𝕏

Task 55445849

Name HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_802_1
Workunit 26329099
Created 30 Jun 2024, 12:50:55 UTC
Sent 30 Jun 2024, 14:23:16 UTC
Report deadline 3 Jul 2024, 23:59:16 UTC
Received 3 Jul 2024, 7:13:44 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226324
Run time 2 hours 45 min 16 sec
CPU time 2 hours 30 min 45 sec
Validate state Valid
Credit 60.37
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_802.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_802_1_r1228282386_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630145053121262_ORdGradInc_k_25-Pueyo_APDR-conf_802_1_r1228282386_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 112.177087
     * GNaL_b in INaL: 0.006003
     * Gto_b in Ito: 0.099228
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030424
     * GKs_b in IKs: 0.001891
     * GK1_b in IK1: 0.175834
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 65.988121
     * GKb_b in IKb: 0.003729
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029747
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14750042, states[0] = -94.899795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32476433, states[0] = -94.995514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50791628, states[0] = -94.914491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67270902, states[0] = -94.890851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83401308, states[0] = -94.965810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99230118, states[0] = -94.833569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115059032, states[0] = 8.851074, states[40]= 0.004716
Saving checkpoint... 
Iteration: 130419121, states[0] = -94.967924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146773426, states[0] = -94.888065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160869567, states[0] = -94.951563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176162706, states[0] = -83.898186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191912080, states[0] = -94.965296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207045432, states[0] = 13.800681, states[40]= 0.004779
Saving checkpoint... 
Iteration: 224692987, states[0] = -94.760958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239241884, states[0] = -94.848967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255613545, states[0] = -27.688894, states[40]= 0.000636
Saving checkpoint... 
Iteration: 272387110, states[0] = -94.957569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288492157, states[0] = -94.980171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304046465, states[0] = 13.447947, states[40]= 0.004768
Saving checkpoint... 
Iteration: 316631379, states[0] = -44.111378, states[40]= 0.000079
Saving checkpoint... 
Iteration: 328973330, states[0] = -94.977528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341348539, states[0] = -94.941751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354837018, states[0] = -94.935787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367371719, states[0] = -94.951878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380251364, states[0] = -94.861715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392687882, states[0] = -94.746163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405259545, states[0] = -94.871868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418434582, states[0] = -94.970398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430970399, states[0] = -94.976995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443441402, states[0] = -94.971812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456546436, states[0] = 13.458069, states[40]= 0.004768
Saving checkpoint... 
Iteration: 470019567, states[0] = 20.636129, states[40]= 0.009055
Saving checkpoint... 
Iteration: 483691421, states[0] = -94.756831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497715893, states[0] = -94.806601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511140410, states[0] = -53.343441, states[40]= 0.000018
Saving checkpoint... 
Iteration: 524278223, states[0] = -94.892032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537279664, states[0] = -94.893429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550347067, states[0] = -94.940858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565076867, states[0] = 0.982801, states[40]= 0.004288
Saving checkpoint... 
Iteration: 580361681, states[0] = -94.947587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594429909, states[0] = -94.969221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607493206, states[0] = -94.980039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622189205, states[0] = -94.750471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636775040, states[0] = -94.888758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649291379, states[0] = -94.904045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662411816, states[0] = -94.964701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674972806, states[0] = -94.977170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687426564, states[0] = -94.968377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700079980, states[0] = -0.709891, states[40]= 0.004079
Saving checkpoint... 
Iteration: 714604113, states[0] = -19.331312, states[40]= 0.001036
Saving checkpoint... 
Iteration: 727907411, states[0] = -94.963442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740057536, states[0] = 9.454924, states[40]= 0.004722
Saving checkpoint... 
Iteration: 752751247, states[0] = -94.861264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765337819, states[0] = -94.935894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778272053, states[0] = -94.885561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791709457, states[0] = -94.794358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804717529, states[0] = -94.809309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817280136, states[0] = -94.893661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829887921, states[0] = -94.957384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842607369, states[0] = -22.219077, states[40]= 0.000882
Saving checkpoint... 
Iteration: 855322331, states[0] = -94.926759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867972733, states[0] = -94.977005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880648460, states[0] = -62.257896, states[40]= 0.000004
Saving checkpoint... 
Iteration: 893625916, states[0] = -38.877322, states[40]= 0.000170
Saving checkpoint... 
Iteration: 906345196, states[0] = -94.939639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919258153, states[0] = -94.869784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932022076, states[0] = 20.251718, states[40]= 0.007381
Saving checkpoint... 
Iteration: 944768086, states[0] = -94.881183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957465931, states[0] = -94.975867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970133471, states[0] = -46.188005, states[40]= 0.000057
Saving checkpoint... 
Iteration: 984241904, states[0] = -94.848360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997148085, states[0] = -61.816880, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1009867694, states[0] = -94.949760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022083513, states[0] = -2.814228, states[40]= 0.003751
Saving checkpoint... 
Iteration: 1034814494, states[0] = -94.921474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047233871, states[0] = -94.836383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059842154, states[0] = -94.937959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072788310, states[0] = -94.901024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085743686, states[0] = -94.850798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098227215, states[0] = -94.825729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110931569, states[0] = -94.969183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123845112, states[0] = -94.939423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136784504, states[0] = -94.897528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149353200, states[0] = -94.943330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161909094, states[0] = -94.963563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174574355, states[0] = 2.258454, states[40]= 0.004413
Saving checkpoint... 
Iteration: 1187557022, states[0] = 9.649758, states[40]= 0.004723
Saving checkpoint... 
Iteration: 1200173398, states[0] = -94.108003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212810222, states[0] = -94.918356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225616310, states[0] = -30.147279, states[40]= 0.000510
Saving checkpoint... 
Iteration: 1238464711, states[0] = -94.975444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251145519, states[0] = -58.884516, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1263700687, states[0] = -94.776665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276429278, states[0] = -94.968534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288652896, states[0] = -67.821985, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1301262971, states[0] = -94.875163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313642523, states[0] = -55.599148, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1326182168, states[0] = -94.705456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339037143, states[0] = 16.508521, states[40]= 0.004992
Saving checkpoint... 
Iteration: 1352319227, states[0] = -94.924373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365448400, states[0] = -94.972457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378190864, states[0] = -94.754646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390574024, states[0] = 2.421318, states[40]= 0.004427
Saving checkpoint... 
Iteration: 1402852878, states[0] = -94.942977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417413559, states[0] = -94.964563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431063982, states[0] = 6.910060, states[40]= 0.004675
Saving checkpoint... 
Iteration: 1444324452, states[0] = -94.927612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457272383, states[0] = -94.885363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471089244, states[0] = -6.738069, states[40]= 0.002981
Saving checkpoint... 
Iteration: 1485702957, states[0] = -94.781075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499353928, states[0] = -94.943389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512559801, states[0] = -95.162980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526457286, states[0] = 5.006491, states[40]= 0.005245
Saving checkpoint... 
Iteration: 1539387236, states[0] = -19.617194, states[40]= 0.001094
Saving checkpoint... 
Iteration: 1552197593, states[0] = -95.221513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565357115, states[0] = -95.192821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1578749729, states[0] = -94.577376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591912846, states[0] = -47.615674, states[40]= 0.000048
Saving checkpoint... 
Iteration: 1605327318, states[0] = 18.136948, states[40]= 0.006958
Saving checkpoint... 
Iteration: 1618292794, states[0] = -26.363435, states[40]= 0.000679
Saving checkpoint... 
Iteration: 1631280241, states[0] = -95.077381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644566289, states[0] = -95.209383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657658332, states[0] = -95.002512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670654385, states[0] = -95.198120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684404807, states[0] = -95.129192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697214224, states[0] = -49.455173, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1709955903, states[0] = -95.199847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722630530, states[0] = 16.933565, states[40]= 0.006478
Saving checkpoint... 
Iteration: 1735924961, states[0] = -62.621216, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1748189801, states[0] = -23.357496, states[40]= 0.000838
Saving checkpoint... 
Iteration: 1761076369, states[0] = -9.622162, states[40]= 0.002713
Saving checkpoint... 
Iteration: 1773472174, states[0] = -95.058393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786161153, states[0] = -95.205057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798512725, states[0] = 21.871138, states[40]= 0.029300
Saving checkpoint... 
Iteration: 1811658959, states[0] = -83.866389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824519363, states[0] = 20.368351, states[40]= 0.009034
Saving checkpoint... 
Iteration: 1837488869, states[0] = -94.999321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850396156, states[0] = -94.973463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863040554, states[0] = 15.271833, states[40]= 0.004870
Saving checkpoint... 
Iteration: 1875505423, states[0] = 25.299798, states[40]= 0.156796
Saving checkpoint... 
Iteration: 1888159616, states[0] = -78.959513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900675848, states[0] = -94.479776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912843437, states[0] = -94.940136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926003282, states[0] = 33.635259, states[40]= 0.167922
Saving checkpoint... 
Iteration: 1939379183, states[0] = -94.954404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952653824, states[0] = -69.174348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1965896602, states[0] = -94.959675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979037633, states[0] = 16.352383, states[40]= 0.004971
Saving checkpoint... 
Iteration: 1991764739, states[0] = -94.876776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004529119, states[0] = 18.759733, states[40]= 0.005607
Saving checkpoint... 
Iteration: 2018102510, states[0] = -17.911881, states[40]= 0.001142
Saving checkpoint... 
Iteration: 2031468288, states[0] = -94.975381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044790348, states[0] = -94.902007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057974272, states[0] = -94.976244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070626330, states[0] = -39.265516, states[40]= 0.000161
Saving checkpoint... 
Iteration: 2083929714, states[0] = -94.967928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098418996, states[0] = -94.965352, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.855481
 - CaMKt in component CaMK (millimolar): 0.007549
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.786504
 - nass in component intracellular_ions (millimolar): 6.786565
 - ki in component intracellular_ions (millimolar): 145.182980
 - kss in component intracellular_ions (millimolar): 145.182961
 - cansr in component intracellular_ions (millimolar): 1.342015
 - cajsr in component intracellular_ions (millimolar): 1.302908
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003635
 - hf in component INa (dimensionless): 0.879194
 - hs in component INa (dimensionless): 0.879189
 - j in component INa (dimensionless): 0.879160
 - hsp in component INa (dimensionless): 0.724311
 - jp in component INa (dimensionless): 0.879140
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707273
 - hLp in component INaL (dimensionless): 0.446513
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.614748
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.688726
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933362
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999875
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001706
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332581
 - xs1 in component IKs (dimensionless): 0.249299
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997349
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:13:46 (33997): called boinc_finish(0)

</stderr_txt>
]]>


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