𝕏

Task 55444847

Name HuVeMOp_20240630144541951441_ORdGradInc_k_25-Pueyo_APDR-conf_626_1
Workunit 26328603
Created 30 Jun 2024, 12:45:48 UTC
Sent 30 Jun 2024, 14:10:03 UTC
Report deadline 3 Jul 2024, 23:46:03 UTC
Received 4 Jul 2024, 14:34:51 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 46 min 17 sec
CPU time 2 hours 19 min 55 sec
Validate state Valid
Credit 59.30
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.34 MB
Peak swap size 5.44 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144541951441_ORdGradInc_k_25-Pueyo_APDR-conf_626.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144541951441_ORdGradInc_k_25-Pueyo_APDR-conf_626_1_r1790664690_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144541951441_ORdGradInc_k_25-Pueyo_APDR-conf_626_1_r1790664690_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.244066
     * GNaL_b in INaL: 0.006037
     * Gto_b in Ito: 0.073194
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034012
     * GKs_b in IKs: 0.001948
     * GK1_b in IK1: 0.151853
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 68.252336
     * GKb_b in IKb: 0.003927
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033333
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11508357, states[0] = 24.906033, states[40]= 0.074712
Saving checkpoint... 
Iteration: 24051591, states[0] = 9.304066, states[40]= 0.005120
Saving checkpoint... 
Iteration: 37159960, states[0] = -94.038368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50708713, states[0] = -94.798806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64051309, states[0] = 10.009173, states[40]= 0.005138
Saving checkpoint... 
Iteration: 77606828, states[0] = -31.654020, states[40]= 0.000368
Saving checkpoint... 
Iteration: 91002373, states[0] = 42.627150, states[40]= 0.102626
Saving checkpoint... 
Iteration: 104402313, states[0] = -94.946627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117866795, states[0] = -94.932836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131202846, states[0] = -94.765628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144809168, states[0] = -94.899797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157507810, states[0] = 25.808151, states[40]= 0.084774
Saving checkpoint... 
Iteration: 171039676, states[0] = 15.069055, states[40]= 0.005553
Saving checkpoint... 
Iteration: 184547765, states[0] = 11.758050, states[40]= 0.005224
Saving checkpoint... 
Iteration: 198082843, states[0] = -7.630480, states[40]= 0.002903
Saving checkpoint... 
Iteration: 211658545, states[0] = -92.836491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225185913, states[0] = -94.727297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238767936, states[0] = -94.862075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250296615, states[0] = -94.888831, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144541951441_ORdGradInc_k_25-Pueyo_APDR-conf_626.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144541951441_ORdGradInc_k_25-Pueyo_APDR-conf_626_1_r1790664690_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144541951441_ORdGradInc_k_25-Pueyo_APDR-conf_626_1_r1790664690_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.244066
     * GNaL_b in INaL: 0.006037
     * Gto_b in Ito: 0.073194
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034012
     * GKs_b in IKs: 0.001948
     * GK1_b in IK1: 0.151853
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 68.252336
     * GKb_b in IKb: 0.003927
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033333
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 250296615
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.888831 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 256413615, states[0] = -94.944947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269587079, states[0] = -11.416067, states[40]= 0.002105
Saving checkpoint... 
Iteration: 280340003, states[0] = -94.917157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282629052, states[0] = -54.934022, states[40]= 0.000012
Saving checkpoint... 
Iteration: 285871690, states[0] = -94.931485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294607455, states[0] = -31.725351, states[40]= 0.000365
Saving checkpoint... 
Iteration: 306734076, states[0] = -94.818378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318106368, states[0] = -30.627446, states[40]= 0.000412
Saving checkpoint... 
Iteration: 328703114, states[0] = -94.763831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342170763, states[0] = -94.639254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354994869, states[0] = -94.959649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367509010, states[0] = 24.965161, states[40]= 0.065125
Saving checkpoint... 
Iteration: 382185407, states[0] = -94.725861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396922571, states[0] = -94.947052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411789041, states[0] = -94.882334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423277588, states[0] = -94.871774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435528321, states[0] = 19.255349, states[40]= 0.006805
Saving checkpoint... 
Iteration: 440826773, states[0] = -94.909628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449174785, states[0] = -94.686365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462430160, states[0] = -94.948772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476998452, states[0] = -94.960002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492020414, states[0] = 21.618384, states[40]= 0.010045
Saving checkpoint... 
Iteration: 506992601, states[0] = -94.959284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521970562, states[0] = -94.956246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536250918, states[0] = -94.841783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551195742, states[0] = -94.748574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565909097, states[0] = -94.943510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580976539, states[0] = -94.957099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595943553, states[0] = -94.951509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611042023, states[0] = 14.136629, states[40]= 0.005431
Saving checkpoint... 
Iteration: 626065289, states[0] = 3.771388, states[40]= 0.004760
Saving checkpoint... 
Iteration: 639934413, states[0] = -94.949604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653969123, states[0] = -94.955951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668937012, states[0] = -94.950139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684014748, states[0] = 23.023190, states[40]= 0.020114
Saving checkpoint... 
Iteration: 698254960, states[0] = -94.846768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711947239, states[0] = -94.952157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726981425, states[0] = -94.957705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741443550, states[0] = -94.951426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756499008, states[0] = -94.959909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771560006, states[0] = 6.353181, states[40]= 0.004937
Saving checkpoint... 
Iteration: 786629283, states[0] = -55.196277, states[40]= 0.000011
Saving checkpoint... 
Iteration: 801578203, states[0] = -3.974427, states[40]= 0.003681
Saving checkpoint... 
Iteration: 816613181, states[0] = -37.560870, states[40]= 0.000173
Saving checkpoint... 
Iteration: 831616312, states[0] = -40.828685, states[40]= 0.000108
Saving checkpoint... 
Iteration: 846725360, states[0] = -94.804232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861358191, states[0] = -94.925556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876379714, states[0] = -94.934121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891392375, states[0] = -94.938397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906466119, states[0] = -94.955338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921487786, states[0] = -94.958443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935690321, states[0] = -94.736728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950560197, states[0] = 6.263322, states[40]= 0.004931
Saving checkpoint... 
Iteration: 961435587, states[0] = -94.949674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974550106, states[0] = 10.772206, states[40]= 0.005164
Saving checkpoint... 
Iteration: 988806117, states[0] = -94.895642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003492371, states[0] = -94.958976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018435238, states[0] = -94.949567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033404012, states[0] = -94.941829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048277462, states[0] = -94.871298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062978571, states[0] = -94.957118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076250777, states[0] = -94.841296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083259876, states[0] = -94.852449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091142368, states[0] = -71.362640, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1104277933, states[0] = -94.871725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118388479, states[0] = -94.937005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132901653, states[0] = -94.941092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147802634, states[0] = -94.892958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162671105, states[0] = -94.644793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177498058, states[0] = -94.959562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192454632, states[0] = -94.953246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207434340, states[0] = -94.949269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222340767, states[0] = -94.916997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237301238, states[0] = -94.891841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252230850, states[0] = -94.812848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267213805, states[0] = -94.783820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282188650, states[0] = -94.732828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297095089, states[0] = -19.292052, states[40]= 0.001019
Saving checkpoint... 
Iteration: 1311632987, states[0] = -59.483261, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1326174962, states[0] = -94.687108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340700225, states[0] = -94.757413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355570560, states[0] = 0.930502, states[40]= 0.004473
Saving checkpoint... 
Iteration: 1369987182, states[0] = -94.958113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384867286, states[0] = -94.929100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399808996, states[0] = -94.897488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414599631, states[0] = -23.852532, states[40]= 0.000733
Saving checkpoint... 
Iteration: 1429288308, states[0] = -94.881120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444074813, states[0] = -1.653624, states[40]= 0.004103
Saving checkpoint... 
Iteration: 1458860156, states[0] = -94.926078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473725237, states[0] = -94.803673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488689267, states[0] = -94.734087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502500840, states[0] = -39.932398, states[40]= 0.000118
Saving checkpoint... 
Iteration: 1515829574, states[0] = -95.151083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530503759, states[0] = -95.126147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1545278378, states[0] = -95.230933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560090942, states[0] = -31.793848, states[40]= 0.000364
Saving checkpoint... 
Iteration: 1574835477, states[0] = -91.928276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589601744, states[0] = -95.149335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604326054, states[0] = -95.191023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619102688, states[0] = 41.296373, states[40]= 0.092358
Saving checkpoint... 
Iteration: 1633977346, states[0] = -95.101158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648420437, states[0] = -95.185031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657835479, states[0] = 14.372572, states[40]= 0.006712
Saving checkpoint... 
Iteration: 1672434365, states[0] = -95.205023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686251919, states[0] = -95.225924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700576229, states[0] = -95.099455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714306199, states[0] = -50.660800, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1728822771, states[0] = -95.189152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1740375644, states[0] = -14.804031, states[40]= 0.001713
Saving checkpoint... 
Iteration: 1754522753, states[0] = -73.223613, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1768888904, states[0] = -30.056739, states[40]= 0.000439
Saving checkpoint... 
Iteration: 1783763701, states[0] = -95.237936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798684545, states[0] = -95.118889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813354585, states[0] = -94.974778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1828212175, states[0] = -94.815239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843094571, states[0] = -19.924703, states[40]= 0.000972
Saving checkpoint... 
Iteration: 1858044647, states[0] = 12.858834, states[40]= 0.005326
Saving checkpoint... 
Iteration: 1872945849, states[0] = -94.960614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887763674, states[0] = -94.862494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901900371, states[0] = -94.944281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916749462, states[0] = -94.841741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931700385, states[0] = -94.759087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946632705, states[0] = -59.229583, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1961339921, states[0] = -94.916808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976273426, states[0] = -94.867167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991197461, states[0] = -94.751607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006114634, states[0] = -39.078702, states[40]= 0.000139
Saving checkpoint... 
Iteration: 2020929737, states[0] = -94.947878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035847472, states[0] = -94.919953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050789823, states[0] = -94.882088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065701727, states[0] = -94.760035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080625476, states[0] = -50.869716, states[40]= 0.000023
Saving checkpoint... 
Iteration: 2095385227, states[0] = -94.935328, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.835106
 - CaMKt in component CaMK (millimolar): 0.006647
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.638182
 - nass in component intracellular_ions (millimolar): 6.638241
 - ki in component intracellular_ions (millimolar): 145.343255
 - kss in component intracellular_ions (millimolar): 145.343236
 - cansr in component intracellular_ions (millimolar): 1.297565
 - cajsr in component intracellular_ions (millimolar): 1.260595
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003643
 - hf in component INa (dimensionless): 0.878838
 - hs in component INa (dimensionless): 0.878833
 - j in component INa (dimensionless): 0.878804
 - hsp in component INa (dimensionless): 0.723643
 - jp in component INa (dimensionless): 0.878785
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709602
 - hLp in component INaL (dimensionless): 0.454383
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.627356
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.703054
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937842
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999897
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001552
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330989
 - xs1 in component IKs (dimensionless): 0.232444
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997355
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:34:19 (6816): called boinc_finish(0)

</stderr_txt>
]]>


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