739129579, states[0] = 16.598238, states[40]= 0.006804
Saving checkpoint... 
Iteration: 1753468077, states[0] = -95.305730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768802117, states[0] = 43.916550, states[40]= 0.085623
Saving checkpoint... 
Iteration: 1783654351, states[0] = -95.095334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798475064, states[0] = -95.311642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814130514, states[0] = -52.610285, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1829157755, states[0] = -89.936486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844181391, states[0] = -94.841560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859039712, states[0] = 14.711628, states[40]= 0.005045
Saving checkpoint... 
Iteration: 1869221144, states[0] = -94.915170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884511437, states[0] = 21.423553, states[40]= 0.037743
Saving checkpoint... 
Iteration: 1899177334, states[0] = -94.803462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913938080, states[0] = -95.061369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929179222, states[0] = -94.813215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944821884, states[0] = -95.015957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954593699, states[0] = -13.775564, states[40]= 0.001643
Saving checkpoint... 
Iteration: 1969556533, states[0] = 8.651070, states[40]= 0.004788
Saving checkpoint... 
Iteration: 1983897328, states[0] = -95.048867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998687597, states[0] = -94.839597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014500112, states[0] = -81.309254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024220376, states[0] = -94.904849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039261320, states[0] = -94.963021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055409359, states[0] = -95.052026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071710136, states[0] = -94.886205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088201263, states[0] = -94.868785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098838377, states[0] = -95.024410, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.944666
 - CaMKt in component CaMK (millimolar): 0.007297
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.745890
 - nass in component intracellular_ions (millimolar): 6.745952
 - ki in component intracellular_ions (millimolar): 145.225850
 - kss in component intracellular_ions (millimolar): 145.225830
 - cansr in component intracellular_ions (millimolar): 1.333876
 - cajsr in component intracellular_ions (millimolar): 1.295613
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003603
 - hf in component INa (dimensionless): 0.880742
 - hs in component INa (dimensionless): 0.880737
 - j in component INa (dimensionless): 0.880708
 - hsp in component INa (dimensionless): 0.727227
 - jp in component INa (dimensionless): 0.880688
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711110
 - hLp in component INaL (dimensionless): 0.453526
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.621606
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.697006
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937328
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001682
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.323930
 - xs1 in component IKs (dimensionless): 0.239915
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997326
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:01:53 (22750): called boinc_finish(0)

</stderr_txt>
]]>


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