𝕏

Task 55446106

Name HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_843_0
Workunit 26329228
Created 30 Jun 2024, 12:51:05 UTC
Sent 30 Jun 2024, 14:23:16 UTC
Report deadline 3 Jul 2024, 23:59:16 UTC
Received 1 Jul 2024, 4:20:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214243
Run time 3 hours 1 min 44 sec
CPU time 2 hours 32 min 31 sec
Validate state Valid
Credit 59.82
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 1.82 MB
Peak swap size 3.99 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_843.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_843_0_r1287315759_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_843_0_r1287315759_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.979480
     * GNaL_b in INaL: 0.004694
     * Gto_b in Ito: 0.087196
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.031841
     * GKs_b in IKs: 0.002115
     * GK1_b in IK1: 0.171074
     * Gncx_b in INaCa_i: 0.000973
     * Pnak_b in INaK: 67.732956
     * GKb_b in IKb: 0.003891
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034541
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11334453, states[0] = -94.971474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23101723, states[0] = -28.547628, states[40]= 0.000501
Saving checkpoint... 
Iteration: 34800578, states[0] = -94.916983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45875960, states[0] = -94.947434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57596252, states[0] = -21.882418, states[40]= 0.000841
Saving checkpoint... 
Iteration: 69189571, states[0] = -94.755807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80653277, states[0] = -88.674525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92410781, states[0] = -94.944707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104040098, states[0] = 13.658093, states[40]= 0.005300
Saving checkpoint... 
Iteration: 115764883, states[0] = -94.863717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127531146, states[0] = 16.893271, states[40]= 0.006011
Saving checkpoint... 
Iteration: 138764922, states[0] = -94.862678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150477345, states[0] = -94.953496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162049522, states[0] = 9.967047, states[40]= 0.005002
Saving checkpoint... 
Iteration: 173756022, states[0] = -94.852399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185557247, states[0] = 6.680646, states[40]= 0.004853
Saving checkpoint... 
Iteration: 197076084, states[0] = -3.394003, states[40]= 0.003752
Saving checkpoint... 
Iteration: 208896566, states[0] = -94.936767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220582382, states[0] = -8.177216, states[40]= 0.002756
Saving checkpoint... 
Iteration: 232239244, states[0] = -94.831476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244123961, states[0] = -48.614356, states[40]= 0.000033
Saving checkpoint... 
Iteration: 255622087, states[0] = -46.645364, states[40]= 0.000045
Saving checkpoint... 
Iteration: 267455501, states[0] = -94.949455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278940225, states[0] = -94.946758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290615211, states[0] = -39.625802, states[40]= 0.000129
Saving checkpoint... 
Iteration: 302299273, states[0] = -94.891174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313678088, states[0] = -94.720107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325439999, states[0] = -94.946672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336870487, states[0] = -94.928182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348479403, states[0] = -94.952877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360165458, states[0] = -94.512935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371544836, states[0] = 11.866061, states[40]= 0.005118
Saving checkpoint... 
Iteration: 383324168, states[0] = -94.907057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394934944, states[0] = -94.945646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406519933, states[0] = 20.069239, states[40]= 0.009932
Saving checkpoint... 
Iteration: 418249922, states[0] = -94.844777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429665413, states[0] = -94.510077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441475037, states[0] = -94.952234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453120992, states[0] = -45.503139, states[40]= 0.000053
Saving checkpoint... 
Iteration: 464705782, states[0] = -94.778442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476448152, states[0] = -94.948053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487774972, states[0] = -94.871137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499593698, states[0] = -18.676586, states[40]= 0.001068
Saving checkpoint... 
Iteration: 511149289, states[0] = -81.248912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522575939, states[0] = -3.287718, states[40]= 0.003772
Saving checkpoint... 
Iteration: 534186693, states[0] = -94.740766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545607463, states[0] = -32.021152, states[40]= 0.000356
Saving checkpoint... 
Iteration: 557409187, states[0] = -94.939777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569279278, states[0] = -94.874979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580782066, states[0] = -94.877404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592502242, states[0] = 43.373534, states[40]= 0.097870
Saving checkpoint... 
Iteration: 603961686, states[0] = -94.950195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615841758, states[0] = -94.916039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627620891, states[0] = -45.398298, states[40]= 0.000054
Saving checkpoint... 
Iteration: 639066568, states[0] = 2.240765, states[40]= 0.004550
Saving checkpoint... 
Iteration: 650766004, states[0] = -94.862349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662288486, states[0] = -94.882696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674154083, states[0] = -89.113769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685860587, states[0] = -94.924197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697370660, states[0] = -94.928009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709242590, states[0] = -94.835484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720838344, states[0] = -94.914319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732641737, states[0] = -69.128532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744367444, states[0] = -94.926799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755964078, states[0] = -94.950462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767793971, states[0] = -94.886928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779165730, states[0] = -94.528714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790928406, states[0] = -94.944056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802612690, states[0] = -37.126700, states[40]= 0.000184
Saving checkpoint... 
Iteration: 814240241, states[0] = -94.832351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826190675, states[0] = -94.748876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837696756, states[0] = -94.761061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849454326, states[0] = -94.948863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861023666, states[0] = 19.151789, states[40]= 0.007676
Saving checkpoint... 
Iteration: 872739953, states[0] = -94.831933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884661824, states[0] = -94.096143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896119490, states[0] = -43.953113, states[40]= 0.000068
Saving checkpoint... 
Iteration: 907993478, states[0] = -94.954231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919530407, states[0] = 17.155336, states[40]= 0.006109
Saving checkpoint... 
Iteration: 931716140, states[0] = -94.796302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943494651, states[0] = -94.954341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954964390, states[0] = -94.950381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966691879, states[0] = -94.751240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978190042, states[0] = -94.747478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989894533, states[0] = -94.935546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001835126, states[0] = -94.912529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013465345, states[0] = -94.950486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025379126, states[0] = -94.930738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036909545, states[0] = -94.939558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048743637, states[0] = -94.836606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060397782, states[0] = -94.936424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071999382, states[0] = -94.954779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083889753, states[0] = -94.934074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095506187, states[0] = 25.471342, states[40]= 0.126446
Saving checkpoint... 
Iteration: 1107524091, states[0] = 19.038449, states[40]= 0.007515
Saving checkpoint... 
Iteration: 1119303486, states[0] = -94.893621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131023143, states[0] = 19.288904, states[40]= 0.007893
Saving checkpoint... 
Iteration: 1142863896, states[0] = -94.925198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154320993, states[0] = -94.904737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166242645, states[0] = -94.835259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177796922, states[0] = -94.888881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189520736, states[0] = 19.883939, states[40]= 0.009274
Saving checkpoint... 
Iteration: 1201302131, states[0] = -94.892622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212834112, states[0] = -94.911876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224749357, states[0] = -94.843578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236360072, states[0] = -94.923637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248151424, states[0] = -85.022812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260087366, states[0] = -12.607796, states[40]= 0.001865
Saving checkpoint... 
Iteration: 1271641181, states[0] = -68.366200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1283520974, states[0] = 19.827748, states[40]= 0.009101
Saving checkpoint... 
Iteration: 1295120337, states[0] = -44.824750, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1307091608, states[0] = -16.650416, states[40]= 0.001273
Saving checkpoint... 
Iteration: 1318922892, states[0] = -94.942525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330571034, states[0] = -0.209112, states[40]= 0.004268
Saving checkpoint... 
Iteration: 1342423378, states[0] = -94.942618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353904360, states[0] = -94.938021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365817902, states[0] = -94.902771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377419999, states[0] = -94.941838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388974048, states[0] = -94.951489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400722967, states[0] = -94.807063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412166048, states[0] = -94.545429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424188537, states[0] = -94.744070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435939193, states[0] = -94.945800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447733796, states[0] = -94.823148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459576543, states[0] = -3.701609, states[40]= 0.003694
Saving checkpoint... 
Iteration: 1471288186, states[0] = -94.881932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483270823, states[0] = -94.866576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494879474, states[0] = -94.930551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506639812, states[0] = 11.978001, states[40]= 0.006082
Saving checkpoint... 
Iteration: 1518315768, states[0] = 21.455090, states[40]= 0.018672
Saving checkpoint... 
Iteration: 1530002936, states[0] = 39.107062, states[40]= 0.098595
Saving checkpoint... 
Iteration: 1541885671, states[0] = -95.071597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553387357, states[0] = -95.201836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565252018, states[0] = -94.990703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576803785, states[0] = 34.037760, states[40]= 0.123237
Saving checkpoint... 
Iteration: 1588757677, states[0] = -95.186915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600578625, states[0] = -19.059549, states[40]= 0.001131
Saving checkpoint... 
Iteration: 1612171027, states[0] = -95.200448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623987562, states[0] = -29.192448, states[40]= 0.000476
Saving checkpoint... 
Iteration: 1635258191, states[0] = -95.190464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647082037, states[0] = -23.025397, states[40]= 0.000810
Saving checkpoint... 
Iteration: 1658803246, states[0] = -47.121885, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1670500365, states[0] = -43.737996, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1682409996, states[0] = 23.177287, states[40]= 0.054481
Saving checkpoint... 
Iteration: 1693866909, states[0] = -6.644717, states[40]= 0.003454
Saving checkpoint... 
Iteration: 1705767137, states[0] = -95.198987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717222329, states[0] = 18.953487, states[40]= 0.009557
Saving checkpoint... 
Iteration: 1728948630, states[0] = 6.404531, states[40]= 0.005563
Saving checkpoint... 
Iteration: 1740778074, states[0] = -95.073693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751993972, states[0] = -95.218367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763620172, states[0] = -95.148107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775096133, states[0] = -95.219691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786915996, states[0] = -63.001886, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1798832103, states[0] = 14.911578, states[40]= 0.006845
Saving checkpoint... 
Iteration: 1810406740, states[0] = -94.982713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822040904, states[0] = 12.873880, states[40]= 0.005257
Saving checkpoint... 
Iteration: 1833599758, states[0] = -26.048107, states[40]= 0.000629
Saving checkpoint... 
Iteration: 1845418671, states[0] = -94.957998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857212265, states[0] = -94.801298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868719073, states[0] = -94.809191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880648837, states[0] = -81.273167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892217041, states[0] = -94.801478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904240824, states[0] = -94.835390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915786896, states[0] = -94.882671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927295198, states[0] = -94.888571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939030610, states[0] = 17.075750, states[40]= 0.006080
Saving checkpoint... 
Iteration: 1950529727, states[0] = 17.365206, states[40]= 0.006205
Saving checkpoint... 
Iteration: 1962515327, states[0] = 21.023364, states[40]= 0.017920
Saving checkpoint... 
Iteration: 1974151926, states[0] = -85.918001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985868417, states[0] = -94.926577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1997840475, states[0] = -94.914672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009444363, states[0] = -94.946474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021303462, states[0] = -94.893066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032739023, states[0] = -94.829962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044382838, states[0] = -94.931295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056053670, states[0] = 8.241699, states[40]= 0.004923
Saving checkpoint... 
Iteration: 2067619214, states[0] = -43.670875, states[40]= 0.000071
Saving checkpoint... 
Iteration: 2079511131, states[0] = 21.953623, states[40]= 0.041773
Saving checkpoint... 
Iteration: 2090994928, states[0] = -94.953595, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.830018
 - CaMKt in component CaMK (millimolar): 0.006886
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.716613
 - nass in component intracellular_ions (millimolar): 6.716672
 - ki in component intracellular_ions (millimolar): 145.260566
 - kss in component intracellular_ions (millimolar): 145.260547
 - cansr in component intracellular_ions (millimolar): 1.313572
 - cajsr in component intracellular_ions (millimolar): 1.276329
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003645
 - hf in component INa (dimensionless): 0.878749
 - hs in component INa (dimensionless): 0.878744
 - j in component INa (dimensionless): 0.878717
 - hsp in component INa (dimensionless): 0.723477
 - jp in component INa (dimensionless): 0.878699
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709449
 - hLp in component INaL (dimensionless): 0.454214
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.627282
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.703727
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.941619
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999904
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001613
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.324325
 - xs1 in component IKs (dimensionless): 0.228286
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997356
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:53:35 (50607): called boinc_finish(0)

</stderr_txt>
]]>


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