𝕏

Task 55445137

Name HuVeMOp_20240630144553171241_ORdGradInc_k_25-Pueyo_APDR-conf_912_0
Workunit 26328746
Created 30 Jun 2024, 12:45:58 UTC
Sent 30 Jun 2024, 14:12:43 UTC
Report deadline 3 Jul 2024, 23:48:43 UTC
Received 30 Jun 2024, 23:05:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 26 min 42 sec
CPU time 1 hours 25 min 31 sec
Validate state Valid
Credit 59.09
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144553171241_ORdGradInc_k_25-Pueyo_APDR-conf_912.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144553171241_ORdGradInc_k_25-Pueyo_APDR-conf_912_0_r777772362_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144553171241_ORdGradInc_k_25-Pueyo_APDR-conf_912_0_r777772362_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.269749
     * GNaL_b in INaL: 0.006912
     * Gto_b in Ito: 0.070196
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030692
     * GKs_b in IKs: 0.001873
     * GK1_b in IK1: 0.160195
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 70.553398
     * GKb_b in IKb: 0.003790
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032186
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12504851, states[0] = 30.375322, states[40]= 0.139861
Saving checkpoint... 
Iteration: 24584466, states[0] = -4.922592, states[40]= 0.003446
Saving checkpoint... 
Iteration: 36617685, states[0] = -33.306734, states[40]= 0.000344
Saving checkpoint... 
Iteration: 48799876, states[0] = -94.801643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60980090, states[0] = -94.862692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73031354, states[0] = 19.662677, states[40]= 0.006115
Saving checkpoint... 
Iteration: 84941140, states[0] = -94.847427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97256273, states[0] = -94.738603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109436392, states[0] = -94.842243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121699713, states[0] = -94.642764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133907451, states[0] = -94.833006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146207537, states[0] = -94.656748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158393686, states[0] = -94.827832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170591153, states[0] = -8.015426, states[40]= 0.002755
Saving checkpoint... 
Iteration: 182813338, states[0] = -94.787970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194491392, states[0] = -94.847933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206618439, states[0] = -32.063082, states[40]= 0.000402
Saving checkpoint... 
Iteration: 218315403, states[0] = -94.789108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230633000, states[0] = -45.813394, states[40]= 0.000057
Saving checkpoint... 
Iteration: 242939275, states[0] = -94.838987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255384081, states[0] = -94.823652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267668483, states[0] = -90.505085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279941038, states[0] = -94.839285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292141039, states[0] = -54.131319, states[40]= 0.000015
Saving checkpoint... 
Iteration: 304325286, states[0] = -94.795442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315967818, states[0] = -94.844161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327644579, states[0] = -57.937917, states[40]= 0.000008
Saving checkpoint... 
Iteration: 339836457, states[0] = -94.802064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352014402, states[0] = 24.182526, states[40]= 0.020369
Saving checkpoint... 
Iteration: 363729196, states[0] = -94.693758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376034246, states[0] = 18.830822, states[40]= 0.005813
Saving checkpoint... 
Iteration: 388829467, states[0] = -94.797955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401262113, states[0] = -94.739925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413717790, states[0] = -94.674223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426051614, states[0] = 12.387919, states[40]= 0.005100
Saving checkpoint... 
Iteration: 438400191, states[0] = -94.828809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450816125, states[0] = -94.789313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462962327, states[0] = -94.843156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474783757, states[0] = -94.762969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486573700, states[0] = 2.860534, states[40]= 0.004605
Saving checkpoint... 
Iteration: 498844301, states[0] = -94.806217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510650338, states[0] = -64.469504, states[40]= 0.000002
Saving checkpoint... 
Iteration: 522615251, states[0] = -29.177331, states[40]= 0.000547
Saving checkpoint... 
Iteration: 534798739, states[0] = -94.776189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547052821, states[0] = 11.914322, states[40]= 0.005082
Saving checkpoint... 
Iteration: 559277323, states[0] = -94.756577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571595088, states[0] = -11.212852, states[40]= 0.002093
Saving checkpoint... 
Iteration: 583774557, states[0] = -94.753705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596123325, states[0] = -36.509222, states[40]= 0.000227
Saving checkpoint... 
Iteration: 608393268, states[0] = -94.826520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620678118, states[0] = -94.331401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632892588, states[0] = -94.826282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645057060, states[0] = 10.223347, states[40]= 0.005025
Saving checkpoint... 
Iteration: 657421622, states[0] = -94.834605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669714994, states[0] = -94.669023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681574671, states[0] = 2.373349, states[40]= 0.004558
Saving checkpoint... 
Iteration: 693483556, states[0] = -94.846277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705608709, states[0] = -23.319571, states[40]= 0.000830
Saving checkpoint... 
Iteration: 718060017, states[0] = 9.012635, states[40]= 0.004982
Saving checkpoint... 
Iteration: 730288093, states[0] = -94.766860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742394670, states[0] = -94.826893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754289417, states[0] = -94.768046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766610884, states[0] = -25.264192, states[40]= 0.000742
Saving checkpoint... 
Iteration: 778940883, states[0] = -94.838927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791076233, states[0] = 1.569522, states[40]= 0.004473
Saving checkpoint... 
Iteration: 802999745, states[0] = -94.848284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815396266, states[0] = -94.827359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827970439, states[0] = -94.844261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840136886, states[0] = -49.773385, states[40]= 0.000031
Saving checkpoint... 
Iteration: 852025573, states[0] = 21.555952, states[40]= 0.007198
Saving checkpoint... 
Iteration: 864105062, states[0] = -20.053384, states[40]= 0.000994
Saving checkpoint... 
Iteration: 876539603, states[0] = 16.938462, states[40]= 0.005444
Saving checkpoint... 
Iteration: 888282804, states[0] = -94.761805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900491343, states[0] = -94.847191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912383159, states[0] = -94.822874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924170322, states[0] = -92.029603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936490018, states[0] = -94.846998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948571977, states[0] = 3.703991, states[40]= 0.004680
Saving checkpoint... 
Iteration: 960936822, states[0] = -94.837956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972824924, states[0] = -94.794798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984939412, states[0] = -94.838495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997068270, states[0] = 5.439030, states[40]= 0.004806
Saving checkpoint... 
Iteration: 1009294149, states[0] = -94.772052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021470896, states[0] = -94.844216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033343893, states[0] = -94.805681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045752932, states[0] = -94.728104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057976807, states[0] = -94.845092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069662550, states[0] = -82.066947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081419335, states[0] = -94.833772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093465821, states[0] = -94.843359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105210265, states[0] = -94.660015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116825996, states[0] = -94.795384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129045394, states[0] = 14.784577, states[40]= 0.005224
Saving checkpoint... 
Iteration: 1140792239, states[0] = -94.770317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153047508, states[0] = 13.978107, states[40]= 0.005173
Saving checkpoint... 
Iteration: 1165211370, states[0] = -94.662045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177629798, states[0] = -42.636152, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1189775030, states[0] = -94.753833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201958201, states[0] = -94.841996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213787236, states[0] = -94.765782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225609592, states[0] = -24.108796, states[40]= 0.000795
Saving checkpoint... 
Iteration: 1238020593, states[0] = 22.850533, states[40]= 0.009478
Saving checkpoint... 
Iteration: 1250225429, states[0] = -94.686973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262495424, states[0] = -94.847486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274704910, states[0] = -94.649697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286891526, states[0] = -94.825537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299076531, states[0] = 1.413289, states[40]= 0.004455
Saving checkpoint... 
Iteration: 1311204748, states[0] = -94.649361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323489841, states[0] = -94.846742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335449598, states[0] = -94.840332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347743986, states[0] = -94.715734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359984196, states[0] = -94.845964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372105090, states[0] = -20.078254, states[40]= 0.000993
Saving checkpoint... 
Iteration: 1384363471, states[0] = -94.814811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396635284, states[0] = -48.123018, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1408809749, states[0] = -94.784201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420549025, states[0] = 13.394248, states[40]= 0.005143
Saving checkpoint... 
Iteration: 1432429189, states[0] = -94.835960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444679015, states[0] = -94.395892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456555155, states[0] = 10.989206, states[40]= 0.005050
Saving checkpoint... 
Iteration: 1468833450, states[0] = -94.799658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480411480, states[0] = -94.831452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492439036, states[0] = -94.838109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504575018, states[0] = -5.191328, states[40]= 0.003678
Saving checkpoint... 
Iteration: 1516618193, states[0] = -50.146784, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1528732942, states[0] = -95.038388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540463991, states[0] = -95.082698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552407130, states[0] = -95.012045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564547126, states[0] = 10.598879, states[40]= 0.005877
Saving checkpoint... 
Iteration: 1576204740, states[0] = 32.176596, states[40]= 0.123655
Saving checkpoint... 
Iteration: 1588438805, states[0] = -95.069597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600678852, states[0] = -94.963475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612892305, states[0] = -24.746760, states[40]= 0.000759
Saving checkpoint... 
Iteration: 1625127711, states[0] = 19.522932, states[40]= 0.007760
Saving checkpoint... 
Iteration: 1637486494, states[0] = -18.789138, states[40]= 0.001176
Saving checkpoint... 
Iteration: 1649352158, states[0] = -95.088981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661266187, states[0] = -94.928887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673589109, states[0] = -94.989205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1685441849, states[0] = 13.097643, states[40]= 0.006145
Saving checkpoint... 
Iteration: 1697777405, states[0] = -9.621742, states[40]= 0.002733
Saving checkpoint... 
Iteration: 1710051190, states[0] = 8.355936, states[40]= 0.005706
Saving checkpoint... 
Iteration: 1722259566, states[0] = -95.097291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733999676, states[0] = -95.130433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746277712, states[0] = -95.114065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758023654, states[0] = 21.104275, states[40]= 0.009011
Saving checkpoint... 
Iteration: 1770384797, states[0] = -17.068139, states[40]= 0.001366
Saving checkpoint... 
Iteration: 1782837077, states[0] = -95.071319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794661552, states[0] = 2.510340, states[40]= 0.005176
Saving checkpoint... 
Iteration: 1807015341, states[0] = 23.627435, states[40]= 0.016596
Saving checkpoint... 
Iteration: 1818795036, states[0] = -94.809007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831002968, states[0] = 38.075833, states[40]= 0.140369
Saving checkpoint... 
Iteration: 1843287651, states[0] = -94.784309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855675080, states[0] = -94.108932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867798392, states[0] = -94.784004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880130672, states[0] = -43.891484, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1892260788, states[0] = -94.741735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904441762, states[0] = -94.841366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916308371, states[0] = -94.784938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928575856, states[0] = 1.728365, states[40]= 0.004492
Saving checkpoint... 
Iteration: 1940406647, states[0] = -94.830793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952622752, states[0] = -36.022554, states[40]= 0.000243
Saving checkpoint... 
Iteration: 1964829980, states[0] = -94.797759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976829395, states[0] = -94.797250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989102712, states[0] = -17.955385, states[40]= 0.001148
Saving checkpoint... 
Iteration: 2001315088, states[0] = -94.787776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013536194, states[0] = 18.155517, states[40]= 0.005654
Saving checkpoint... 
Iteration: 2025561140, states[0] = 8.543429, states[40]= 0.004964
Saving checkpoint... 
Iteration: 2037273002, states[0] = -94.751191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049510732, states[0] = 25.070507, states[40]= 0.042716
Saving checkpoint... 
Iteration: 2061646766, states[0] = -60.353463, states[40]= 0.000005
Saving checkpoint... 
Iteration: 2073931915, states[0] = -94.836167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086119410, states[0] = -32.929966, states[40]= 0.000363
Saving checkpoint... 
Iteration: 2098179333, states[0] = -94.414722, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.723366
 - CaMKt in component CaMK (millimolar): 0.006964
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.620593
 - nass in component intracellular_ions (millimolar): 6.620651
 - ki in component intracellular_ions (millimolar): 145.357954
 - kss in component intracellular_ions (millimolar): 145.357937
 - cansr in component intracellular_ions (millimolar): 1.309568
 - cajsr in component intracellular_ions (millimolar): 1.271140
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003684
 - hf in component INa (dimensionless): 0.876869
 - hs in component INa (dimensionless): 0.876864
 - j in component INa (dimensionless): 0.876834
 - hsp in component INa (dimensionless): 0.719955
 - jp in component INa (dimensionless): 0.876814
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.703622
 - hLp in component INaL (dimensionless): 0.442123
 - a in component Ito (dimensionless): 0.000631
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.613548
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.686300
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.928860
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999863
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001603
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.346961
 - xs1 in component IKs (dimensionless): 0.252016
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997384
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:02:45 (238123): called boinc_finish(0)

</stderr_txt>
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