𝕏

Task 55444825

Name HuVeMOp_20240630144541951441_ORdGradInc_k_25-Pueyo_APDR-conf_424_1
Workunit 26328592
Created 30 Jun 2024, 12:45:48 UTC
Sent 30 Jun 2024, 14:08:55 UTC
Report deadline 3 Jul 2024, 23:44:55 UTC
Received 3 Jul 2024, 14:02:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 225166
Run time 1 hours 50 min 56 sec
CPU time 1 hours 50 min 39 sec
Validate state Valid
Credit 58.45
Device peak FLOPS 3.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.84 MB
Peak swap size 6.22 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144541951441_ORdGradInc_k_25-Pueyo_APDR-conf_424.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144541951441_ORdGradInc_k_25-Pueyo_APDR-conf_424_1_r79566637_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630144541951441_ORdGradInc_k_25-Pueyo_APDR-conf_424_1_r79566637_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 117.338595
     * GNaL_b in INaL: 0.004933
     * Gto_b in Ito: 0.087122
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032048
     * GKs_b in IKs: 0.002135
     * GK1_b in IK1: 0.180654
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 67.193012
     * GKb_b in IKb: 0.003842
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.048651
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11204537, states[0] = -94.913858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26632710, states[0] = -61.000439, states[40]= 0.000004
Saving checkpoint... 
Iteration: 37688668, states[0] = -94.850588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53725346, states[0] = -94.902067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69394242, states[0] = -95.007992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84845726, states[0] = -94.989525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101020618, states[0] = 20.053634, states[40]= 0.009623
Saving checkpoint... 
Iteration: 116908727, states[0] = -95.005948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132648839, states[0] = -82.790547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148289441, states[0] = -94.955033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164259592, states[0] = -94.929984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180133051, states[0] = -58.847434, states[40]= 0.000006
Saving checkpoint... 
Iteration: 195534189, states[0] = 16.073001, states[40]= 0.005742
Saving checkpoint... 
Iteration: 211137775, states[0] = -64.666244, states[40]= 0.000002
Saving checkpoint... 
Iteration: 226533509, states[0] = 16.310821, states[40]= 0.005810
Saving checkpoint... 
Iteration: 242090677, states[0] = -15.178801, states[40]= 0.001440
Saving checkpoint... 
Iteration: 257537896, states[0] = 14.740773, states[40]= 0.005444
Saving checkpoint... 
Iteration: 273095316, states[0] = -19.713163, states[40]= 0.000966
Saving checkpoint... 
Iteration: 288493944, states[0] = -95.017247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303823056, states[0] = -94.974480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319343177, states[0] = -94.983734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335005396, states[0] = 27.182503, states[40]= 0.136861
Saving checkpoint... 
Iteration: 350406940, states[0] = -95.003630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365810147, states[0] = -94.967454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381495890, states[0] = -95.017376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396835180, states[0] = -94.980218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412326547, states[0] = -94.976151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428096074, states[0] = -20.456451, states[40]= 0.000912
Saving checkpoint... 
Iteration: 443604441, states[0] = -28.671013, states[40]= 0.000489
Saving checkpoint... 
Iteration: 458850462, states[0] = -94.986581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474530547, states[0] = 17.304188, states[40]= 0.006173
Saving checkpoint... 
Iteration: 490083999, states[0] = -8.993240, states[40]= 0.002548
Saving checkpoint... 
Iteration: 505564823, states[0] = 3.447117, states[40]= 0.004606
Saving checkpoint... 
Iteration: 520587860, states[0] = -12.486035, states[40]= 0.001863
Saving checkpoint... 
Iteration: 535980726, states[0] = -95.015673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551348906, states[0] = -94.985918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566535219, states[0] = 15.712692, states[40]= 0.005647
Saving checkpoint... 
Iteration: 581715727, states[0] = -94.875881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597320658, states[0] = -94.973072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612912997, states[0] = -95.004818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628327122, states[0] = -94.976307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639555777, states[0] = 7.591260, states[40]= 0.004855
Saving checkpoint... 
Iteration: 655401131, states[0] = -95.002092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671133858, states[0] = -59.777652, states[40]= 0.000005
Saving checkpoint... 
Iteration: 682409850, states[0] = -95.004090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693988655, states[0] = -95.016455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709915867, states[0] = -95.005372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725347392, states[0] = -94.985216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741079125, states[0] = -5.073068, states[40]= 0.003378
Saving checkpoint... 
Iteration: 756945954, states[0] = -95.010845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767789121, states[0] = -94.953730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783683536, states[0] = -94.820242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799321412, states[0] = -94.973345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814879448, states[0] = -94.996215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830203286, states[0] = -94.855937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845735097, states[0] = -94.902260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861389173, states[0] = -94.998928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877047233, states[0] = 11.134922, states[40]= 0.005040
Saving checkpoint... 
Iteration: 892835317, states[0] = -94.979992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908807543, states[0] = -94.965618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924724654, states[0] = -94.888542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940210963, states[0] = -94.868349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955887239, states[0] = -94.998349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971400527, states[0] = -95.001763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986716841, states[0] = -94.877311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002022987, states[0] = 19.508480, states[40]= 0.008169
Saving checkpoint... 
Iteration: 1017502825, states[0] = 38.851266, states[40]= 0.113568
Saving checkpoint... 
Iteration: 1033051550, states[0] = 9.376940, states[40]= 0.004939
Saving checkpoint... 
Iteration: 1048080878, states[0] = -6.412307, states[40]= 0.003099
Saving checkpoint... 
Iteration: 1063529612, states[0] = 17.604055, states[40]= 0.006317
Saving checkpoint... 
Iteration: 1078770165, states[0] = -94.938658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093977828, states[0] = -95.015015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109030394, states[0] = 17.353828, states[40]= 0.006196
Saving checkpoint... 
Iteration: 1124499339, states[0] = -95.017282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139993125, states[0] = -95.016661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154892219, states[0] = -94.999567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170418960, states[0] = -95.005745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183425685, states[0] = -95.007065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196038894, states[0] = 14.370196, states[40]= 0.005381
Saving checkpoint... 
Iteration: 1211821682, states[0] = -94.973246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226934003, states[0] = -95.008571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242436787, states[0] = -95.009049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258079835, states[0] = -5.605645, states[40]= 0.003268
Saving checkpoint... 
Iteration: 1273635190, states[0] = -61.387817, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1288788743, states[0] = -94.953159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299720542, states[0] = -94.882538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315442218, states[0] = -95.009921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331074056, states[0] = -1.627179, states[40]= 0.004009
Saving checkpoint... 
Iteration: 1344340739, states[0] = -94.982107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360104348, states[0] = -28.579032, states[40]= 0.000493
Saving checkpoint... 
Iteration: 1375721243, states[0] = -94.883497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391478594, states[0] = -95.014933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407248321, states[0] = -94.917285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423244713, states[0] = -94.913292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438962453, states[0] = -95.012873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454454469, states[0] = -95.011739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470175867, states[0] = -94.802912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485906685, states[0] = -95.002914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501289099, states[0] = -26.466115, states[40]= 0.000571
Saving checkpoint... 
Iteration: 1516497781, states[0] = -95.232179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1532246096, states[0] = -94.983353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1547856221, states[0] = -95.071337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1558957469, states[0] = -95.078950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574512032, states[0] = -57.611411, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1590090949, states[0] = -32.512654, states[40]= 0.000325
Saving checkpoint... 
Iteration: 1605748114, states[0] = -95.047924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621093571, states[0] = -95.161678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636638899, states[0] = -94.623166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652123708, states[0] = 18.624468, states[40]= 0.009014
Saving checkpoint... 
Iteration: 1667430647, states[0] = 15.765630, states[40]= 0.007110
Saving checkpoint... 
Iteration: 1683321056, states[0] = 19.582707, states[40]= 0.010596
Saving checkpoint... 
Iteration: 1699261574, states[0] = -1.728142, states[40]= 0.004481
Saving checkpoint... 
Iteration: 1714712108, states[0] = -95.191087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730243318, states[0] = -94.968543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1745799327, states[0] = -42.361605, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1761295202, states[0] = -95.265570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776493674, states[0] = -95.163033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791677752, states[0] = -17.762466, states[40]= 0.001263
Saving checkpoint... 
Iteration: 1806978556, states[0] = -95.058506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817936911, states[0] = -95.042420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833481937, states[0] = -95.036834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848481702, states[0] = -95.028999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863826728, states[0] = -94.984302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879260243, states[0] = -94.934859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894504836, states[0] = 28.667693, states[40]= 0.144107
Saving checkpoint... 
Iteration: 1909872517, states[0] = -94.995702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1925291315, states[0] = -94.956019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940405622, states[0] = -95.003285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955339259, states[0] = -94.981668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970684639, states[0] = -94.822036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986115561, states[0] = -39.754619, states[40]= 0.000121
Saving checkpoint... 
Iteration: 2001352129, states[0] = -94.986437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016723314, states[0] = -94.886099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2032198950, states[0] = -94.847844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047510104, states[0] = 22.435410, states[40]= 0.053059
Saving checkpoint... 
Iteration: 2062587097, states[0] = -11.775157, states[40]= 0.001992
Saving checkpoint... 
Iteration: 2077855427, states[0] = -94.987495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093229253, states[0] = -94.894022, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.892616
 - CaMKt in component CaMK (millimolar): 0.006643
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.734851
 - nass in component intracellular_ions (millimolar): 6.734909
 - ki in component intracellular_ions (millimolar): 145.247644
 - kss in component intracellular_ions (millimolar): 145.247625
 - cansr in component intracellular_ions (millimolar): 1.291845
 - cajsr in component intracellular_ions (millimolar): 1.254802
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003622
 - hf in component INa (dimensionless): 0.879840
 - hs in component INa (dimensionless): 0.879837
 - j in component INa (dimensionless): 0.879813
 - hsp in component INa (dimensionless): 0.725533
 - jp in component INa (dimensionless): 0.879797
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.711404
 - hLp in component INaL (dimensionless): 0.457024
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.628024
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.704553
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940924
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999902
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001517
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.324605
 - xs1 in component IKs (dimensionless): 0.229827
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997340
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:47:38 (412): called boinc_finish(0)

</stderr_txt>
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